iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSG00000215277.8	ENST00000399910.5	ENSP00000382794.1
ENSG00000215277.8	ENST00000492621.5	ENSP00000450766.1
ENSG00000215277.8	ENST00000399905.5	ENSP00000382789.1
ENSG00000215277.8	ENST00000470456.1	ENSP00000451124.1

Annotation

Cancer Mutation
ICGC	COSMIC	IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	THPA	HPM
DNA & RNA Element
TRANSFAC	TargetScan	miRcode	RAID2
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus
Protein Expression/Proteomics
THPA	HPM	GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	26.62	4.00e-04	40.40	IUUC-Sce-106217

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Homo sapiens

Protein Sequence
(Fasta)

MDWFHCNQCF RKDGAHFFVT SCGHIFCKKC VTLEKCAVCG TACKHLALSD NLKPQEKMFF 60
KSPVETALQY FSHISQVWSF QKKQTDLLIA FYKHRITKLE TAMQEAQQAL VSQDKELSVL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAATGAGTC ATGGGAAATG AAAAAATGTC GAATTTGCCT CTAGCCTTTC CTGACAACCT 60
TAGAAAGCAC TGAGGAAAAA TTTGATAGAT TCATTTGTAT ACATTCAGAT TTGAAGACTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1

Gene Ontology

GO:0000795--C:synaptonemal complex
GO:0046872--F:metal ion binding
GO:0019789--F:SUMO transferase activity
GO:0016925--P:protein sumoylation
GO:0007129--P:synapsis

KEGG

hsa:100507650

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001729	Ailuropoda melanoleuca	85.38	3.00e-129	454.00
IUUC-Ame-010703	Astyanax mexicanus	46.97	8.00e-32	129.00
IUUC-Bta-012656	Bos taurus	83.39	5.00e-122	430.00
IUUC-Cel-018486	Caenorhabditis elegans	31.45	3.00e-14	72.80
IUUC-Cja-019592	Callithrix jacchus	90.07	7.00e-139	486.00
IUUC-Cfa-020989	Canis familiaris	85.38	3.00e-130	457.00
IUUC-Cpo-022199	Cavia porcellus	77.08	2.00e-120	425.00
IUUC-Cho-024808	Choloepus hoffmanni	81.06	3.00e-118	417.00
IUUC-Cin-025593	Ciona intestinalis	32.85	2.00e-12	66.60
IUUC-Csv-025924	Ciona savignyi	32.37	4.00e-12	64.30
IUUC-Dno-029599	Dasypus novemcinctus	82.62	2.00e-132	464.00
IUUC-Dor-030719	Dipodomys ordii	76.00	4.00e-116	410.00
IUUC-Dme-031890	Drosophila melanogaster	28.06	3.00e-06	45.10
IUUC-Eca-034173	Equus caballus	87.67	1.00e-134	472.00
IUUC-Fca-035686	Felis catus	85.71	1.00e-131	462.00
IUUC-Lch-049529	Latimeria chalumnae	52.81	1.00e-53	202.00
IUUC-Laf-053762	Loxodonta africana	84.05	2.00e-98	352.00
IUUC-Meu-056211	Macropus eugenii	62.95	1.00e-62	232.00
IUUC-Mvi-060212	Microbotryum violaceum	18.57	5.00e-06	46.20
IUUC-Mpu-066296	Mustela putorius furo	65.09	2.00e-103	368.00
IUUC-Mlu-067791	Myotis lucifugus	82.78	7.00e-132	463.00
IUUC-Ncr-068752	Neurospora crassa	56.52	1.90e-02	34.70
IUUC-Nle-069857	Nomascus leucogenys	98.00	4.00e-152	530.00
IUUC-Opr-070576	Ochotona princeps	80.00	1.00e-99	356.00
IUUC-Ont-072176	Oreochromis niloticus	40.11	2.00e-32	132.00
IUUC-Oan-073188	Ornithorhynchus anatinus	71.09	1.00e-88	319.00
IUUC-Oar-089717	Ovis aries	83.95	4.00e-122	430.00
IUUC-Ptr-090600	Pan troglodytes	99.33	8.00e-155	539.00
IUUC-Pfo-096367	Poecilia formosa	39.44	3.00e-33	135.00
IUUC-Pab-098207	Pongo abelii	96.67	6.00e-153	533.00
IUUC-Pca-100854	Procavia capensis	74.01	3.00e-98	351.00
IUUC-Pva-102370	Pteropus vampyrus	75.42	3.00e-110	391.00
IUUC-Sce-106217	Saccharomyces cerevisiae	25.18	3.00e-03	37.00
IUUC-Sre-114928	Sporisorium reilianum	23.60	3.60e-02	32.30
IUUC-Tsy-119403	Tarsius syrichta	78.48	5.00e-113	400.00
IUUC-Vpa-130712	Vicugna pacos	82.06	5.00e-122	430.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence