iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Hvu-047538

Ensembl Protein ID

MLOC_55240.1

UniProt Accession

M0WWI0; M0WWI0_HORVV

Protein Name

Ubiquitinyl hydrolase 1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MLOC_55240	MLOC_55240.1	MLOC_55240.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.50e-52	180.0	447	1077

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgyeqqDaqE 94
           Gl+NlgNtCYmN++LQcL+++ elr  +l           p  + g++  +l++lf e    +++++a +p++ll+ ++ ++++f+g+  qD++E
   Q: 447  GLSNLGNTCYMNALLQCLLALGELRTTILG----------PGARLGSIGLHLKQLFVETSstNNSRRALEPKMLLEDMRVFNPQFRGSFMQDSEE 531
           9*****************************..........3456789*********99987799999**************************** PP
   S: 95   flaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke.... 185
           fl+ l ++leee                    +d ++ +   k + + + +F++ l++++ c +c ++s+++    +l+l++p+k+  + +    
   Q: 532  FLTSLCSALEEET-------------------DDLNKLHGGVKFPIIGDSIFGVWLRQTVCCISCSTESVSDMRIHELQLALPSKDCPARSvtlp 607
           *************...................556677788888899999************************************98888**** PP
   S: 186  ............................................................................................... 185
                                                                                                          
   Q: 608  pktrshgsptktrkelfqqtdktdgekiqtiaeggdsqfpgsefgdeamvktpkplqvdstevedvahgrlqtqkndfpleiievpikvldfipn 702
           *********************************************************************************************** PP
   S: 186  .................................................................slqdcLesftkeeelegenkyycekck... 212
                                                                            sl+dcL  f   + +e    ++c+kc    
   Q: 703  lfddtegmdesivdphspedtgppplvdieakenaysvelttedkgraqssditddeavrmnsvaSLEDCLTLFC-YCPVE----WKCDKCSevv 792
           *****************************************************************7777776654.55666....7777777777 PP
   S: 213  ............................................................................................... 212
                                                                                                          
   Q: 793  klprtngsengepmiastnvnptvegdrtelsdrktcpseqsndsnnlsvectspsrqphgsdaqnqvsisedriseeitsgmsydeknsascst 887
           77777777777777777777777777777777777777777777777777777777777777777777777777777777777777777777777 PP
   S: 213  ..........................................................kkqe.........aekklklkklPevLilhLkRfsfs 240
                                                                     +  +           ++  ++klP+vL+++LkRf   
   Q: 888  tnkkpeshegvqeaapssfptdkqtdllgtqdsqdtsdqnqgsgkqvklddhsaqqveE--NqmeqkhgtgGFQTQLVTKLPPVLTIQLKRF--- 977
           77888888888888888888887777777777777777777776666666666555550..05555566666777799**************... PP
   S: 241  eeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvkn..ekgk.......WllfdDskVtevkeeevlee 325
             ++  +k   +v+f++ L + pf+  ++ ++k + +Y+L++v+ H G  l+ GHYvayv+   +  +       W++ +D  ++ev+ +evl  
   Q: 978  --TNALSKTRGHVSFKEILHVGPFVDPSS-EDKGNSSYRLVGVIEHRGhALNVGHYVAYVRAgpK--QqssgsssWVHASDCAIKEVPLKEVLG- 1066
           ..67789******************9855.5567****************************651..33455677*******************. PP
   S: 326  tgstaYvlfYkrr 338
             ++aY+lfY+r+
   Q: 1067 --CEAYMLFYERM 1077
           ..*********96 PP

Organism

Hordeum vulgare

Protein Sequence
(Fasta)

MVEEKRERAE KASESPQKSP RLDPLAAPAA GPGCSATSAS PTESSEWPSY EEAEAATSSD 60
STVDSMDDSG RCRHILYDLE MVVQDLKVAN KVLKDPLRCE HRDCKTTWKG GGEDDQGMMK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTACGCACGG CCGCAACAGT TCCTCACCCA GCCCACCAAA CCTGCCCCGG CGCCAGCGAC 60
CAGCGAAACC GCCTCGCTGC TCCGCTCGGT TCTCCCTCCG ACTCCTCTTC CCTCGCCGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001048	Aegilops tauschii	80.73	0.00e+00	1713.00
IUUC-Bdi-014985	Brachypodium distachyon	54.02	0.00e+00	803.00
IUUC-Lpe-050943	Leersia perrieri	41.10	3.00e-146	511.00
IUUC-Oba-075758	Oryza barthii	40.19	5.00e-147	514.00
IUUC-Obr-076602	Oryza brachyantha	40.50	3.00e-146	511.00
IUUC-Ogl-077119	Oryza glaberrima	40.19	4.00e-147	514.00
IUUC-Ogu-078236	Oryza glumaepatula	39.59	6.00e-146	510.00
IUUC-Oin-079217	Oryza indica	39.95	3.00e-147	514.00
IUUC-Olo-080785	Oryza longistaminata	42.68	2.00e-153	535.00
IUUC-Ome-081726	Oryza meridionalis	40.74	7.00e-132	464.00
IUUC-Oni-082965	Oryza nivara	41.53	1.00e-148	519.00
IUUC-Opu-083353	Oryza punctata	41.29	1.00e-152	533.00
IUUC-Oru-085230	Oryza rufipogon	41.65	4.00e-149	520.00
IUUC-Osa-085674	Oryza sativa	39.95	4.00e-147	514.00
IUUC-Sit-110506	Setaria italica	35.12	7.00e-92	330.00
IUUC-Sbi-114695	Sorghum bicolor	34.92	2.00e-91	329.00
IUUC-Tae-125763	Triticum aestivum	84.36	0.00e+00	1809.00
IUUC-Tur-126231	Triticum urartu	84.86	0.00e+00	1780.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence