iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-022450

Ensembl Protein ID

ENSCPOP00000006451.2

UniProt Accession

H0V9G1; H0V9G1_CAVPO

Genbank Protein ID

ENSCPOP00000006451

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02005853

Gene Name

IFIH1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000007154.3	ENSCPOT00000007225.2	ENSCPOP00000006451.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/CARD	3.60e-44	149.2	10	82

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/CARD

   S: 3    eeyrlllstlqdrvrklLdvtdvldkylseflleeekelilaaaetkgnmqaaelLLktL....vqkegWfrefl 73
             +r+lls+++ rv+++++v++vld yl+ fl+  +ke+i+++a+t+gnm+a+elLL+tL     +  gW+ref+
   Q: 10   KCFRYLLSCFRTRVKMYIQVEPVLD-YLT-FLPRDVKEQIMRTANTSGNMKAVELLLNTLeqeqGWAPGWTREFV 82
           569**********************.***.******************************777777777888885 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

EMSNAYSTDK CFRYLLSCFR TRVKMYIQVE PVLDYLTFLP RDVKEQIMRT ANTSGNMKAV 60
ELLLNTLEQE QGWAPGWTRE FVDALQRAGS ALAARYVNPD LTDLPSPSFE TTQDECLQLL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGATGTCGA ACGCGTATTC CACGGATAAG TGCTTCCGCT ATCTCCTCTC GTGCTTCAGG 60
ACGCGAGTGA AAATGTACAT CCAGGTAGAG CCCGTGCTGG ACTATCTGAC CTTCCTGCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0862--Zinc

Interpro

IPR031964--CARD_dom
IPR011029--DEATH-like_dom
IPR006935--Helicase/UvrB_N
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR021673--RLR_CTR

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51789--RLR_CTR

Pfam

PF16739--CARD_2
PF00271--Helicase_C
PF04851--ResIII
PF11648--RIG-I_C-RD

SMART

SM00487--DEXDc
SM00490--HELICc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0003677--F:DNA binding
GO:0003725--F:double-stranded RNA binding
GO:0016817--F:hydrolase activity, acting on acid anhydrides
GO:0043021--F:ribonucleoprotein complex binding
GO:0003727--F:single-stranded RNA binding
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0039530--P:MDA-5 signaling pathway
GO:0032727--P:positive regulation of interferon-alpha production
GO:0032728--P:positive regulation of interferon-beta production
GO:0016925--P:protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001336	Ailuropoda melanoleuca	77.01	0.00e+00	1499.00
IUUC-Apl-003900	Anas platyrhynchos	59.71	0.00e+00	1159.00
IUUC-Aca-005329	Anolis carolinensis	57.21	0.00e+00	988.00
IUUC-Ame-011305	Astyanax mexicanus	54.16	0.00e+00	749.00
IUUC-Bta-012361	Bos taurus	77.34	0.00e+00	1461.00
IUUC-Cja-018760	Callithrix jacchus	78.58	0.00e+00	1494.00
IUUC-Cfa-020321	Canis familiaris	75.70	0.00e+00	1457.00
IUUC-Cre-022916	Chlamydomonas reinhardtii	31.62	5.00e-12	67.00
IUUC-Csa-024194	Chlorocebus sabaeus	81.11	0.00e+00	1521.00
IUUC-Cho-024364	Choloepus hoffmanni	67.86	0.00e+00	972.00
IUUC-Dre-028305	Danio rerio	53.61	0.00e+00	703.00
IUUC-Dno-029831	Dasypus novemcinctus	77.88	0.00e+00	1508.00
IUUC-Dor-030410	Dipodomys ordii	71.17	0.00e+00	1148.00
IUUC-Ete-032950	Echinops telfairi	69.98	1.00e-169	590.00
IUUC-Eca-034279	Equus caballus	79.79	0.00e+00	1541.00
IUUC-Eeu-034678	Erinaceus europaeus	74.37	0.00e+00	1447.00
IUUC-Fca-035618	Felis catus	79.47	0.00e+00	898.00
IUUC-Fal-037106	Ficedula albicollis	67.87	0.00e+00	974.00
IUUC-Gmo-038598	Gadus morhua	49.30	0.00e+00	667.00
IUUC-Ggr-039898	Gaeumannomyces graminis	23.35	1.30e-02	35.80
IUUC-Gga-040467	Gallus gallus	58.83	0.00e+00	1115.00
IUUC-Gac-042316	Gasterosteus aculeatus	46.52	0.00e+00	797.00
IUUC-Ggo-045461	Gorilla gorilla	80.53	0.00e+00	1504.00
IUUC-Hsa-045771	Homo sapiens	80.53	0.00e+00	1501.00
IUUC-Itr-048762	Ictidomys tridecemlineatus	79.45	0.00e+00	1522.00
IUUC-Lch-049913	Latimeria chalumnae	63.91	0.00e+00	885.00
IUUC-Loc-052768	Lepisosteus oculatus	52.20	0.00e+00	970.00
IUUC-Laf-053933	Loxodonta africana	76.90	0.00e+00	1474.00
IUUC-Mcc-054695	Macaca mulatta	81.01	0.00e+00	1519.00
IUUC-Meu-056829	Macropus eugenii	68.84	0.00e+00	1035.00
IUUC-Mga-059205	Meleagris gallopavo	59.21	0.00e+00	1113.00
IUUC-Mvi-060497	Microbotryum violaceum	35.77	1.00e-17	86.30
IUUC-Mmr-060703	Microcebus murinus	79.48	0.00e+00	1481.00
IUUC-Mdo-063079	Monodelphis domestica	67.25	0.00e+00	1315.00
IUUC-Mmu-064066	Mus musculus	73.32	0.00e+00	1468.00
IUUC-Mpu-066261	Mustela putorius furo	76.68	0.00e+00	1485.00
IUUC-Mlu-068196	Myotis lucifugus	75.15	0.00e+00	1408.00
IUUC-Nle-069479	Nomascus leucogenys	77.99	0.00e+00	1462.00
IUUC-Opr-070717	Ochotona princeps	70.84	0.00e+00	1069.00
IUUC-Ont-071702	Oreochromis niloticus	46.15	0.00e+00	823.00
IUUC-Oan-073639	Ornithorhynchus anatinus	64.10	0.00e+00	1106.00
IUUC-Ocu-074521	Oryctolagus cuniculus	78.83	0.00e+00	1522.00
IUUC-Ola-086351	Oryzias latipes	46.14	0.00e+00	790.00
IUUC-Oga-088539	Otolemur garnettii	77.29	0.00e+00	1487.00
IUUC-Oar-090186	Ovis aries	76.78	0.00e+00	1442.00
IUUC-Ptr-090575	Pan troglodytes	77.70	0.00e+00	1451.00
IUUC-Pan-092371	Papio anubis	81.21	0.00e+00	1521.00
IUUC-Psi-093072	Pelodiscus sinensis	61.63	0.00e+00	1192.00
IUUC-Pma-094345	Petromyzon marinus	44.38	7.00e-100	357.00
IUUC-Pfo-096401	Poecilia formosa	44.91	0.00e+00	738.00
IUUC-Pab-097623	Pongo abelii	78.97	0.00e+00	1479.00
IUUC-Pca-100993	Procavia capensis	71.34	0.00e+00	1211.00
IUUC-Pva-102227	Pteropus vampyrus	73.81	0.00e+00	1363.00
IUUC-Rno-105198	Rattus norvegicus	72.98	0.00e+00	1450.00
IUUC-Sha-107622	Sarcophilus harrisii	68.04	0.00e+00	1321.00
IUUC-Sar-113625	Sorex araneus	66.72	0.00e+00	694.00
IUUC-Sre-115121	Sporisorium reilianum	26.83	1.20e+00	29.60
IUUC-Tgu-117486	Taeniopygia guttata	57.89	0.00e+00	1076.00
IUUC-Tru-118445	Takifugu rubripes	45.79	0.00e+00	793.00
IUUC-Tsy-119512	Tarsius syrichta	77.41	0.00e+00	1422.00
IUUC-Tni-120711	Tetraodon nigroviridis	44.79	0.00e+00	819.00
IUUC-Tre-122194	Trichoderma reesei	25.13	2.00e-18	88.60
IUUC-Tbe-127644	Tupaia belangeri	70.47	0.00e+00	1323.00
IUUC-Ttr-128989	Tursiops truncatus	73.37	0.00e+00	1429.00
IUUC-Vpa-130587	Vicugna pacos	72.23	0.00e+00	1161.00
IUUC-Xtr-132127	Xenopus tropicalis	52.16	0.00e+00	968.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence