iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bol-015191

Ensembl Protein ID

Bo8g115390.1

UniProt Accession

A0A0D3DYZ2; A0A0D3DYZ2_BRAOL

Protein Name

Ubiquitinyl hydrolase 1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Bo8g115390	Bo8g115390.1	Bo8g115390.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.60e-81	275.0	198	878

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgyeqqDaqEfl 96
           Gl NlgNtC++NS++Q L+++ +lr+ +l+    +++     +   +l++sl+klf+e+    + k++v+pr+++++++++a++f+gy+q+D++E+l
   Q: 198  GLVNLGNTCFFNSIMQNLLSLDQLRSHFLK---DDVS-----GVGLPLASSLRKLFAEMKpeAGLKSVVNPRAFFATFCAKAPQFRGYDQHDSHELL 286
           9*****************************...4444.....34579************99999********************************* PP
   S: 97   aflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke........ 185
           ++lld+l++e +    ++k +             +++k + + +l++ +F+g+++s + c ec+++s+ +epfldlslpvp k++  k+        
   Q: 287  RCLLDSLSTEESA---WRKRR--------GGVCDDDEKATTTATLVESVFGGETSSIVSCIECGHSSKIYEPFLDLSLPVPFKKTPPKKqqalsrak 372
           **********922...22222........2233467899999***************************************99987666999***** PP
   S: 186  ................................................................................................. 185
                                                                                                            
   Q: 373  kgkfppkrtaknvskvskvskvlpakvatadsdngavsetpsvitldnkeasenvaqsdtvfdsfwldviapepagdetnldmedsvsdktptpeas 469
           ************************************************************************************************* PP
   S: 186  ................................................................................................. 185
                                                                                                            
   Q: 470  qtvpcpnipantsvslgdqasegnaerliqdsdefakadekdvqatqsdectatsaisaeisqdscigldpglgessssvnpwdeeevplmvadsqv 566
           ************************************************************************************************* PP
   S: 186  .......................................................................................slqdcLesft 195
                                                                                                  s++ cL++ft
   Q: 567  lympykenvssydegeasssfvsgdnqepenndfvglgglfdepevtegpvvfgppckpeassgvvgfmafssesdpeeiddsdspvSVERCLAHFT 663
           ************************************************************************************************* PP
   S: 196  keeelegenkyycekck..................................................................kkqeaekklklkkl 226
           k+e l ++n+++ce+c                                                                    k++a+k++ l+k+
   Q: 664  KPEILSDDNAWNCENCSknlklqrlrekrkssntssngwvsenedgvlgetdvkqdpsdsgreamssndsesegeedskkvitVKRDATKRVLLNKV 760
           *****************8888888888888888888888888888888888888888888888888888888888888777777777********** PP
   S: 227  PevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn.........ekgk.....Wllf 309
           P+vL++hLkRfs + + ++ +k+n +v f++ +dl++++  ++++++ +  Y+L + v HsG++++GHYvayv+          +  +     W+++
   Q: 761  PPVLTIHLKRFSQDLR-GRLSKLNGHVAFKEVIDLRHYMDPRCSGED-PPVYRLAGLVEHSGTMRGGHYVAYVRGgggkkvkesD--SssssvWYNV 853
           ***********98887.8889********************999985.***************************7776665541..155678**** PP
   S: 310  dDskVtevkeeevleetgstaYvlfYkr 337
           +D +V++v+ ++vl    s+aY+lfY+r
   Q: 854  SDAHVRQVSLDKVLH---SEAYILFYER 878
           ***************...********98 PP

Organism

Brassica oleracea

Protein Sequence
(Fasta)

MGKKAKKKAR TPTKENLTKK VSEHPSEIAE EAVKEKQACV HFDKGLNLDK VLEKIKSSRV 60
IKCHECKEGA KGKGSNKGKH SPSSSSDRKA IWVCLECGCY VCGGVGLPTL PQSHVLKHIR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGAAGA AAGCAAAGAA GAAAGCTCGA ACTCCAACTA AGGAGAATCT CACCAAGAAG 60
GTCTCTGAAC ATCCTAGTGA AATAGCTGAG GAGGCAGTTA AGGAGAAGCA AGCTTGTGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH
PF02148--zf-UBP

SMART

SM00290--ZnF_UBP

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000997	Aegilops tauschii	29.80	2.00e-67	251.00
IUUC-Aca-004284	Anolis carolinensis	28.07	1.00e-31	131.00
IUUC-Bra-017226	Brassica rapa	87.92	0.00e+00	1393.00
IUUC-Csv-026075	Ciona savignyi	28.40	9.00e-21	95.10
IUUC-Cme-027348	Cyanidioschyzon merolae	36.30	7.00e-19	88.60
IUUC-Eeu-034835	Erinaceus europaeus	32.18	1.00e-26	115.00
IUUC-Gmo-039480	Gadus morhua	28.53	1.00e-29	124.00
IUUC-Gma-043919	Glycine max	42.82	5.00e-136	478.00
IUUC-Hvu-047146	Hordeum vulgare	33.53	1.00e-49	192.00
IUUC-Lch-050536	Latimeria chalumnae	27.80	2.00e-31	130.00
IUUC-Loc-052842	Lepisosteus oculatus	28.87	4.00e-30	126.00
IUUC-Mmr-060952	Microcebus murinus	29.39	1.00e-30	127.00
IUUC-Mac-064941	Musa acuminata	35.17	2.00e-113	403.00
IUUC-Oan-073656	Ornithorhynchus anatinus	30.16	3.00e-36	146.00
IUUC-Obr-076743	Oryza brachyantha	39.77	2.00e-49	191.00
IUUC-Oru-084546	Oryza rufipogon	35.71	6.00e-52	199.00
IUUC-Ppa-095584	Physcomitrella patens	31.06	7.00e-54	206.00
IUUC-Pca-101069	Procavia capensis	33.74	3.00e-27	117.00
IUUC-Sja-107712	Schizosaccharomyces japonicus	27.05	2.00e-16	80.90
IUUC-Spo-108149	Schizosaccharomyces pombe	31.65	2.00e-22	100.00
IUUC-Sit-110283	Setaria italica	31.81	1.00e-62	235.00
IUUC-Sbi-113785	Sorghum bicolor	31.31	4.00e-62	233.00
IUUC-Tae-125785	Triticum aestivum	33.71	2.00e-46	181.00
IUUC-Vvi-131230	Vitis vinifera	72.58	3.00e-22	95.90

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence