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Tag Content
iUUCD ID IUUC-Sha-107066
Ensembl Protein ID ENSSHAP00000014725.1
UniProt Accession G3WH20; G3WH20_SARHA
Genbank Protein ID ENSSHAP00000014725
Protein Name Uncharacterized protein
Genbank Nucleotide ID AEFK01164312
Gene Name HGS
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSSHAG00000012570.1 ENSSHAT00000014848.1 ENSSHAP00000014724.1
ENSSHAG00000012570.1 ENSSHAT00000014849.1 ENSSHAP00000014725.1
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/Alpha-Helix/VHS 4.90e-51 172.4 15 143
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/Alpha-Helix/VHS
   S: 1    atselvtsedwelileicdliqetkegakdalralrkrinnknphvalraLtlLdscvsnCgkkfhvevaskdlleelrellknenepk 89
           ats+l+ ++dwe+il+icd+i++ +++ak+a+ +++k++n+knphval+aL++++s+v+nCg+++h+eva+k+++eel+ellk+++e++
   Q: 15   ATSQLLLETDWESILQICDMIRQGDTQAKYAVSSIKKKVNDKNPHVALYALEVMESVVKNCGQTVHDEVANKQTMEELKELLKRQVEVN 103
           799************************************************************************************** PP
   S: 90   vieKlkalivsWadelknepalslivaliktlkeeGlefp 129
           v++K+++li++Wa++++nep++++++++++ +k eG++fp
   Q: 104  VRNKILYLIQAWAHAFRNEPKYKVVQDTYQIMKVEGHVFP 143
           ***************************************8 PP
   
Organism Sarcophilus harrisii
Protein Sequence
(Fasta)
MGRGSGTFER LLDKATSQLL LETDWESILQ ICDMIRQGDT QAKYAVSSIK KKVNDKNPHV 60
ALYALEVMES VVKNCGQTVH DEVANKQTME ELKELLKRQV EVNVRNKILY LIQAWAHAFR 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Sha-107066|UBD,VHS|Sarcophilus harrisii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGGGAGAG GTAGCGGCAC CTTCGAGCGT CTCCTAGGTA ACGTGGCCCC AGACGGACAG 60
CTTCCCCCAC CCCCCCCCTC CCCTCCAGCG CCGATCTGGG GCTGGCCGGN NNNNNNNNNN 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Sha-107066|UBD,VHS|Sarcophilus harrisii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR008942--ENTH_VHS
IPR024641--HRS_helical
IPR017073--Ubi-bd_Hrs_VPS27
IPR003903--UIM_dom
IPR002014--VHS_dom
IPR000306--Znf_FYVE
IPR017455--Znf_FYVE-rel
IPR011011--Znf_FYVE_PHD
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS50330--UIM
PS50179--VHS
PS50178--ZF_FYVE
Pfam

PF01363--FYVE
PF12210--Hrs_helical
PF00790--VHS
SMART

SM00064--FYVE
SM00288--VHS
Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0070062--C:extracellular exosome
GO:0005764--C:lysosome
GO:0046872--F:metal ion binding
GO:0010324--P:membrane invagination
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:1903543--P:positive regulation of exosomal secretion
GO:0010628--P:positive regulation of gene expression
GO:0072657--P:protein localization to membrane
GO:0006622--P:protein targeting to lysosome
GO:0043405--P:regulation of MAP kinase activity
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001518 Ailuropoda melanoleuca 86.48 0.00e+00 965.00
IUUC-Apl-003662 Anas platyrhynchos 84.87 0.00e+00 1015.00
IUUC-Aca-004940 Anolis carolinensis 86.19 0.00e+00 1159.00
IUUC-Ago-007931 Ashbya gossypii 30.58 9.00e-27 115.00
IUUC-Acl-008274 Aspergillus clavatus 31.05 3.00e-39 156.00
IUUC-Afl-008521 Aspergillus flavus 32.85 3.00e-40 159.00
IUUC-Afu-008774 Aspergillus fumigatus 32.59 3.00e-40 159.00
IUUC-Ani-009445 Aspergillus nidulans 32.59 1.00e-40 161.00
IUUC-Ang-009863 Aspergillus niger 33.21 5.00e-42 165.00
IUUC-Ate-010444 Aspergillus terreus 35.16 2.00e-42 166.00
IUUC-Ame-011111 Astyanax mexicanus 80.61 0.00e+00 954.00
IUUC-Bgr-012087 Blumeria graminis 33.57 2.00e-42 167.00
IUUC-Bta-012506 Bos taurus 90.32 0.00e+00 1122.00
IUUC-Bci-013782 Botrytis cinerea 31.08 2.00e-41 164.00
IUUC-Cel-018493 Caenorhabditis elegans 53.33 4.00e-68 252.00
IUUC-Cja-019998 Callithrix jacchus 86.41 0.00e+00 1025.00
IUUC-Cfa-020615 Canis familiaris 90.52 0.00e+00 1047.00
IUUC-Cpo-022019 Cavia porcellus 88.92 0.00e+00 1158.00
IUUC-Csa-023596 Chlorocebus sabaeus 89.90 0.00e+00 1019.00
IUUC-Cin-025488 Ciona intestinalis 46.32 4.00e-128 452.00
IUUC-Csv-025802 Ciona savignyi 50.09 2.00e-115 409.00
IUUC-Cgl-026560 Colletotrichum gloeosporioides 33.33 5.00e-40 159.00
IUUC-Cne-026847 Cryptococcus neoformans 31.89 1.00e-37 151.00
IUUC-Dre-028353 Danio rerio 80.62 0.00e+00 945.00
IUUC-Dno-029005 Dasypus novemcinctus 87.80 0.00e+00 1099.00
IUUC-Dor-030280 Dipodomys ordii 86.65 0.00e+00 1098.00
IUUC-Dse-031238 Dothistroma septosporum 38.71 2.00e-42 167.00
IUUC-Dme-031952 Drosophila melanogaster 47.35 6.00e-79 288.00
IUUC-Ete-032235 Echinops telfairi 96.36 3.00e-131 462.00
IUUC-Eca-033873 Equus caballus 91.03 0.00e+00 1112.00
IUUC-Eeu-034652 Erinaceus europaeus 96.09 6.00e-105 375.00
IUUC-Fca-036563 Felis catus 89.64 0.00e+00 1090.00
IUUC-Fal-036649 Ficedula albicollis 87.50 0.00e+00 1028.00
IUUC-Fox-037962 Fusarium oxysporum 33.09 9.00e-39 155.00
IUUC-Fso-038396 Fusarium solani 33.33 3.00e-39 157.00
IUUC-Gmo-039510 Gadus morhua 80.60 0.00e+00 924.00
IUUC-Ggr-039938 Gaeumannomyces graminis 32.33 4.00e-37 149.00
IUUC-Gga-040201 Gallus gallus 87.38 0.00e+00 1111.00
IUUC-Gac-041459 Gasterosteus aculeatus 78.82 0.00e+00 960.00
IUUC-Ggo-044573 Gorilla gorilla 90.04 0.00e+00 1116.00
IUUC-Hsa-046009 Homo sapiens 90.18 0.00e+00 1162.00
IUUC-Hvu-047560 Hordeum vulgare 39.10 2.00e-23 103.00
IUUC-Itr-049065 Ictidomys tridecemlineatus 88.95 0.00e+00 1171.00
IUUC-Kpa-049327 Komagataella pastoris 31.11 4.00e-32 132.00
IUUC-Lch-049944 Latimeria chalumnae 82.49 3.00e-165 574.00
IUUC-Lpe-051031 Leersia perrieri 36.57 3.00e-23 103.00
IUUC-Loc-051850 Lepisosteus oculatus 82.94 0.00e+00 1035.00
IUUC-Lma-053252 Leptosphaeria maculans 35.65 5.00e-41 162.00
IUUC-Laf-053346 Loxodonta africana 90.91 0.00e+00 1011.00
IUUC-Mcc-055789 Macaca mulatta 90.04 0.00e+00 1090.00
IUUC-Meu-056329 Macropus eugenii 84.00 1.00e-172 599.00
IUUC-Mor-057205 Magnaporthe oryzae 33.56 5.00e-38 152.00
IUUC-Mpo-057295 Magnaporthe poae 32.69 9.00e-39 155.00
IUUC-Mla-058849 Melampsora laricipopulina 32.58 1.00e-31 131.00
IUUC-Mga-059361 Meleagris gallopavo 86.89 0.00e+00 1039.00
IUUC-Mvi-060561 Microbotryum violaceum 32.91 3.00e-40 159.00
IUUC-Mmr-061122 Microcebus murinus 91.23 0.00e+00 1004.00
IUUC-Mdo-062171 Monodelphis domestica 98.32 0.00e+00 1248.00
IUUC-Mmu-063952 Mus musculus 89.90 0.00e+00 1188.00
IUUC-Mac-064432 Musa acuminata 36.62 8.00e-24 105.00
IUUC-Mpu-065852 Mustela putorius furo 88.49 0.00e+00 1059.00
IUUC-Mlu-066996 Myotis lucifugus 80.39 2.00e-132 465.00
IUUC-Nfi-068539 Neosartorya fischeri 32.59 2.00e-40 160.00
IUUC-Ncr-068726 Neurospora crassa 39.19 2.00e-39 157.00
IUUC-Nle-070148 Nomascus leucogenys 85.13 0.00e+00 1007.00
IUUC-Opr-070833 Ochotona princeps 69.04 0.00e+00 734.00
IUUC-Ont-071261 Oreochromis niloticus 79.37 0.00e+00 976.00
IUUC-Oan-073684 Ornithorhynchus anatinus 72.85 1.00e-164 572.00
IUUC-Ome-081173 Oryza meridionalis 36.84 2.00e-23 103.00
IUUC-Opu-083866 Oryza punctata 36.84 1.00e-23 104.00
IUUC-Ola-087570 Oryzias latipes 76.61 0.00e+00 944.00
IUUC-Oga-089087 Otolemur garnettii 85.57 0.00e+00 1039.00
IUUC-Oar-089534 Ovis aries 90.46 0.00e+00 1123.00
IUUC-Ptr-091654 Pan troglodytes 84.15 0.00e+00 1009.00
IUUC-Pan-092652 Papio anubis 90.04 0.00e+00 1090.00
IUUC-Pno-095125 Phaeosphaeria nodorum 37.39 5.00e-42 165.00
IUUC-Pfo-096757 Poecilia formosa 78.98 0.00e+00 934.00
IUUC-Pab-097788 Pongo abelii 91.91 0.00e+00 824.00
IUUC-Pca-100145 Procavia capensis 77.14 0.00e+00 838.00
IUUC-Pva-102965 Pteropus vampyrus 86.54 0.00e+00 1053.00
IUUC-Pgr-103609 Puccinia graminis 30.86 5.00e-33 135.00
IUUC-Ptt-103865 Puccinia triticina 35.44 5.00e-34 139.00
IUUC-Pte-104095 Pyrenophora teres 35.24 2.00e-41 164.00
IUUC-Pyt-104668 Pyrenophora triticirepentis 35.87 4.00e-41 162.00
IUUC-Rno-105125 Rattus norvegicus 89.48 0.00e+00 1111.00
IUUC-Sce-106192 Saccharomyces cerevisiae 29.28 5.00e-27 115.00
IUUC-Sja-107931 Schizosaccharomyces japonicus 34.37 2.00e-41 164.00
IUUC-Spo-108220 Schizosaccharomyces pombe 33.94 1.00e-38 154.00
IUUC-Smo-109345 Selaginella moellendorffii 37.76 6.00e-21 94.70
IUUC-Stu-112464 Solanum tuberosum 45.31 4.00e-13 70.90
IUUC-Sar-113393 Sorex araneus 91.05 4.00e-105 375.00
IUUC-Sre-114986 Sporisorium reilianum 39.01 2.00e-42 167.00
IUUC-Tgu-117505 Taeniopygia guttata 85.63 0.00e+00 1021.00
IUUC-Tru-118494 Takifugu rubripes 79.03 0.00e+00 1004.00
IUUC-Tsy-119626 Tarsius syrichta 96.91 1.00e-52 201.00
IUUC-Tni-120174 Tetraodon nigroviridis 78.30 0.00e+00 967.00
IUUC-Tre-122191 Trichoderma reesei 33.45 1.00e-39 157.00
IUUC-Tvi-122318 Trichoderma virens 32.98 2.00e-40 160.00
IUUC-Tme-126914 Tuber melanosporum 34.75 4.00e-44 172.00
IUUC-Ttr-129095 Tursiops truncatus 91.02 0.00e+00 1162.00
IUUC-Uma-129475 Ustilago maydis 31.65 1.00e-39 158.00
IUUC-Vda-129908 Verticillium dahliae 32.75 7.00e-35 142.00
IUUC-Xtr-131900 Xenopus tropicalis 81.88 0.00e+00 1031.00
IUUC-Xma-133124 Xiphophorus maculatus 78.90 0.00e+00 984.00
IUUC-Yli-134682 Yarrowia lipolytica 32.73 8.00e-32 131.00
Created Date 25-Jun-2017

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