iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000005268.1	ENSOART00000005744.1	ENSOARP00000005656.1
ENSOARG00000005268.1	ENSOART00000005745.1	ENSOARP00000005657.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.40e-36	126.0	412	720

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/HECT

   S: 7    krlevefvgEe...gldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlpl 92
           + +e+ +v+E+   g +++G+++efl+ll+++l+n+   lf  + + +++l+ n+++      +++l++ +G++++++l++g + + ++
   Q: 412  YTIEIVYVNENdhfGREQPGSKQEFLSLLMQQLENSP--LF--EGSLSKNLSLNSQAL-----KENLYYEAGKMIAISLVHGGPSPGFF 491
           678999999998899********************99..56..677777888888885.....689*********************** PP
   S: 93   sksfyklllgkklsledleevdpelyks.lkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvvey 180
           s++++++l   +   e+++ + +++ ++ + +i  ++  ++ ++ +dl++      + +++++  + g+ +i   +++k++  k+++ y
   Q: 492  SQTLFNCLAYGP---ENTQPILDDVSDFdVAQIMIRV--NTAATVADLNSL-----VHDYYKYLELIGCLRIITSISDKYMLAKDILVY 570
           ***********8...*************988888775..555555677655.....67789999999********************** PP
   S: 181  rlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevl.eefsseerkafLq.. 266
           ++ ++++  +e+f++G++++  le+++ + e  + +++++ e+++++ l++   ++ ++ +d +++  Fw+ + +++++ + +  ++  
   Q: 571  HVIKRVQAPFESFKQGLKTLGVLEKIQTYPEAFFHIFCHKPENLSAKILSD--LFTVHTLSDVQTL-GFWNSYlQAVEDGKSTVTMEdi 656
           *************************************************99..7888889999998.9998875777777766555455 PP
   S: 267  ..FvTgssrlPlgGfaelkprlfvirkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFe 334
             F+Tg++++P++Gf++ + ++ +++      ++P  n+  n+L LP  s++++++e++ +Ai++t ++e
   Q: 657  liFATGCKSIPPAGFKPSP-SIECLHM-----DFPVGNKHDNCLALPITSTYKEFQERMDFAIKNTLRLE 720
           55***************88.9999999.....*********************************87665 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MACGAAREGK SDTASLELLP SAPRKMNENK PGGSQNSTCV FCRKNDDCPI KYGEKKTNEK 60
WNLTVHYYCL LMSSGIWQRG KEEEGVYGFL IEDIRKEVTR ASKLKCSVCK KTGASIGCVA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGTGTG GCGCAGCGCG GGAAGGGAAA AGTGACACGG CCTCTCTGGA ACTTCTGCCC 60
AGCGCGCCTC GGTGAGTGGA TGTGGAACAG CAAGAAATGG AATATTCCAA GGAGAGAAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR034732--EPHD
IPR000569--HECT_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51805--EPHD
PS01359--ZF_PHD_1

Pfam

PF00632--HECT

SMART

SM00119--HECTc
SM00249--PHD

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding

KEGG

oas:101114906

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001501	Ailuropoda melanoleuca	88.78	0.00e+00	1323.00
IUUC-Apl-003763	Anas platyrhynchos	58.63	0.00e+00	842.00
IUUC-Aca-004328	Anolis carolinensis	59.65	0.00e+00	863.00
IUUC-Ame-011288	Astyanax mexicanus	39.69	2.00e-160	559.00
IUUC-Bta-012496	Bos taurus	96.44	0.00e+00	1426.00
IUUC-Cja-019756	Callithrix jacchus	85.65	0.00e+00	1283.00
IUUC-Cfa-020806	Canis familiaris	86.03	0.00e+00	1319.00
IUUC-Cpo-022519	Cavia porcellus	83.90	0.00e+00	1237.00
IUUC-Csa-023957	Chlorocebus sabaeus	86.65	0.00e+00	1297.00
IUUC-Cho-024375	Choloepus hoffmanni	78.84	0.00e+00	1129.00
IUUC-Cin-025325	Ciona intestinalis	41.89	4.00e-67	247.00
IUUC-Csv-026262	Ciona savignyi	42.19	3.00e-68	252.00
IUUC-Dre-027829	Danio rerio	39.65	2.00e-150	526.00
IUUC-Dno-029362	Dasypus novemcinctus	84.90	0.00e+00	1249.00
IUUC-Dor-030710	Dipodomys ordii	80.40	0.00e+00	1211.00
IUUC-Dse-031248	Dothistroma septosporum	38.46	1.70e-02	35.00
IUUC-Dme-031692	Drosophila melanogaster	35.09	5.00e-42	165.00
IUUC-Ete-032282	Echinops telfairi	80.46	0.00e+00	882.00
IUUC-Eca-033963	Equus caballus	88.07	0.00e+00	1321.00
IUUC-Eeu-035029	Erinaceus europaeus	85.23	0.00e+00	1277.00
IUUC-Fca-036229	Felis catus	89.35	0.00e+00	1333.00
IUUC-Fal-037015	Ficedula albicollis	57.82	0.00e+00	865.00
IUUC-Gmo-039715	Gadus morhua	40.16	1.00e-77	283.00
IUUC-Gga-040298	Gallus gallus	57.88	0.00e+00	888.00
IUUC-Gac-041444	Gasterosteus aculeatus	38.91	3.00e-139	488.00
IUUC-Ggo-045456	Gorilla gorilla	86.36	0.00e+00	1286.00
IUUC-Hsa-046297	Homo sapiens	86.38	0.00e+00	1295.00
IUUC-Itr-047897	Ictidomys tridecemlineatus	84.80	0.00e+00	894.00
IUUC-Lch-050287	Latimeria chalumnae	66.93	2.00e-106	380.00
IUUC-Loc-052839	Lepisosteus oculatus	50.42	3.00e-31	126.00
IUUC-Laf-053581	Loxodonta africana	83.94	0.00e+00	1246.00
IUUC-Mcc-055615	Macaca mulatta	86.38	0.00e+00	1296.00
IUUC-Meu-056753	Macropus eugenii	47.86	3.00e-125	442.00
IUUC-Mga-059902	Meleagris gallopavo	57.55	0.00e+00	890.00
IUUC-Mmr-061522	Microcebus murinus	87.07	0.00e+00	1309.00
IUUC-Mdo-063022	Monodelphis domestica	61.76	0.00e+00	882.00
IUUC-Mmu-063609	Mus musculus	74.14	0.00e+00	1140.00
IUUC-Mpu-066656	Mustela putorius furo	87.19	0.00e+00	1349.00
IUUC-Mlu-067011	Myotis lucifugus	86.72	0.00e+00	1278.00
IUUC-Nle-069949	Nomascus leucogenys	86.08	0.00e+00	1288.00
IUUC-Opr-071224	Ochotona princeps	80.99	3.00e-127	449.00
IUUC-Ont-072174	Oreochromis niloticus	36.78	5.00e-135	474.00
IUUC-Oan-072712	Ornithorhynchus anatinus	65.99	0.00e+00	951.00
IUUC-Ocu-073776	Oryctolagus cuniculus	86.22	0.00e+00	1283.00
IUUC-Ola-087247	Oryzias latipes	37.01	2.00e-129	456.00
IUUC-Oga-088094	Otolemur garnettii	83.41	0.00e+00	1187.00
IUUC-Ptr-090634	Pan troglodytes	86.51	0.00e+00	1291.00
IUUC-Pan-092876	Papio anubis	86.51	0.00e+00	1295.00
IUUC-Psi-093580	Pelodiscus sinensis	60.55	0.00e+00	878.00
IUUC-Pma-094295	Petromyzon marinus	53.41	3.00e-72	264.00
IUUC-Pfo-096351	Poecilia formosa	39.07	3.00e-147	515.00
IUUC-Pab-097596	Pongo abelii	86.51	0.00e+00	1295.00
IUUC-Pca-100309	Procavia capensis	77.67	0.00e+00	1154.00
IUUC-Pva-102526	Pteropus vampyrus	89.73	0.00e+00	832.00
IUUC-Rno-105432	Rattus norvegicus	77.98	0.00e+00	1179.00
IUUC-Sha-107089	Sarcophilus harrisii	62.32	0.00e+00	994.00
IUUC-Sar-113667	Sorex araneus	67.80	0.00e+00	737.00
IUUC-Ssc-116200	Sus scrofa	91.74	0.00e+00	1367.00
IUUC-Tgu-116467	Taeniopygia guttata	57.08	0.00e+00	847.00
IUUC-Tru-117690	Takifugu rubripes	39.12	2.00e-154	539.00
IUUC-Tsy-119481	Tarsius syrichta	84.40	0.00e+00	882.00
IUUC-Tni-119669	Tetraodon nigroviridis	37.18	1.00e-132	467.00
IUUC-Tbe-127241	Tupaia belangeri	78.09	0.00e+00	1127.00
IUUC-Ttr-129057	Tursiops truncatus	83.07	0.00e+00	1191.00
IUUC-Vpa-130685	Vicugna pacos	88.89	0.00e+00	1290.00
IUUC-Xtr-132555	Xenopus tropicalis	51.72	0.00e+00	744.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence