iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-098392

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

E3 ubiquitin-protein ligase RING2

Genbank Nucleotide ID

ABGA01049657

Gene Name

RNF2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000000417.2	ENSPPYT00000000493.2	ENSPPYP00000000473.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.80e-07	31.7	51	91

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iCl+++k+   +  C H f+adC+  ++       s++  CP+Cr
   Q: 51   CPICLDMLKNTMTTKECLHRFCADCIiTAL------RSGNKECPTCR 91
           **********555555*********98888......**********8 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MSQAVQTNGT QPLFKTWELT LYDLQRTPQE AITDGLEIVV SPRSLHSELM CPICLDMLKN 60
TMTTKECLHR FCADCIITAL RSGNKECPTC RKKLVSKRSL RPDPNFDALI SKIYPSRDEY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCAGCCCAG GGCGGGGCGG TGGCTCGGGT TCTCCAGGCC AACACGCGGC GGCGCACCCT 60
CCCCTCGCGC CGCGGGCCTT CCCGCGCCGT GCACGTCCTC GTCCCGCGCC TCCGCCCCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032443--RAWUL
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF16207--RAWUL

SMART

SM00184--RING

Gene Ontology

GO:0000791--C:euchromatin
GO:0071339--C:MLL1 complex
GO:0016604--C:nuclear body
GO:0035102--C:PRC1 complex
GO:0001739--C:sex chromatin
GO:0003682--F:chromatin binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0009948--P:anterior/posterior axis specification
GO:0001702--P:gastrulation with mouth forming second
GO:0007281--P:germ cell development
GO:0036353--P:histone H2A-K119 monoubiquitination
GO:0000278--P:mitotic cell cycle
GO:0043433--P:negative regulation of sequence-specific DNA binding transcription factor activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000516	Aegilops tauschii	57.81	7.00e-19	88.20
IUUC-Aml-001250	Ailuropoda melanoleuca	98.20	0.00e+00	687.00
IUUC-Apl-003587	Anas platyrhynchos	97.32	0.00e+00	688.00
IUUC-Aca-004928	Anolis carolinensis	96.73	0.00e+00	686.00
IUUC-Aly-005911	Arabidopsis lyrata	50.00	9.00e-23	101.00
IUUC-Ath-006899	Arabidopsis thaliana	48.28	6.00e-23	101.00
IUUC-Ame-010622	Astyanax mexicanus	88.39	0.00e+00	629.00
IUUC-Bta-013553	Bos taurus	98.51	0.00e+00	696.00
IUUC-Bdi-014202	Brachypodium distachyon	55.42	2.00e-24	107.00
IUUC-Bol-015993	Brassica oleracea	48.94	7.00e-24	105.00
IUUC-Bra-017150	Brassica rapa	48.04	6.00e-24	105.00
IUUC-Cja-019093	Callithrix jacchus	98.81	0.00e+00	697.00
IUUC-Cfa-020681	Canis familiaris	98.22	0.00e+00	692.00
IUUC-Cpo-021402	Cavia porcellus	83.33	3.00e-160	557.00
IUUC-Cre-022709	Chlamydomonas reinhardtii	35.48	4.00e-07	49.70
IUUC-Csa-024231	Chlorocebus sabaeus	99.11	0.00e+00	699.00
IUUC-Cho-024843	Choloepus hoffmanni	83.33	1.00e-161	561.00
IUUC-Csv-026314	Ciona savignyi	46.93	9.00e-83	300.00
IUUC-Dre-027685	Danio rerio	88.39	0.00e+00	628.00
IUUC-Dno-029993	Dasypus novemcinctus	97.62	0.00e+00	691.00
IUUC-Dor-030986	Dipodomys ordii	70.54	3.00e-131	461.00
IUUC-Dme-031721	Drosophila melanogaster	78.08	5.00e-67	248.00
IUUC-Ete-032564	Echinops telfairi	81.25	4.00e-159	553.00
IUUC-Eca-033251	Equus caballus	98.51	0.00e+00	696.00
IUUC-Eeu-034951	Erinaceus europaeus	98.51	0.00e+00	696.00
IUUC-Fca-036240	Felis catus	98.21	0.00e+00	689.00
IUUC-Fal-037376	Ficedula albicollis	97.02	0.00e+00	686.00
IUUC-Gmo-038879	Gadus morhua	84.66	1.00e-164	572.00
IUUC-Gga-041134	Gallus gallus	97.02	0.00e+00	686.00
IUUC-Gac-042589	Gasterosteus aculeatus	85.00	2.00e-166	577.00
IUUC-Gma-044386	Glycine max	33.77	2.00e-23	103.00
IUUC-Ggo-044529	Gorilla gorilla	99.11	0.00e+00	699.00
IUUC-Hsa-046100	Homo sapiens	99.11	0.00e+00	699.00
IUUC-Hvu-047152	Hordeum vulgare	54.22	5.00e-24	105.00
IUUC-Itr-047891	Ictidomys tridecemlineatus	98.21	0.00e+00	694.00
IUUC-Lch-049494	Latimeria chalumnae	88.99	3.00e-176	610.00
IUUC-Lpe-050923	Leersia perrieri	44.35	5.00e-25	108.00
IUUC-Loc-052544	Lepisosteus oculatus	87.43	3.00e-180	624.00
IUUC-Laf-053675	Loxodonta africana	99.03	0.00e+00	635.00
IUUC-Mcc-055685	Macaca mulatta	99.11	0.00e+00	698.00
IUUC-Mtr-058234	Medicago truncatula	50.60	9.00e-24	104.00
IUUC-Mga-059354	Meleagris gallopavo	97.32	0.00e+00	688.00
IUUC-Mmr-060809	Microcebus murinus	98.81	0.00e+00	697.00
IUUC-Mdo-062206	Monodelphis domestica	97.92	0.00e+00	693.00
IUUC-Mmu-063715	Mus musculus	98.81	0.00e+00	697.00
IUUC-Mpu-066460	Mustela putorius furo	98.51	0.00e+00	696.00
IUUC-Mlu-067743	Myotis lucifugus	98.51	0.00e+00	696.00
IUUC-Nle-069512	Nomascus leucogenys	99.11	0.00e+00	699.00
IUUC-Opr-070807	Ochotona princeps	98.90	1.00e-105	375.00
IUUC-Ont-072541	Oreochromis niloticus	85.38	2.00e-168	584.00
IUUC-Oan-073454	Ornithorhynchus anatinus	97.92	0.00e+00	692.00
IUUC-Ocu-073981	Oryctolagus cuniculus	98.21	0.00e+00	695.00
IUUC-Oba-075605	Oryza barthii	53.01	1.00e-23	104.00
IUUC-Obr-076282	Oryza brachyantha	44.35	4.00e-25	109.00
IUUC-Ogl-077288	Oryza glaberrima	43.48	8.00e-25	108.00
IUUC-Ogu-078992	Oryza glumaepatula	53.01	1.00e-23	104.00
IUUC-Oin-079939	Oryza indica	43.48	7.00e-25	108.00
IUUC-Olo-080262	Oryza longistaminata	45.22	2.00e-25	110.00
IUUC-Ome-081418	Oryza meridionalis	44.35	4.00e-25	108.00
IUUC-Oni-083103	Oryza nivara	43.48	9.00e-25	108.00
IUUC-Opu-083314	Oryza punctata	44.35	7.00e-25	108.00
IUUC-Oru-084356	Oryza rufipogon	51.81	2.00e-23	103.00
IUUC-Osa-085727	Oryza sativa	43.48	7.00e-25	108.00
IUUC-Ola-086937	Oryzias latipes	86.35	4.00e-168	583.00
IUUC-Oga-089078	Otolemur garnettii	83.33	8.00e-118	415.00
IUUC-Oar-089823	Ovis aries	98.51	0.00e+00	695.00
IUUC-Ptr-090557	Pan troglodytes	99.11	0.00e+00	699.00
IUUC-Pan-091950	Papio anubis	99.11	0.00e+00	699.00
IUUC-Psi-093349	Pelodiscus sinensis	97.02	0.00e+00	687.00
IUUC-Ppa-095164	Physcomitrella patens	58.21	7.00e-22	98.20
IUUC-Pfo-096803	Poecilia formosa	85.09	7.00e-167	579.00
IUUC-Pop-100011	Populus trichocarpa	50.52	4.00e-25	108.00
IUUC-Pca-100946	Procavia capensis	98.81	3.00e-150	523.00
IUUC-Ppe-101894	Prunus persica	61.82	2.00e-17	82.80
IUUC-Pva-102498	Pteropus vampyrus	97.01	3.00e-76	278.00
IUUC-Rno-105492	Rattus norvegicus	98.81	0.00e+00	697.00
IUUC-Sha-107645	Sarcophilus harrisii	97.62	0.00e+00	691.00
IUUC-Sit-109707	Setaria italica	44.35	2.00e-25	110.00
IUUC-Sly-111537	Solanum lycopersicum	54.41	4.00e-19	89.40
IUUC-Sar-113064	Sorex araneus	97.62	4.00e-72	264.00
IUUC-Sbi-114798	Sorghum bicolor	43.48	2.00e-24	107.00
IUUC-Ssc-115830	Sus scrofa	98.51	0.00e+00	695.00
IUUC-Tgu-116694	Taeniopygia guttata	97.62	0.00e+00	691.00
IUUC-Tru-117837	Takifugu rubripes	84.80	5.00e-166	576.00
IUUC-Tsy-119174	Tarsius syrichta	97.02	0.00e+00	681.00
IUUC-Tni-120389	Tetraodon nigroviridis	84.84	3.00e-165	574.00
IUUC-Tca-121428	Theobroma cacao	32.69	1.00e-24	107.00
IUUC-Tae-125498	Triticum aestivum	54.22	4.00e-24	105.00
IUUC-Tur-126796	Triticum urartu	54.22	5.00e-24	105.00
IUUC-Tbe-127428	Tupaia belangeri	98.90	1.00e-105	374.00
IUUC-Ttr-128796	Tursiops truncatus	98.21	0.00e+00	694.00
IUUC-Vpa-130691	Vicugna pacos	98.51	0.00e+00	696.00
IUUC-Vvi-131143	Vitis vinifera	41.67	7.00e-25	108.00
IUUC-Xtr-132022	Xenopus tropicalis	92.86	0.00e+00	660.00
IUUC-Xma-133424	Xiphophorus maculatus	84.80	5.00e-167	580.00
IUUC-Yli-134563	Yarrowia lipolytica	41.07	8.00e-07	47.40

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence