iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aly-006493

UUCD1 version

UUC-ArL-00618

Ensembl Protein ID

fgenesh2_kg.6__201__AT5G02880.1

UniProt Accession

D7M7X1; D7M7X1_ARALL

Genbank Protein ID

EFH47256.1

Protein Name

Ubiquitin-protein ligase 4

Genbank Nucleotide ID

GL348718

Gene Name

UPL4; ARALYDRAFT_487067

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
fgenesh2_kg.6__201__AT5G02880.1	fgenesh2_kg.6__201__AT5G02880.1	fgenesh2_kg.6__201__AT5G02880.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	5.80e-111	371.8	1142	1509

Active Site

Position(s)	Description	Evidence
1476	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkkrlevefvgEegldlgGvtreflallskelqnpdlglf............lysen..dketlqpnpdsglknp 65
           ++k ++eve+++E g++l G+t+ef++l+s+++qnpdlg++            ++s    +++ l+p+p+sg++++
   Q: 1142 NQKVVIEVEYSEEVGTGL-GPTLEFYTLVSRAFQNPDLGMWrndcssfvgkpgEHSGVlaSSSGLFPRPWSGTSTT 1216
           67889*************.**********************77777777766555544666777777777776655 PP
   S: 66   .ehlklFeflGrllgkalqdgrlldlplsksfyklllgkklsledleevdpelykslkeikena.........esd 131
            ++l+ F +lG++++kalqdgr+ldlp+sk+fykl+lg++ls  d++ vdpel+k++ e++++a         + d
   Q: 1217 sDVLQKFVLLGTVVAKALQDGRVLDLPFSKAFYKLILGQELSSFDIHFVDPELCKTMVELQALArrkkvfneaHGD 1292
           89***********************************************************999666666555226 PP
   S: 132  ieelgldltfs..vseei.....lgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfnev 200
           +  +++dl+f+  + e++     l+ +++++L p ++n +V+ +N+eeY+k++v++++++gi++qveaf++Gfn+v
   Q: 1293 SRPAKCDLSFHgtKIEDLslgfaLPGYTDYDLAPYSDNDMVNLDNLEEYIKAIVNATVCNGIQKQVEAFQSGFNQV 1368
           66666777776335555599999***************************************************** PP
   S: 201  iplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlP 275
           +p+e+l++F+eeele+++cGe + ++++++ +++k+++gyt++sp +++++e+l+ef++e+++afLqFvTgs+rlP
   Q: 1369 FPIEHLRIFNEEELETMLCGErDLFNMNEVLDHIKFDHGYTSSSPPVENLLEILHEFDREQQRAFLQFVTGSPRLP 1444
           *********************999**************************************************** PP
   S: 276  lgGfaelkprlfvirk...dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFels 336
           +gG+a+l+p+l+++rk   d+sd++lPs++TC+nyLkLP Ysske++kekL+yAi+e+  +F+ls
   Q: 1445 HGGLASLNPKLTIVRKhgsDSSDTDLPSVMTCANYLKLPAYSSKEKMKEKLIYAITEGqGSFHLS 1509
           ******************99999***********************************9999985 PP

Organism

Arabidopsis lyrata

Protein Sequence
(Fasta)

MENRGQKRME VVEELPADKR ACNSQDFRPS TSGSSVQAQA NGTSSGHENV DADMDTSSSA 60
SPSSRSDEEQ DKDSDYGSCD SDEEDPRQRV LQDYQRQRSS GDQGKLKSLL ASLTGETDPS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TAAATTTTCC AAAGATAAAA CCCTAGATTC TCATCTTCTT TTCTTCAATC TCTCTGAGAA 60
TTTTTAGGTT TTCGTTACCA ATCTAACGAT TGGGTCAATC TGGTGAAACT TTAAGGTGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

KEGG

aly:ARALYDRAFT_487067

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000935	Aegilops tauschii	45.03	0.00e+00	1090.00
IUUC-Aca-004521	Anolis carolinensis	36.43	8.00e-44	173.00
IUUC-Ath-006679	Arabidopsis thaliana	91.81	0.00e+00	2729.00
IUUC-Bdi-014101	Brachypodium distachyon	45.61	0.00e+00	1162.00
IUUC-Bol-016355	Brassica oleracea	81.11	0.00e+00	2393.00
IUUC-Bra-016937	Brassica rapa	77.80	0.00e+00	2248.00
IUUC-Dno-029954	Dasypus novemcinctus	37.11	2.00e-44	175.00
IUUC-Gma-043952	Glycine max	56.10	0.00e+00	1602.00
IUUC-Hvu-047811	Hordeum vulgare	46.19	0.00e+00	1179.00
IUUC-Lpe-051509	Leersia perrieri	44.90	0.00e+00	1142.00
IUUC-Mtr-058626	Medicago truncatula	54.99	0.00e+00	1572.00
IUUC-Mac-065046	Musa acuminata	44.86	0.00e+00	1131.00
IUUC-Opr-070401	Ochotona princeps	40.14	4.00e-49	190.00
IUUC-Oba-075380	Oryza barthii	44.96	0.00e+00	1078.00
IUUC-Obr-076904	Oryza brachyantha	45.28	0.00e+00	1144.00
IUUC-Ogl-076926	Oryza glaberrima	46.04	0.00e+00	1166.00
IUUC-Ogu-078892	Oryza glumaepatula	45.83	0.00e+00	1126.00
IUUC-Oin-079148	Oryza indica	43.40	0.00e+00	1063.00
IUUC-Olo-081086	Oryza longistaminata	44.00	0.00e+00	1035.00
IUUC-Ome-081955	Oryza meridionalis	44.16	0.00e+00	1104.00
IUUC-Oni-083047	Oryza nivara	44.36	0.00e+00	1102.00
IUUC-Opu-083641	Oryza punctata	45.28	0.00e+00	1113.00
IUUC-Oru-084439	Oryza rufipogon	44.74	0.00e+00	1076.00
IUUC-Osa-085617	Oryza sativa	56.59	5.00e-170	590.00
IUUC-Pop-099725	Populus trichocarpa	58.28	0.00e+00	1669.00
IUUC-Ppe-101229	Prunus persica	58.02	0.00e+00	1672.00
IUUC-Sce-106273	Saccharomyces cerevisiae	37.09	5.00e-78	286.00
IUUC-Sit-110332	Setaria italica	46.10	0.00e+00	1176.00
IUUC-Sly-111552	Solanum lycopersicum	50.92	0.00e+00	1397.00
IUUC-Sbi-114106	Sorghum bicolor	44.45	0.00e+00	1132.00
IUUC-Tgu-117167	Taeniopygia guttata	37.11	7.00e-44	172.00
IUUC-Tca-121574	Theobroma cacao	56.47	0.00e+00	1652.00
IUUC-Tae-124564	Triticum aestivum	46.12	0.00e+00	1177.00
IUUC-Tur-126486	Triticum urartu	45.72	0.00e+00	1107.00
IUUC-Vvi-130904	Vitis vinifera	53.63	0.00e+00	1509.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence