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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Ath-007355
Ensembl Protein ID AT5G61060.1
UniProt Accession Q8RX28; Q9FNQ7; Q9FNQ8; HDA5_ARATH
Genbank Protein ID BAB10369.1; BAB10370.1; AED97417.1; AAM13986.1; AAM53342.1; AAN15392.1
Protein Name Histone deacetylase 5
Genbank Nucleotide ID AB006696; AB006696; CP002688; AY090936; AY120784; BT000073
Gene Name HDA5; At5g61060; MAF19.7
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AT5G61060 AT5G61060.1 AT5G61060.1
AT5G61060 AT5G61060.2 AT5G61060.2
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFAC
Protein-protein Interaction
iRefIndexHINTMentha
Post-translational Modifications (PTMs)
UniProt
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
UBD/ZnF/ZnF_UBP 42.78 4.00e-83 306.00 IUUC-Hsa-046904
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Arabidopsis thaliana
Functional Description
(View)

Functional Description


     Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity).
 Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity).
Protein Sequence
(Fasta)
MAMAGESSGK KIGDCDGKVA GNRQRKVGLI YDETMCKHDT PDGEDHPECP DRIRVIWEKL 60
QLAGVSQRCV VLGSSKAEDK HLQLVHTKDH VNLVKSISTK QKDYRRNRIA SQLNSIYLNG 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ath-007355|UBD,ZnF_UBP|Arabidopsis thaliana
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Nucleotide Sequence
(Fasta)
CTCAAACCTA AAAAAAAAAA AGGAGAGAAT GAAAAAAAGA AAGAATTGAA AAGTAAAAAA 60
TACTTGGAAG CTTTAGAAGC TGAGAGCAAA GACTTGACCT TTTTCACTTC CTTCTCACTG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ath-007355|UBD,ZnF_UBP|Arabidopsis thaliana
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0007--Acetylation
KW-0025--Alternative splicing
KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
Interpro

IPR013024--GGCT-like
IPR000286--His_deacetylse
IPR023801--His_deacetylse_dom
Pfam

PF00850--Hist_deacetyl
PRINTS

PR01270--HDASUPER
Gene Ontology

GO:0005634--C:nucleus
GO:0032041--F:NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated
KEGG ath:AT5G61060
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000749 Aegilops tauschii 59.87 1.00e-113 403.00
IUUC-Aml-002087 Ailuropoda melanoleuca 46.79 1.00e-85 311.00
IUUC-Atr-002745 Amborella trichopoda 53.93 0.00e+00 678.00
IUUC-Apl-003250 Anas platyrhynchos 40.25 1.00e-74 274.00
IUUC-Aca-004303 Anolis carolinensis 43.90 2.00e-84 306.00
IUUC-Aly-006432 Arabidopsis lyrata 92.88 0.00e+00 1248.00
IUUC-Ago-007972 Ashbya gossypii 38.30 1.00e-73 270.00
IUUC-Acl-008187 Aspergillus clavatus 43.15 3.00e-75 275.00
IUUC-Afl-008399 Aspergillus flavus 48.08 2.00e-42 166.00
IUUC-Afu-008954 Aspergillus fumigatus 37.27 2.00e-64 239.00
IUUC-Ani-009142 Aspergillus nidulans 39.63 4.00e-69 255.00
IUUC-Ang-009522 Aspergillus niger 36.13 4.00e-24 105.00
IUUC-Aor-010069 Aspergillus oryzae 40.60 4.00e-67 248.00
IUUC-Ate-010291 Aspergillus terreus 41.29 9.00e-79 287.00
IUUC-Ame-010780 Astyanax mexicanus 40.69 2.00e-80 293.00
IUUC-Bta-013052 Bos taurus 46.88 7.00e-80 291.00
IUUC-Bci-013789 Botrytis cinerea 39.83 7.00e-70 258.00
IUUC-Bdi-014007 Brachypodium distachyon 62.98 2.00e-141 495.00
IUUC-Bol-015468 Brassica oleracea 84.44 0.00e+00 1132.00
IUUC-Bra-016680 Brassica rapa 84.14 0.00e+00 1132.00
IUUC-Cel-018220 Caenorhabditis elegans 38.46 5.00e-73 268.00
IUUC-Cja-019473 Callithrix jacchus 42.78 4.00e-84 305.00
IUUC-Cfa-020263 Canis familiaris 47.09 7.00e-85 308.00
IUUC-Cpo-021691 Cavia porcellus 46.30 3.00e-82 299.00
IUUC-Cre-022561 Chlamydomonas reinhardtii 48.87 2.00e-52 197.00
IUUC-Csa-024223 Chlorocebus sabaeus 42.82 3.00e-84 306.00
IUUC-Csv-026359 Ciona savignyi 44.74 4.00e-58 217.00
IUUC-Cgl-026709 Colletotrichum gloeosporioides 37.28 2.00e-68 252.00
IUUC-Cne-026978 Cryptococcus neoformans 41.48 9.00e-76 277.00
IUUC-Dre-028820 Danio rerio 41.35 7.00e-82 298.00
IUUC-Dno-029160 Dasypus novemcinctus 45.62 3.00e-82 300.00
IUUC-Dor-030859 Dipodomys ordii 45.05 7.00e-85 308.00
IUUC-Dse-031186 Dothistroma septosporum 36.79 8.00e-67 248.00
IUUC-Dme-031963 Drosophila melanogaster 41.14 5.00e-81 295.00
IUUC-Ete-032279 Echinops telfairi 39.14 1.00e-65 244.00
IUUC-Eca-033842 Equus caballus 45.96 1.00e-83 304.00
IUUC-Eeu-034487 Erinaceus europaeus 54.55 2.00e-60 226.00
IUUC-Fca-036430 Felis catus 46.18 1.00e-84 307.00
IUUC-Fox-038067 Fusarium oxysporum 35.24 1.00e-64 240.00
IUUC-Fso-038263 Fusarium solani 37.98 1.00e-69 257.00
IUUC-Gmo-038473 Gadus morhua 41.21 4.00e-68 252.00
IUUC-Ggr-040062 Gaeumannomyces graminis 39.77 2.00e-68 253.00
IUUC-Gga-040501 Gallus gallus 41.86 4.00e-74 272.00
IUUC-Gac-042335 Gasterosteus aculeatus 43.31 3.00e-75 276.00
IUUC-Gma-043738 Glycine max 62.75 0.00e+00 844.00
IUUC-Ggo-045022 Gorilla gorilla 42.78 2.00e-84 307.00
IUUC-Hsa-046904 Homo sapiens 42.78 2.00e-84 306.00
IUUC-Hvu-047285 Hordeum vulgare 64.39 3.00e-137 480.00
IUUC-Itr-048484 Ictidomys tridecemlineatus 44.78 4.00e-87 315.00
IUUC-Kpa-049281 Komagataella pastoris 41.22 2.00e-77 282.00
IUUC-Lch-050330 Latimeria chalumnae 45.18 2.00e-79 290.00
IUUC-Lpe-051214 Leersia perrieri 55.71 0.00e+00 760.00
IUUC-Loc-052231 Lepisosteus oculatus 42.71 7.00e-73 268.00
IUUC-Lma-053263 Leptosphaeria maculans 42.41 1.00e-82 300.00
IUUC-Laf-053386 Loxodonta africana 45.91 7.00e-82 298.00
IUUC-Mcc-055530 Macaca mulatta 42.78 2.00e-84 307.00
IUUC-Meu-056442 Macropus eugenii 45.96 1.00e-85 310.00
IUUC-Mor-057095 Magnaporthe oryzae 41.19 4.00e-75 275.00
IUUC-Mpo-057389 Magnaporthe poae 39.20 5.00e-68 251.00
IUUC-Mtr-058463 Medicago truncatula 62.44 0.00e+00 806.00
IUUC-Mla-059143 Melampsora laricipopulina 42.18 3.00e-77 282.00
IUUC-Mmr-060637 Microcebus murinus 46.60 1.00e-79 291.00
IUUC-Mdo-062198 Monodelphis domestica 45.03 8.00e-84 305.00
IUUC-Mmu-063346 Mus musculus 45.63 3.00e-85 309.00
IUUC-Mac-064630 Musa acuminata 58.87 0.00e+00 806.00
IUUC-Mpu-065884 Mustela putorius furo 47.09 3.00e-85 309.00
IUUC-Mlu-068117 Myotis lucifugus 42.56 2.00e-83 303.00
IUUC-Nfi-068404 Neosartorya fischeri 41.29 5.00e-76 278.00
IUUC-Ncr-068672 Neurospora crassa 37.11 9.00e-68 251.00
IUUC-Nle-069868 Nomascus leucogenys 38.34 5.00e-73 268.00
IUUC-Opr-071074 Ochotona princeps 44.51 5.00e-87 315.00
IUUC-Ont-072246 Oreochromis niloticus 43.23 2.00e-77 283.00
IUUC-Oan-073275 Ornithorhynchus anatinus 42.56 3.00e-76 279.00
IUUC-Ocu-074627 Oryctolagus cuniculus 42.75 1.00e-86 314.00
IUUC-Oba-075489 Oryza barthii 55.71 0.00e+00 674.00
IUUC-Obr-076150 Oryza brachyantha 56.30 0.00e+00 780.00
IUUC-Ogl-077437 Oryza glaberrima 54.97 0.00e+00 763.00
IUUC-Ogu-078370 Oryza glumaepatula 54.68 0.00e+00 763.00
IUUC-Oin-079210 Oryza indica 54.68 0.00e+00 763.00
IUUC-Olo-080971 Oryza longistaminata 53.91 0.00e+00 669.00
IUUC-Oni-082031 Oryza nivara 55.06 0.00e+00 751.00
IUUC-Opu-083471 Oryza punctata 55.43 0.00e+00 733.00
IUUC-Oru-084755 Oryza rufipogon 54.68 0.00e+00 763.00
IUUC-Osa-085447 Oryza sativa 54.68 0.00e+00 763.00
IUUC-Ola-087031 Oryzias latipes 43.41 1.00e-77 284.00
IUUC-Oga-089155 Otolemur garnettii 46.50 7.00e-80 291.00
IUUC-Oar-089620 Ovis aries 46.25 7.00e-80 291.00
IUUC-Ptr-091116 Pan troglodytes 42.97 3.00e-76 279.00
IUUC-Pan-092340 Papio anubis 42.82 2.00e-84 307.00
IUUC-Psi-093734 Pelodiscus sinensis 41.21 3.00e-74 273.00
IUUC-Pma-094386 Petromyzon marinus 42.50 5.00e-75 275.00
IUUC-Pno-095131 Phaeosphaeria nodorum 47.45 2.00e-72 265.00
IUUC-Ppa-095550 Physcomitrella patens 54.77 6.00e-112 397.00
IUUC-Pfo-096110 Poecilia formosa 40.64 5.00e-80 291.00
IUUC-Pab-098422 Pongo abelii 42.31 4.00e-75 276.00
IUUC-Pop-099174 Populus trichocarpa 69.09 0.00e+00 917.00
IUUC-Pca-100833 Procavia capensis 44.24 5.00e-80 292.00
IUUC-Ppe-101644 Prunus persica 66.17 0.00e+00 763.00
IUUC-Pva-102410 Pteropus vampyrus 46.25 2.00e-80 293.00
IUUC-Ptt-103841 Puccinia triticina 40.17 1.00e-72 267.00
IUUC-Pte-104383 Pyrenophora teres 41.32 3.00e-79 289.00
IUUC-Pyt-104427 Pyrenophora triticirepentis 41.32 1.00e-79 290.00
IUUC-Rno-105131 Rattus norvegicus 41.78 6.00e-89 322.00
IUUC-Sce-106274 Saccharomyces cerevisiae 40.76 8.00e-72 264.00
IUUC-Sha-106661 Sarcophilus harrisii 45.22 4.00e-77 282.00
IUUC-Sja-107915 Schizosaccharomyces japonicus 40.49 2.00e-75 276.00
IUUC-Spo-108300 Schizosaccharomyces pombe 42.47 7.00e-73 267.00
IUUC-Smo-109615 Selaginella moellendorffii 49.21 4.00e-171 593.00
IUUC-Sit-110160 Setaria italica 53.50 0.00e+00 738.00
IUUC-Sly-111164 Solanum lycopersicum 58.60 0.00e+00 790.00
IUUC-Stu-112685 Solanum tuberosum 41.01 5.00e-66 244.00
IUUC-Sar-113692 Sorex araneus 38.94 4.00e-57 216.00
IUUC-Sbi-114301 Sorghum bicolor 53.05 0.00e+00 731.00
IUUC-Sre-115013 Sporisorium reilianum 40.41 4.00e-78 285.00
IUUC-Ssc-115724 Sus scrofa 45.65 1.00e-75 277.00
IUUC-Tgu-116776 Taeniopygia guttata 40.25 2.00e-74 273.00
IUUC-Tru-117614 Takifugu rubripes 45.94 3.00e-81 296.00
IUUC-Tsy-118807 Tarsius syrichta 42.28 2.00e-73 270.00
IUUC-Tni-119809 Tetraodon nigroviridis 45.23 7.00e-81 295.00
IUUC-Tca-121312 Theobroma cacao 66.77 0.00e+00 896.00
IUUC-Tre-121930 Trichoderma reesei 38.84 6.00e-69 254.00
IUUC-Tvi-122373 Trichoderma virens 38.08 1.00e-66 247.00
IUUC-Tae-123064 Triticum aestivum 58.01 5.00e-126 443.00
IUUC-Tur-126278 Triticum urartu 32.14 1.20e+00 28.50
IUUC-Tme-127027 Tuber melanosporum 40.77 2.00e-69 255.00
IUUC-Tbe-127675 Tupaia belangeri 40.13 3.00e-22 100.00
IUUC-Ttr-128411 Tursiops truncatus 39.90 1.00e-77 284.00
IUUC-Uma-129408 Ustilago maydis 43.27 6.00e-72 264.00
IUUC-Vda-129994 Verticillium dahliae 37.60 8.00e-68 251.00
IUUC-Vpa-130525 Vicugna pacos 51.67 6.00e-14 72.40
IUUC-Vvi-131038 Vitis vinifera 64.77 0.00e+00 877.00
IUUC-Xtr-132618 Xenopus tropicalis 43.29 1.00e-84 307.00
IUUC-Xma-133730 Xiphophorus maculatus 45.06 1.00e-79 290.00
IUUC-Yli-134680 Yarrowia lipolytica 40.69 3.00e-71 262.00
IUUC-Zma-135110 Zea mays 56.88 9.00e-163 566.00
Created Date 25-Jun-2017

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