iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-045504

UUCD1 version

UUC-GoG-00415

Ensembl Protein ID

ENSGGOP00000025309.1

UniProt Accession

G3SB35; G3SB35_GORGO

Protein Name

Uncharacterized protein

Gene Name

HECTD2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000010273.2	ENSGGOT00000027198.1	ENSGGOP00000025309.1
ENSGGOG00000010273.2	ENSGGOT00000010323.2	ENSGGOP00000010033.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.30e-102	344.1	442	780

Active Site

Position(s)	Description	Evidence
748	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           ++dlkk+l+v+fvgE+gld+gG+t+e++ ll++++++pd+g+f+y+++++++++ + +      ++ + F+++G+l+g+a++++  ld+
   Q: 442  RADLKKKLKVTFVGEAGLDMGGLTKEWFLLLIRQIFHPDYGMFTYHKDSHCHWFSSFKC-----DNYSEFRLVGILMGLAVYNSITLDI 525
           589***************************************************87766.....789********************** PP
   S: 91   plsksfyklllgk..............klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipV 165
           ++++++yk+ll+               +++++dl +++pel++ l e++++ e ++ee  +  tf+v +e++g +k+++LkpgG++i+V
   Q: 526  RFPPCCYKKLLSPpiipsdqnipvgicNVTVDDLCQIMPELAHGLSELLSH-EGNVEED-FYSTFQVFQEEFGIIKSYNLKPGGDKISV 612
           *************777777766666666*********************98.6788885.***************************** PP
   S: 166  tneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevle 254
           tn+N++eYv+l++++ l+++i +q++af+ Gf++v+  + l l+++ee+e+l+cG++++d+++l++ t+y+g y +++ +i++Fw+v+ 
   Q: 613  TNQNRKEYVQLYTDFLLNKSIYKQFAAFYYGFHSVCASNALMLLRPEEVEILVCGSPDLDMHALQRSTQYDG-YAKTDLTIKYFWDVVL 700
           **********************************************************************76.**************** PP
   S: 255  efsseerkafLqFvTgssrlPlgGfaelkprlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           +f  + +k++L+F+Tgs+r+P+gG+a+l+   f i+k ++s++ lP ++TCfn+L+LP+Y+sk+ lk+kL++ i++++gF+l+
   Q: 701  GFPLDLQKKLLHFTTGSDRVPVGGMADLN---FKISKnETSTNCLPVAHTCFNQLCLPPYKSKKDLKQKLIIGISNSEGFGLE 780
           *****************************...9999966777**************************************985 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MSEAVRVPSP ATPLVVAAAA PEERKGKESE REKLPPIVSA GAGATAGLDR GAKGQISTFS 60
SFISAVSPKK EAAENRSSPA HLVFPNIKNV REQPPVCVDV RQKQRTSMDA SSSEMKAPVL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCGACATGA GTGAGGCGGT TCGGGTACCC TCGCCCGCCA CTCCGCTGGT GGTGGCGGCG 60
GCCGCGCCTG AGGAGAGGAA AGGGAAGGAG TCGGAGCGCG AGAAGCTGCC GCCCATCGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001266	Ailuropoda melanoleuca	95.37	0.00e+00	1473.00
IUUC-Apl-003589	Anas platyrhynchos	84.35	0.00e+00	1281.00
IUUC-Aca-004350	Anolis carolinensis	79.65	0.00e+00	1207.00
IUUC-Ago-007908	Ashbya gossypii	34.86	7.00e-83	301.00
IUUC-Acl-008288	Aspergillus clavatus	34.64	2.00e-96	347.00
IUUC-Afl-008402	Aspergillus flavus	33.83	3.00e-90	326.00
IUUC-Afu-008762	Aspergillus fumigatus	33.93	2.00e-93	337.00
IUUC-Ani-009176	Aspergillus nidulans	34.65	3.00e-92	333.00
IUUC-Ang-009791	Aspergillus niger	34.98	2.00e-92	333.00
IUUC-Aor-009921	Aspergillus oryzae	33.44	1.00e-89	324.00
IUUC-Ate-010295	Aspergillus terreus	35.09	1.00e-99	357.00
IUUC-Ame-010660	Astyanax mexicanus	81.61	8.00e-151	525.00
IUUC-Bgr-011981	Blumeria graminis	30.78	4.00e-94	340.00
IUUC-Bta-012945	Bos taurus	92.74	0.00e+00	1416.00
IUUC-Bci-013697	Botrytis cinerea	36.65	8.00e-81	295.00
IUUC-Cja-019263	Callithrix jacchus	97.58	0.00e+00	1486.00
IUUC-Cfa-020486	Canis familiaris	95.99	0.00e+00	1308.00
IUUC-Cpo-021755	Cavia porcellus	92.49	0.00e+00	1439.00
IUUC-Csa-023814	Chlorocebus sabaeus	98.01	0.00e+00	1408.00
IUUC-Cho-024980	Choloepus hoffmanni	77.05	0.00e+00	1151.00
IUUC-Cgl-026526	Colletotrichum gloeosporioides	42.05	3.00e-99	357.00
IUUC-Dre-028551	Danio rerio	74.30	0.00e+00	1146.00
IUUC-Dno-029497	Dasypus novemcinctus	91.79	0.00e+00	1281.00
IUUC-Dor-030867	Dipodomys ordii	81.04	0.00e+00	1183.00
IUUC-Dse-031239	Dothistroma septosporum	29.24	9.00e-89	322.00
IUUC-Ete-032902	Echinops telfairi	78.09	0.00e+00	1181.00
IUUC-Eca-033678	Equus caballus	94.28	0.00e+00	1426.00
IUUC-Eeu-035262	Erinaceus europaeus	76.67	0.00e+00	1051.00
IUUC-Fca-035590	Felis catus	94.41	0.00e+00	1455.00
IUUC-Fal-037123	Ficedula albicollis	79.97	0.00e+00	1234.00
IUUC-Fox-037941	Fusarium oxysporum	39.68	2.00e-101	364.00
IUUC-Fso-038388	Fusarium solani	40.28	5.00e-104	372.00
IUUC-Gmo-039553	Gadus morhua	66.05	0.00e+00	853.00
IUUC-Ggr-040110	Gaeumannomyces graminis	40.08	8.00e-100	358.00
IUUC-Gga-040406	Gallus gallus	83.73	0.00e+00	1319.00
IUUC-Gac-042141	Gasterosteus aculeatus	75.04	0.00e+00	1109.00
IUUC-Hsa-045786	Homo sapiens	98.97	0.00e+00	1509.00
IUUC-Itr-048050	Ictidomys tridecemlineatus	87.72	0.00e+00	1229.00
IUUC-Kpa-049152	Komagataella pastoris	33.98	3.00e-78	286.00
IUUC-Lch-049824	Latimeria chalumnae	79.83	0.00e+00	1102.00
IUUC-Loc-052173	Lepisosteus oculatus	77.20	0.00e+00	1201.00
IUUC-Laf-054017	Loxodonta africana	93.49	0.00e+00	1340.00
IUUC-Mcc-055713	Macaca mulatta	97.98	0.00e+00	1472.00
IUUC-Meu-056212	Macropus eugenii	68.83	3.00e-115	409.00
IUUC-Mor-057045	Magnaporthe oryzae	36.59	2.00e-92	334.00
IUUC-Mla-059187	Melampsora laricipopulina	43.83	2.00e-88	318.00
IUUC-Mga-059884	Meleagris gallopavo	77.72	0.00e+00	1166.00
IUUC-Mmr-061344	Microcebus murinus	92.33	0.00e+00	1413.00
IUUC-Mdo-062653	Monodelphis domestica	86.32	0.00e+00	1321.00
IUUC-Mmu-063775	Mus musculus	88.38	0.00e+00	1299.00
IUUC-Mpu-066069	Mustela putorius furo	95.80	0.00e+00	1338.00
IUUC-Mlu-067925	Myotis lucifugus	93.05	0.00e+00	1388.00
IUUC-Nfi-068439	Neosartorya fischeri	33.93	6.00e-94	339.00
IUUC-Ncr-068903	Neurospora crassa	37.07	3.00e-94	340.00
IUUC-Nle-070046	Nomascus leucogenys	98.13	0.00e+00	1515.00
IUUC-Opr-071085	Ochotona princeps	79.19	8.00e-138	484.00
IUUC-Ont-072126	Oreochromis niloticus	71.81	0.00e+00	1161.00
IUUC-Oan-072933	Ornithorhynchus anatinus	88.33	0.00e+00	1187.00
IUUC-Ocu-073800	Oryctolagus cuniculus	95.35	0.00e+00	1313.00
IUUC-Ola-086988	Oryzias latipes	75.25	0.00e+00	1114.00
IUUC-Oga-088117	Otolemur garnettii	95.34	0.00e+00	1146.00
IUUC-Oar-089371	Ovis aries	92.64	0.00e+00	1377.00
IUUC-Ptr-090551	Pan troglodytes	98.59	0.00e+00	1462.00
IUUC-Pan-092067	Papio anubis	97.85	0.00e+00	1463.00
IUUC-Psi-092963	Pelodiscus sinensis	84.47	0.00e+00	1272.00
IUUC-Pfo-096562	Poecilia formosa	69.61	0.00e+00	1123.00
IUUC-Pab-098680	Pongo abelii	98.46	0.00e+00	1506.00
IUUC-Pca-100986	Procavia capensis	74.67	0.00e+00	904.00
IUUC-Pva-102219	Pteropus vampyrus	78.69	0.00e+00	1088.00
IUUC-Pgr-103315	Puccinia graminis	35.95	2.00e-95	343.00
IUUC-Ptt-103736	Puccinia triticina	41.49	2.00e-95	343.00
IUUC-Rno-105270	Rattus norvegicus	88.19	0.00e+00	1305.00
IUUC-Sce-106306	Saccharomyces cerevisiae	34.25	5.00e-70	259.00
IUUC-Sha-106819	Sarcophilus harrisii	88.83	0.00e+00	1368.00
IUUC-Spo-108271	Schizosaccharomyces pombe	32.42	6.00e-88	318.00
IUUC-Ssl-108657	Sclerotinia sclerotiorum	30.50	3.00e-84	307.00
IUUC-Sar-113134	Sorex araneus	84.74	0.00e+00	1235.00
IUUC-Ssc-115441	Sus scrofa	93.56	0.00e+00	1395.00
IUUC-Tgu-117166	Taeniopygia guttata	82.86	0.00e+00	1253.00
IUUC-Tsy-118898	Tarsius syrichta	81.82	0.00e+00	1147.00
IUUC-Tre-122108	Trichoderma reesei	38.18	1.00e-90	328.00
IUUC-Tvi-122644	Trichoderma virens	38.31	2.00e-95	344.00
IUUC-Tme-127004	Tuber melanosporum	34.50	5.00e-103	369.00
IUUC-Tbe-127292	Tupaia belangeri	77.52	0.00e+00	1079.00
IUUC-Ttr-128352	Tursiops truncatus	90.05	0.00e+00	1347.00
IUUC-Vda-129969	Verticillium dahliae	40.44	1.00e-95	344.00
IUUC-Vpa-130218	Vicugna pacos	91.16	0.00e+00	1015.00
IUUC-Xtr-132594	Xenopus tropicalis	76.79	0.00e+00	1184.00
IUUC-Xma-134157	Xiphophorus maculatus	74.35	0.00e+00	1044.00
IUUC-Yli-134470	Yarrowia lipolytica	34.55	2.00e-78	287.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence