iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000018996.5	ENSBTAT00000062978.1	ENSBTAP00000055410.1
ENSBTAG00000018996.5	ENSBTAT00000065043.1	ENSBTAP00000054449.1
ENSBTAG00000018996.5	ENSBTAT00000064741.1	ENSBTAP00000055427.1
ENSBTAG00000018996.5	ENSBTAT00000064168.1	ENSBTAP00000055262.1
ENSBTAG00000018996.5	ENSBTAT00000025286.5	ENSBTAP00000025286.5
ENSBTAG00000018996.5	ENSBTAT00000063967.1	ENSBTAP00000056268.1
ENSBTAG00000018996.5	ENSBTAT00000064521.1	ENSBTAP00000054593.1

Status

Reviewed

Details

Family	Domain	References (PMIDs)
ULD/UDP/UBQ/UBQ_PIM	UBQ_PIM	20064468

Classification

Family	E-value	Score	Start	End
ULD/UDP/UBQ/UBQ_PIM	8.30e-24	83.5	1	75

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UBQ/UBQ_PIM

   S: 1    mkltvktlkgkefelevseddtveelKekiakesgvppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvkksk 75
           mk++v++++ + f++ev++d+++ +lKe +a+++gvp++q+ +I+aGk+L++d+t+++++++++s+vh+v+++++
   Q: 1    MKVFVRFNSNHGFPVEVDSDTSIFQLKEVVARRQGVPADQLCVIFAGKELRNDWTVQSCDLDQQSIVHIVLRPRR 75
           99*****99999**********************************************************99875 PP

Organism

Bos taurus

Functional Description
(View)

Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.

Protein Sequence
(Fasta)

MKVFVRFNSN HGFPVEVDSD TSIFQLKEVV ARRQGVPADQ LCVIFAGKEL RNDWTVQSCD 60
LDQQSIVHIV LRPRRKGPEG HSPRPAWGRS DREPESLTRV DLSSSMLPAD SVGLAVILQD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTTTGCCTG AACAACTGGT CTCGGAGGGA GCTTGGACTC GCTGACAACG ATGAAAGGTA 60
AATCAGCCCT GCTTTGTTGT TGTTATTGCT CAGTCTCCAG TGGTGTCCGA CTCTGTGACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR003977--Parkin
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50053--UBIQUITIN_2

Pfam

PF01485--IBR
PF00240--ubiquitin

PRINTS

PR01475--PARKIN

SMART

SM00647--IBR
SM00213--UBQ

Gene Ontology

GO:0005829--C:cytosol
GO:0005739--C:mitochondrion
GO:0005634--C:nucleus
GO:0000151--C:ubiquitin ligase complex
GO:0046872--F:metal ion binding
GO:0004842--F:ubiquitin-protein transferase activity

KEGG

bta:530858

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001814	Ailuropoda melanoleuca	84.03	3.00e-139	487.00
IUUC-Apl-003304	Anas platyrhynchos	78.50	2.00e-141	494.00
IUUC-Aca-004908	Anolis carolinensis	72.60	2.00e-27	114.00
IUUC-Ame-011856	Astyanax mexicanus	63.53	3.00e-157	548.00
IUUC-Cel-018687	Caenorhabditis elegans	29.76	1.00e-33	137.00
IUUC-Cja-019274	Callithrix jacchus	82.29	2.00e-138	484.00
IUUC-Cfa-020461	Canis familiaris	82.99	3.00e-138	484.00
IUUC-Cpo-022251	Cavia porcellus	80.56	7.00e-136	476.00
IUUC-Csa-023112	Chlorocebus sabaeus	81.25	5.00e-129	453.00
IUUC-Cho-024504	Choloepus hoffmanni	57.98	8.00e-121	427.00
IUUC-Dre-028202	Danio rerio	61.74	4.00e-140	491.00
IUUC-Dno-028946	Dasypus novemcinctus	65.22	2.00e-19	87.00
IUUC-Dor-030508	Dipodomys ordii	70.19	2.00e-134	472.00
IUUC-Dme-031980	Drosophila melanogaster	41.84	2.00e-90	325.00
IUUC-Ete-032281	Echinops telfairi	67.60	4.00e-89	321.00
IUUC-Eca-033228	Equus caballus	83.74	1.00e-140	491.00
IUUC-Fca-036045	Felis catus	67.07	3.00e-21	92.40
IUUC-Fal-037507	Ficedula albicollis	71.83	0.00e+00	636.00
IUUC-Gmo-038744	Gadus morhua	56.97	3.00e-79	288.00
IUUC-Gga-040353	Gallus gallus	71.33	9.00e-178	616.00
IUUC-Gac-042519	Gasterosteus aculeatus	48.86	3.00e-116	411.00
IUUC-Hsa-046016	Homo sapiens	84.38	0.00e+00	715.00
IUUC-Itr-048744	Ictidomys tridecemlineatus	81.46	0.00e+00	673.00
IUUC-Loc-052389	Lepisosteus oculatus	65.67	6.00e-155	540.00
IUUC-Laf-053412	Loxodonta africana	58.89	4.00e-20	89.00
IUUC-Mcc-054933	Macaca mulatta	83.68	0.00e+00	709.00
IUUC-Meu-055963	Macropus eugenii	60.48	9.00e-111	393.00
IUUC-Mga-059626	Meleagris gallopavo	80.00	1.00e-32	130.00
IUUC-Mmr-061566	Microcebus murinus	85.33	6.00e-73	266.00
IUUC-Mdo-062933	Monodelphis domestica	83.33	4.00e-32	128.00
IUUC-Mmu-063561	Mus musculus	79.49	0.00e+00	698.00
IUUC-Mpu-065799	Mustela putorius furo	80.56	8.00e-133	466.00
IUUC-Mlu-068134	Myotis lucifugus	79.94	5.00e-157	546.00
IUUC-Nle-070078	Nomascus leucogenys	80.94	6.00e-141	493.00
IUUC-Opr-070541	Ochotona princeps	81.22	0.00e+00	655.00
IUUC-Ont-071743	Oreochromis niloticus	53.55	3.00e-116	411.00
IUUC-Oan-073700	Ornithorhynchus anatinus	85.19	1.00e-22	97.10
IUUC-Ola-086426	Oryzias latipes	59.29	1.00e-45	175.00
IUUC-Oga-088867	Otolemur garnettii	84.31	0.00e+00	697.00
IUUC-Oar-089365	Ovis aries	92.48	0.00e+00	681.00
IUUC-Ptr-091371	Pan troglodytes	84.15	0.00e+00	712.00
IUUC-Pan-092443	Papio anubis	81.60	1.00e-136	479.00
IUUC-Psi-093851	Pelodiscus sinensis	67.93	1.00e-94	338.00
IUUC-Pfo-097194	Poecilia formosa	49.20	9.00e-114	403.00
IUUC-Pab-097999	Pongo abelii	69.52	2.00e-131	461.00
IUUC-Pca-100410	Procavia capensis	77.65	0.00e+00	657.00
IUUC-Pva-102300	Pteropus vampyrus	73.18	4.00e-167	580.00
IUUC-Rno-105556	Rattus norvegicus	78.47	2.00e-131	461.00
IUUC-Sha-106992	Sarcophilus harrisii	90.74	2.00e-25	106.00
IUUC-Sar-113121	Sorex araneus	88.79	3.00e-59	222.00
IUUC-Ssc-116435	Sus scrofa	83.28	4.00e-139	487.00
IUUC-Tgu-117489	Taeniopygia guttata	71.00	0.00e+00	634.00
IUUC-Tru-117927	Takifugu rubripes	50.11	3.00e-123	435.00
IUUC-Tsy-119372	Tarsius syrichta	88.32	1.00e-148	519.00
IUUC-Tni-120043	Tetraodon nigroviridis	48.88	4.00e-112	398.00
IUUC-Tbe-127539	Tupaia belangeri	74.88	2.00e-173	601.00
IUUC-Ttr-129149	Tursiops truncatus	82.52	0.00e+00	722.00
IUUC-Vpa-130439	Vicugna pacos	66.84	2.00e-139	488.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence