iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFAC
Protein-protein Interaction
Mentha
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 activity/RING/RING	RING	15998807

Classification

Family	E-value	Score	Start	End
E3 activity/RING/RING	3.20e-05	25.2	230	271

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf...kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iC+e +   ++    lpC+H+fh  Cl+ w         + +CP+Cr
   Q: 230  CCICKENLvigDK-MQELPCKHTFHPPCLKPW------LDEHNSCPICR 271
           ******9988544.778***************......**********8 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

E3 ubiquitin-protein ligase that acts as a negative regulator of abscisic acid (ABA) signaling. Mediates ubiquitination and subsequent proteasomal degradation of the transcription factor ABI3.

Protein Sequence
(Fasta)

MDASSSPSPS EESLKLELDD LQKQLNKKLR FEASVCSIHN LLRDHYSSSS PSLRKQFYIV 60
VSRVATVLKT RYTATGFWVA GLSLFEEAER LVSDASEKKH LKSCVAQAKE QLSEVDNQPT 120

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Nucleotide Sequence
(Fasta)

GAACCGAACC AAACCGAACT GAACTATATT AACCGACCGA CTTCGTCCTT TCCTCCTGAT 60
CAAGAAAACT CGTCTCCTAC AAAAATCCCA GAAGACAAGA GATTGGTTCT TCTTTTGCAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0938--Abscisic acid signaling pathway
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0808--Transferase
KW-0832--Ubl conjugation
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0061630--F:ubiquitin protein ligase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0009738--P:abscisic acid-activated signaling pathway
GO:0009788--P:negative regulation of abscisic acid-activated signaling pathway
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0016567--P:protein ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0009737--P:response to abscisic acid

KEGG

ath:AT5G20910

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000652	Aegilops tauschii	46.04	4.00e-69	254.00
IUUC-Atr-002467	Amborella trichopoda	69.75	2.00e-37	146.00
IUUC-Aly-005810	Arabidopsis lyrata	96.44	4.00e-150	523.00
IUUC-Bgr-012144	Blumeria graminis	42.22	2.00e-16	79.70
IUUC-Bdi-014952	Brachypodium distachyon	51.83	2.00e-78	285.00
IUUC-Bol-016249	Brassica oleracea	90.07	5.00e-143	499.00
IUUC-Bra-017222	Brassica rapa	86.62	2.00e-129	455.00
IUUC-Gma-044003	Glycine max	65.40	7.00e-97	346.00
IUUC-Hvu-047837	Hordeum vulgare	55.17	2.00e-51	194.00
IUUC-Lpe-051691	Leersia perrieri	51.64	1.00e-76	279.00
IUUC-Mtr-057776	Medicago truncatula	61.99	2.00e-93	334.00
IUUC-Mac-064671	Musa acuminata	56.07	8.00e-91	326.00
IUUC-Oba-075555	Oryza barthii	49.84	8.00e-73	266.00
IUUC-Obr-076610	Oryza brachyantha	50.49	4.00e-80	290.00
IUUC-Ogl-077481	Oryza glaberrima	49.84	8.00e-73	266.00
IUUC-Ogu-078564	Oryza glumaepatula	49.84	3.00e-72	264.00
IUUC-Oin-079836	Oryza indica	50.16	8.00e-73	266.00
IUUC-Olo-080714	Oryza longistaminata	52.94	2.00e-69	254.00
IUUC-Ome-081489	Oryza meridionalis	50.48	9.00e-73	266.00
IUUC-Oni-082870	Oryza nivara	50.16	8.00e-73	266.00
IUUC-Opu-083573	Oryza punctata	49.52	6.00e-77	280.00
IUUC-Oru-084631	Oryza rufipogon	50.16	8.00e-73	266.00
IUUC-Osa-086256	Oryza sativa	50.16	9.00e-73	266.00
IUUC-Ppa-095370	Physcomitrella patens	41.86	1.00e-61	229.00
IUUC-Pop-100000	Populus trichocarpa	66.78	3.00e-101	360.00
IUUC-Ppe-101308	Prunus persica	62.87	2.00e-101	361.00
IUUC-Ssl-108600	Sclerotinia sclerotiorum	47.83	1.00e-10	61.20
IUUC-Smo-109096	Selaginella moellendorffii	42.95	2.00e-55	208.00
IUUC-Sit-109993	Setaria italica	53.14	2.00e-82	298.00
IUUC-Sly-111289	Solanum lycopersicum	62.87	2.00e-100	358.00
IUUC-Stu-112307	Solanum tuberosum	62.54	1.00e-89	322.00
IUUC-Sbi-114382	Sorghum bicolor	52.53	1.00e-84	305.00
IUUC-Tca-121281	Theobroma cacao	70.14	1.00e-106	378.00
IUUC-Tae-123601	Triticum aestivum	52.70	9.00e-78	282.00
IUUC-Tur-126002	Triticum urartu	47.77	6.00e-47	180.00
IUUC-Vvi-131628	Vitis vinifera	64.04	2.00e-90	325.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence