iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-048049

Ensembl Protein ID

ENSSTOP00000015043.1

UniProt Accession

I3MSE8; I3MSE8_ICTTR

Genbank Protein ID

ENSSTOP00000015043

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01053231

Gene Name

GNB2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000019633.1	ENSSTOT00000023745.1	ENSSTOP00000015043.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.50e-40	135.4	176	214
UBD/Beta-Prp	7.70e-53	179.6	41	264

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH+++v +l++ +d +++vsG+ D +ik+WD+r+  + +
   Q: 176  GHSGDVMSLSLaPDgRTFVSGACDASIKLWDVRDSMCRQ 214
           8***********99999****************988866 PP

UBD/Beta-Prp

   S: 44   llrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee. 131
           + r+l gh a+++a+ +  d+ +lv++s+D+ + +wd  t   vh++   ++ v+++++ psg++++ G+ d++  ++ l+t++     
   Q: 41   TRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIYSLKTREGNVRv 129
           5689*****************************************************************************99877666 PP
   S: 132  ..tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtl 218
              l gh+g  +c ++ + +n ++++s D+t+ lWd++tg+    + g h ++v sls+ ++g+ +vsg++d ++klwd++ + c +t+
   Q: 130  srELPGHTGYLSCCRFLD-DNQIITSSGDTTCALWDIETGQQTVGFAG-HSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTF 216
           779*************99.7778999********************99.**************************************** PP
   S: 219  nghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvi 268
           +gh++ ++ v+f+pn+  + +gs+D + r++dlr ++ l ++++ n  +i
   Q: 217  IGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDN--II 264
           ***************************************9999854..55 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

XRQEAEQLRN QIRDARKACG DSTLTQITAG LDPVGRIQMR TRRTLRGHLA KIYAMHWGTD 60
SRLLVSASQD GKLIIWDSYT TNKVHAIPLR SSWVMTCAYA PSGNFVACGG LDNICSIYSL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNGAGACAGG AGGCCGAGCA GCTCCGGAAC CAGATCCGGG TGAGGGCCTG GCCGGCGGGG 60
ATGGGAAGAG TGAGCAGGCA GGGCCAGACA GCTTGTGTGT GCTGCTGCCC ATTGTCCTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005615--C:extracellular space
GO:0005925--C:focal adhesion
GO:0005765--C:lysosomal membrane
GO:0043209--C:myelin sheath
GO:0048471--C:perinuclear region of cytoplasm
GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001395	Ailuropoda melanoleuca	99.07	0.00e+00	657.00
IUUC-Ago-007831	Ashbya gossypii	38.24	4.00e-68	251.00
IUUC-Ame-011124	Astyanax mexicanus	93.87	0.00e+00	636.00
IUUC-Bta-013430	Bos taurus	100.00	0.00e+00	664.00
IUUC-Bra-016695	Brassica rapa	49.69	1.00e-81	296.00
IUUC-Cel-018704	Caenorhabditis elegans	85.29	4.00e-176	609.00
IUUC-Cja-019794	Callithrix jacchus	100.00	0.00e+00	664.00
IUUC-Cpo-021865	Cavia porcellus	100.00	0.00e+00	663.00
IUUC-Csa-023572	Chlorocebus sabaeus	100.00	0.00e+00	664.00
IUUC-Cin-025309	Ciona intestinalis	80.78	1.00e-167	582.00
IUUC-Csv-026258	Ciona savignyi	81.08	6.00e-168	582.00
IUUC-Cgl-026673	Colletotrichum gloeosporioides	66.37	8.00e-135	473.00
IUUC-Dre-027957	Danio rerio	94.43	0.00e+00	634.00
IUUC-Dno-029001	Dasypus novemcinctus	100.00	0.00e+00	664.00
IUUC-Dor-030322	Dipodomys ordii	88.85	3.00e-166	577.00
IUUC-Eca-034149	Equus caballus	100.00	0.00e+00	664.00
IUUC-Fca-036537	Felis catus	100.00	0.00e+00	664.00
IUUC-Fox-037946	Fusarium oxysporum	66.37	1.00e-129	455.00
IUUC-Fso-038136	Fusarium solani	66.37	1.00e-129	455.00
IUUC-Gmo-039332	Gadus morhua	94.74	0.00e+00	633.00
IUUC-Ggr-039969	Gaeumannomyces graminis	66.07	1.00e-133	468.00
IUUC-Gac-041932	Gasterosteus aculeatus	93.19	0.00e+00	627.00
IUUC-Ggo-044543	Gorilla gorilla	100.00	0.00e+00	664.00
IUUC-Hsa-046432	Homo sapiens	100.00	0.00e+00	664.00
IUUC-Laf-053865	Loxodonta africana	100.00	0.00e+00	663.00
IUUC-Mcc-055781	Macaca mulatta	100.00	0.00e+00	629.00
IUUC-Meu-056902	Macropus eugenii	99.38	0.00e+00	661.00
IUUC-Mor-057188	Magnaporthe oryzae	65.77	6.00e-133	466.00
IUUC-Mpo-057544	Magnaporthe poae	65.77	5.00e-134	470.00
IUUC-Mmr-061015	Microcebus murinus	100.00	0.00e+00	664.00
IUUC-Mdo-062734	Monodelphis domestica	99.38	0.00e+00	661.00
IUUC-Mmu-063737	Mus musculus	100.00	0.00e+00	664.00
IUUC-Mpu-066784	Mustela putorius furo	99.68	0.00e+00	636.00
IUUC-Mlu-067912	Myotis lucifugus	99.69	0.00e+00	663.00
IUUC-Ncr-068650	Neurospora crassa	65.48	8.00e-127	446.00
IUUC-Opr-070866	Ochotona princeps	100.00	0.00e+00	664.00
IUUC-Ont-072526	Oreochromis niloticus	93.50	0.00e+00	628.00
IUUC-Ocu-074344	Oryctolagus cuniculus	100.00	0.00e+00	664.00
IUUC-Ola-087468	Oryzias latipes	90.71	6.00e-178	615.00
IUUC-Oga-089046	Otolemur garnettii	100.00	0.00e+00	664.00
IUUC-Oar-089822	Ovis aries	93.50	5.00e-177	612.00
IUUC-Ptr-091444	Pan troglodytes	100.00	0.00e+00	664.00
IUUC-Pan-092045	Papio anubis	100.00	0.00e+00	664.00
IUUC-Pma-094748	Petromyzon marinus	90.87	5.00e-139	486.00
IUUC-Pab-097601	Pongo abelii	99.07	0.00e+00	659.00
IUUC-Pca-100940	Procavia capensis	100.00	0.00e+00	664.00
IUUC-Pva-102229	Pteropus vampyrus	99.69	0.00e+00	657.00
IUUC-Rno-106104	Rattus norvegicus	100.00	0.00e+00	664.00
IUUC-Sha-107632	Sarcophilus harrisii	99.38	0.00e+00	661.00
IUUC-Ssc-115595	Sus scrofa	100.00	0.00e+00	664.00
IUUC-Tru-118401	Takifugu rubripes	93.19	0.00e+00	627.00
IUUC-Tni-120216	Tetraodon nigroviridis	92.88	0.00e+00	627.00
IUUC-Tre-122156	Trichoderma reesei	66.37	4.00e-134	470.00
IUUC-Tvi-122640	Trichoderma virens	66.37	4.00e-134	470.00
IUUC-Tbe-128132	Tupaia belangeri	99.22	4.00e-148	516.00
IUUC-Ttr-128403	Tursiops truncatus	100.00	0.00e+00	664.00
IUUC-Vda-129855	Verticillium dahliae	70.16	5.00e-129	453.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence