iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132430

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin-specific peptidase 39

Genbank Nucleotide ID

AAMC01014100

Gene Name

usp39

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000001269.3	ENSXETT00000002727.3	ENSXETP00000002727.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.70e-48	165.0	158	491

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaee.fsg 86
           +Gl+N+ +  Y N+vLQ+Lsn+p+lr+++le+++    ++ p +    l++ + +l+++lw   + k +vsp+e+l+a+  ++++ f+ 
   Q: 158  VGLNNIKANDYANAVLQALSNVPPLRNYFLEEENYCDIKRPPGDIMFLLVQRFGELMRKLWnpRNFKAHVSPHEMLQAVVLCSKKnFQI 246
           6******************************6666556677788899**************999999**************99999*** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlk................sqikclec 159
           ++q D  +fl+++l++l+++l                       ++kkk     +++d+Fqg+++                +q++ +e 
   Q: 247  TKQGDGVDFLSWFLNALNSALG---------------------GNKKKKIFLLAIVTDVFQGSMRiftkklphpdlpseekEQLMQNEE 314
           *********************2.....................23455666668888888888888888888888888888******** PP
   S: 160  dnvssreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckk.kqeaekklklkklPevLilhLkRfsfseeqksre 247
            +++  e+pf++l+l++p     k e+ q ++ +      l + n +  ++ k  k +  k+++l++lP++Li+ +kRf  ++++ + e
   Q: 315  YQEKMLESPFMYLTLDLPTAPLYKDEKEQLIIPQVPLFSILGKFNGITEKEYKTyKENFLKRFQLTQLPPFLIFCIKRF--TKNNFFVE 401
           ******************888777775555555555555554444444444433134589*******************..88889*** PP
   S: 248  kinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetgstaYvlf 334
           k+ + v+fp++ +dl+++++++ ++++++++Y+Lia vvH G++++G Y  +v +  +gkW+++ D +Vt +  + +     s+aY+ +
   Q: 402  KNPTIVNFPITnVDLREYLAEEFQSSHKNTTYDLIANVVHDGKPNEGSYRIHVLHhGTGKWYELQDLQVTDILPQMITL---SEAYIQI 487
           *****************************************************9935666******************9...******* PP
   S: 335  Ykrr 338
           +krr
   Q: 488  WKRR 491
           *985 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

VKLEMEEEDD DDDDDERVVG KHGRYDFEDR RSRHCPYLDT INRSVLDFDF EKLCSISLSH 60
INAYACLVCG KYFQAPQGRG LKSHAYIHSV QFSHHVFLNL HTLKFYCLPD NYNIIDSSLE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGAAACTGG AGATGGAGGA GGAAGACGAC GACGATGATG ATGATGAGAG AGGTGAGGGA 60
AACTCATTCT ATTGATGCGA CTTGGTGTGA ATAGTGTAAC GGATTGATTG AGTAAAAGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR033809--USP39
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH
PF02148--zf-UBP

SMART

SM00290--ZnF_UBP

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0048855--P:adenohypophysis morphogenesis
GO:0016579--P:protein deubiquitination
GO:0043484--P:regulation of RNA splicing
GO:0000245--P:spliceosomal complex assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000483	Aegilops tauschii	51.37	7.00e-124	437.00
IUUC-Aml-001846	Ailuropoda melanoleuca	91.55	0.00e+00	906.00
IUUC-Atr-002758	Amborella trichopoda	48.76	3.00e-125	441.00
IUUC-Apl-003336	Anas platyrhynchos	83.73	2.00e-164	571.00
IUUC-Aca-004846	Anolis carolinensis	91.97	0.00e+00	863.00
IUUC-Aly-005683	Arabidopsis lyrata	49.48	2.00e-113	402.00
IUUC-Ath-007652	Arabidopsis thaliana	48.64	6.00e-111	394.00
IUUC-Ago-007802	Ashbya gossypii	30.41	3.00e-56	212.00
IUUC-Acl-008304	Aspergillus clavatus	40.78	4.00e-92	332.00
IUUC-Afl-008735	Aspergillus flavus	55.83	8.00e-38	151.00
IUUC-Afu-009100	Aspergillus fumigatus	40.59	2.00e-89	322.00
IUUC-Ani-009138	Aspergillus nidulans	48.05	4.00e-93	335.00
IUUC-Ang-009661	Aspergillus niger	44.33	1.00e-94	340.00
IUUC-Aor-010235	Aspergillus oryzae	38.34	6.00e-80	291.00
IUUC-Ate-010346	Aspergillus terreus	36.36	7.00e-73	268.00
IUUC-Ame-011688	Astyanax mexicanus	86.85	0.00e+00	838.00
IUUC-Bgr-011998	Blumeria graminis	46.45	7.00e-113	400.00
IUUC-Bta-013407	Bos taurus	91.34	0.00e+00	901.00
IUUC-Bci-013977	Botrytis cinerea	47.31	2.00e-112	399.00
IUUC-Bdi-014361	Brachypodium distachyon	51.60	3.00e-129	455.00
IUUC-Bol-016317	Brassica oleracea	48.54	1.00e-111	396.00
IUUC-Bra-017952	Brassica rapa	49.06	5.00e-113	401.00
IUUC-Cel-018491	Caenorhabditis elegans	61.33	3.00e-178	618.00
IUUC-Cja-019134	Callithrix jacchus	91.34	0.00e+00	903.00
IUUC-Cfa-020098	Canis familiaris	91.34	0.00e+00	902.00
IUUC-Cpo-021595	Cavia porcellus	91.34	0.00e+00	900.00
IUUC-Cre-022886	Chlamydomonas reinhardtii	50.00	9.00e-31	124.00
IUUC-Csa-024121	Chlorocebus sabaeus	91.34	0.00e+00	902.00
IUUC-Cho-025057	Choloepus hoffmanni	73.79	3.00e-81	295.00
IUUC-Cin-025473	Ciona intestinalis	62.67	1.00e-65	241.00
IUUC-Csv-025815	Ciona savignyi	61.18	3.00e-178	617.00
IUUC-Cgl-026416	Colletotrichum gloeosporioides	42.95	1.00e-106	380.00
IUUC-Cne-026802	Cryptococcus neoformans	42.80	3.00e-100	358.00
IUUC-Dre-027870	Danio rerio	86.49	0.00e+00	826.00
IUUC-Dno-029655	Dasypus novemcinctus	89.90	0.00e+00	899.00
IUUC-Dor-030762	Dipodomys ordii	91.34	0.00e+00	900.00
IUUC-Dse-031441	Dothistroma septosporum	43.40	8.00e-107	380.00
IUUC-Dme-032101	Drosophila melanogaster	63.85	6.00e-177	613.00
IUUC-Ete-032841	Echinops telfairi	86.39	0.00e+00	857.00
IUUC-Eca-033463	Equus caballus	91.34	0.00e+00	900.00
IUUC-Eeu-034438	Erinaceus europaeus	66.39	3.00e-177	614.00
IUUC-Fca-035774	Felis catus	91.34	0.00e+00	903.00
IUUC-Fal-036988	Ficedula albicollis	89.00	0.00e+00	892.00
IUUC-Fox-037895	Fusarium oxysporum	44.68	2.00e-104	372.00
IUUC-Fso-038450	Fusarium solani	44.89	6.00e-105	374.00
IUUC-Gmo-038874	Gadus morhua	85.74	0.00e+00	813.00
IUUC-Ggr-040115	Gaeumannomyces graminis	42.98	4.00e-100	358.00
IUUC-Gac-041650	Gasterosteus aculeatus	86.14	0.00e+00	835.00
IUUC-Gma-043697	Glycine max	48.53	2.00e-124	439.00
IUUC-Ggo-044707	Gorilla gorilla	84.54	0.00e+00	821.00
IUUC-Hsa-046041	Homo sapiens	91.34	0.00e+00	901.00
IUUC-Hvu-047816	Hordeum vulgare	49.79	7.00e-117	414.00
IUUC-Itr-048945	Ictidomys tridecemlineatus	91.30	0.00e+00	635.00
IUUC-Lch-050419	Latimeria chalumnae	88.27	0.00e+00	883.00
IUUC-Lpe-051593	Leersia perrieri	52.25	1.00e-129	456.00
IUUC-Loc-052930	Lepisosteus oculatus	86.24	0.00e+00	844.00
IUUC-Lma-053256	Leptosphaeria maculans	45.30	7.00e-110	390.00
IUUC-Laf-053555	Loxodonta africana	91.13	0.00e+00	896.00
IUUC-Mcc-055630	Macaca mulatta	91.34	0.00e+00	902.00
IUUC-Meu-056579	Macropus eugenii	85.67	1.00e-165	575.00
IUUC-Mor-057078	Magnaporthe oryzae	42.98	2.00e-102	366.00
IUUC-Mpo-057607	Magnaporthe poae	37.09	2.00e-81	296.00
IUUC-Mtr-058644	Medicago truncatula	47.89	5.00e-123	434.00
IUUC-Mla-059120	Melampsora laricipopulina	41.95	6.00e-98	351.00
IUUC-Mvi-060429	Microbotryum violaceum	45.75	3.00e-68	252.00
IUUC-Mmr-061313	Microcebus murinus	91.34	0.00e+00	901.00
IUUC-Mdo-062801	Monodelphis domestica	90.46	0.00e+00	900.00
IUUC-Mmu-064424	Mus musculus	91.13	0.00e+00	915.00
IUUC-Mac-064694	Musa acuminata	49.05	3.00e-124	438.00
IUUC-Mpu-065980	Mustela putorius furo	91.80	0.00e+00	798.00
IUUC-Mlu-067007	Myotis lucifugus	90.31	0.00e+00	902.00
IUUC-Nfi-068274	Neosartorya fischeri	40.59	2.00e-89	323.00
IUUC-Ncr-068829	Neurospora crassa	46.25	3.00e-106	379.00
IUUC-Nle-069171	Nomascus leucogenys	91.51	0.00e+00	898.00
IUUC-Opr-070494	Ochotona princeps	82.27	0.00e+00	804.00
IUUC-Ont-072290	Oreochromis niloticus	85.03	0.00e+00	853.00
IUUC-Oan-073099	Ornithorhynchus anatinus	90.93	0.00e+00	894.00
IUUC-Ocu-074642	Oryctolagus cuniculus	91.34	0.00e+00	901.00
IUUC-Oba-075886	Oryza barthii	52.25	1.00e-129	456.00
IUUC-Obr-076220	Oryza brachyantha	51.39	7.00e-129	454.00
IUUC-Ogl-077682	Oryza glaberrima	52.25	1.00e-129	456.00
IUUC-Ogu-078492	Oryza glumaepatula	52.03	3.00e-129	455.00
IUUC-Oin-079956	Oryza indica	52.25	1.00e-129	456.00
IUUC-Olo-080239	Oryza longistaminata	45.93	8.00e-101	362.00
IUUC-Ome-081573	Oryza meridionalis	52.25	4.00e-130	457.00
IUUC-Oni-082975	Oryza nivara	52.25	1.00e-129	456.00
IUUC-Opu-083724	Oryza punctata	51.82	3.00e-129	455.00
IUUC-Oru-084566	Oryza rufipogon	52.25	1.00e-129	456.00
IUUC-Osa-086008	Oryza sativa	52.25	8.00e-130	457.00
IUUC-Ola-086967	Oryzias latipes	88.02	0.00e+00	843.00
IUUC-Olu-087614	Ostreococcus lucimarinus	42.92	2.00e-96	345.00
IUUC-Oga-088047	Otolemur garnettii	75.26	1.00e-163	569.00
IUUC-Oar-089393	Ovis aries	91.34	0.00e+00	902.00
IUUC-Ptr-090561	Pan troglodytes	91.34	0.00e+00	902.00
IUUC-Pan-091812	Papio anubis	91.34	0.00e+00	902.00
IUUC-Psi-093507	Pelodiscus sinensis	90.67	1.00e-157	548.00
IUUC-Pno-095104	Phaeosphaeria nodorum	44.98	1.00e-108	387.00
IUUC-Ppa-095995	Physcomitrella patens	50.42	3.00e-129	454.00
IUUC-Pfo-096754	Poecilia formosa	85.47	0.00e+00	848.00
IUUC-Pab-098053	Pongo abelii	91.34	0.00e+00	902.00
IUUC-Pop-099230	Populus trichocarpa	50.42	1.00e-129	456.00
IUUC-Pca-100407	Procavia capensis	82.68	0.00e+00	801.00
IUUC-Ppe-101699	Prunus persica	50.43	6.00e-124	437.00
IUUC-Pva-103159	Pteropus vampyrus	87.63	0.00e+00	855.00
IUUC-Pgr-103433	Puccinia graminis	42.36	1.00e-101	363.00
IUUC-Ptt-103701	Puccinia triticina	39.40	7.00e-91	327.00
IUUC-Pte-104281	Pyrenophora teres	45.06	2.00e-108	385.00
IUUC-Pyt-104714	Pyrenophora triticirepentis	45.06	4.00e-108	385.00
IUUC-Rno-105531	Rattus norvegicus	91.34	0.00e+00	918.00
IUUC-Sce-106368	Saccharomyces cerevisiae	30.74	4.00e-46	178.00
IUUC-Sha-107093	Sarcophilus harrisii	90.66	0.00e+00	897.00
IUUC-Sja-108004	Schizosaccharomyces japonicus	43.84	1.00e-115	409.00
IUUC-Spo-108018	Schizosaccharomyces pombe	46.09	1.00e-112	400.00
IUUC-Ssl-108460	Sclerotinia sclerotiorum	44.87	2.00e-105	375.00
IUUC-Smo-108892	Selaginella moellendorffii	51.41	1.00e-127	449.00
IUUC-Sit-110782	Setaria italica	52.65	3.00e-131	461.00
IUUC-Sly-111308	Solanum lycopersicum	51.30	4.00e-133	468.00
IUUC-Stu-112447	Solanum tuberosum	51.52	2.00e-133	469.00
IUUC-Sar-113352	Sorex araneus	83.96	0.00e+00	723.00
IUUC-Sbi-114806	Sorghum bicolor	51.67	2.00e-130	459.00
IUUC-Sre-115059	Sporisorium reilianum	39.42	2.00e-89	323.00
IUUC-Ssc-115677	Sus scrofa	90.20	0.00e+00	632.00
IUUC-Tru-118478	Takifugu rubripes	85.02	0.00e+00	841.00
IUUC-Tsy-119082	Tarsius syrichta	79.72	0.00e+00	679.00
IUUC-Tni-120419	Tetraodon nigroviridis	84.42	0.00e+00	826.00
IUUC-Tca-121294	Theobroma cacao	49.68	2.00e-130	459.00
IUUC-Tre-121962	Trichoderma reesei	44.89	4.00e-99	355.00
IUUC-Tvi-122280	Trichoderma virens	44.56	2.00e-106	379.00
IUUC-Tae-125873	Triticum aestivum	52.67	6.00e-130	457.00
IUUC-Tur-126551	Triticum urartu	52.67	8.00e-130	456.00
IUUC-Tme-126959	Tuber melanosporum	46.51	5.00e-113	401.00
IUUC-Tbe-127737	Tupaia belangeri	91.94	0.00e+00	855.00
IUUC-Ttr-129211	Tursiops truncatus	94.05	3.00e-141	495.00
IUUC-Uma-129591	Ustilago maydis	39.50	2.00e-94	340.00
IUUC-Vda-129674	Verticillium dahliae	42.55	4.00e-92	331.00
IUUC-Vpa-130793	Vicugna pacos	85.40	0.00e+00	789.00
IUUC-Xma-133515	Xiphophorus maculatus	85.07	0.00e+00	835.00
IUUC-Yli-134488	Yarrowia lipolytica	36.60	7.00e-76	277.00
IUUC-Zma-134748	Zea mays	52.97	1.00e-130	459.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence