iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004636

UUCD1 version

UUC-AnC-00639

Ensembl Protein ID

ENSACAP00000005007.3

UniProt Accession

G1KDM3; G1KDM3_ANOCA

Protein Name

Uncharacterized protein

Gene Name

TRAF6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000005108.3	ENSACAT00000005120.3	ENSACAP00000005007.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	2.40e-07	30.7	69	130

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrli 65
           + + CpI l   r+ v +p+G+ + +++I k +++ g++cP++++ l e++l P ++ +r i
   Q: 69   SKYECPICLMALREAVQTPCGHRFCKACIVKSIRDAGHKCPIDNEILLETQLFPDNFAKREI 130
           5689*****************************999999*****************999977 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MSLLHSNTSF ETNSQESGCC AAMASACSAA AKEESINASV SNETGGTLSN SFMEETQGYD 60
VEFDPPLESK YECPICLMAL REAVQTPCGH RFCKACIVKS IRDAGHKCPI DNEILLETQL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAACGGTCCG AAGGATCGTG AACTGGCCCC CTGTTTAAAA AGTTTGGGGA CCCCTGGTCT 60
ATGCCATACA GACCTACCAA AATCTATAGA CACCCGCCCC CTCCCTGTTG TTAGGAATTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027139--TRAF6
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF02176--zf-TRAF

SMART

SM00061--MATH
SM00184--RING

Gene Ontology

GO:0035631--C:CD40 receptor complex
GO:0009898--C:cytoplasmic side of plasma membrane
GO:0005829--C:cytosol
GO:0005811--C:lipid particle
GO:0005634--C:nucleus
GO:0048471--C:perinuclear region of cytoplasm
GO:0043234--C:protein complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007250--P:activation of NF-kappaB-inducing kinase activity
GO:0019886--P:antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0045453--P:bone resorption
GO:0048468--P:cell development
GO:0071222--P:cellular response to lipopolysaccharide
GO:0007249--P:I-kappaB kinase/NF-kappaB signaling
GO:0070498--P:interleukin-1-mediated signaling pathway
GO:0043011--P:myeloid dendritic cell differentiation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0001843--P:neural tube closure
GO:0042475--P:odontogenesis of dentin-containing tooth
GO:0001503--P:ossification
GO:0030316--P:osteoclast differentiation
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045084--P:positive regulation of interleukin-12 biosynthetic process
GO:0032743--P:positive regulation of interleukin-2 production
GO:0045410--P:positive regulation of interleukin-6 biosynthetic process
GO:0043507--P:positive regulation of JUN kinase activity
GO:0031666--P:positive regulation of lipopolysaccharide-mediated signaling pathway
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0045672--P:positive regulation of osteoclast differentiation
GO:0002726--P:positive regulation of T cell cytokine production
GO:0042102--P:positive regulation of T cell proliferation
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:2000679--P:positive regulation of transcription regulatory region DNA binding
GO:0051865--P:protein autoubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0042981--P:regulation of apoptotic process
GO:0051023--P:regulation of immunoglobulin secretion
GO:0050852--P:T cell receptor signaling pathway
GO:0042088--P:T-helper 1 type immune response

KEGG

acs:100561211

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000797	Aegilops tauschii	30.70	1.00e-07	50.40
IUUC-Aml-001262	Ailuropoda melanoleuca	73.96	0.00e+00	759.00
IUUC-Apl-004062	Anas platyrhynchos	76.17	0.00e+00	840.00
IUUC-Ame-011682	Astyanax mexicanus	54.29	1.00e-165	576.00
IUUC-Bta-012692	Bos taurus	71.24	0.00e+00	765.00
IUUC-Bci-013998	Botrytis cinerea	23.65	9.00e-12	64.70
IUUC-Cja-019426	Callithrix jacchus	70.26	0.00e+00	756.00
IUUC-Cfa-020948	Canis familiaris	72.25	0.00e+00	673.00
IUUC-Cpo-021378	Cavia porcellus	72.89	0.00e+00	748.00
IUUC-Csa-024045	Chlorocebus sabaeus	70.44	0.00e+00	768.00
IUUC-Cho-024973	Choloepus hoffmanni	62.79	3.00e-75	275.00
IUUC-Csv-026300	Ciona savignyi	41.18	2.00e-44	171.00
IUUC-Dre-027557	Danio rerio	58.22	1.00e-175	609.00
IUUC-Dno-030032	Dasypus novemcinctus	73.40	6.00e-114	403.00
IUUC-Dor-030790	Dipodomys ordii	71.57	0.00e+00	762.00
IUUC-Dme-031921	Drosophila melanogaster	34.00	3.00e-22	99.80
IUUC-Ete-032952	Echinops telfairi	68.22	2.00e-138	485.00
IUUC-Eca-033924	Equus caballus	68.44	0.00e+00	679.00
IUUC-Eeu-034734	Erinaceus europaeus	64.60	0.00e+00	660.00
IUUC-Fca-036222	Felis catus	68.97	0.00e+00	686.00
IUUC-Fal-036834	Ficedula albicollis	78.13	0.00e+00	779.00
IUUC-Fox-037935	Fusarium oxysporum	30.52	2.00e-21	96.70
IUUC-Gmo-039061	Gadus morhua	63.09	3.00e-86	312.00
IUUC-Ggr-040084	Gaeumannomyces graminis	27.67	2.00e-13	70.90
IUUC-Gga-040599	Gallus gallus	76.82	0.00e+00	846.00
IUUC-Gac-041977	Gasterosteus aculeatus	53.54	6.00e-162	563.00
IUUC-Ggo-044508	Gorilla gorilla	66.67	0.00e+00	699.00
IUUC-Hsa-046349	Homo sapiens	70.80	0.00e+00	774.00
IUUC-Itr-047966	Ictidomys tridecemlineatus	74.45	0.00e+00	766.00
IUUC-Lch-049821	Latimeria chalumnae	67.98	0.00e+00	752.00
IUUC-Loc-051995	Lepisosteus oculatus	61.49	2.00e-180	625.00
IUUC-Laf-054115	Loxodonta africana	69.16	0.00e+00	750.00
IUUC-Mcc-055298	Macaca mulatta	70.44	0.00e+00	768.00
IUUC-Mor-057263	Magnaporthe oryzae	30.45	4.00e-20	92.40
IUUC-Mpo-057517	Magnaporthe poae	29.46	4.00e-16	79.70
IUUC-Mga-059340	Meleagris gallopavo	77.19	0.00e+00	847.00
IUUC-Mvi-060553	Microbotryum violaceum	27.68	7.00e-16	78.60
IUUC-Mmr-061063	Microcebus murinus	74.49	0.00e+00	772.00
IUUC-Mdo-062075	Monodelphis domestica	69.91	0.00e+00	763.00
IUUC-Mmu-063780	Mus musculus	73.44	0.00e+00	757.00
IUUC-Mpu-065748	Mustela putorius furo	71.58	0.00e+00	769.00
IUUC-Mlu-067888	Myotis lucifugus	71.85	0.00e+00	758.00
IUUC-Ncr-068632	Neurospora crassa	28.29	1.00e-16	81.30
IUUC-Nle-069234	Nomascus leucogenys	70.44	0.00e+00	768.00
IUUC-Opr-070393	Ochotona princeps	75.12	1.00e-96	346.00
IUUC-Ont-072459	Oreochromis niloticus	53.90	1.00e-169	589.00
IUUC-Oan-073578	Ornithorhynchus anatinus	72.63	0.00e+00	794.00
IUUC-Ocu-074201	Oryctolagus cuniculus	73.86	0.00e+00	766.00
IUUC-Oba-075263	Oryza barthii	28.66	3.00e-09	55.80
IUUC-Ogl-077708	Oryza glaberrima	29.01	8.00e-09	54.30
IUUC-Ogu-078582	Oryza glumaepatula	28.66	3.00e-09	55.80
IUUC-Oin-079499	Oryza indica	29.01	3.00e-09	55.80
IUUC-Ome-081269	Oryza meridionalis	28.66	2.00e-09	56.60
IUUC-Oni-083040	Oryza nivara	33.33	1.00e-06	46.60
IUUC-Opu-083468	Oryza punctata	30.43	7.00e-08	51.20
IUUC-Oru-084662	Oryza rufipogon	28.66	1.00e-08	54.30
IUUC-Osa-085740	Oryza sativa	33.33	2.00e-06	46.20
IUUC-Ola-087319	Oryzias latipes	60.32	5.00e-88	318.00
IUUC-Olu-087748	Ostreococcus lucimarinus	22.46	8.00e-08	51.20
IUUC-Oga-087936	Otolemur garnettii	71.88	0.00e+00	755.00
IUUC-Oar-089379	Ovis aries	70.49	0.00e+00	774.00
IUUC-Ptr-090758	Pan troglodytes	70.80	0.00e+00	769.00
IUUC-Pan-092590	Papio anubis	70.62	0.00e+00	769.00
IUUC-Psi-093948	Pelodiscus sinensis	77.55	0.00e+00	866.00
IUUC-Pma-094434	Petromyzon marinus	44.24	1.00e-122	432.00
IUUC-Pfo-096912	Poecilia formosa	54.34	5.00e-162	564.00
IUUC-Pab-097651	Pongo abelii	70.80	0.00e+00	771.00
IUUC-Pca-100958	Procavia capensis	69.44	2.00e-163	567.00
IUUC-Pva-103247	Pteropus vampyrus	74.90	4.00e-102	365.00
IUUC-Pte-104279	Pyrenophora teres	26.64	1.00e-12	68.20
IUUC-Rno-104994	Rattus norvegicus	72.53	0.00e+00	774.00
IUUC-Sha-106494	Sarcophilus harrisii	72.26	0.00e+00	778.00
IUUC-Sar-113375	Sorex araneus	72.73	0.00e+00	754.00
IUUC-Sre-115218	Sporisorium reilianum	26.85	6.00e-17	82.40
IUUC-Ssc-115417	Sus scrofa	74.55	0.00e+00	771.00
IUUC-Tgu-117232	Taeniopygia guttata	79.12	0.00e+00	831.00
IUUC-Tru-118321	Takifugu rubripes	55.66	3.00e-167	581.00
IUUC-Tni-120475	Tetraodon nigroviridis	55.34	3.00e-162	564.00
IUUC-Tbe-127719	Tupaia belangeri	62.18	0.00e+00	635.00
IUUC-Ttr-129264	Tursiops truncatus	79.72	8.00e-100	357.00
IUUC-Uma-129620	Ustilago maydis	26.38	3.00e-17	83.60
IUUC-Vpa-130244	Vicugna pacos	75.00	9.00e-104	370.00
IUUC-Xtr-131948	Xenopus tropicalis	65.36	0.00e+00	725.00
IUUC-Xma-133132	Xiphophorus maculatus	53.58	1.00e-164	572.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence