iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020230

Ensembl Protein ID

ENSCAFP00000022106.3

UniProt Accession

E2RDH3; E2RDH3_CANLF

Genbank Protein ID

ENSCAFP00000022106

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03002462

Gene Name

TMEM129

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000015011.3	ENSCAFT00000023814.3	ENSCAFP00000022106.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	91.16	0.00e+00	680.00	IUUC-Hsa-046951

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Canis familiaris

Protein Sequence
(Fasta)

MDSPEVTFTL AYLVFAVCFV FTPTEFHSAG LTVQNLLSGW LGSEDAAFVP YHLRRTSATL 60
LCHSLLPLGY YVGMCFAASD KQLYSLGQAP EAWQLFLLLA VTLPTIASTV IYYWSCDQWA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACAGCC CGGAGGTCAC CTTCACGCTG GCCTACTTGG TGTTCGCCGT GTGCTTCGTG 60
TTCACGCCTA CCGAGTTCCA CTCGGCCGGA CTCACGGTGC AGAACCTGCT GTCGGGCTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR018801--Tmpp129

Pfam

PF10272--Tmpp129

Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0016021--C:integral component of membrane
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:0000209--P:protein polyubiquitination
GO:0030970--P:retrograde protein transport, ER to cytosol

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001914	Ailuropoda melanoleuca	97.51	0.00e+00	728.00
IUUC-Apl-003347	Anas platyrhynchos	75.21	5.00e-159	553.00
IUUC-Ame-010846	Astyanax mexicanus	63.87	1.00e-142	499.00
IUUC-Bta-012669	Bos taurus	90.06	0.00e+00	671.00
IUUC-Cel-018636	Caenorhabditis elegans	25.23	8.00e-15	74.70
IUUC-Cja-019250	Callithrix jacchus	87.57	0.00e+00	650.00
IUUC-Cpo-022023	Cavia porcellus	90.33	0.00e+00	673.00
IUUC-Csa-023823	Chlorocebus sabaeus	88.95	0.00e+00	664.00
IUUC-Cin-025745	Ciona intestinalis	43.80	6.00e-92	330.00
IUUC-Csv-025856	Ciona savignyi	42.86	2.00e-91	328.00
IUUC-Dre-028722	Danio rerio	64.64	3.00e-146	511.00
IUUC-Dno-029635	Dasypus novemcinctus	84.18	2.00e-141	494.00
IUUC-Dor-030657	Dipodomys ordii	89.50	0.00e+00	655.00
IUUC-Dme-031679	Drosophila melanogaster	31.96	8.00e-63	234.00
IUUC-Ete-032708	Echinops telfairi	82.30	2.00e-107	381.00
IUUC-Eca-033244	Equus caballus	92.18	2.00e-160	557.00
IUUC-Fca-035762	Felis catus	94.75	0.00e+00	702.00
IUUC-Fal-036939	Ficedula albicollis	76.24	9.00e-167	579.00
IUUC-Fox-038018	Fusarium oxysporum	34.00	2.70e-01	29.60
IUUC-Fso-038434	Fusarium solani	35.29	3.40e+00	27.30
IUUC-Gmo-039282	Gadus morhua	62.50	1.00e-97	348.00
IUUC-Gga-040148	Gallus gallus	75.97	2.00e-166	577.00
IUUC-Gac-042319	Gasterosteus aculeatus	61.14	7.00e-135	473.00
IUUC-Hsa-046951	Homo sapiens	91.16	0.00e+00	680.00
IUUC-Itr-048030	Ictidomys tridecemlineatus	91.16	0.00e+00	679.00
IUUC-Lch-050659	Latimeria chalumnae	73.26	4.00e-164	570.00
IUUC-Loc-052168	Lepisosteus oculatus	71.27	1.00e-163	568.00
IUUC-Laf-054003	Loxodonta africana	87.57	0.00e+00	656.00
IUUC-Mcc-055211	Macaca mulatta	89.23	0.00e+00	666.00
IUUC-Mga-059834	Meleagris gallopavo	74.50	1.00e-133	469.00
IUUC-Mdo-062514	Monodelphis domestica	80.89	2.00e-179	622.00
IUUC-Mmu-063651	Mus musculus	90.88	0.00e+00	654.00
IUUC-Mpu-066843	Mustela putorius furo	97.24	0.00e+00	727.00
IUUC-Mlu-067390	Myotis lucifugus	84.58	1.00e-100	358.00
IUUC-Nle-069501	Nomascus leucogenys	90.33	4.00e-160	556.00
IUUC-Ont-071406	Oreochromis niloticus	61.31	7.00e-134	469.00
IUUC-Oan-073199	Ornithorhynchus anatinus	75.41	3.00e-151	527.00
IUUC-Ola-086495	Oryzias latipes	60.27	5.00e-133	467.00
IUUC-Oga-087914	Otolemur garnettii	91.71	0.00e+00	692.00
IUUC-Oar-089585	Ovis aries	70.03	4.00e-113	400.00
IUUC-Ptr-090660	Pan troglodytes	90.48	3.00e-157	547.00
IUUC-Pan-092206	Papio anubis	89.23	0.00e+00	665.00
IUUC-Psi-093829	Pelodiscus sinensis	76.62	4.00e-168	583.00
IUUC-Pma-094399	Petromyzon marinus	62.64	4.00e-135	474.00
IUUC-Pfo-096826	Poecilia formosa	59.18	4.00e-132	464.00
IUUC-Pab-097827	Pongo abelii	91.44	0.00e+00	683.00
IUUC-Pca-100182	Procavia capensis	87.57	0.00e+00	635.00
IUUC-Pva-103236	Pteropus vampyrus	87.50	4.00e-53	201.00
IUUC-Rno-105429	Rattus norvegicus	91.99	0.00e+00	668.00
IUUC-Sha-107104	Sarcophilus harrisii	79.87	4.00e-147	513.00
IUUC-Ssc-116316	Sus scrofa	90.88	2.00e-180	624.00
IUUC-Tgu-116563	Taeniopygia guttata	75.41	4.00e-165	573.00
IUUC-Tbe-127698	Tupaia belangeri	91.47	2.00e-159	554.00
IUUC-Ttr-128759	Tursiops truncatus	88.12	0.00e+00	641.00
IUUC-Xtr-132390	Xenopus tropicalis	74.86	1.00e-169	588.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence