iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tgu-117446

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01028959

Gene Name

USP30

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000007057.1	ENSTGUT00000007339.1	ENSTGUP00000007267.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.10e-70	238.3	42	466

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelw...kskkkavsprellkalkkeaeefsg 86
           Gl NlgNtC+mNS+LQ Ls++p++ + l e   + ++++e+ +e++++l+ +l +l+++l     +++ + + + ll++l++   ++s+
   Q: 42   GLLNLGNTCFMNSLLQGLSSCPSFIRWLEEfTAQYRTEQEKAPEHQQHLSVTLLQLLRALScqeVTEDDVLDASCLLEVLRMNRWQISS 130
           9*****************************86667777777899999*************888889999******************** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.........aeekkkkknkslisdlFqgqlksqikclecdnvs.sr 165
           +e+qDa+E++++l ++le+e    ++ +++++++ ++ e++++         + + ++++n+   ++ F+g+l+s+++c++c+++s +r
   Q: 131  FEEQDAHELFHVLTSSLEDER--DRQPRVTHLFDVQSLEQPEIiqkqiscrtRGSLPPMSNHWKTQHPFHGRLTSNMVCKHCEHQSpVR 217
           ********************9..679999999999999999999999999988889999999*************************** PP
   S: 166  eepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekck...............kkqeaekklklkklPevLilhLkRfsf 239
           +++f +lsl++p      + +l++cL++f + e++++   + c++c+               ++++ +k+lkl klP++L++hL+R s+
   Q: 218  FDTFDSLSLSIPAAVWGRPMTLDHCLHHFISSESVKD---VVCDNCTkiqaegilngqsienQRTTFVKQLKLGKLPQCLCIHLQRLSW 303
           ***********************************97...9******5555555555555555555*********************** PP
   S: 240  seeqksrekinkkvefpleLdls..pfcts...........peekqke......................................... 274
           s++ + + k +++v+f++ L ++  ++ +            +     +                                         
   Q: 304  SNQ-GTPLKRHEHVQFNEFLVMDiyKYRVPgpkscqeqlsqK-----Nseettpgmkdgragkpsgtsfankmvqlflqgiksflqdqv 386
           996.8889*********8877773344433555444444330.....266677888888888888888888888888888888888888 PP
   S: 275  .................kkkYeLiavvvHsGslssGHYvayvkn...ekgkWllfdDskVtevkeeevleetgstaYvlfYkr 337
                             + Y+L+avvvH+G ++sGH+v++ +    +  +Wl ++D++V+  + +evl    ++aY+lfY+r
   Q: 387  mssilmwgpllqqelapLYLYRLMAVVVHHGDMHSGHFVTFRRApgaRGSQWLWISDESVRRASLHEVLA---ASAYLLFYER 466
           88888899999888888***************************5544555*******************...********98 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

RHRAMRSWGV LGGAAAALAA GIYVLWGPIS GRKRRRRGLV PGLLNLGNTC FMNSLLQGLS 60
SCPSFIRWLE EFTAQYRTEQ EKAPEHQQHL SVTLLQLLRA LSCQEVTEDD VLDASCLLEV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGCACCGAG CCATGCGGAG CTGGGGGGTG CTGGGGGGCG CGGCGGCGGC GCTGGCGGCC 60
GGCATTTACG TCCTGTGGGG CCCCATCAGC GGCAGGAAGC GGCGGCGGAG AGGTACCGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005741--C:mitochondrial outer membrane
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008053--P:mitochondrial fusion
GO:0000422--P:mitophagy
GO:0035871--P:protein K11-linked deubiquitination
GO:0044313--P:protein K6-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000204	Aegilops tauschii	25.58	2.00e-21	96.70
IUUC-Aml-001733	Ailuropoda melanoleuca	69.26	1.00e-177	615.00
IUUC-Atr-002510	Amborella trichopoda	26.28	1.00e-23	104.00
IUUC-Apl-003645	Anas platyrhynchos	72.49	2.00e-108	384.00
IUUC-Aca-004583	Anolis carolinensis	77.05	4.00e-23	98.60
IUUC-Aly-005754	Arabidopsis lyrata	26.42	6.00e-26	111.00
IUUC-Ath-007622	Arabidopsis thaliana	28.32	1.00e-24	107.00
IUUC-Ate-010439	Aspergillus terreus	20.98	2.00e-10	60.80
IUUC-Ame-010896	Astyanax mexicanus	59.10	2.00e-155	541.00
IUUC-Bta-012321	Bos taurus	68.45	7.00e-178	616.00
IUUC-Bci-013590	Botrytis cinerea	22.98	3.00e-17	83.60
IUUC-Bol-015637	Brassica oleracea	27.53	3.00e-24	105.00
IUUC-Bra-016801	Brassica rapa	27.53	2.00e-24	106.00
IUUC-Cel-018308	Caenorhabditis elegans	29.39	3.00e-44	172.00
IUUC-Cja-018826	Callithrix jacchus	70.04	0.00e+00	632.00
IUUC-Cfa-021206	Canis familiaris	69.88	2.00e-180	625.00
IUUC-Cpo-021343	Cavia porcellus	70.19	1.00e-179	622.00
IUUC-Csa-023419	Chlorocebus sabaeus	70.39	0.00e+00	633.00
IUUC-Cho-024475	Choloepus hoffmanni	61.45	7.00e-94	337.00
IUUC-Cne-027061	Cryptococcus neoformans	29.24	2.00e-14	74.30
IUUC-Dre-027563	Danio rerio	58.42	2.00e-152	532.00
IUUC-Dno-029929	Dasypus novemcinctus	69.36	7.00e-180	623.00
IUUC-Dor-030166	Dipodomys ordii	59.01	1.00e-144	506.00
IUUC-Dme-031627	Drosophila melanogaster	33.82	4.00e-38	152.00
IUUC-Ete-032634	Echinops telfairi	66.18	4.00e-168	584.00
IUUC-Eca-033968	Equus caballus	69.77	3.00e-179	621.00
IUUC-Eeu-035279	Erinaceus europaeus	70.30	9.00e-51	194.00
IUUC-Fca-036525	Felis catus	68.93	0.00e+00	634.00
IUUC-Fal-036606	Ficedula albicollis	91.64	0.00e+00	654.00
IUUC-Gmo-038726	Gadus morhua	55.44	2.00e-138	485.00
IUUC-Gga-040718	Gallus gallus	84.47	9.00e-177	612.00
IUUC-Gac-042645	Gasterosteus aculeatus	55.79	1.00e-139	489.00
IUUC-Gma-042890	Glycine max	23.71	9.00e-22	97.80
IUUC-Ggo-045021	Gorilla gorilla	70.39	0.00e+00	633.00
IUUC-Hsa-045832	Homo sapiens	70.39	0.00e+00	633.00
IUUC-Itr-048392	Ictidomys tridecemlineatus	70.19	0.00e+00	627.00
IUUC-Kpa-049268	Komagataella pastoris	23.27	4.00e-19	89.40
IUUC-Lch-050662	Latimeria chalumnae	66.81	1.00e-174	605.00
IUUC-Lpe-051078	Leersia perrieri	28.72	6.00e-32	131.00
IUUC-Loc-052611	Lepisosteus oculatus	61.95	6.00e-161	560.00
IUUC-Laf-053752	Loxodonta africana	69.69	5.00e-180	623.00
IUUC-Mcc-054892	Macaca mulatta	70.39	0.00e+00	633.00
IUUC-Meu-056673	Macropus eugenii	62.18	2.00e-127	447.00
IUUC-Mor-057143	Magnaporthe oryzae	21.00	3.00e-11	63.50
IUUC-Mtr-057976	Medicago truncatula	25.43	2.00e-31	130.00
IUUC-Mla-058970	Melampsora laricipopulina	24.01	5.00e-25	108.00
IUUC-Mga-059543	Meleagris gallopavo	78.60	0.00e+00	679.00
IUUC-Mmr-061534	Microcebus murinus	69.36	0.00e+00	633.00
IUUC-Mdo-062140	Monodelphis domestica	58.10	3.00e-138	484.00
IUUC-Mmu-063673	Mus musculus	68.32	3.00e-178	617.00
IUUC-Mpu-066328	Mustela putorius furo	70.52	0.00e+00	626.00
IUUC-Mlu-067938	Myotis lucifugus	69.96	0.00e+00	640.00
IUUC-Nfi-068306	Neosartorya fischeri	22.87	4.00e-13	69.30
IUUC-Nle-069426	Nomascus leucogenys	70.11	1.00e-168	585.00
IUUC-Opr-070796	Ochotona princeps	60.00	9.00e-80	290.00
IUUC-Ont-072248	Oreochromis niloticus	58.85	3.00e-146	511.00
IUUC-Oan-072916	Ornithorhynchus anatinus	69.01	0.00e+00	631.00
IUUC-Ocu-074459	Oryctolagus cuniculus	68.23	5.00e-147	513.00
IUUC-Oba-075765	Oryza barthii	27.31	4.00e-30	125.00
IUUC-Obr-076005	Oryza brachyantha	26.16	2.00e-27	116.00
IUUC-Ogl-077916	Oryza glaberrima	28.13	8.00e-32	131.00
IUUC-Ogu-078263	Oryza glumaepatula	27.50	2.00e-30	126.00
IUUC-Oin-080096	Oryza indica	27.76	4.00e-22	98.60
IUUC-Ome-081928	Oryza meridionalis	26.80	1.00e-29	124.00
IUUC-Oni-082424	Oryza nivara	27.50	1.00e-30	127.00
IUUC-Oru-085117	Oryza rufipogon	27.50	1.00e-30	127.00
IUUC-Ola-087429	Oryzias latipes	53.17	4.00e-134	471.00
IUUC-Oga-087981	Otolemur garnettii	69.73	0.00e+00	632.00
IUUC-Oar-089927	Ovis aries	68.45	4.00e-178	617.00
IUUC-Ptr-090878	Pan troglodytes	70.39	0.00e+00	633.00
IUUC-Pan-092698	Papio anubis	70.39	0.00e+00	633.00
IUUC-Psi-093451	Pelodiscus sinensis	71.87	0.00e+00	647.00
IUUC-Ppa-096015	Physcomitrella patens	24.21	7.00e-15	75.50
IUUC-Pfo-096096	Poecilia formosa	57.41	6.00e-142	496.00
IUUC-Pab-098676	Pongo abelii	69.73	5.00e-179	620.00
IUUC-Pca-100418	Procavia capensis	80.92	2.00e-110	392.00
IUUC-Ppe-101898	Prunus persica	27.41	1.00e-24	107.00
IUUC-Pva-103018	Pteropus vampyrus	67.49	4.00e-173	600.00
IUUC-Pgr-103686	Puccinia graminis	24.44	3.00e-11	63.50
IUUC-Rno-105708	Rattus norvegicus	68.32	2.00e-177	614.00
IUUC-Sha-106971	Sarcophilus harrisii	69.71	0.00e+00	631.00
IUUC-Ssl-108648	Sclerotinia sclerotiorum	23.09	8.00e-17	82.00
IUUC-Sit-110442	Setaria italica	27.01	2.00e-26	112.00
IUUC-Sly-110928	Solanum lycopersicum	26.69	4.00e-17	82.00
IUUC-Stu-112223	Solanum tuberosum	26.00	6.00e-18	84.70
IUUC-Ssc-116397	Sus scrofa	67.97	2.00e-176	611.00
IUUC-Tru-118268	Takifugu rubripes	55.32	2.00e-133	469.00
IUUC-Tsy-119484	Tarsius syrichta	72.41	1.00e-26	114.00
IUUC-Tni-119735	Tetraodon nigroviridis	53.22	3.00e-116	411.00
IUUC-Tca-121660	Theobroma cacao	27.12	1.00e-25	111.00
IUUC-Tae-125203	Triticum aestivum	25.87	3.00e-27	115.00
IUUC-Tur-126458	Triticum urartu	25.85	7.00e-26	111.00
IUUC-Tbe-127740	Tupaia belangeri	64.39	6.00e-161	560.00
IUUC-Ttr-129273	Tursiops truncatus	68.04	4.00e-172	597.00
IUUC-Vda-129789	Verticillium dahliae	22.27	1.00e-10	61.60
IUUC-Vvi-131177	Vitis vinifera	25.42	2.00e-24	106.00
IUUC-Xtr-132374	Xenopus tropicalis	65.76	2.00e-172	598.00
IUUC-Xma-133267	Xiphophorus maculatus	56.24	2.00e-148	518.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence