iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-036766

Ensembl Protein ID

ENSFALP00000006329.1

UniProt Accession

U3JU75; U3JU75_FICAL

Genbank Protein ID

ENSFALP00000006329

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01010984

Gene Name

USP2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000006060.1	ENSFALT00000006358.1	ENSFALP00000006329.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.40e-101	338.5	252	582

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgy 87
           tGl+NlgNtC+mNS+LQcLsn++elr+++l+ ++ ++ln++  + + ++l+++++kl++ lw +s +++vsp+e++++++++a++f gy
   Q: 252  TGLRNLGNTCFMNSILQCLSNTKELRDYCLQnQYLRDLNNN--SRMRTALMSEFAKLIQLLWtSSPNESVSPSEFKTQIQRYAPRFVGY 338
           7******************************6666777655..78*****************999999********************* PP
   S: 88   eqqDaqEflaflldqleeelkk...eknkpkeeeeeed...kselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfl 170
           +qqDaqEfl+flld+l++e+++   +   p+ ++   d   + e+s++ +++ +++++s isdlF gqlks+++c ec+  s+ ++pf+
   Q: 339  NQQDAQEFLRFLLDGLHSEVNRvlvR---PRASTDTLDhlpDDEKSRQMWRRYQEREDSRISDLFVGQLKSSLTCSECGYCSTAFDPFW 424
           ********************995552...444443333000345666699*************************************** PP
   S: 171  dlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple. 258
           dlslp+p+k    + +l dcL+ ftke+ l+g++k  c +ck++++++kk++++k+P++L+lhLkRf  se++ +++k+++ v+fpl+ 
   Q: 425  DLSLPIPKKGYG-EVTLMDCLRLFTKEDVLDGDEKPTCCRCKARTRCTKKFSIQKFPKILVLHLKRF--SEARIRSSKLTTFVNFPLKd 510
           ********9976.779***************************************************..9999**************** PP
   S: 259  LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYk 336
           Ldl++  +++++    +  Y+L+av +HsG++ +GHY+ay+k+   + W  f+Ds+Vt+++ + v +   s+aY+lfY+
   Q: 511  LDLRELASQSCN----HAVYNLYAVSNHSGTTMGGHYTAYCKSPVSSeWHSFNDSRVTPMSSSHVRS---SDAYLLFYE 582
           *******99775....679************************65555*******************...********8 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MSQLSSTLKR YVDSSRYAET TYSKVPSGYS SYSSYGSTLC TAYADSDKIG FKASYLPSPR 60
YHHAGGLSPT SGYDSGRLYP DPSIRLSPSY IRTQPRPPGA GLSGGACYTF SGSPGSPTGY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCCAGC TCTCCTCCAC CCTGAAGCGA TACGTGGACT CCTCCCGCTA CGCCGAGACC 60
ACCTACAGCA AAGTGCCCAG CGGCTACAGC TCCTACAGCT CCTATGGGTC CACCCTGTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005938--C:cell cortex
GO:0005634--C:nucleus
GO:0048471--C:perinuclear region of cytoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0032922--P:circadian regulation of gene expression
GO:0043153--P:entrainment of circadian clock by photoperiod
GO:0045475--P:locomotor rhythm
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045931--P:positive regulation of mitotic cell cycle
GO:0016579--P:protein deubiquitination
GO:0050821--P:protein stabilization
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001988	Ailuropoda melanoleuca	65.09	0.00e+00	686.00
IUUC-Aca-005132	Anolis carolinensis	66.72	0.00e+00	738.00
IUUC-Afu-009001	Aspergillus fumigatus	33.88	2.00e-52	201.00
IUUC-Ang-009844	Aspergillus niger	33.88	2.00e-52	200.00
IUUC-Ame-011102	Astyanax mexicanus	75.57	2.00e-149	521.00
IUUC-Bta-012529	Bos taurus	64.22	0.00e+00	667.00
IUUC-Bra-016678	Brassica rapa	36.71	2.00e-49	189.00
IUUC-Cja-019016	Callithrix jacchus	61.91	0.00e+00	627.00
IUUC-Cfa-020714	Canis familiaris	64.60	0.00e+00	692.00
IUUC-Cpo-021727	Cavia porcellus	64.13	0.00e+00	672.00
IUUC-Csa-023071	Chlorocebus sabaeus	82.47	6.00e-169	586.00
IUUC-Cin-025797	Ciona intestinalis	53.60	1.00e-101	362.00
IUUC-Csv-026132	Ciona savignyi	52.45	1.00e-104	373.00
IUUC-Dre-027872	Danio rerio	80.70	2.00e-166	578.00
IUUC-Dno-029329	Dasypus novemcinctus	65.14	0.00e+00	713.00
IUUC-Dor-030574	Dipodomys ordii	64.32	0.00e+00	690.00
IUUC-Dse-031463	Dothistroma septosporum	34.56	6.00e-44	172.00
IUUC-Dme-032208	Drosophila melanogaster	49.85	6.00e-87	315.00
IUUC-Ete-032725	Echinops telfairi	50.70	2.00e-88	319.00
IUUC-Eca-033361	Equus caballus	64.60	0.00e+00	676.00
IUUC-Eeu-035272	Erinaceus europaeus	84.70	2.00e-85	309.00
IUUC-Fca-036497	Felis catus	64.76	0.00e+00	681.00
IUUC-Gmo-039129	Gadus morhua	66.77	1.00e-125	442.00
IUUC-Gga-040889	Gallus gallus	97.02	6.00e-167	580.00
IUUC-Gac-042475	Gasterosteus aculeatus	69.45	5.00e-139	486.00
IUUC-Ggo-044814	Gorilla gorilla	77.43	6.00e-150	523.00
IUUC-Hsa-045937	Homo sapiens	62.85	0.00e+00	655.00
IUUC-Itr-048171	Ictidomys tridecemlineatus	63.49	0.00e+00	684.00
IUUC-Lch-050527	Latimeria chalumnae	65.96	1.00e-175	609.00
IUUC-Loc-052697	Lepisosteus oculatus	77.84	2.00e-165	575.00
IUUC-Lma-053021	Leptosphaeria maculans	35.90	5.00e-56	213.00
IUUC-Laf-054167	Loxodonta africana	62.60	0.00e+00	682.00
IUUC-Mcc-055584	Macaca mulatta	64.05	0.00e+00	674.00
IUUC-Meu-056542	Macropus eugenii	64.45	0.00e+00	672.00
IUUC-Mga-060020	Meleagris gallopavo	80.41	0.00e+00	864.00
IUUC-Mmr-060989	Microcebus murinus	64.27	0.00e+00	679.00
IUUC-Mdo-062761	Monodelphis domestica	65.52	0.00e+00	679.00
IUUC-Mmu-063710	Mus musculus	63.46	0.00e+00	678.00
IUUC-Mpu-066573	Mustela putorius furo	64.60	0.00e+00	679.00
IUUC-Mlu-067359	Myotis lucifugus	45.57	4.00e-78	285.00
IUUC-Nfi-068410	Neosartorya fischeri	34.44	8.00e-52	199.00
IUUC-Nle-070013	Nomascus leucogenys	62.78	0.00e+00	630.00
IUUC-Opr-070907	Ochotona princeps	63.36	0.00e+00	668.00
IUUC-Ont-071944	Oreochromis niloticus	81.09	4.00e-169	587.00
IUUC-Oan-073105	Ornithorhynchus anatinus	72.62	4.00e-138	483.00
IUUC-Ocu-073941	Oryctolagus cuniculus	62.75	0.00e+00	661.00
IUUC-Ola-087412	Oryzias latipes	75.54	5.00e-156	544.00
IUUC-Oga-088973	Otolemur garnettii	64.11	0.00e+00	677.00
IUUC-Oar-089916	Ovis aries	64.54	0.00e+00	701.00
IUUC-Ptr-090998	Pan troglodytes	63.40	0.00e+00	660.00
IUUC-Pan-092686	Papio anubis	64.05	0.00e+00	673.00
IUUC-Psi-093284	Pelodiscus sinensis	77.26	2.00e-131	461.00
IUUC-Pma-094462	Petromyzon marinus	68.95	6.00e-80	289.00
IUUC-Pno-094986	Phaeosphaeria nodorum	32.64	2.00e-42	167.00
IUUC-Pfo-097352	Poecilia formosa	79.32	7.00e-173	600.00
IUUC-Pab-098688	Pongo abelii	57.59	6.00e-160	556.00
IUUC-Pca-100205	Procavia capensis	80.12	4.00e-166	577.00
IUUC-Pva-103188	Pteropus vampyrus	63.13	0.00e+00	659.00
IUUC-Pte-104348	Pyrenophora teres	33.33	5.00e-43	169.00
IUUC-Rno-105853	Rattus norvegicus	62.98	0.00e+00	698.00
IUUC-Sha-107237	Sarcophilus harrisii	64.38	0.00e+00	687.00
IUUC-Sar-113103	Sorex araneus	78.96	3.00e-158	550.00
IUUC-Ssc-115955	Sus scrofa	64.38	0.00e+00	666.00
IUUC-Tgu-116894	Taeniopygia guttata	88.79	0.00e+00	774.00
IUUC-Tru-117703	Takifugu rubripes	66.57	1.00e-130	459.00
IUUC-Tsy-118879	Tarsius syrichta	75.59	4.00e-180	624.00
IUUC-Tni-119866	Tetraodon nigroviridis	78.12	2.00e-156	544.00
IUUC-Tbe-127367	Tupaia belangeri	51.51	5.00e-90	325.00
IUUC-Ttr-128773	Tursiops truncatus	63.55	0.00e+00	665.00
IUUC-Vpa-130402	Vicugna pacos	84.16	9.00e-105	373.00
IUUC-Xtr-132658	Xenopus tropicalis	63.19	7.00e-165	573.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence