iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cja-019657

UUCD1 version

UUC-CaJ-00201

Ensembl Protein ID

ENSCJAP00000022163.1

UniProt Accession

F6X127; F6X127_CALJA

Genbank Protein ID

JAB40492.1; JAB40493.1; JAB45732.1; JAB45733.1

Protein Name

E3 ubiquitin-protein ligase CHIP

Genbank Nucleotide ID

ACFV01156596; GAMQ01001358; GAMP01007023; GAMP01007022

Gene Name

STUB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000012062.1	ENSCJAT00000023429.1	ENSCJAP00000022163.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	1.70e-26	93.0	226	299

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 1    evpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceenss 74
           ++p+++++ Is+elMr+P+++psGitydr+ Ie++l++ g+ +Pvtr+plt+e+l+Pnl+++++i+a+++en++
   Q: 226  DIPDYLCGKISFELMREPCITPSGITYDRKDIEEHLQRVGHFDPVTRSPLTQEQLIPNLAMKEVIDAFISENGW 299
           69********************************************************************9986 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MKGKEEKEGG ARLGAGGGSP EKSPSAQELK EQGNRLFVGR KYPEAAACYG RAITRNPLVA 60
VYYTNRALCY LKMQQHEQAL ADCRRALELD GQSVKAHFFL GQCQLEMESY DEAIANLQRA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTTTTAGGG AAGCACGCCC TCAGCGAACC AAGGCTGAGG CACCTCACGG AGAAAACCGG 60
ATATATGGGA GGGCCGCCAC CGAGGCCAGT TCTGGAGAGG CCTCGGCGGG GCGGGGCGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0677--Repeat
KW-0802--TPR repeat

Interpro

IPR023114--Elongated_TPR_rpt_dom
IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR019734--TPR_repeat
IPR003613--Ubox_domain
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50005--TPR
PS50293--TPR_REGION
PS51698--U_BOX

Pfam

PF04564--U-box

SMART

SM00028--TPR
SM00504--Ubox

Gene Ontology

GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0070062--C:extracellular exosome
GO:0042405--C:nuclear inclusion body
GO:0005654--C:nucleoplasm
GO:0000151--C:ubiquitin ligase complex
GO:0030018--C:Z disc
GO:0016874--F:ligase activity
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0071218--P:cellular response to misfolded protein
GO:0030968--P:endoplasmic reticulum unfolded protein response
GO:0006515--P:misfolded or incompletely synthesized protein catabolic process
GO:0032091--P:negative regulation of protein binding
GO:0030512--P:negative regulation of transforming growth factor beta receptor signaling pathway
GO:0090035--P:positive regulation of chaperone-mediated protein complex assembly
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0051865--P:protein autoubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0031943--P:regulation of glucocorticoid metabolic process
GO:0031647--P:regulation of protein stability
GO:0030579--P:ubiquitin-dependent SMAD protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000537	Aegilops tauschii	36.43	1.00e-38	152.00
IUUC-Aml-001350	Ailuropoda melanoleuca	96.00	2.00e-145	507.00
IUUC-Atr-003168	Amborella trichopoda	34.11	1.00e-30	126.00
IUUC-Apl-003736	Anas platyrhynchos	87.25	9.00e-132	462.00
IUUC-Aca-004751	Anolis carolinensis	84.51	1.00e-141	495.00
IUUC-Aly-006292	Arabidopsis lyrata	34.88	5.00e-45	174.00
IUUC-Ath-007012	Arabidopsis thaliana	34.52	3.00e-42	164.00
IUUC-Acl-008025	Aspergillus clavatus	32.17	2.00e-36	145.00
IUUC-Afl-008721	Aspergillus flavus	32.41	6.00e-33	134.00
IUUC-Afu-008853	Aspergillus fumigatus	32.17	6.00e-36	144.00
IUUC-Ani-009349	Aspergillus nidulans	30.93	7.00e-34	137.00
IUUC-Ang-009674	Aspergillus niger	32.64	3.00e-33	135.00
IUUC-Aor-010014	Aspergillus oryzae	29.89	2.00e-27	115.00
IUUC-Ate-010467	Aspergillus terreus	30.85	4.00e-27	115.00
IUUC-Ame-011215	Astyanax mexicanus	59.79	5.00e-92	330.00
IUUC-Bgr-011971	Blumeria graminis	29.75	5.00e-26	111.00
IUUC-Bta-013025	Bos taurus	96.35	1.00e-168	585.00
IUUC-Bci-013945	Botrytis cinerea	39.51	6.00e-15	74.70
IUUC-Bdi-014483	Brachypodium distachyon	38.04	3.00e-45	175.00
IUUC-Bol-015676	Brassica oleracea	34.98	4.00e-46	178.00
IUUC-Bra-017897	Brassica rapa	32.21	3.00e-29	121.00
IUUC-Cel-018323	Caenorhabditis elegans	40.79	9.00e-56	209.00
IUUC-Cfa-020470	Canis familiaris	96.10	4.00e-133	466.00
IUUC-Cpo-022033	Cavia porcellus	96.37	3.00e-170	590.00
IUUC-Cre-022896	Chlamydomonas reinhardtii	27.53	4.00e-28	118.00
IUUC-Csa-023038	Chlorocebus sabaeus	98.95	5.00e-162	563.00
IUUC-Cin-025381	Ciona intestinalis	52.31	2.00e-87	315.00
IUUC-Cgl-026524	Colletotrichum gloeosporioides	32.26	7.00e-39	154.00
IUUC-Dre-027610	Danio rerio	79.65	2.00e-136	478.00
IUUC-Dno-030087	Dasypus novemcinctus	94.72	4.00e-168	583.00
IUUC-Dor-031029	Dipodomys ordii	92.28	3.00e-152	530.00
IUUC-Dse-031275	Dothistroma septosporum	31.85	4.00e-28	118.00
IUUC-Dme-031856	Drosophila melanogaster	57.71	4.00e-95	340.00
IUUC-Ete-033087	Echinops telfairi	91.54	2.00e-137	481.00
IUUC-Eca-033512	Equus caballus	96.40	1.00e-145	508.00
IUUC-Eeu-034763	Erinaceus europaeus	89.13	3.00e-96	343.00
IUUC-Fca-036460	Felis catus	96.69	6.00e-160	556.00
IUUC-Fal-037441	Ficedula albicollis	87.41	9.00e-150	522.00
IUUC-Fox-038028	Fusarium oxysporum	31.06	5.00e-38	150.00
IUUC-Fso-038323	Fusarium solani	32.27	8.00e-30	123.00
IUUC-Gmo-038511	Gadus morhua	76.49	2.00e-131	461.00
IUUC-Ggr-039964	Gaeumannomyces graminis	33.33	3.00e-28	118.00
IUUC-Gga-040854	Gallus gallus	87.76	3.00e-149	520.00
IUUC-Gac-042175	Gasterosteus aculeatus	76.14	1.00e-127	448.00
IUUC-Gma-044046	Glycine max	36.59	3.00e-44	171.00
IUUC-Ggo-044512	Gorilla gorilla	98.95	5.00e-162	563.00
IUUC-Hsa-046872	Homo sapiens	98.95	5.00e-162	563.00
IUUC-Hvu-047661	Hordeum vulgare	35.66	1.00e-39	156.00
IUUC-Itr-048871	Ictidomys tridecemlineatus	97.54	3.00e-167	580.00
IUUC-Lch-049988	Latimeria chalumnae	78.67	1.00e-132	465.00
IUUC-Lpe-050693	Leersia perrieri	34.78	5.00e-43	167.00
IUUC-Loc-052195	Lepisosteus oculatus	77.65	8.00e-116	409.00
IUUC-Lma-053207	Leptosphaeria maculans	30.29	3.00e-29	123.00
IUUC-Laf-054584	Loxodonta africana	94.39	4.00e-167	580.00
IUUC-Mcc-054689	Macaca mulatta	98.95	5.00e-162	563.00
IUUC-Meu-055998	Macropus eugenii	88.70	9.00e-84	303.00
IUUC-Mor-057116	Magnaporthe oryzae	34.88	4.00e-42	164.00
IUUC-Mtr-057684	Medicago truncatula	32.85	1.00e-38	152.00
IUUC-Mga-059332	Meleagris gallopavo	87.65	2.00e-131	461.00
IUUC-Mmr-061377	Microcebus murinus	97.54	6.00e-160	556.00
IUUC-Mdo-061963	Monodelphis domestica	90.21	2.00e-147	514.00
IUUC-Mmu-063146	Mus musculus	96.38	2.00e-160	558.00
IUUC-Mac-064932	Musa acuminata	34.47	3.00e-28	118.00
IUUC-Mpu-066418	Mustela putorius furo	96.49	5.00e-167	579.00
IUUC-Mlu-067066	Myotis lucifugus	96.37	2.00e-170	590.00
IUUC-Nfi-068601	Neosartorya fischeri	32.17	9.00e-36	143.00
IUUC-Ncr-068761	Neurospora crassa	41.67	3.00e-17	82.40
IUUC-Nle-069374	Nomascus leucogenys	98.95	5.00e-162	563.00
IUUC-Opr-070765	Ochotona princeps	92.35	4.00e-102	363.00
IUUC-Ont-071996	Oreochromis niloticus	79.30	1.00e-130	459.00
IUUC-Oba-075967	Oryza barthii	36.10	3.00e-44	171.00
IUUC-Obr-076440	Oryza brachyantha	34.53	2.00e-31	131.00
IUUC-Ogl-077495	Oryza glaberrima	36.10	3.00e-44	171.00
IUUC-Ogu-078247	Oryza glumaepatula	36.36	3.00e-40	158.00
IUUC-Oin-079376	Oryza indica	36.10	3.00e-44	171.00
IUUC-Olo-081083	Oryza longistaminata	31.52	6.00e-32	130.00
IUUC-Ome-081935	Oryza meridionalis	29.17	5.00e-21	97.40
IUUC-Oni-082535	Oryza nivara	36.36	3.00e-40	158.00
IUUC-Opu-083794	Oryza punctata	35.15	1.00e-43	170.00
IUUC-Oru-085153	Oryza rufipogon	36.10	6.00e-44	170.00
IUUC-Osa-085936	Oryza sativa	35.82	1.00e-16	79.30
IUUC-Ola-087081	Oryzias latipes	77.54	5.00e-134	470.00
IUUC-Olu-087790	Ostreococcus lucimarinus	32.62	2.00e-32	132.00
IUUC-Oga-088331	Otolemur garnettii	97.36	1.00e-164	571.00
IUUC-Oar-089987	Ovis aries	93.75	3.00e-141	494.00
IUUC-Ptr-090855	Pan troglodytes	98.95	5.00e-162	563.00
IUUC-Pan-092801	Papio anubis	94.39	2.00e-161	561.00
IUUC-Psi-093393	Pelodiscus sinensis	86.06	4.00e-130	456.00
IUUC-Pma-094680	Petromyzon marinus	68.57	2.00e-113	401.00
IUUC-Pno-094913	Phaeosphaeria nodorum	32.76	2.00e-34	139.00
IUUC-Ppa-095976	Physcomitrella patens	34.38	8.00e-44	170.00
IUUC-Pfo-096850	Poecilia formosa	77.19	3.00e-127	447.00
IUUC-Pab-097963	Pongo abelii	98.95	5.00e-162	563.00
IUUC-Pop-098805	Populus trichocarpa	42.86	7.00e-25	106.00
IUUC-Pca-100788	Procavia capensis	95.38	3.00e-169	587.00
IUUC-Ppe-101221	Prunus persica	34.53	1.00e-43	169.00
IUUC-Pva-103076	Pteropus vampyrus	95.05	3.00e-169	587.00
IUUC-Pte-104237	Pyrenophora teres	31.47	1.00e-33	137.00
IUUC-Pyt-104468	Pyrenophora triticirepentis	31.47	9.00e-34	137.00
IUUC-Rno-105204	Rattus norvegicus	96.38	7.00e-161	559.00
IUUC-Sha-106579	Sarcophilus harrisii	85.94	6.00e-127	446.00
IUUC-Smo-109525	Selaginella moellendorffii	35.59	4.00e-42	164.00
IUUC-Sit-110072	Setaria italica	35.14	4.00e-41	161.00
IUUC-Sly-111473	Solanum lycopersicum	36.65	2.00e-46	179.00
IUUC-Stu-112353	Solanum tuberosum	36.20	2.00e-44	172.00
IUUC-Sbi-114250	Sorghum bicolor	36.59	1.00e-44	173.00
IUUC-Ssc-115416	Sus scrofa	95.71	3.00e-169	587.00
IUUC-Tgu-117272	Taeniopygia guttata	92.59	7.00e-57	211.00
IUUC-Tru-117777	Takifugu rubripes	78.60	3.00e-129	454.00
IUUC-Tni-120572	Tetraodon nigroviridis	79.30	3.00e-130	457.00
IUUC-Tca-121149	Theobroma cacao	38.04	3.00e-49	188.00
IUUC-Tre-122230	Trichoderma reesei	33.21	1.00e-32	132.00
IUUC-Tvi-122678	Trichoderma virens	35.61	2.00e-42	165.00
IUUC-Tae-124860	Triticum aestivum	35.14	3.00e-42	165.00
IUUC-Tur-126009	Triticum urartu	34.23	6.00e-38	150.00
IUUC-Tme-126948	Tuber melanosporum	35.59	5.00e-41	160.00
IUUC-Ttr-129031	Tursiops truncatus	93.40	2.00e-167	581.00
IUUC-Vda-130023	Verticillium dahliae	32.97	7.00e-40	157.00
IUUC-Vvi-131091	Vitis vinifera	49.44	1.00e-25	108.00
IUUC-Xtr-132871	Xenopus tropicalis	81.79	3.00e-129	454.00
IUUC-Xma-134220	Xiphophorus maculatus	77.54	1.00e-127	448.00
IUUC-Yli-134462	Yarrowia lipolytica	29.23	1.00e-28	120.00
IUUC-Zma-135773	Zea mays	37.05	6.00e-45	174.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence