iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oga-088973

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03130794

Gene Name

USP2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000007337.2	ENSOGAT00000007342.2	ENSOGAP00000006569.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.00e-98	329.7	269	598

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgye 88
           Gl+NlgNtC+mNS+LQcLsn++elr+++l+  + ++l++   ++ +++l+++++kl++ +w +s + +vsp+e++++++++a++f gy+
   Q: 269  GLRNLGNTCFMNSILQCLSNTRELRDYCLQrLYMRDLSHG--SSAHTALMEEFAKLIQTIWtSSPNDVVSPSEFKTQIQRYAPRFVGYN 355
           9*****************************7777888776..7899***************889999********************** PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           qqDaqEfl+flld+l++e+++ +  pk++ e+ d  +l+d+      ++k  ++++s i dlF gqlks+++c +c+  s+ ++pf+dl
   Q: 356  QQDAQEFLRFLLDGLHNEVNRVAPRPKSNPENLD--HLPDDekgrqMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDL 442
           *******************884444444444444..44444446669****************************************** PP
   S: 173  slpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ld 260
           slp+ ++    + +l dc++ ftke+ l+g++k  c +c++++++ kk++++++P++L+lhLkRf  se++ + +k+++ v+fpl+ Ld
   Q: 443  SLPIAKRGYP-EVTLMDCMRLFTKEDVLDGDEKPTCCRCRARKRCIKKFSIQRFPKILVLHLKRF--SESRIRTSKLTTFVNFPLRdLD 528
           ******9976.779***************************************************..88899***************** PP
   S: 261  lspfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetgstaYvlfYk 336
           l++f +++++    +  Y+L+av +HsG++ +GHY+ay+++  +g+W +f+Ds+Vt+++ ++v +   s+aY+lfY+
   Q: 529  LREFASENTN----HAVYNLYAVSNHSGTTMGGHYTAYCRSpVTGEWHTFNDSSVTPMSSSQVRT---SDAYLLFYE 598
           ******9553....78*************************44666*******************...********8 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MSQLSSTLKR YTESARYTDA PYAKSGYGTY TPSSYGANLA ASFLEKEKLG FKPAPPTSLL 60
TRPRTYGPSS ILDYERGRTL LRPDIMGGGK RAESQTRSTE RPSGSGLSGG SGFPYGVTNN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCCAGC TCTCCTCCAC CCTGAAGCGC TACACGGAAT CAGCCCGCTA CACAGATGCC 60
CCTTACGCCA AATCGGGCTA TGGCACCTAC ACCCCCTCCT CCTATGGGGC CAACCTGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005938--C:cell cortex
GO:0005634--C:nucleus
GO:0048471--C:perinuclear region of cytoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0032922--P:circadian regulation of gene expression
GO:0043153--P:entrainment of circadian clock by photoperiod
GO:0045475--P:locomotor rhythm
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045931--P:positive regulation of mitotic cell cycle
GO:0016579--P:protein deubiquitination
GO:0050821--P:protein stabilization
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001988	Ailuropoda melanoleuca	94.22	0.00e+00	1093.00
IUUC-Aca-005132	Anolis carolinensis	59.97	0.00e+00	679.00
IUUC-Ame-011102	Astyanax mexicanus	75.22	2.00e-145	508.00
IUUC-Bta-012529	Bos taurus	92.24	0.00e+00	1028.00
IUUC-Bra-016678	Brassica rapa	35.76	3.00e-47	182.00
IUUC-Cja-019016	Callithrix jacchus	91.48	0.00e+00	1058.00
IUUC-Cfa-020714	Canis familiaris	94.22	0.00e+00	1121.00
IUUC-Cpo-021727	Cavia porcellus	90.92	0.00e+00	1040.00
IUUC-Csa-023071	Chlorocebus sabaeus	97.98	0.00e+00	681.00
IUUC-Cin-025797	Ciona intestinalis	50.43	1.00e-94	339.00
IUUC-Csv-026132	Ciona savignyi	50.43	7.00e-98	351.00
IUUC-Dre-027872	Danio rerio	81.23	3.00e-162	564.00
IUUC-Dno-029329	Dasypus novemcinctus	93.23	0.00e+00	1075.00
IUUC-Dor-030574	Dipodomys ordii	92.24	0.00e+00	1053.00
IUUC-Dme-032208	Drosophila melanogaster	46.59	2.00e-83	304.00
IUUC-Ete-032725	Echinops telfairi	81.84	8.00e-176	610.00
IUUC-Eca-033361	Equus caballus	95.38	0.00e+00	1109.00
IUUC-Eeu-035272	Erinaceus europaeus	78.93	0.00e+00	707.00
IUUC-Fca-036497	Felis catus	95.71	0.00e+00	1114.00
IUUC-Fal-036766	Ficedula albicollis	63.78	0.00e+00	685.00
IUUC-Gmo-039129	Gadus morhua	61.11	3.00e-122	431.00
IUUC-Gga-040889	Gallus gallus	83.83	5.00e-147	514.00
IUUC-Gac-042475	Gasterosteus aculeatus	69.54	9.00e-136	476.00
IUUC-Ggo-044814	Gorilla gorilla	92.53	2.00e-177	614.00
IUUC-Hsa-045937	Homo sapiens	93.23	0.00e+00	1051.00
IUUC-Itr-048171	Ictidomys tridecemlineatus	92.81	0.00e+00	1103.00
IUUC-Lch-050527	Latimeria chalumnae	60.28	5.00e-180	624.00
IUUC-Loc-052697	Lepisosteus oculatus	78.86	4.00e-161	561.00
IUUC-Laf-054167	Loxodonta africana	87.52	0.00e+00	1016.00
IUUC-Mcc-055584	Macaca mulatta	93.73	0.00e+00	1090.00
IUUC-Meu-056542	Macropus eugenii	85.83	0.00e+00	943.00
IUUC-Mga-060020	Meleagris gallopavo	59.49	0.00e+00	637.00
IUUC-Mmr-060989	Microcebus murinus	97.36	0.00e+00	1130.00
IUUC-Mdo-062761	Monodelphis domestica	85.50	0.00e+00	942.00
IUUC-Mmu-063710	Mus musculus	90.79	0.00e+00	1059.00
IUUC-Mpu-066573	Mustela putorius furo	95.05	0.00e+00	1105.00
IUUC-Nle-070013	Nomascus leucogenys	93.59	0.00e+00	1031.00
IUUC-Opr-070907	Ochotona princeps	91.10	0.00e+00	1016.00
IUUC-Ont-071944	Oreochromis niloticus	81.56	9.00e-164	569.00
IUUC-Oan-073105	Ornithorhynchus anatinus	79.35	3.00e-148	517.00
IUUC-Ocu-073941	Oryctolagus cuniculus	92.59	0.00e+00	1066.00
IUUC-Ola-087412	Oryzias latipes	71.53	1.00e-154	540.00
IUUC-Oar-089916	Ovis aries	92.74	0.00e+00	1076.00
IUUC-Ptr-090998	Pan troglodytes	93.56	0.00e+00	1059.00
IUUC-Pan-092686	Papio anubis	93.89	0.00e+00	1092.00
IUUC-Psi-093284	Pelodiscus sinensis	71.38	1.00e-123	435.00
IUUC-Pma-094462	Petromyzon marinus	65.24	7.00e-75	273.00
IUUC-Pno-094986	Phaeosphaeria nodorum	32.72	3.00e-39	157.00
IUUC-Pfo-097352	Poecilia formosa	78.93	7.00e-168	583.00
IUUC-Pab-098688	Pongo abelii	87.29	0.00e+00	949.00
IUUC-Pca-100205	Procavia capensis	93.66	0.00e+00	642.00
IUUC-Pva-103188	Pteropus vampyrus	94.72	0.00e+00	1064.00
IUUC-Rno-105853	Rattus norvegicus	91.91	0.00e+00	1103.00
IUUC-Sha-107237	Sarcophilus harrisii	85.34	0.00e+00	941.00
IUUC-Sar-113103	Sorex araneus	91.07	2.00e-180	624.00
IUUC-Ssc-115955	Sus scrofa	93.89	0.00e+00	1083.00
IUUC-Tgu-116894	Taeniopygia guttata	69.49	0.00e+00	625.00
IUUC-Tru-117703	Takifugu rubripes	66.08	1.00e-133	469.00
IUUC-Tsy-118879	Tarsius syrichta	96.86	0.00e+00	840.00
IUUC-Tni-119866	Tetraodon nigroviridis	78.30	1.00e-152	531.00
IUUC-Tbe-127367	Tupaia belangeri	86.08	0.00e+00	677.00
IUUC-Ttr-128773	Tursiops truncatus	90.76	0.00e+00	1065.00
IUUC-Vpa-130402	Vicugna pacos	83.80	0.00e+00	803.00
IUUC-Xtr-132658	Xenopus tropicalis	57.19	4.00e-179	620.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence