iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Csv-026016

UUCD1 version

UUC-CiS-00375

Ensembl Protein ID

ENSCSAVP00000012703.1

UniProt Accession

H2Z541; H2Z541_CIOSA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAVG00000007461.1	ENSCSAVT00000012851.1	ENSCSAVP00000012703.1
ENSCSAVG00000007461.1	ENSCSAVT00000012852.1	ENSCSAVP00000012704.1
ENSCSAVG00000007461.1	ENSCSAVT00000012853.1	ENSCSAVP00000012705.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	3.40e-102	342.3	705	1075

Active Site

Position(s)	Description	Evidence
1043	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalq 83
           ++lk +++v+f +     E+g+d++Gv++efl++++ +++npd++lf+ +++++  l+p+p s l++ +hl lF+f+G++lgka++
   Q: 705  NSLKGVIRVKFINdlgldEAGIDQDGVFKEFLEEIITKVFNPDMNLFKVTAGGDMKLYPSPLSHLQD-QHLLLFNFVGKILGKAIY 789
           67999***********************************************************976.****************** PP
   S: 84   dgrlldlplsksfyklllgk.....klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenip 164
           +g +ld+p++++f++ l g+        +++l+++dpe+yk+l++ik++ e di++  ldltf+ +e+i+g+++++eL+pgG+ +p
   Q: 790  EGIVLDIPFANFFLRNLQGQqhtalYSPIDELPSLDPEFYKNLTWIKRY-EGDISD--LDLTFTYEEDIMGSVHSHELIPGGAATP 872
           *******************9666544667********************.667877..68888889******************** PP
   S: 165  VtneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwF 249
           VtneN+ +Y++ +++yrl+++i +q++af +Gf+ vip+++ s+F++ el+ li+G+  ++d+ dlkk+  y gg+++++++++w+
   Q: 873  VTNENRIMYIHTLAHYRLHTQILQQTKAFISGFRAVIPKSWTSMFSAPELQRLISGDnVDVDLTDLKKHVVYYGGFHSTHRVVRWL 958
           *********************************************************99*************************** PP
   S: 250  wevl.eefsseerkafLqFvTgssrlPlgGfaelk........................prlfvirk...........dasddrlP 299
           w++l ++ ss er+afL+FvT++sr Pl Gf  l+                        +                   + ++rlP
   Q: 959  WDILeRDYSSSERSAFLKFVTSCSRPPLLGFVHLQpqfsircvevpddedtgdtvatvlR------GflrlpsksrraHNYNHRLP 1038
           ****889****************************7777777777777777765555551......1555555666656777**** PP
   S: 300  ssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           +++TCfn+LkLP+Y+sk++l++kL  Ai +++gFels
   Q: 1039 TASTCFNLLKLPNYPSKDVLRDKLKQAIANNTGFELS 1075
           **********************************985 PP

Organism

Ciona savignyi

Protein Sequence
(Fasta)

MFSTNSVKTG QDLVKNARQA REDRALSKRQ ESAAIILQCL ARGFLARSRL SKRWRYELDQ 60
LIGWDSKMTE ISSSEMFLII KKFMFVFNFK TDKLRFGELC KYLVHNTETN DNAKTCYIGL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTTTCAA CCAATTCGGT AAAGACAGGT CAAGACTTGG TCAAAAATGC TCGCCAAGCA 60
CGTGAAGACC GAGCACTGTC AAAGCGACAG GAGAGTGCAG CAATTATTCT ACAATGTTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	37.17	1.00e-98	353.00
IUUC-Aml-002107	Ailuropoda melanoleuca	47.53	0.00e+00	995.00
IUUC-Atr-003017	Amborella trichopoda	36.22	3.00e-104	372.00
IUUC-Apl-003328	Anas platyrhynchos	48.21	0.00e+00	951.00
IUUC-Aca-005248	Anolis carolinensis	35.14	1.00e-92	333.00
IUUC-Aly-005768	Arabidopsis lyrata	35.40	7.00e-104	370.00
IUUC-Ath-006576	Arabidopsis thaliana	35.07	5.00e-103	367.00
IUUC-Ago-007748	Ashbya gossypii	36.44	5.00e-66	244.00
IUUC-Acl-008158	Aspergillus clavatus	33.87	2.00e-62	233.00
IUUC-Afl-008398	Aspergillus flavus	32.93	3.00e-63	235.00
IUUC-Afu-008937	Aspergillus fumigatus	33.47	3.00e-63	235.00
IUUC-Ani-009252	Aspergillus nidulans	33.87	3.00e-69	255.00
IUUC-Ang-009773	Aspergillus niger	33.53	2.00e-65	243.00
IUUC-Aor-009940	Aspergillus oryzae	32.93	4.00e-63	235.00
IUUC-Ate-010395	Aspergillus terreus	33.87	1.00e-64	240.00
IUUC-Ame-010769	Astyanax mexicanus	36.45	1.00e-61	229.00
IUUC-Bgr-012269	Blumeria graminis	34.42	4.00e-60	223.00
IUUC-Bta-013547	Bos taurus	47.95	0.00e+00	1009.00
IUUC-Bci-013743	Botrytis cinerea	34.61	3.00e-70	258.00
IUUC-Bdi-014502	Brachypodium distachyon	37.28	3.00e-103	368.00
IUUC-Bol-015093	Brassica oleracea	37.57	1.00e-102	366.00
IUUC-Bra-016722	Brassica rapa	38.57	1.00e-104	373.00
IUUC-Cel-018447	Caenorhabditis elegans	38.04	1.00e-170	592.00
IUUC-Cja-019855	Callithrix jacchus	47.29	0.00e+00	990.00
IUUC-Cfa-020066	Canis familiaris	47.40	0.00e+00	981.00
IUUC-Cpo-021504	Cavia porcellus	48.04	0.00e+00	1021.00
IUUC-Cre-022673	Chlamydomonas reinhardtii	36.24	1.00e-73	270.00
IUUC-Csa-023579	Chlorocebus sabaeus	48.13	0.00e+00	1000.00
IUUC-Cho-024430	Choloepus hoffmanni	39.04	0.00e+00	629.00
IUUC-Cin-025750	Ciona intestinalis	71.05	0.00e+00	1520.00
IUUC-Cgl-026559	Colletotrichum gloeosporioides	34.18	1.00e-69	256.00
IUUC-Cne-026841	Cryptococcus neoformans	32.30	2.00e-70	259.00
IUUC-Cme-027265	Cyanidioschyzon merolae	39.91	8.00e-89	320.00
IUUC-Dre-028271	Danio rerio	46.53	0.00e+00	942.00
IUUC-Dno-029054	Dasypus novemcinctus	47.76	0.00e+00	998.00
IUUC-Dor-030938	Dipodomys ordii	55.80	0.00e+00	726.00
IUUC-Dse-031416	Dothistroma septosporum	34.00	1.00e-65	243.00
IUUC-Dme-031602	Drosophila melanogaster	39.74	0.00e+00	747.00
IUUC-Ete-033041	Echinops telfairi	50.00	8.00e-158	549.00
IUUC-Eca-034411	Equus caballus	47.67	0.00e+00	982.00
IUUC-Eeu-035201	Erinaceus europaeus	55.25	9.00e-154	536.00
IUUC-Fca-036594	Felis catus	47.44	0.00e+00	971.00
IUUC-Fal-037317	Ficedula albicollis	46.62	0.00e+00	947.00
IUUC-Fox-037788	Fusarium oxysporum	30.31	4.00e-72	265.00
IUUC-Fso-038088	Fusarium solani	33.19	2.00e-69	256.00
IUUC-Gmo-039412	Gadus morhua	45.86	0.00e+00	966.00
IUUC-Ggr-039941	Gaeumannomyces graminis	34.29	3.00e-72	265.00
IUUC-Gga-040149	Gallus gallus	48.05	0.00e+00	966.00
IUUC-Gac-042088	Gasterosteus aculeatus	46.83	0.00e+00	1003.00
IUUC-Gma-043839	Glycine max	36.99	5.00e-104	370.00
IUUC-Ggo-045279	Gorilla gorilla	47.85	0.00e+00	995.00
IUUC-Hsa-045660	Homo sapiens	47.57	0.00e+00	995.00
IUUC-Hvu-047770	Hordeum vulgare	35.47	1.00e-105	375.00
IUUC-Itr-048372	Ictidomys tridecemlineatus	65.09	5.00e-168	582.00
IUUC-Kpa-049307	Komagataella pastoris	35.12	6.00e-62	231.00
IUUC-Lch-050664	Latimeria chalumnae	47.33	0.00e+00	993.00
IUUC-Lpe-051428	Leersia perrieri	32.84	5.00e-93	334.00
IUUC-Loc-052791	Lepisosteus oculatus	47.39	0.00e+00	964.00
IUUC-Lma-053096	Leptosphaeria maculans	36.99	3.00e-69	255.00
IUUC-Laf-053902	Loxodonta africana	47.39	0.00e+00	998.00
IUUC-Mcc-054730	Macaca mulatta	48.13	0.00e+00	1000.00
IUUC-Meu-056527	Macropus eugenii	42.92	0.00e+00	829.00
IUUC-Mor-057021	Magnaporthe oryzae	34.22	8.00e-62	231.00
IUUC-Mpo-057570	Magnaporthe poae	35.05	4.00e-71	261.00
IUUC-Mtr-057671	Medicago truncatula	38.05	5.00e-108	384.00
IUUC-Mla-059124	Melampsora laricipopulina	38.04	1.00e-78	285.00
IUUC-Mga-059260	Meleagris gallopavo	48.00	0.00e+00	970.00
IUUC-Mvi-060445	Microbotryum violaceum	33.55	1.00e-89	323.00
IUUC-Mmr-060804	Microcebus murinus	47.06	0.00e+00	961.00
IUUC-Mdo-062575	Monodelphis domestica	46.35	0.00e+00	938.00
IUUC-Mmu-063636	Mus musculus	46.00	0.00e+00	956.00
IUUC-Mac-064989	Musa acuminata	37.74	3.00e-104	372.00
IUUC-Mpu-066677	Mustela putorius furo	47.16	0.00e+00	927.00
IUUC-Mlu-067952	Myotis lucifugus	48.14	0.00e+00	964.00
IUUC-Nfi-068280	Neosartorya fischeri	33.47	2.00e-63	236.00
IUUC-Ncr-068869	Neurospora crassa	31.99	5.00e-68	251.00
IUUC-Nle-069153	Nomascus leucogenys	47.77	0.00e+00	997.00
IUUC-Opr-070554	Ochotona princeps	47.99	0.00e+00	937.00
IUUC-Ont-071372	Oreochromis niloticus	46.74	0.00e+00	979.00
IUUC-Oan-072800	Ornithorhynchus anatinus	35.14	5.00e-92	330.00
IUUC-Ocu-074183	Oryctolagus cuniculus	47.67	0.00e+00	990.00
IUUC-Oba-075006	Oryza barthii	36.24	7.00e-107	380.00
IUUC-Obr-076133	Oryza brachyantha	36.24	1.00e-106	379.00
IUUC-Ogl-077003	Oryza glaberrima	36.24	8.00e-107	380.00
IUUC-Ogu-078947	Oryza glumaepatula	36.34	5.00e-106	377.00
IUUC-Oin-080058	Oryza indica	37.90	5.00e-103	367.00
IUUC-Olo-080475	Oryza longistaminata	35.83	7.00e-107	380.00
IUUC-Ome-081741	Oryza meridionalis	37.46	1.00e-97	349.00
IUUC-Oni-082385	Oryza nivara	36.34	5.00e-106	377.00
IUUC-Opu-083176	Oryza punctata	36.32	6.00e-104	370.00
IUUC-Oru-084554	Oryza rufipogon	34.10	4.00e-93	335.00
IUUC-Osa-085355	Oryza sativa	36.24	1.00e-106	379.00
IUUC-Ola-087337	Oryzias latipes	47.05	0.00e+00	954.00
IUUC-Olu-087699	Ostreococcus lucimarinus	40.90	1.00e-80	291.00
IUUC-Oga-088342	Otolemur garnettii	47.40	0.00e+00	949.00
IUUC-Oar-090234	Ovis aries	47.69	0.00e+00	993.00
IUUC-Ptr-091661	Pan troglodytes	47.85	0.00e+00	996.00
IUUC-Pan-092728	Papio anubis	47.72	0.00e+00	996.00
IUUC-Psi-093251	Pelodiscus sinensis	47.30	0.00e+00	884.00
IUUC-Pma-094195	Petromyzon marinus	44.97	0.00e+00	889.00
IUUC-Pno-095132	Phaeosphaeria nodorum	34.00	3.00e-52	198.00
IUUC-Ppa-095682	Physcomitrella patens	35.81	1.00e-108	386.00
IUUC-Pfo-097472	Poecilia formosa	46.69	0.00e+00	984.00
IUUC-Pab-098570	Pongo abelii	47.95	0.00e+00	999.00
IUUC-Pop-098928	Populus trichocarpa	35.83	3.00e-97	348.00
IUUC-Pca-100110	Procavia capensis	57.53	0.00e+00	653.00
IUUC-Ppe-101281	Prunus persica	38.37	3.00e-106	378.00
IUUC-Pva-102887	Pteropus vampyrus	45.95	0.00e+00	923.00
IUUC-Pgr-103513	Puccinia graminis	34.25	1.00e-78	286.00
IUUC-Ptt-103967	Puccinia triticina	32.17	7.00e-70	257.00
IUUC-Pte-104105	Pyrenophora teres	34.08	2.00e-66	246.00
IUUC-Pyt-104449	Pyrenophora triticirepentis	34.08	2.00e-66	246.00
IUUC-Rno-106028	Rattus norvegicus	44.55	0.00e+00	878.00
IUUC-Sce-106446	Saccharomyces cerevisiae	30.08	5.00e-57	214.00
IUUC-Sha-107331	Sarcophilus harrisii	47.30	0.00e+00	946.00
IUUC-Sja-107889	Schizosaccharomyces japonicus	38.50	1.00e-77	283.00
IUUC-Spo-108097	Schizosaccharomyces pombe	33.50	3.00e-79	288.00
IUUC-Ssl-108520	Sclerotinia sclerotiorum	33.33	2.00e-66	245.00
IUUC-Smo-109537	Selaginella moellendorffii	39.29	3.00e-108	385.00
IUUC-Sit-109811	Setaria italica	37.07	7.00e-105	374.00
IUUC-Sly-111362	Solanum lycopersicum	36.66	3.00e-100	358.00
IUUC-Sar-113287	Sorex araneus	56.00	2.00e-103	369.00
IUUC-Sbi-114433	Sorghum bicolor	36.38	4.00e-103	367.00
IUUC-Sre-115038	Sporisorium reilianum	39.50	6.00e-81	294.00
IUUC-Ssc-116103	Sus scrofa	47.72	0.00e+00	979.00
IUUC-Tgu-117275	Taeniopygia guttata	47.57	0.00e+00	963.00
IUUC-Tru-118681	Takifugu rubripes	46.63	0.00e+00	1001.00
IUUC-Tsy-118985	Tarsius syrichta	34.03	5.00e-93	334.00
IUUC-Tni-120850	Tetraodon nigroviridis	66.17	4.00e-165	572.00
IUUC-Tca-121770	Theobroma cacao	39.25	4.00e-109	387.00
IUUC-Tre-121892	Trichoderma reesei	34.14	1.00e-74	273.00
IUUC-Tvi-122354	Trichoderma virens	35.08	2.00e-75	275.00
IUUC-Tae-125466	Triticum aestivum	35.47	8.00e-106	376.00
IUUC-Tur-126086	Triticum urartu	37.17	1.00e-98	353.00
IUUC-Tme-127102	Tuber melanosporum	34.54	7.00e-70	257.00
IUUC-Tbe-127461	Tupaia belangeri	44.57	0.00e+00	855.00
IUUC-Ttr-129269	Tursiops truncatus	47.17	0.00e+00	961.00
IUUC-Uma-129343	Ustilago maydis	38.58	1.00e-81	296.00
IUUC-Vda-129748	Verticillium dahliae	33.06	1.00e-62	233.00
IUUC-Vpa-130523	Vicugna pacos	69.86	2.00e-63	236.00
IUUC-Vvi-131524	Vitis vinifera	38.75	4.00e-108	384.00
IUUC-Xtr-132146	Xenopus tropicalis	46.92	0.00e+00	987.00
IUUC-Xma-133526	Xiphophorus maculatus	46.69	0.00e+00	981.00
IUUC-Yli-134496	Yarrowia lipolytica	35.85	7.00e-74	270.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence