iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pab-097641

Ensembl Protein ID

ENSPPYP00000006278.2

UniProt Accession

H2NKC0; H2NKC0_PONAB

Genbank Protein ID

ENSPPYP00000006278

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01163730

Gene Name

ARHGEF7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000005508.2	ENSPPYT00000006526.2	ENSPPYP00000006278.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.20e-15	56.5	167	221

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +v++ ++++ +n+deL++ kGdv++v     +++gW++g  +l+g+ G fP+n+v++++
   Q: 167  VVRAKFNFQQTNEDELSFSKGDVIHVT--RVEEGGWWEG--TLNGRTGWFPSNYVREVK 221
           78999*********************7..999*******..8**************996 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MNSAEQTVTW LITLGVLESP KKTISDPEGF LQASLKDGVV LCRLLERLLP GTIEKVYPEP 60
RSESECLRNI REFLRGCGAS LRLETFDAND LYQGQNFNKV LSSLVTLNKV TADIGLGSDS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCACGGCCTG GAGCGGAGGC TGCGCAGGGC GCGGGGCGGC GCGGGCCGGG CGCGGGCCGG 60
GCGGACGGCC GCGTCTTTCT TCTCCTGGCG GTGATGTCAT TGGGCGACGG CGGCCGAGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-1185--Reference proteome

Interpro

IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR032409--GEF_CC
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50021--CH
PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF16523--betaPIX_CC
PF00307--CH
PF00169--PH
PF00621--RhoGEF
PF07653--SH3_2

PRINTS

PR00452--SH3DOMAIN

SMART

SM00033--CH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0005925--C:focal adhesion
GO:0030027--C:lamellipodium
GO:0043005--C:neuron projection
GO:0043025--C:neuronal cell body
GO:0005886--C:plasma membrane
GO:0043234--C:protein complex
GO:0000322--C:storage vacuole
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0048041--P:focal adhesion assembly
GO:0007030--P:Golgi organization
GO:0002244--P:hematopoietic progenitor cell differentiation
GO:0035556--P:intracellular signal transduction
GO:0030032--P:lamellipodium assembly
GO:0043065--P:positive regulation of apoptotic process
GO:0010763--P:positive regulation of fibroblast migration
GO:0060124--P:positive regulation of growth hormone secretion
GO:2000394--P:positive regulation of lamellipodium morphogenesis
GO:0032092--P:positive regulation of protein binding
GO:1900026--P:positive regulation of substrate adhesion-dependent cell spreading
GO:1904424--P:regulation of GTP binding
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001259	Ailuropoda melanoleuca	91.46	0.00e+00	1262.00
IUUC-Aca-004591	Anolis carolinensis	91.01	0.00e+00	1217.00
IUUC-Ago-008003	Ashbya gossypii	25.00	8.00e-15	75.90
IUUC-Ame-010759	Astyanax mexicanus	75.87	0.00e+00	1051.00
IUUC-Bta-013328	Bos taurus	92.84	0.00e+00	1258.00
IUUC-Bci-013864	Botrytis cinerea	41.54	6.00e-12	67.00
IUUC-Cja-018742	Callithrix jacchus	98.42	0.00e+00	1182.00
IUUC-Cfa-020756	Canis familiaris	94.74	0.00e+00	1317.00
IUUC-Cpo-021284	Cavia porcellus	93.23	0.00e+00	1215.00
IUUC-Csa-023162	Chlorocebus sabaeus	99.72	0.00e+00	1365.00
IUUC-Cho-024736	Choloepus hoffmanni	73.62	5.00e-174	604.00
IUUC-Cin-025535	Ciona intestinalis	40.31	4.00e-94	338.00
IUUC-Cgl-026676	Colletotrichum gloeosporioides	41.43	1.00e-11	66.20
IUUC-Cne-026866	Cryptococcus neoformans	50.79	1.00e-13	72.80
IUUC-Dre-028646	Danio rerio	66.44	0.00e+00	1057.00
IUUC-Dno-029461	Dasypus novemcinctus	95.51	0.00e+00	1317.00
IUUC-Dor-030623	Dipodomys ordii	80.83	0.00e+00	1007.00
IUUC-Dme-032219	Drosophila melanogaster	46.25	2.00e-102	367.00
IUUC-Ete-032236	Echinops telfairi	80.45	0.00e+00	808.00
IUUC-Eca-034137	Equus caballus	95.87	0.00e+00	1148.00
IUUC-Fca-035742	Felis catus	96.11	0.00e+00	1298.00
IUUC-Fal-037205	Ficedula albicollis	93.33	0.00e+00	980.00
IUUC-Fox-037757	Fusarium oxysporum	38.89	9.00e-12	66.20
IUUC-Fso-038433	Fusarium solani	38.89	9.00e-12	66.20
IUUC-Gmo-039475	Gadus morhua	76.12	0.00e+00	1144.00
IUUC-Gga-040539	Gallus gallus	94.27	0.00e+00	1153.00
IUUC-Gac-042615	Gasterosteus aculeatus	73.13	0.00e+00	1070.00
IUUC-Ggo-044470	Gorilla gorilla	98.43	0.00e+00	1193.00
IUUC-Hsa-046398	Homo sapiens	96.73	0.00e+00	1343.00
IUUC-Loc-052146	Lepisosteus oculatus	84.43	0.00e+00	1173.00
IUUC-Lma-053273	Leptosphaeria maculans	40.32	8.00e-11	63.20
IUUC-Laf-053891	Loxodonta africana	91.43	0.00e+00	1254.00
IUUC-Mcc-055483	Macaca mulatta	96.59	0.00e+00	1343.00
IUUC-Mla-059044	Melampsora laricipopulina	26.58	2.00e-18	88.20
IUUC-Mga-059410	Meleagris gallopavo	91.04	0.00e+00	1123.00
IUUC-Mmr-060758	Microcebus murinus	96.91	0.00e+00	1283.00
IUUC-Mdo-061900	Monodelphis domestica	94.40	0.00e+00	1467.00
IUUC-Mmu-063849	Mus musculus	93.96	0.00e+00	1252.00
IUUC-Mpu-065876	Mustela putorius furo	93.96	0.00e+00	1310.00
IUUC-Mlu-067970	Myotis lucifugus	95.23	0.00e+00	1142.00
IUUC-Nle-069685	Nomascus leucogenys	96.90	0.00e+00	1255.00
IUUC-Opr-071132	Ochotona princeps	61.62	0.00e+00	653.00
IUUC-Ont-071815	Oreochromis niloticus	68.87	0.00e+00	1111.00
IUUC-Oan-073057	Ornithorhynchus anatinus	91.89	0.00e+00	974.00
IUUC-Ola-086663	Oryzias latipes	66.30	0.00e+00	966.00
IUUC-Olu-087789	Ostreococcus lucimarinus	29.47	1.50e-02	32.70
IUUC-Oga-088103	Otolemur garnettii	94.16	0.00e+00	1100.00
IUUC-Ptr-091162	Pan troglodytes	95.89	0.00e+00	1232.00
IUUC-Pan-092093	Papio anubis	87.52	0.00e+00	1208.00
IUUC-Pma-094701	Petromyzon marinus	64.06	2.00e-134	472.00
IUUC-Pfo-096736	Poecilia formosa	75.37	0.00e+00	1168.00
IUUC-Pva-102819	Pteropus vampyrus	92.28	0.00e+00	1243.00
IUUC-Pte-104123	Pyrenophora teres	42.86	1.00e-10	62.40
IUUC-Pyt-104567	Pyrenophora triticirepentis	42.86	1.00e-10	62.40
IUUC-Rno-106099	Rattus norvegicus	93.96	0.00e+00	1256.00
IUUC-Sha-106845	Sarcophilus harrisii	93.64	0.00e+00	1302.00
IUUC-Ssl-108538	Sclerotinia sclerotiorum	42.37	4.00e-11	63.90
IUUC-Sly-111123	Solanum lycopersicum	46.15	7.00e-10	57.80
IUUC-Stu-112434	Solanum tuberosum	46.15	8.00e-10	57.80
IUUC-Ssc-116036	Sus scrofa	94.45	0.00e+00	1294.00
IUUC-Tgu-117498	Taeniopygia guttata	89.33	0.00e+00	1215.00
IUUC-Tru-118278	Takifugu rubripes	74.09	0.00e+00	912.00
IUUC-Tsy-118990	Tarsius syrichta	95.11	0.00e+00	980.00
IUUC-Tni-120852	Tetraodon nigroviridis	74.44	0.00e+00	1140.00
IUUC-Tvi-122534	Trichoderma virens	41.67	9.00e-12	66.20
IUUC-Ttr-128922	Tursiops truncatus	87.15	0.00e+00	1082.00
IUUC-Xtr-132012	Xenopus tropicalis	84.15	0.00e+00	1060.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence