iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ncr-068869

Ensembl Protein ID

EAA31190

UniProt Accession

Q7S6N5; Q7S6N5_NEUCR

Genbank Protein ID

EAA31190.3

Protein Name

E3 ubiquitin-protein ligase

Genbank Nucleotide ID

CM002241

Gene Name

NCU04800

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
NCU04800	EAA31190	EAA31190

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	8.60e-83	277.5	767	1144

Active Site

Position(s)	Description	Evidence
1113	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 5    lkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknp.............ehlklFeflGrllgkalqdg 85
           lk+ ++v+f++     E+g+d gGvt+efl+ ++ e ++ + +lf++++++ +  +p     + n              ++lk++eflGr++gk++++g
   Q: 767  LKEPIQVTFEDefgmqEAGIDGGGVTKEFLDSVTTEAFTHT-ELFVTNSKNAYYPNPTLIDRIRNMrvgepeetqraveQVLKMYEFLGRIIGKCMYEG 864
           678899999999999999********************988.8***********9999999998889******************************** PP
   S: 86   rlldlplsksfyklllgk.....................klsledleevdpelykslkeikenaesdieelgldltfs.vseeilgetkeee..LkpgG 160
            l+d+ ++ +f+ +  +                      + +++dl e+d+ely+ + ++k++  +  ++l+ld+t++ + ++  + t++    L+p G
   Q: 865  ILIDIVFAGFFLLKWATAndtpgggsnplassssttagyRANINDLRELDEELYQGMLSLKNYTGDVQTDLALDFTITdPINSPGEPTRTIIrpLIPHG 963
           ************99955544444444444444444445479**********************8777778888888886555554444444357***** PP
   S: 161  enipVtneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggyt.....edspaiqwFwevl 253
           +++pVtneN+  Y++ v+ +rl ++   q+ af +G+ +vi++++ls+F++ el+ l+ G+ +eidvedl+++t y+g y+     e++p+iq Fwev+
   Q: 964  DSTPVTNENRPLYISYVARHRLVRQPYPQTRAFLRGLGSVIDPSWLSMFNQLELQRLVGGDsSEIDVEDLRRNTHYNGVYQigldgEEHPTIQIFWEVM 1062
           **************************************************************************99666654444589*********** PP
   S: 254  eefsseerkafLqFvTgssrlPlgGfaelkprlfvirkdasd.drlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           +e+++eer++ L++vT+++r+Pl Gf +l+p  f+ir++++d drlPs++TC+n+LkLP+Y sk  lkekLlyA+++++gF+l
   Q: 1063 HELKDEERREVLKYVTSTPRAPLLGFGQLRPY-FTIRDAGQDeDRLPSASTCVNLLKLPQYRSKGRLKEKLLYAVKSGAGFNL 1144
           ******************************77.9999977776**************************************98 PP

Organism

Neurospora crassa

Protein Sequence
(Fasta)

MFPTFTGSSR KGRNVNLSGQ RTSNPFTSTS WGAGSATGAS KTVAHAQAER QQRQQERDRL 60
RAAQRIQRTW RGHRVRRTLR DEQRQAIDRL YEAQPVDAGQ RSAQALPLVF AAFQAFNVQD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACGGGGACA TCAACCACAC CGTTCACGAC GACCAACTGC AAGACAACAC CTCCAGCGCG 60
GAGATCCCGG CTCGTACGAC CTCCTAGTTC AAGTCCGAAT ATCTACACCG CATCAGAACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

KEGG

ncr:NCU04800

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	35.57	3.00e-86	311.00
IUUC-Aml-001355	Ailuropoda melanoleuca	35.96	6.00e-82	297.00
IUUC-Atr-003017	Amborella trichopoda	36.02	2.00e-85	309.00
IUUC-Apl-003731	Anas platyrhynchos	35.26	4.00e-84	304.00
IUUC-Aca-005248	Anolis carolinensis	34.68	7.00e-83	300.00
IUUC-Aly-005794	Arabidopsis lyrata	35.03	2.00e-82	299.00
IUUC-Ath-007269	Arabidopsis thaliana	36.08	1.00e-86	313.00
IUUC-Ago-007748	Ashbya gossypii	34.63	3.00e-75	274.00
IUUC-Acl-008158	Aspergillus clavatus	43.47	0.00e+00	669.00
IUUC-Afl-008398	Aspergillus flavus	40.53	0.00e+00	699.00
IUUC-Afu-008937	Aspergillus fumigatus	44.55	0.00e+00	677.00
IUUC-Ani-009252	Aspergillus nidulans	41.21	0.00e+00	750.00
IUUC-Ang-009773	Aspergillus niger	40.66	0.00e+00	693.00
IUUC-Aor-009940	Aspergillus oryzae	40.14	0.00e+00	699.00
IUUC-Ate-010395	Aspergillus terreus	44.60	0.00e+00	679.00
IUUC-Ame-010769	Astyanax mexicanus	34.76	2.00e-57	216.00
IUUC-Bgr-012269	Blumeria graminis	60.00	2.00e-154	536.00
IUUC-Bta-012841	Bos taurus	36.19	5.00e-85	307.00
IUUC-Bci-013743	Botrytis cinerea	46.18	0.00e+00	799.00
IUUC-Bdi-014502	Brachypodium distachyon	36.36	4.00e-89	321.00
IUUC-Bol-015093	Brassica oleracea	36.08	3.00e-87	315.00
IUUC-Bra-016722	Brassica rapa	36.25	7.00e-88	317.00
IUUC-Cel-018447	Caenorhabditis elegans	33.13	9.00e-63	233.00
IUUC-Cja-019743	Callithrix jacchus	35.34	2.00e-80	292.00
IUUC-Cfa-021031	Canis familiaris	35.79	4.00e-82	298.00
IUUC-Cpo-022401	Cavia porcellus	35.96	2.00e-83	302.00
IUUC-Cre-022725	Chlamydomonas reinhardtii	34.25	4.00e-64	236.00
IUUC-Csa-024107	Chlorocebus sabaeus	35.44	4.00e-81	295.00
IUUC-Cho-024750	Choloepus hoffmanni	40.26	3.00e-71	261.00
IUUC-Cin-025750	Ciona intestinalis	33.27	1.00e-60	226.00
IUUC-Csv-026016	Ciona savignyi	31.99	3.00e-68	251.00
IUUC-Cgl-026559	Colletotrichum gloeosporioides	47.07	0.00e+00	947.00
IUUC-Cne-026841	Cryptococcus neoformans	33.53	2.00e-89	322.00
IUUC-Cme-027265	Cyanidioschyzon merolae	40.43	1.00e-84	305.00
IUUC-Dre-028196	Danio rerio	36.67	7.00e-86	310.00
IUUC-Dno-029024	Dasypus novemcinctus	35.96	5.00e-83	300.00
IUUC-Dor-030938	Dipodomys ordii	36.77	2.00e-66	246.00
IUUC-Dse-031416	Dothistroma septosporum	38.87	0.00e+00	665.00
IUUC-Dme-031946	Drosophila melanogaster	38.88	5.00e-78	284.00
IUUC-Ete-033041	Echinops telfairi	33.71	3.00e-46	179.00
IUUC-Eca-033828	Equus caballus	35.61	2.00e-82	299.00
IUUC-Eeu-035201	Erinaceus europaeus	32.87	7.00e-44	171.00
IUUC-Fca-035907	Felis catus	35.79	4.00e-82	298.00
IUUC-Fal-037389	Ficedula albicollis	35.26	9.00e-84	303.00
IUUC-Fox-037788	Fusarium oxysporum	46.71	0.00e+00	776.00
IUUC-Fso-038088	Fusarium solani	44.68	0.00e+00	829.00
IUUC-Gmo-039412	Gadus morhua	32.01	1.00e-68	253.00
IUUC-Ggr-039941	Gaeumannomyces graminis	48.54	0.00e+00	949.00
IUUC-Gga-040310	Gallus gallus	35.09	1.00e-83	303.00
IUUC-Gac-042088	Gasterosteus aculeatus	32.53	9.00e-71	260.00
IUUC-Gma-042728	Glycine max	36.19	2.00e-85	309.00
IUUC-Ggo-045031	Gorilla gorilla	35.61	1.00e-81	296.00
IUUC-Hsa-045880	Homo sapiens	35.61	1.00e-81	296.00
IUUC-Hvu-047102	Hordeum vulgare	35.16	2.00e-84	305.00
IUUC-Itr-048372	Ictidomys tridecemlineatus	37.00	3.00e-67	246.00
IUUC-Kpa-049307	Komagataella pastoris	31.91	3.00e-79	288.00
IUUC-Lch-050664	Latimeria chalumnae	32.30	6.00e-72	264.00
IUUC-Lpe-050755	Leersia perrieri	39.04	2.00e-85	308.00
IUUC-Loc-052218	Lepisosteus oculatus	36.01	1.00e-85	309.00
IUUC-Lma-053096	Leptosphaeria maculans	40.87	0.00e+00	733.00
IUUC-Laf-053902	Loxodonta africana	32.24	4.00e-71	261.00
IUUC-Mcc-055127	Macaca mulatta	35.61	1.00e-81	296.00
IUUC-Meu-056527	Macropus eugenii	37.31	5.00e-55	207.00
IUUC-Mor-057021	Magnaporthe oryzae	47.83	0.00e+00	961.00
IUUC-Mpo-057570	Magnaporthe poae	47.66	0.00e+00	902.00
IUUC-Mtr-057671	Medicago truncatula	35.49	4.00e-84	305.00
IUUC-Mla-059124	Melampsora laricipopulina	42.16	1.00e-101	361.00
IUUC-Mga-059581	Meleagris gallopavo	35.09	1.00e-83	303.00
IUUC-Mvi-060445	Microbotryum violaceum	34.77	8.00e-115	406.00
IUUC-Mmr-061360	Microcebus murinus	35.79	5.00e-82	297.00
IUUC-Mdo-062194	Monodelphis domestica	35.61	1.00e-84	306.00
IUUC-Mmu-064189	Mus musculus	35.61	2.00e-82	299.00
IUUC-Mac-064989	Musa acuminata	35.92	9.00e-85	306.00
IUUC-Mpu-066439	Mustela putorius furo	35.44	6.00e-82	297.00
IUUC-Mlu-068228	Myotis lucifugus	35.96	6.00e-83	300.00
IUUC-Nfi-068280	Neosartorya fischeri	40.40	0.00e+00	697.00
IUUC-Nle-069687	Nomascus leucogenys	35.33	4.00e-81	294.00
IUUC-Opr-070554	Ochotona princeps	32.76	3.00e-71	261.00
IUUC-Ont-071836	Oreochromis niloticus	35.96	3.00e-85	308.00
IUUC-Oan-072800	Ornithorhynchus anatinus	35.61	1.00e-83	303.00
IUUC-Ocu-074587	Oryctolagus cuniculus	35.96	3.00e-83	301.00
IUUC-Oba-075213	Oryza barthii	35.74	4.00e-87	314.00
IUUC-Obr-076320	Oryza brachyantha	32.85	2.00e-88	318.00
IUUC-Ogl-077093	Oryza glaberrima	35.91	2.00e-88	319.00
IUUC-Ogu-078947	Oryza glumaepatula	39.45	6.00e-82	297.00
IUUC-Oin-080058	Oryza indica	39.92	3.00e-86	311.00
IUUC-Olo-080742	Oryza longistaminata	39.58	2.00e-86	312.00
IUUC-Ome-081741	Oryza meridionalis	34.71	4.00e-81	294.00
IUUC-Oni-082385	Oryza nivara	39.45	5.00e-82	297.00
IUUC-Opu-083529	Oryza punctata	36.08	2.00e-88	319.00
IUUC-Oru-085128	Oryza rufipogon	38.96	2.00e-76	279.00
IUUC-Osa-085557	Oryza sativa	39.54	6.00e-86	310.00
IUUC-Ola-087209	Oryzias latipes	36.14	2.00e-85	308.00
IUUC-Olu-087699	Ostreococcus lucimarinus	37.71	2.00e-68	251.00
IUUC-Oga-088776	Otolemur garnettii	36.14	3.00e-83	301.00
IUUC-Oar-089441	Ovis aries	36.19	4.00e-85	307.00
IUUC-Ptr-091273	Pan troglodytes	35.61	1.00e-81	296.00
IUUC-Pan-091981	Papio anubis	35.61	1.00e-81	296.00
IUUC-Psi-093251	Pelodiscus sinensis	31.65	3.00e-61	228.00
IUUC-Pma-094738	Petromyzon marinus	34.25	1.00e-80	293.00
IUUC-Pno-095132	Phaeosphaeria nodorum	45.01	5.00e-173	599.00
IUUC-Ppa-095867	Physcomitrella patens	35.95	2.00e-85	309.00
IUUC-Pfo-097511	Poecilia formosa	36.32	1.00e-86	313.00
IUUC-Pab-098570	Pongo abelii	32.76	5.00e-71	261.00
IUUC-Pop-098928	Populus trichocarpa	38.54	3.00e-70	258.00
IUUC-Pca-100987	Procavia capensis	40.15	9.00e-74	270.00
IUUC-Ppe-101281	Prunus persica	35.25	2.00e-84	305.00
IUUC-Pva-103034	Pteropus vampyrus	33.33	2.00e-71	262.00
IUUC-Pgr-103513	Puccinia graminis	40.80	3.00e-110	391.00
IUUC-Ptt-103967	Puccinia triticina	41.88	4.00e-100	357.00
IUUC-Pte-104105	Pyrenophora teres	47.67	0.00e+00	714.00
IUUC-Pyt-104449	Pyrenophora triticirepentis	47.09	0.00e+00	702.00
IUUC-Rno-106028	Rattus norvegicus	29.83	2.00e-54	206.00
IUUC-Sce-106446	Saccharomyces cerevisiae	42.03	1.00e-84	306.00
IUUC-Sha-107108	Sarcophilus harrisii	34.15	6.00e-75	274.00
IUUC-Sja-107889	Schizosaccharomyces japonicus	36.57	2.00e-92	332.00
IUUC-Spo-108097	Schizosaccharomyces pombe	39.05	2.00e-100	358.00
IUUC-Ssl-108520	Sclerotinia sclerotiorum	43.48	0.00e+00	841.00
IUUC-Smo-109537	Selaginella moellendorffii	40.13	1.00e-84	306.00
IUUC-Sit-109811	Setaria italica	39.67	3.00e-85	308.00
IUUC-Sly-111362	Solanum lycopersicum	40.04	9.00e-77	280.00
IUUC-Sar-113687	Sorex araneus	34.52	7.00e-42	164.00
IUUC-Sbi-114433	Sorghum bicolor	36.14	2.00e-86	312.00
IUUC-Sre-115038	Sporisorium reilianum	42.37	7.00e-94	337.00
IUUC-Ssc-116103	Sus scrofa	32.59	8.00e-71	260.00
IUUC-Tgu-116729	Taeniopygia guttata	35.26	4.00e-84	304.00
IUUC-Tru-118068	Takifugu rubripes	35.80	5.00e-83	301.00
IUUC-Tsy-118942	Tarsius syrichta	41.75	4.00e-55	208.00
IUUC-Tni-120732	Tetraodon nigroviridis	35.63	3.00e-80	291.00
IUUC-Tca-121770	Theobroma cacao	35.96	1.00e-84	306.00
IUUC-Tre-121892	Trichoderma reesei	43.37	0.00e+00	834.00
IUUC-Tvi-122354	Trichoderma virens	43.56	0.00e+00	864.00
IUUC-Tae-125229	Triticum aestivum	38.76	2.00e-80	292.00
IUUC-Tur-126086	Triticum urartu	35.57	4.00e-86	311.00
IUUC-Tme-127102	Tuber melanosporum	45.49	0.00e+00	643.00
IUUC-Tbe-127351	Tupaia belangeri	33.72	2.00e-62	232.00
IUUC-Ttr-129061	Tursiops truncatus	40.15	5.00e-74	271.00
IUUC-Uma-129343	Ustilago maydis	34.66	2.00e-109	388.00
IUUC-Vda-129748	Verticillium dahliae	48.83	0.00e+00	738.00
IUUC-Vvi-131524	Vitis vinifera	35.32	1.00e-82	300.00
IUUC-Xtr-132094	Xenopus tropicalis	35.09	6.00e-82	297.00
IUUC-Xma-133923	Xiphophorus maculatus	36.32	1.00e-86	313.00
IUUC-Yli-134496	Yarrowia lipolytica	38.83	7.00e-91	326.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence