iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062198

Ensembl Protein ID

ENSMODP00000012731.2

UniProt Accession

F6TA49; F6TA49_MONDO

Protein Name

Uncharacterized protein

Gene Name

HDAC6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000010166.3	ENSMODT00000012964.3	ENSMODP00000012731.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/ZnF/ZnF_UBP	66.71	0.00e+00	1053.00	IUUC-Hsa-046904

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

KRGVRKGSPI PRASPSLADV RRRGRAKKLS QVSELDLVTD LQDLDLEAGA AVPSGTGLVL 60
DERMSSFHCP WDESFPERPE RLQAVQEQLA RDCLLERCLL IEAQPATPEE LQLVHSQEYV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGCGAGGAG TCCGGAAAGG ATCGCCCATC CCTCGGGCCA GCCCAAGTTT AGCTGATGTC 60
CGACGAAGAG GGAGGGCAAA GAAATTGAGT CAAGTGTCAG AGCTAGATCT GGTGACTGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome

Interpro

IPR000286--His_deacetylse
IPR023801--His_deacetylse_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50271--ZF_UBP

Pfam

PF00850--Hist_deacetyl
PF02148--zf-UBP

PRINTS

PR01270--HDASUPER

SMART

SM00290--ZnF_UBP

Gene Ontology

GO:0016235--C:aggresome
GO:0030424--C:axon
GO:0005901--C:caveola
GO:0031252--C:cell leading edge
GO:0005881--C:cytoplasmic microtubule
GO:0005829--C:cytosol
GO:0030425--C:dendrite
GO:0030286--C:dynein complex
GO:0000118--C:histone deacetylase complex
GO:0043204--C:perikaryon
GO:0048471--C:perinuclear region of cytoplasm
GO:0001047--F:core promoter binding
GO:0004407--F:histone deacetylase activity
GO:0042903--F:tubulin deacetylase activity
GO:0008270--F:zinc ion binding
GO:0070842--P:aggresome assembly
GO:0070301--P:cellular response to hydrogen peroxide
GO:0071218--P:cellular response to misfolded protein
GO:0048668--P:collateral sprouting
GO:0060997--P:dendritic spine morphogenesis
GO:0070846--P:Hsp90 deacetylation
GO:0032418--P:lysosome localization
GO:0006515--P:misfolded or incompletely synthesized protein catabolic process
GO:0051646--P:mitochondrion localization
GO:0007026--P:negative regulation of microtubule depolymerization
GO:0045861--P:negative regulation of proteolysis
GO:0061734--P:parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
GO:0034983--P:peptidyl-lysine deacetylation
GO:0070845--P:polyubiquitinated misfolded protein transport
GO:0090035--P:positive regulation of chaperone-mediated protein complex assembly
GO:0010634--P:positive regulation of epithelial cell migration
GO:1901300--P:positive regulation of hydrogen peroxide-mediated programmed cell death
GO:0010870--P:positive regulation of receptor biosynthetic process
GO:0009967--P:positive regulation of signal transduction
GO:0043241--P:protein complex disassembly
GO:0000209--P:protein polyubiquitination
GO:0070201--P:regulation of establishment of protein localization
GO:0045598--P:regulation of fat cell differentiation
GO:0040029--P:regulation of gene expression, epigenetic
GO:0031647--P:regulation of protein stability
GO:0010469--P:regulation of receptor activity
GO:0070848--P:response to growth factor
GO:0009636--P:response to toxic substance
GO:0043162--P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000749	Aegilops tauschii	40.94	6.00e-69	255.00
IUUC-Aml-002087	Ailuropoda melanoleuca	67.44	0.00e+00	1122.00
IUUC-Atr-002745	Amborella trichopoda	42.36	8.00e-83	301.00
IUUC-Apl-003250	Anas platyrhynchos	42.96	1.00e-78	288.00
IUUC-Aca-004303	Anolis carolinensis	60.86	0.00e+00	1036.00
IUUC-Aly-006432	Arabidopsis lyrata	44.48	2.00e-80	293.00
IUUC-Ath-007355	Arabidopsis thaliana	45.03	9.00e-85	307.00
IUUC-Ago-007972	Ashbya gossypii	40.62	4.00e-81	296.00
IUUC-Acl-008187	Aspergillus clavatus	43.11	2.00e-83	303.00
IUUC-Afl-008399	Aspergillus flavus	47.98	5.00e-49	188.00
IUUC-Afu-008954	Aspergillus fumigatus	37.88	7.00e-71	261.00
IUUC-Ani-009142	Aspergillus nidulans	42.51	7.00e-77	281.00
IUUC-Ang-009522	Aspergillus niger	29.95	1.00e-39	158.00
IUUC-Aor-010069	Aspergillus oryzae	40.81	2.00e-73	270.00
IUUC-Ate-010291	Aspergillus terreus	43.01	3.00e-84	306.00
IUUC-Ame-010780	Astyanax mexicanus	50.75	0.00e+00	776.00
IUUC-Bta-013052	Bos taurus	59.49	0.00e+00	1228.00
IUUC-Bci-013789	Botrytis cinerea	40.41	3.00e-76	280.00
IUUC-Bdi-014007	Brachypodium distachyon	43.25	1.00e-86	314.00
IUUC-Bol-015468	Brassica oleracea	45.71	4.00e-83	302.00
IUUC-Bra-016680	Brassica rapa	45.98	1.00e-83	304.00
IUUC-Cel-018220	Caenorhabditis elegans	39.92	5.00e-155	541.00
IUUC-Cja-019473	Callithrix jacchus	64.22	0.00e+00	1044.00
IUUC-Cfa-020263	Canis familiaris	58.89	0.00e+00	1253.00
IUUC-Cpo-021691	Cavia porcellus	67.24	0.00e+00	1121.00
IUUC-Cre-022561	Chlamydomonas reinhardtii	53.10	2.00e-54	204.00
IUUC-Csa-024223	Chlorocebus sabaeus	66.99	0.00e+00	1095.00
IUUC-Csv-026359	Ciona savignyi	47.81	2.00e-57	216.00
IUUC-Cgl-026709	Colletotrichum gloeosporioides	41.18	1.00e-79	291.00
IUUC-Cne-026978	Cryptococcus neoformans	42.33	6.00e-84	305.00
IUUC-Dre-028820	Danio rerio	56.65	0.00e+00	929.00
IUUC-Dno-029160	Dasypus novemcinctus	55.94	0.00e+00	1168.00
IUUC-Dor-030859	Dipodomys ordii	66.34	0.00e+00	1131.00
IUUC-Dse-031186	Dothistroma septosporum	40.35	9.00e-78	285.00
IUUC-Dme-031963	Drosophila melanogaster	44.75	0.00e+00	716.00
IUUC-Ete-032279	Echinops telfairi	54.57	2.00e-126	447.00
IUUC-Eca-033842	Equus caballus	67.56	0.00e+00	1119.00
IUUC-Eeu-034487	Erinaceus europaeus	60.88	8.00e-119	421.00
IUUC-Fca-036430	Felis catus	68.10	0.00e+00	1100.00
IUUC-Fox-038067	Fusarium oxysporum	42.82	3.00e-81	296.00
IUUC-Fso-038263	Fusarium solani	42.31	2.00e-82	300.00
IUUC-Gmo-038473	Gadus morhua	39.27	2.00e-71	264.00
IUUC-Ggr-040062	Gaeumannomyces graminis	42.17	1.00e-73	271.00
IUUC-Gga-040501	Gallus gallus	42.96	4.00e-78	286.00
IUUC-Gac-042335	Gasterosteus aculeatus	40.64	2.00e-78	287.00
IUUC-Gma-043738	Glycine max	44.32	5.00e-82	298.00
IUUC-Ggo-045022	Gorilla gorilla	66.58	0.00e+00	1097.00
IUUC-Hsa-046904	Homo sapiens	66.71	0.00e+00	1095.00
IUUC-Hvu-047285	Hordeum vulgare	46.18	4.00e-83	301.00
IUUC-Itr-048484	Ictidomys tridecemlineatus	68.01	0.00e+00	1162.00
IUUC-Kpa-049281	Komagataella pastoris	41.01	3.00e-81	296.00
IUUC-Lch-050330	Latimeria chalumnae	52.21	0.00e+00	823.00
IUUC-Lpe-051214	Leersia perrieri	45.87	7.00e-85	308.00
IUUC-Loc-052231	Lepisosteus oculatus	43.93	9.00e-79	288.00
IUUC-Lma-053263	Leptosphaeria maculans	42.86	3.00e-87	316.00
IUUC-Laf-053386	Loxodonta africana	58.50	0.00e+00	1239.00
IUUC-Mcc-055530	Macaca mulatta	66.83	0.00e+00	1093.00
IUUC-Meu-056442	Macropus eugenii	85.57	0.00e+00	1181.00
IUUC-Mor-057095	Magnaporthe oryzae	42.71	2.00e-84	307.00
IUUC-Mpo-057389	Magnaporthe poae	42.45	4.00e-74	272.00
IUUC-Mtr-058463	Medicago truncatula	44.44	2.00e-88	319.00
IUUC-Mla-059143	Melampsora laricipopulina	37.26	1.00e-80	294.00
IUUC-Mmr-060637	Microcebus murinus	64.54	0.00e+00	1083.00
IUUC-Mmu-063346	Mus musculus	58.33	0.00e+00	1258.00
IUUC-Mac-064630	Musa acuminata	42.40	3.00e-80	293.00
IUUC-Mpu-065884	Mustela putorius furo	59.54	0.00e+00	1292.00
IUUC-Mlu-068117	Myotis lucifugus	65.20	0.00e+00	1073.00
IUUC-Nfi-068404	Neosartorya fischeri	43.11	1.00e-83	304.00
IUUC-Ncr-068672	Neurospora crassa	41.90	3.00e-81	296.00
IUUC-Nle-069868	Nomascus leucogenys	68.65	1.00e-161	563.00
IUUC-Opr-071074	Ochotona princeps	64.36	2.00e-174	606.00
IUUC-Ont-072246	Oreochromis niloticus	54.11	0.00e+00	796.00
IUUC-Oan-072911	Ornithorhynchus anatinus	67.33	3.00e-120	426.00
IUUC-Ocu-074627	Oryctolagus cuniculus	67.04	0.00e+00	1128.00
IUUC-Oba-075489	Oryza barthii	45.59	5.00e-84	305.00
IUUC-Obr-076150	Oryza brachyantha	46.34	5.00e-85	308.00
IUUC-Ogl-077437	Oryza glaberrima	45.59	3.00e-84	306.00
IUUC-Ogu-078370	Oryza glumaepatula	45.59	8.00e-85	308.00
IUUC-Oin-079210	Oryza indica	45.59	8.00e-85	308.00
IUUC-Olo-080971	Oryza longistaminata	46.64	2.00e-74	273.00
IUUC-Oni-082031	Oryza nivara	45.59	1.00e-84	307.00
IUUC-Opu-083471	Oryza punctata	44.98	6.00e-84	305.00
IUUC-Oru-084755	Oryza rufipogon	45.59	7.00e-85	308.00
IUUC-Osa-085447	Oryza sativa	45.59	8.00e-85	308.00
IUUC-Ola-087031	Oryzias latipes	40.77	5.00e-77	282.00
IUUC-Oga-089155	Otolemur garnettii	66.34	0.00e+00	1068.00
IUUC-Oar-089620	Ovis aries	67.12	0.00e+00	1070.00
IUUC-Ptr-090812	Pan troglodytes	64.77	0.00e+00	941.00
IUUC-Pan-092340	Papio anubis	66.83	0.00e+00	1092.00
IUUC-Psi-093734	Pelodiscus sinensis	42.57	3.00e-76	280.00
IUUC-Pma-094386	Petromyzon marinus	53.17	0.00e+00	804.00
IUUC-Pno-095131	Phaeosphaeria nodorum	47.90	5.00e-75	275.00
IUUC-Ppa-095550	Physcomitrella patens	46.56	9.00e-85	308.00
IUUC-Pfo-096110	Poecilia formosa	55.29	0.00e+00	730.00
IUUC-Pab-098422	Pongo abelii	66.34	0.00e+00	1058.00
IUUC-Pop-099174	Populus trichocarpa	44.32	6.00e-82	298.00
IUUC-Pca-100833	Procavia capensis	58.82	0.00e+00	1221.00
IUUC-Ppe-101644	Prunus persica	43.49	1.00e-85	310.00
IUUC-Pva-102410	Pteropus vampyrus	61.25	0.00e+00	966.00
IUUC-Ptt-103841	Puccinia triticina	37.09	7.00e-76	278.00
IUUC-Pte-104383	Pyrenophora teres	41.22	7.00e-84	305.00
IUUC-Pyt-104427	Pyrenophora triticirepentis	41.71	2.00e-84	307.00
IUUC-Rno-105131	Rattus norvegicus	68.02	0.00e+00	1151.00
IUUC-Sce-106274	Saccharomyces cerevisiae	40.68	2.00e-78	286.00
IUUC-Sha-106661	Sarcophilus harrisii	64.62	0.00e+00	1224.00
IUUC-Sja-107915	Schizosaccharomyces japonicus	41.11	6.00e-84	305.00
IUUC-Spo-108300	Schizosaccharomyces pombe	43.48	1.00e-82	301.00
IUUC-Smo-109615	Selaginella moellendorffii	45.78	1.00e-83	303.00
IUUC-Sit-110160	Setaria italica	45.40	4.00e-79	289.00
IUUC-Sly-111164	Solanum lycopersicum	40.00	2.00e-82	300.00
IUUC-Stu-112685	Solanum tuberosum	44.16	2.00e-74	273.00
IUUC-Sar-113692	Sorex araneus	52.60	1.00e-172	600.00
IUUC-Sbi-114301	Sorghum bicolor	45.29	7.00e-79	288.00
IUUC-Sre-115013	Sporisorium reilianum	44.10	4.00e-83	302.00
IUUC-Ssc-115724	Sus scrofa	62.12	0.00e+00	1256.00
IUUC-Tgu-116605	Taeniopygia guttata	47.80	0.00e+00	671.00
IUUC-Tru-117614	Takifugu rubripes	55.24	0.00e+00	862.00
IUUC-Tsy-118807	Tarsius syrichta	62.80	2.00e-165	576.00
IUUC-Tni-119809	Tetraodon nigroviridis	57.00	0.00e+00	811.00
IUUC-Tca-121312	Theobroma cacao	43.65	2.00e-82	300.00
IUUC-Tre-121930	Trichoderma reesei	42.97	1.00e-86	314.00
IUUC-Tvi-122373	Trichoderma virens	42.48	3.00e-85	309.00
IUUC-Tae-123064	Triticum aestivum	40.56	2.00e-75	275.00
IUUC-Tme-127027	Tuber melanosporum	41.80	4.00e-72	265.00
IUUC-Tbe-127675	Tupaia belangeri	68.26	3.00e-57	217.00
IUUC-Ttr-128411	Tursiops truncatus	65.60	0.00e+00	1092.00
IUUC-Uma-129408	Ustilago maydis	46.13	4.00e-79	289.00
IUUC-Vda-129994	Verticillium dahliae	40.62	4.00e-76	279.00
IUUC-Vpa-130525	Vicugna pacos	57.73	3.00e-35	143.00
IUUC-Vvi-131038	Vitis vinifera	41.94	3.00e-82	299.00
IUUC-Xtr-132618	Xenopus tropicalis	60.81	0.00e+00	998.00
IUUC-Xma-133730	Xiphophorus maculatus	50.06	0.00e+00	734.00
IUUC-Yli-134680	Yarrowia lipolytica	39.75	6.00e-81	295.00
IUUC-Zma-135110	Zea mays	41.74	4.00e-78	285.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence