iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ssc-116397

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

CT954284

Gene Name

USP30

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000009940.2	ENSSSCT00000010892.2	ENSSSCP00000010607.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.70e-70	237.5	69	501

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw...kskkkavsprellkalkkeaeefsgy 87
           Gl NlgNtC+mNS+LQ Ls++p + + l e +++ +++++++ +++ l+ +l +l+++l     +++++ + + ll++l+++  ++s++
   Q: 69   GLVNLGNTCFMNSLLQGLSACPTFIKWLEEFTTQYTRDQKEPPQHQYLSLTLLHLLKALScqeVTDEEVLDASCLLDVLRMYRWQISSF 157
           9*****************************77777777888889999************888899999********************* PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde..........aeekkkkknkslisdlFqgqlksqikclecdnvs.sr 165
           e+qDa+E+++++ ++le+e    ++ +++++++ ++ e++ e          + + +++ n+   ++ F+g+l+s+++c++c+++s +r
   Q: 158  EEQDAHELFHVITSSLEDER--DHQPRVTHLFDVHSLEQQPEitprqitcrtRGSPHPMFNHWKSQHPFHGRLTSNMVCKHCEHQSpVR 244
           ******************99..77899999999998888888999999**999999********************************* PP
   S: 166  eepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekck...............kkqeaekklklkklPevLilhLkRfsf 239
           +++f +lsl++p  +  ++++l++cL++f + e++++   + c++c+               ++++ +k+lkl klP++L++hL+R s+
   Q: 245  FDTFDSLSLSIPAATWGHPLTLDHCLHHFISSESVRD---VVCDNCTkieakgtlngekvehQRTTFVKQLKLGKLPQCLCIHLQRLSW 330
           ***********************************97...9******8888888888888777777*********************** PP
   S: 240  seeqksrekinkkvefpleLdlspfcts............................................................. 267
           s++ + + k +++v+f + L ++ +  +                                                             
   Q: 331  SSH-GTPLKRHEHVQFSEFLMMDIYKYHllghkpgprgpepcrkagpalevqdgpaapksvrsqpggpktqmlmngacsppflptlpap 418
           998.8888********9888888666667789999999999999998888888888888888887777777777777777777777777 PP
   S: 268  ........peekqkekkkYeLiavvvHsGslssGHYvayvkn.........ekgkWllfdDskVtevkeeevleetgstaYvlfYkr 337
                   p+ ++ + + ++L+avvvH+G ++sGH+v+y ++         ++++Wl ++D++V++ + +evl+   s+aY+lfY+r
   Q: 419  vpfplpavPDHSS-SAYLFQLMAVVVHHGDMHSGHFVTYRRSppsaknplsTSNQWLWISDDTVRKASLQEVLS---SSAYLLFYER 501
           7777776644333.299*************************9999888888999*******************...********98 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MLSSRAEAAM TAADRAIQRF LRTGAAVRYK VMKNWGVIGG IAAALAAGIY VIWGPITERK 60
KRRKGLVPGL VNLGNTCFMN SLLQGLSACP TFIKWLEEFT TQYTRDQKEP PQHQYLSLTL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTACTCTAGT CCTCCGGAAA GAACTACTTC CGGTTCTTCC GGGAGCCCGT CCTGCGGTCT 60
ACCCTCCCCG AAGGAGCTGG GACTTTGGCC GTGGGTTCCG CCGCCTCCGG AGCCCTCGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005741--C:mitochondrial outer membrane
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008053--P:mitochondrial fusion
GO:0000422--P:mitophagy
GO:0035871--P:protein K11-linked deubiquitination
GO:0044313--P:protein K6-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ssc:100153782

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000204	Aegilops tauschii	27.04	3.00e-18	85.90
IUUC-Aml-001733	Ailuropoda melanoleuca	91.73	0.00e+00	862.00
IUUC-Atr-002510	Amborella trichopoda	24.66	3.00e-21	96.70
IUUC-Apl-003645	Anas platyrhynchos	72.20	1.00e-107	381.00
IUUC-Aca-004583	Anolis carolinensis	67.11	3.00e-24	102.00
IUUC-Aly-005754	Arabidopsis lyrata	24.37	4.00e-20	92.40
IUUC-Ath-007622	Arabidopsis thaliana	26.16	6.00e-22	98.60
IUUC-Ame-010896	Astyanax mexicanus	60.88	3.00e-152	531.00
IUUC-Bta-012321	Bos taurus	93.62	0.00e+00	877.00
IUUC-Bdi-014795	Brachypodium distachyon	27.60	1.00e-18	87.40
IUUC-Bol-015637	Brassica oleracea	26.04	3.00e-22	99.80
IUUC-Bra-016801	Brassica rapa	25.73	1.00e-23	104.00
IUUC-Cel-018308	Caenorhabditis elegans	28.42	3.00e-36	145.00
IUUC-Cja-018826	Callithrix jacchus	91.51	0.00e+00	899.00
IUUC-Cfa-021206	Canis familiaris	90.38	0.00e+00	873.00
IUUC-Cpo-021343	Cavia porcellus	89.22	0.00e+00	828.00
IUUC-Csa-023419	Chlorocebus sabaeus	91.10	0.00e+00	897.00
IUUC-Cho-024475	Choloepus hoffmanni	88.00	2.00e-135	475.00
IUUC-Cgl-026621	Colletotrichum gloeosporioides	21.80	1.00e-12	67.80
IUUC-Cne-027061	Cryptococcus neoformans	25.10	3.00e-10	60.50
IUUC-Dre-027563	Danio rerio	58.01	1.00e-154	539.00
IUUC-Dno-029929	Dasypus novemcinctus	91.10	0.00e+00	882.00
IUUC-Dor-030166	Dipodomys ordii	80.08	0.00e+00	719.00
IUUC-Dme-031627	Drosophila melanogaster	33.57	2.00e-34	139.00
IUUC-Ete-032634	Echinops telfairi	79.30	0.00e+00	684.00
IUUC-Eca-033968	Equus caballus	90.82	0.00e+00	826.00
IUUC-Eeu-035279	Erinaceus europaeus	81.71	4.00e-58	218.00
IUUC-Fca-036525	Felis catus	92.65	0.00e+00	893.00
IUUC-Fal-036606	Ficedula albicollis	73.39	5.00e-159	553.00
IUUC-Gmo-038726	Gadus morhua	55.23	1.00e-143	502.00
IUUC-Gga-040718	Gallus gallus	74.94	6.00e-162	563.00
IUUC-Gac-042645	Gasterosteus aculeatus	57.26	5.00e-151	527.00
IUUC-Gma-042890	Glycine max	24.95	2.00e-24	107.00
IUUC-Ggo-045021	Gorilla gorilla	91.10	0.00e+00	895.00
IUUC-Hsa-045832	Homo sapiens	91.10	0.00e+00	895.00
IUUC-Itr-048392	Ictidomys tridecemlineatus	91.22	0.00e+00	828.00
IUUC-Lch-050662	Latimeria chalumnae	69.07	8.00e-177	612.00
IUUC-Lpe-051078	Leersia perrieri	26.45	8.00e-31	128.00
IUUC-Loc-052611	Lepisosteus oculatus	66.73	3.00e-180	624.00
IUUC-Lma-053048	Leptosphaeria maculans	20.28	8.00e-15	75.50
IUUC-Laf-053752	Loxodonta africana	90.61	0.00e+00	819.00
IUUC-Mcc-054892	Macaca mulatta	91.49	0.00e+00	900.00
IUUC-Meu-056673	Macropus eugenii	73.89	4.00e-161	560.00
IUUC-Mtr-057976	Medicago truncatula	26.21	4.00e-32	132.00
IUUC-Mla-058970	Melampsora laricipopulina	21.43	2.00e-19	90.50
IUUC-Mga-059543	Meleagris gallopavo	75.72	0.00e+00	663.00
IUUC-Mmr-061534	Microcebus murinus	90.72	0.00e+00	860.00
IUUC-Mdo-062140	Monodelphis domestica	68.77	9.00e-166	576.00
IUUC-Mmu-063673	Mus musculus	87.81	0.00e+00	822.00
IUUC-Mpu-066328	Mustela putorius furo	90.91	0.00e+00	850.00
IUUC-Mlu-067938	Myotis lucifugus	91.88	0.00e+00	898.00
IUUC-Nle-069426	Nomascus leucogenys	89.59	0.00e+00	801.00
IUUC-Opr-070796	Ochotona princeps	82.10	5.00e-119	421.00
IUUC-Ont-072248	Oreochromis niloticus	57.78	3.00e-155	541.00
IUUC-Oan-072916	Ornithorhynchus anatinus	79.14	0.00e+00	760.00
IUUC-Ocu-074459	Oryctolagus cuniculus	83.59	0.00e+00	636.00
IUUC-Oba-075765	Oryza barthii	26.25	1.00e-29	124.00
IUUC-Obr-076005	Oryza brachyantha	27.49	3.00e-32	132.00
IUUC-Ogl-077916	Oryza glaberrima	26.74	3.00e-33	135.00
IUUC-Ogu-078263	Oryza glumaepatula	26.64	1.00e-30	127.00
IUUC-Oin-080096	Oryza indica	26.65	4.00e-24	105.00
IUUC-Ome-081928	Oryza meridionalis	26.69	2.00e-31	130.00
IUUC-Oni-082424	Oryza nivara	26.50	2.00e-30	126.00
IUUC-Oru-085117	Oryza rufipogon	26.50	2.00e-30	126.00
IUUC-Ola-087429	Oryzias latipes	56.50	9.00e-150	523.00
IUUC-Oga-087981	Otolemur garnettii	90.91	0.00e+00	857.00
IUUC-Oar-089927	Ovis aries	93.81	0.00e+00	879.00
IUUC-Ptr-090878	Pan troglodytes	91.10	0.00e+00	895.00
IUUC-Pan-092698	Papio anubis	91.49	0.00e+00	900.00
IUUC-Psi-093451	Pelodiscus sinensis	75.71	0.00e+00	708.00
IUUC-Ppa-096015	Physcomitrella patens	25.53	1.00e-09	58.50
IUUC-Pfo-096096	Poecilia formosa	57.88	2.00e-155	541.00
IUUC-Pab-098676	Pongo abelii	89.94	0.00e+00	874.00
IUUC-Pca-100418	Procavia capensis	95.40	1.00e-129	456.00
IUUC-Ppe-101898	Prunus persica	24.85	1.00e-24	107.00
IUUC-Pva-103018	Pteropus vampyrus	89.75	0.00e+00	860.00
IUUC-Pgr-103423	Puccinia graminis	25.94	2.00e-10	61.20
IUUC-Pte-104330	Pyrenophora teres	21.96	1.00e-14	74.70
IUUC-Pyt-104518	Pyrenophora triticirepentis	22.20	3.00e-18	86.70
IUUC-Rno-105708	Rattus norvegicus	87.43	0.00e+00	817.00
IUUC-Sha-106971	Sarcophilus harrisii	78.16	0.00e+00	760.00
IUUC-Sit-110442	Setaria italica	27.89	1.00e-28	120.00
IUUC-Sly-110928	Solanum lycopersicum	23.47	7.00e-15	74.70
IUUC-Stu-112223	Solanum tuberosum	24.40	2.00e-15	76.60
IUUC-Sbi-113851	Sorghum bicolor	40.54	2.00e-09	55.80
IUUC-Tgu-117446	Taeniopygia guttata	68.44	0.00e+00	629.00
IUUC-Tru-118268	Takifugu rubripes	57.37	2.00e-140	492.00
IUUC-Tsy-119484	Tarsius syrichta	84.92	4.00e-49	188.00
IUUC-Tni-119735	Tetraodon nigroviridis	53.36	8.00e-122	430.00
IUUC-Tca-121660	Theobroma cacao	25.14	5.00e-29	122.00
IUUC-Tae-125383	Triticum aestivum	28.51	9.00e-29	121.00
IUUC-Tur-126458	Triticum urartu	28.03	1.00e-26	114.00
IUUC-Tbe-127740	Tupaia belangeri	84.53	0.00e+00	768.00
IUUC-Ttr-129273	Tursiops truncatus	92.07	0.00e+00	853.00
IUUC-Vvi-131177	Vitis vinifera	27.99	3.00e-20	93.20
IUUC-Xtr-132374	Xenopus tropicalis	65.60	1.00e-170	592.00
IUUC-Xma-133267	Xiphophorus maculatus	59.80	6.00e-158	550.00
IUUC-Zma-135796	Zea mays	25.46	1.00e-25	110.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence