iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ssc-115390

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

CU062444

Gene Name

GNB5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000004622.2	ENSSSCT00000005105.2	ENSSSCP00000004981.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-42	142.1	194	233
UBD/Beta-Prp	1.20e-53	182.5	189	395

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sd.tllvsGsdDgtikvWDlrtgvllks 38
           Ht+  ++++f  sd   ++++s+Dgt+ +WD+ +g ll+s
   Q: 194  HTNYLSACSFtnSDmQQILTASGDGTCALWDVESGQLLQS 233
           999999*****988999******************99986 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgk.ilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sgdklvsGshdrtirvwdletgqclee 131
           +s+  h++  +a++f +++   ++t+s D+t  +wd+++g+ +++++gh ++vl+l++ p  +g+++vsG+ d+ ++vwd+++gqc++ 
   Q: 189  KSVAMHTNYLSACSFTNSDMqQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPseTGNTFVSGGCDKKAMVWDMRSGQCIQ- 276
           5668899999999998876559**************************************9778************************. PP
   S: 132  tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl.tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtln 219
            ++ h++ +n+v++ p+g+ ++sGs+D t+rl+dl+ ++ +    ++       s++f+ +g+ l +g +d t+++wd+ +g+ v +l 
   Q: 277  AFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYsKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILF 365
           *******************************************95333556778999******************************** PP
   S: 220  ghtdnvksvrfspnderlvsgssDgsiriW 249
           gh++ v+ +r+sp+++ + sgs D ++r+W
   Q: 366  GHENRVSTLRVSPDGTAFCSGSWDHTLRVW 395
           ****************************** PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MCDQTFLVNV FGSCDKCFKQ RALRPVFKKS QQLSYCSVCA EIMATDGLHE NETLASLKSE 60
AESLKGKLEE ERAKLHDVEL HQVAERVEAL GQFVMKTRRT LKGHGNKVLC MDWCKDKRRI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGTGATC AGACCTTTCT AGTTAATGTA TTTGGCTCCT GTGACAAATG TTTCAAACAA 60
CGGGCTCTAA GACCAGTTTT CAAGAAATCT CAACAGCTCA GCTATTGTTC AGTATGTGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005096--F:GTPase activator activity
GO:1901386--P:negative regulation of voltage-gated calcium channel activity
GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001811	Ailuropoda melanoleuca	92.42	0.00e+00	763.00
IUUC-Apl-003399	Anas platyrhynchos	98.73	0.00e+00	646.00
IUUC-Aca-004861	Anolis carolinensis	93.18	0.00e+00	776.00
IUUC-Ame-011851	Astyanax mexicanus	92.05	0.00e+00	682.00
IUUC-Bta-012438	Bos taurus	98.87	0.00e+00	727.00
IUUC-Cel-018408	Caenorhabditis elegans	64.45	6.00e-138	483.00
IUUC-Cja-019086	Callithrix jacchus	98.98	0.00e+00	811.00
IUUC-Cfa-021255	Canis familiaris	96.95	0.00e+00	754.00
IUUC-Cpo-021398	Cavia porcellus	97.22	0.00e+00	808.00
IUUC-Csa-023776	Chlorocebus sabaeus	98.87	0.00e+00	726.00
IUUC-Cin-025305	Ciona intestinalis	58.04	2.00e-130	458.00
IUUC-Csv-026058	Ciona savignyi	58.20	2.00e-126	445.00
IUUC-Dre-028432	Danio rerio	84.34	0.00e+00	673.00
IUUC-Dno-029958	Dasypus novemcinctus	86.60	6.00e-147	512.00
IUUC-Dor-031013	Dipodomys ordii	98.44	1.00e-151	528.00
IUUC-Dme-031889	Drosophila melanogaster	68.41	3.00e-148	517.00
IUUC-Ete-033033	Echinops telfairi	80.38	2.00e-97	348.00
IUUC-Eca-033977	Equus caballus	93.18	0.00e+00	763.00
IUUC-Eeu-035079	Erinaceus europaeus	97.96	0.00e+00	797.00
IUUC-Fca-035693	Felis catus	91.96	0.00e+00	757.00
IUUC-Fal-037345	Ficedula albicollis	97.74	0.00e+00	723.00
IUUC-Gmo-039222	Gadus morhua	91.24	0.00e+00	655.00
IUUC-Gga-040320	Gallus gallus	98.31	0.00e+00	725.00
IUUC-Gac-042644	Gasterosteus aculeatus	91.53	0.00e+00	684.00
IUUC-Ggo-044489	Gorilla gorilla	94.96	0.00e+00	771.00
IUUC-Hsa-046434	Homo sapiens	98.99	0.00e+00	815.00
IUUC-Itr-048771	Ictidomys tridecemlineatus	93.06	2.00e-175	607.00
IUUC-Loc-052790	Lepisosteus oculatus	90.33	0.00e+00	718.00
IUUC-Laf-054255	Loxodonta africana	97.72	0.00e+00	801.00
IUUC-Mcc-055610	Macaca mulatta	98.48	0.00e+00	806.00
IUUC-Meu-056819	Macropus eugenii	86.77	0.00e+00	691.00
IUUC-Mga-059740	Meleagris gallopavo	87.31	0.00e+00	714.00
IUUC-Mmr-061221	Microcebus murinus	98.74	0.00e+00	814.00
IUUC-Mdo-062619	Monodelphis domestica	98.02	0.00e+00	721.00
IUUC-Mmu-064266	Mus musculus	98.74	0.00e+00	815.00
IUUC-Mpu-065766	Mustela putorius furo	98.68	4.00e-180	623.00
IUUC-Mlu-067221	Myotis lucifugus	91.18	0.00e+00	756.00
IUUC-Nle-069515	Nomascus leucogenys	99.05	0.00e+00	655.00
IUUC-Opr-070195	Ochotona princeps	90.61	0.00e+00	723.00
IUUC-Ont-071535	Oreochromis niloticus	78.79	6.00e-171	592.00
IUUC-Oan-072899	Ornithorhynchus anatinus	98.38	1.00e-107	381.00
IUUC-Ocu-074666	Oryctolagus cuniculus	99.01	2.00e-180	624.00
IUUC-Ola-086578	Oryzias latipes	92.63	0.00e+00	649.00
IUUC-Oga-089090	Otolemur garnettii	98.24	0.00e+00	810.00
IUUC-Oar-090017	Ovis aries	92.39	0.00e+00	751.00
IUUC-Ptr-091280	Pan troglodytes	89.65	0.00e+00	723.00
IUUC-Pan-092198	Papio anubis	98.43	0.00e+00	655.00
IUUC-Psi-093030	Pelodiscus sinensis	85.61	0.00e+00	716.00
IUUC-Pma-094140	Petromyzon marinus	82.94	2.00e-103	367.00
IUUC-Pfo-097182	Poecilia formosa	92.37	0.00e+00	663.00
IUUC-Pab-098157	Pongo abelii	99.15	0.00e+00	731.00
IUUC-Pca-100988	Procavia capensis	77.53	3.00e-171	594.00
IUUC-Pva-102232	Pteropus vampyrus	86.32	3.00e-176	610.00
IUUC-Rno-105526	Rattus norvegicus	95.51	0.00e+00	692.00
IUUC-Sce-106298	Saccharomyces cerevisiae	34.79	9.00e-68	250.00
IUUC-Sha-106754	Sarcophilus harrisii	97.22	0.00e+00	756.00
IUUC-Tgu-117377	Taeniopygia guttata	87.31	0.00e+00	699.00
IUUC-Tru-117938	Takifugu rubripes	92.37	0.00e+00	651.00
IUUC-Tsy-119392	Tarsius syrichta	84.85	0.00e+00	664.00
IUUC-Tni-119834	Tetraodon nigroviridis	72.73	3.00e-164	570.00
IUUC-Tbe-127469	Tupaia belangeri	96.02	0.00e+00	731.00
IUUC-Ttr-128252	Tursiops truncatus	95.21	0.00e+00	771.00
IUUC-Vpa-130173	Vicugna pacos	80.42	6.00e-157	546.00
IUUC-Xtr-131803	Xenopus tropicalis	91.67	0.00e+00	726.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence