iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pma-094195

UUCD1 version

UUC-PeM-00425

Ensembl Protein ID

ENSPMAP00000004296.1

UniProt Accession

S4RGG4; S4RGG4_PETMA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPMAG00000003915.1	ENSPMAT00000004313.1	ENSPMAP00000004296.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.00e-104	349.8	716	1080

Active Site

Position(s)	Description	Evidence
1048	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqd 84
           ++lk  ++v+f +     E+g+d++Gv++efl++++k++++p+l+lf+ + +d++ l+p+p+s++++ +hl+l ef+G++lgka+++
   Q: 716  NSLKGTIRVKFINdlgmdEAGIDQDGVFKEFLEEIIKKVFDPELNLFKITIGDER-LYPSPTSYVHE-NHLQLMEFVGKMLGKAVYE 800
           578999*****************************************99987665.59*******76.******************* PP
   S: 85   grlldlplsksfyklllgk.....klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVt 166
           g ++d+p++++f++++ g+       s+++l+++d+e+yk+l++ik++ + d++e  l ltfs +e+i+g+  ++eL+pgG+++ Vt
   Q: 801  GIVVDVPFAPFFLSQVRGVhtsmpYSSIDELPSLDAEFYKNLTSIKRY-DGDVSE--LGLTFSYEEDIMGKLVCYELCPGGKTTLVT 884
           ****************999777755778********************.567777..57777788********************** PP
   S: 167  neNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwev 252
           neNk +Y++ ++++r+  +ik+q+ af  Gf+++i++e++ +F++ e++ li G+  eid+edl+k+t y gg+++++++i+w+w++
   Q: 885  NENKISYIHMLAHHRMYVKIKKQTGAFIHGFKSLISPEWMGMFSTPEMQRLIAGDtGEIDFEDLRKHTVYYGGFHNNHRVIIWLWDI 971
           *************************************************************************************** PP
   S: 253  l.eefsseerkafLqFvTgssrlPlgGfaelk........................prlfvirkdasddrlPssnTCfnyLkLPeYs 314
           l +ef+++er++fL+FvT++sr Pl Gfa lk                        + +f+irk++   rlP+s+TCfn+LkLP+Ys
   Q: 972  LtKEFTAQERAMFLKFVTSCSRPPLLGFAHLKpsfsircvevaddqdtgdtlgsvlRGFFTIRKKEPAGRLPTSSTCFNLLKLPNYS 1058
           *9**************************************************************9999******************* PP
   S: 315  skeilkekLlyAieetkgFels 336
           +k++l++kL+yA+++++gFels
   Q: 1059 KKSVLRDKLRYAVSMNTGFELS 1080
           *******************985 PP

Organism

Petromyzon marinus

Protein Sequence
(Fasta)

MFGAGAQSQS TRAEFLDRAR VAREERRGQR DRERAAIKIQ ALVRGFLCRR CIARRTRHEV 60
DEFFSAQEAS PAKKNALCLF KIGQKLLFIF NTAEDIKRFE KFCRHLLSSM EEDNDSKVWY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTCGGCG CGGGCGCCCA GAGCCAAAGC ACTCGTGCCG AGTTCCTGGA CCGAGCGCGT 60
GTGGCGCGGG AGGAGCGGCG AGGCCAGCGG GATCGAGAGC GTGCCGCCAT CAAGATCCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT
PF00612--IQ

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	37.88	9.00e-105	374.00
IUUC-Aml-002107	Ailuropoda melanoleuca	70.20	0.00e+00	1513.00
IUUC-Atr-003017	Amborella trichopoda	39.08	1.00e-112	400.00
IUUC-Apl-003328	Anas platyrhynchos	70.08	0.00e+00	1481.00
IUUC-Aly-005794	Arabidopsis lyrata	38.94	4.00e-106	378.00
IUUC-Ath-007269	Arabidopsis thaliana	39.65	9.00e-111	393.00
IUUC-Bta-013547	Bos taurus	70.30	0.00e+00	1549.00
IUUC-Bdi-014502	Brachypodium distachyon	38.87	6.00e-108	384.00
IUUC-Bol-015093	Brassica oleracea	39.97	3.00e-112	398.00
IUUC-Bra-016722	Brassica rapa	40.14	1.00e-112	399.00
IUUC-Cel-018447	Caenorhabditis elegans	38.35	0.00e+00	686.00
IUUC-Cja-019855	Callithrix jacchus	69.74	0.00e+00	1507.00
IUUC-Cfa-020066	Canis familiaris	69.82	0.00e+00	1496.00
IUUC-Cpo-021504	Cavia porcellus	69.55	0.00e+00	1536.00
IUUC-Csa-023579	Chlorocebus sabaeus	69.74	0.00e+00	1504.00
IUUC-Cho-024430	Choloepus hoffmanni	59.98	0.00e+00	1053.00
IUUC-Cin-025750	Ciona intestinalis	45.35	0.00e+00	900.00
IUUC-Csv-026016	Ciona savignyi	45.98	0.00e+00	952.00
IUUC-Dre-028271	Danio rerio	69.94	0.00e+00	1497.00
IUUC-Dno-029054	Dasypus novemcinctus	70.02	0.00e+00	1518.00
IUUC-Dor-030938	Dipodomys ordii	74.03	0.00e+00	962.00
IUUC-Dme-031602	Drosophila melanogaster	44.90	0.00e+00	906.00
IUUC-Ete-033041	Echinops telfairi	66.32	0.00e+00	736.00
IUUC-Eca-034411	Equus caballus	70.20	0.00e+00	1502.00
IUUC-Eeu-035201	Erinaceus europaeus	66.60	0.00e+00	655.00
IUUC-Fca-036594	Felis catus	70.11	0.00e+00	1504.00
IUUC-Fal-037317	Ficedula albicollis	67.29	0.00e+00	1484.00
IUUC-Gmo-039412	Gadus morhua	67.41	0.00e+00	1494.00
IUUC-Gga-040149	Gallus gallus	70.03	0.00e+00	1508.00
IUUC-Gac-042088	Gasterosteus aculeatus	69.95	0.00e+00	1544.00
IUUC-Gma-043839	Glycine max	39.22	1.00e-108	386.00
IUUC-Ggo-045279	Gorilla gorilla	69.83	0.00e+00	1504.00
IUUC-Hsa-045660	Homo sapiens	69.74	0.00e+00	1504.00
IUUC-Hvu-047770	Hordeum vulgare	36.51	1.00e-110	392.00
IUUC-Itr-048372	Ictidomys tridecemlineatus	77.54	0.00e+00	696.00
IUUC-Lch-050664	Latimeria chalumnae	70.38	0.00e+00	1554.00
IUUC-Lpe-050755	Leersia perrieri	35.93	4.00e-95	341.00
IUUC-Loc-052791	Lepisosteus oculatus	71.34	0.00e+00	1518.00
IUUC-Laf-053902	Loxodonta africana	69.83	0.00e+00	1517.00
IUUC-Mcc-054730	Macaca mulatta	69.74	0.00e+00	1504.00
IUUC-Meu-056527	Macropus eugenii	65.05	0.00e+00	845.00
IUUC-Mtr-057671	Medicago truncatula	39.26	3.00e-109	388.00
IUUC-Mga-059260	Meleagris gallopavo	70.08	0.00e+00	1507.00
IUUC-Mmr-060804	Microcebus murinus	69.55	0.00e+00	1473.00
IUUC-Mdo-062575	Monodelphis domestica	69.75	0.00e+00	1484.00
IUUC-Mmu-063636	Mus musculus	69.46	0.00e+00	1473.00
IUUC-Mac-064989	Musa acuminata	39.65	9.00e-112	396.00
IUUC-Mpu-066677	Mustela putorius furo	69.14	0.00e+00	1401.00
IUUC-Mlu-067952	Myotis lucifugus	70.76	0.00e+00	1482.00
IUUC-Nle-069153	Nomascus leucogenys	69.74	0.00e+00	1503.00
IUUC-Opr-070554	Ochotona princeps	70.79	0.00e+00	1416.00
IUUC-Ont-071372	Oreochromis niloticus	70.55	0.00e+00	1538.00
IUUC-Oan-073327	Ornithorhynchus anatinus	59.66	2.00e-179	620.00
IUUC-Ocu-074183	Oryctolagus cuniculus	69.55	0.00e+00	1504.00
IUUC-Oba-075006	Oryza barthii	35.97	7.00e-114	404.00
IUUC-Obr-076320	Oryza brachyantha	39.03	3.00e-108	385.00
IUUC-Ogl-077093	Oryza glaberrima	38.75	3.00e-108	385.00
IUUC-Ogu-078947	Oryza glumaepatula	35.82	1.00e-113	402.00
IUUC-Oin-080058	Oryza indica	38.93	8.00e-109	387.00
IUUC-Olo-080475	Oryza longistaminata	36.12	2.00e-114	405.00
IUUC-Ome-081741	Oryza meridionalis	37.90	1.00e-101	363.00
IUUC-Oni-082385	Oryza nivara	35.82	1.00e-113	403.00
IUUC-Opu-083529	Oryza punctata	38.75	5.00e-108	384.00
IUUC-Oru-085128	Oryza rufipogon	37.43	8.00e-97	347.00
IUUC-Osa-085355	Oryza sativa	35.88	2.00e-114	405.00
IUUC-Ola-087337	Oryzias latipes	70.12	0.00e+00	1498.00
IUUC-Oga-088342	Otolemur garnettii	69.40	0.00e+00	1455.00
IUUC-Oar-090234	Ovis aries	70.18	0.00e+00	1526.00
IUUC-Ptr-091661	Pan troglodytes	69.83	0.00e+00	1504.00
IUUC-Pan-092728	Papio anubis	69.49	0.00e+00	1498.00
IUUC-Psi-093251	Pelodiscus sinensis	68.76	0.00e+00	1372.00
IUUC-Ppa-095544	Physcomitrella patens	37.79	1.00e-111	397.00
IUUC-Pfo-097472	Poecilia formosa	70.64	0.00e+00	1539.00
IUUC-Pab-098570	Pongo abelii	69.93	0.00e+00	1505.00
IUUC-Pca-100110	Procavia capensis	61.64	0.00e+00	1266.00
IUUC-Ppe-101281	Prunus persica	40.53	2.00e-109	389.00
IUUC-Pva-102887	Pteropus vampyrus	67.26	0.00e+00	1414.00
IUUC-Rno-106028	Rattus norvegicus	67.53	0.00e+00	1399.00
IUUC-Sha-107331	Sarcophilus harrisii	70.38	0.00e+00	1493.00
IUUC-Smo-109488	Selaginella moellendorffii	37.68	6.00e-108	384.00
IUUC-Sit-109811	Setaria italica	38.52	7.00e-107	380.00
IUUC-Sar-113287	Sorex araneus	56.76	2.00e-123	435.00
IUUC-Sbi-114433	Sorghum bicolor	38.00	8.00e-108	383.00
IUUC-Ssc-116103	Sus scrofa	70.39	0.00e+00	1502.00
IUUC-Tgu-117275	Taeniopygia guttata	70.31	0.00e+00	1506.00
IUUC-Tru-118681	Takifugu rubripes	70.18	0.00e+00	1558.00
IUUC-Tsy-118985	Tarsius syrichta	62.52	0.00e+00	682.00
IUUC-Tni-120850	Tetraodon nigroviridis	81.20	0.00e+00	696.00
IUUC-Tca-121770	Theobroma cacao	39.05	1.00e-111	396.00
IUUC-Tae-125466	Triticum aestivum	36.35	2.00e-110	392.00
IUUC-Tur-126086	Triticum urartu	38.08	2.00e-104	372.00
IUUC-Tbe-127461	Tupaia belangeri	66.39	0.00e+00	1362.00
IUUC-Ttr-129269	Tursiops truncatus	69.55	0.00e+00	1483.00
IUUC-Vpa-130523	Vicugna pacos	61.81	2.00e-94	338.00
IUUC-Vvi-131524	Vitis vinifera	39.49	6.00e-112	397.00
IUUC-Xtr-132146	Xenopus tropicalis	69.32	0.00e+00	1514.00
IUUC-Xma-133526	Xiphophorus maculatus	70.64	0.00e+00	1544.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence