iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gga-040147

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

E3 UFM1-protein ligase 1

Genbank Nucleotide ID

AADN04000258

Gene Name

UFL1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000015580.5	ENSGALT00000025123.5	ENSGALP00000025077.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	74.59	0.00e+00	1098.00	IUUC-Hsa-046823
ULD/UDP/UBQ/UBQ_Other	74.59	0.00e+00	1098.00	IUUC-Hsa-046823
E3 activity/Other	74.43	0.00e+00	1104.00	IUUC-Mmu-064248

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Gallus gallus

Protein Sequence
(Fasta)

MAADWEEIRR LAADFQRAQF AEAAHRLSER NCIEIVTKLI AEKQLEVVHT LDGKEYVTPA 60
QISKEIWDEL SVCGGRINIV DLQQIINVDL LHIENRANDI VKSDKAVQLV LGQLINESYL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTAGCCTCCC GGCGGGGCTG ACGTGGAGCG GGAGGGCGGC CATGGCGGCC GACTGGGAGG 60
AGATCCGGCG CTTGGCGGCC GATTTCCAGC GGGCTCAGTT TGCCGAGGCG GCCCACAGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR018611--E3_UFM1_ligase_1

Pfam

PF09743--DUF2042

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0043005--C:neuron projection
GO:0043234--C:protein complex
GO:0071568--F:UFM1 transferase activity
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0031397--P:negative regulation of protein ubiquitination
GO:0001649--P:osteoblast differentiation
GO:0060252--P:positive regulation of glial cell proliferation
GO:1990592--P:protein K69-linked ufmylation
GO:0033146--P:regulation of intracellular estrogen receptor signaling pathway
GO:0032434--P:regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032880--P:regulation of protein localization
GO:0034976--P:response to endoplasmic reticulum stress
GO:1902065--P:response to L-glutamate

KEGG

gga:421804

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000068	Aegilops tauschii	32.97	1.00e-44	174.00
IUUC-Aml-001894	Ailuropoda melanoleuca	74.84	0.00e+00	1143.00
IUUC-Atr-003137	Amborella trichopoda	33.16	3.00e-56	212.00
IUUC-Apl-003993	Anas platyrhynchos	91.05	0.00e+00	1346.00
IUUC-Aca-004941	Anolis carolinensis	76.97	0.00e+00	907.00
IUUC-Aly-006023	Arabidopsis lyrata	30.05	5.00e-51	196.00
IUUC-Ath-007249	Arabidopsis thaliana	30.31	2.00e-51	197.00
IUUC-Ame-011084	Astyanax mexicanus	72.76	5.00e-137	480.00
IUUC-Bta-012960	Bos taurus	75.35	0.00e+00	1134.00
IUUC-Bdi-014730	Brachypodium distachyon	34.23	3.00e-53	203.00
IUUC-Bol-016306	Brassica oleracea	26.80	1.00e-65	244.00
IUUC-Bra-016735	Brassica rapa	31.17	9.00e-50	191.00
IUUC-Cel-018267	Caenorhabditis elegans	29.82	3.00e-36	147.00
IUUC-Cja-019432	Callithrix jacchus	74.56	0.00e+00	1128.00
IUUC-Cfa-020879	Canis familiaris	74.06	0.00e+00	1103.00
IUUC-Cpo-021915	Cavia porcellus	71.11	0.00e+00	1046.00
IUUC-Cre-022838	Chlamydomonas reinhardtii	41.67	5.00e-23	100.00
IUUC-Csa-023667	Chlorocebus sabaeus	74.43	0.00e+00	1134.00
IUUC-Cin-025254	Ciona intestinalis	43.41	0.00e+00	628.00
IUUC-Csv-026110	Ciona savignyi	42.14	9.00e-178	617.00
IUUC-Dre-028832	Danio rerio	64.71	0.00e+00	932.00
IUUC-Dno-029396	Dasypus novemcinctus	70.36	0.00e+00	1007.00
IUUC-Dor-030872	Dipodomys ordii	62.33	1.00e-123	436.00
IUUC-Dme-031860	Drosophila melanogaster	44.62	3.00e-95	342.00
IUUC-Ete-032382	Echinops telfairi	71.32	0.00e+00	1064.00
IUUC-Eca-034175	Equus caballus	69.72	0.00e+00	1096.00
IUUC-Eeu-035073	Erinaceus europaeus	63.05	8.00e-139	487.00
IUUC-Fca-035655	Felis catus	71.38	0.00e+00	1078.00
IUUC-Fal-037594	Ficedula albicollis	87.74	0.00e+00	1134.00
IUUC-Gmo-038897	Gadus morhua	62.26	0.00e+00	843.00
IUUC-Gac-042365	Gasterosteus aculeatus	64.44	0.00e+00	1006.00
IUUC-Gma-044359	Glycine max	34.03	5.00e-44	172.00
IUUC-Ggo-045085	Gorilla gorilla	74.72	0.00e+00	1116.00
IUUC-Hsa-046823	Homo sapiens	74.97	0.00e+00	1119.00
IUUC-Hvu-047672	Hordeum vulgare	33.69	6.00e-53	202.00
IUUC-Itr-048558	Ictidomys tridecemlineatus	74.43	0.00e+00	1115.00
IUUC-Lch-050099	Latimeria chalumnae	73.39	0.00e+00	1137.00
IUUC-Lpe-051353	Leersia perrieri	33.15	3.00e-54	206.00
IUUC-Loc-052237	Lepisosteus oculatus	71.57	0.00e+00	1075.00
IUUC-Laf-053535	Loxodonta africana	70.26	0.00e+00	1038.00
IUUC-Mcc-054991	Macaca mulatta	74.31	0.00e+00	1134.00
IUUC-Meu-055924	Macropus eugenii	74.67	5.00e-91	328.00
IUUC-Mtr-058527	Medicago truncatula	33.16	3.00e-42	166.00
IUUC-Mga-059514	Meleagris gallopavo	98.10	0.00e+00	1449.00
IUUC-Mmr-061625	Microcebus murinus	74.56	0.00e+00	1129.00
IUUC-Mdo-062551	Monodelphis domestica	76.98	0.00e+00	1165.00
IUUC-Mmu-064248	Mus musculus	74.43	0.00e+00	1094.00
IUUC-Mac-065571	Musa acuminata	34.09	2.00e-59	223.00
IUUC-Mpu-065883	Mustela putorius furo	73.84	0.00e+00	1125.00
IUUC-Mlu-067468	Myotis lucifugus	73.84	0.00e+00	1118.00
IUUC-Nle-069831	Nomascus leucogenys	74.72	0.00e+00	1135.00
IUUC-Opr-071153	Ochotona princeps	58.19	0.00e+00	683.00
IUUC-Ont-072677	Oreochromis niloticus	68.01	0.00e+00	1010.00
IUUC-Oan-073682	Ornithorhynchus anatinus	75.36	0.00e+00	1047.00
IUUC-Ocu-074268	Oryctolagus cuniculus	74.94	0.00e+00	1144.00
IUUC-Oba-075467	Oryza barthii	32.22	4.00e-51	196.00
IUUC-Obr-076760	Oryza brachyantha	33.43	1.00e-53	204.00
IUUC-Ogl-077088	Oryza glaberrima	32.21	2.00e-51	197.00
IUUC-Ogu-078509	Oryza glumaepatula	32.81	2.00e-53	204.00
IUUC-Oin-079276	Oryza indica	32.98	9.00e-54	205.00
IUUC-Olo-080814	Oryza longistaminata	32.22	3.00e-51	196.00
IUUC-Ome-081647	Oryza meridionalis	32.98	9.00e-54	205.00
IUUC-Oni-082954	Oryza nivara	32.22	3.00e-51	196.00
IUUC-Opu-083580	Oryza punctata	32.78	8.00e-46	178.00
IUUC-Oru-084627	Oryza rufipogon	32.98	9.00e-54	205.00
IUUC-Osa-086096	Oryza sativa	32.98	9.00e-54	205.00
IUUC-Ola-087322	Oryzias latipes	65.19	0.00e+00	1016.00
IUUC-Olu-087693	Ostreococcus lucimarinus	25.45	6.00e-18	85.50
IUUC-Oga-088769	Otolemur garnettii	71.36	0.00e+00	1062.00
IUUC-Oar-090007	Ovis aries	74.37	0.00e+00	1125.00
IUUC-Ptr-090760	Pan troglodytes	74.97	0.00e+00	1117.00
IUUC-Pan-092162	Papio anubis	74.56	0.00e+00	1136.00
IUUC-Psi-093045	Pelodiscus sinensis	83.36	0.00e+00	1197.00
IUUC-Ppa-095424	Physcomitrella patens	34.67	1.00e-58	221.00
IUUC-Pfo-096108	Poecilia formosa	66.08	0.00e+00	1012.00
IUUC-Pab-098057	Pongo abelii	72.70	0.00e+00	1092.00
IUUC-Pop-099790	Populus trichocarpa	32.82	2.00e-57	217.00
IUUC-Pca-100307	Procavia capensis	69.81	0.00e+00	1044.00
IUUC-Ppe-102029	Prunus persica	30.79	2.00e-54	207.00
IUUC-Pva-102386	Pteropus vampyrus	72.59	0.00e+00	684.00
IUUC-Rno-105550	Rattus norvegicus	74.69	0.00e+00	1071.00
IUUC-Sha-107442	Sarcophilus harrisii	77.61	0.00e+00	1164.00
IUUC-Smo-109447	Selaginella moellendorffii	33.42	3.00e-57	216.00
IUUC-Sit-110568	Setaria italica	33.61	2.00e-52	200.00
IUUC-Sly-111028	Solanum lycopersicum	32.30	3.00e-52	199.00
IUUC-Stu-112317	Solanum tuberosum	31.78	2.00e-50	194.00
IUUC-Sar-113662	Sorex araneus	68.88	0.00e+00	1026.00
IUUC-Sbi-114636	Sorghum bicolor	33.42	3.00e-53	203.00
IUUC-Ssc-116423	Sus scrofa	74.72	0.00e+00	1132.00
IUUC-Tgu-116977	Taeniopygia guttata	85.98	0.00e+00	1311.00
IUUC-Tru-118314	Takifugu rubripes	63.14	0.00e+00	961.00
IUUC-Tsy-119391	Tarsius syrichta	72.33	0.00e+00	1071.00
IUUC-Tni-120594	Tetraodon nigroviridis	65.69	0.00e+00	952.00
IUUC-Tca-121351	Theobroma cacao	31.34	9.00e-56	211.00
IUUC-Tae-122849	Triticum aestivum	29.69	4.00e-22	99.80
IUUC-Tur-126308	Triticum urartu	30.13	1.00e-22	101.00
IUUC-Tbe-127999	Tupaia belangeri	72.98	0.00e+00	1011.00
IUUC-Ttr-129189	Tursiops truncatus	69.65	0.00e+00	1035.00
IUUC-Vpa-130734	Vicugna pacos	71.03	0.00e+00	1041.00
IUUC-Vvi-131695	Vitis vinifera	32.31	2.00e-52	201.00
IUUC-Xtr-132004	Xenopus tropicalis	67.67	0.00e+00	1013.00
IUUC-Xma-134108	Xiphophorus maculatus	65.51	0.00e+00	901.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence