iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-034191

UUCD1 version

UUC-EqC-00608

Ensembl Protein ID

ENSECAP00000023018.1

UniProt Accession

F6ZV22; F6ZV22_HORSE

Protein Name

Uncharacterized protein

Gene Name

KLHL11

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000021494.2	ENSECAT00000029131.1	ENSECAP00000023018.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.70e-15	57.3	61	135
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	5.30e-10	38.4	169	200

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvg...geeffahkivLaasSsvFyalflmeleesksklmveikd......vqpevfrallkFlYtgklde 67
           +D++l+ g   g+ef+ah++vLa++ ++F  l++++++es+ +++ve++        +p+ ++a+++++Ytg+++ 
   Q: 61   CDITLCFGgagGREFRAHRSVLARATEYFTPLLSGQFSESR-SGRVEMRKwssepgPEPDTVEAVIEYMYTGRIRV 135
           8******7788******************************.*******4456799*****************975 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           l+Nc++i ++A++y++++L+++a d+i ++F+
   Q: 169  LSNCVAIHSLAHMYTLSQLALKAADMIRRNFH 200
           69*****************************8 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

TEGVTFELRG SGMVPGRPKW GRRAKARGGD PGPRGEDFEC SSHCSELSWR QNEQRRKGLF 60
CDITLCFGGA GGREFRAHRS VLARATEYFT PLLSGQFSES RSGRVEMRKW SSEPGPEPDT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACAGAAGGGG TAACATTTGA GCTGAGGGGG AGTGGGATGG TGCCCGGGAG ACCTAAGTGG 60
GGAAGGAGGT GAGCAAAGGC CAGAGGTGTG TAAGTTCACA AGGTGTGTAA GGAGCAGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0031625--F:ubiquitin protein ligase binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0030162--P:regulation of proteolysis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002239	Ailuropoda melanoleuca	96.93	0.00e+00	1316.00
IUUC-Apl-003928	Anas platyrhynchos	84.42	0.00e+00	1034.00
IUUC-Aca-004801	Anolis carolinensis	81.80	0.00e+00	1097.00
IUUC-Ame-010943	Astyanax mexicanus	76.36	0.00e+00	912.00
IUUC-Bta-012341	Bos taurus	100.00	5.00e-97	345.00
IUUC-Cja-019924	Callithrix jacchus	96.42	0.00e+00	1347.00
IUUC-Cfa-021076	Canis familiaris	96.87	0.00e+00	1355.00
IUUC-Cpo-022193	Cavia porcellus	92.77	0.00e+00	1250.00
IUUC-Csa-023614	Chlorocebus sabaeus	96.72	0.00e+00	1349.00
IUUC-Cho-024806	Choloepus hoffmanni	81.92	0.00e+00	906.00
IUUC-Dre-028622	Danio rerio	74.84	0.00e+00	993.00
IUUC-Dno-029965	Dasypus novemcinctus	93.77	0.00e+00	1306.00
IUUC-Dor-030136	Dipodomys ordii	98.29	0.00e+00	1090.00
IUUC-Eeu-034746	Erinaceus europaeus	95.67	0.00e+00	1341.00
IUUC-Fca-035702	Felis catus	89.91	0.00e+00	1222.00
IUUC-Fal-037360	Ficedula albicollis	84.03	0.00e+00	1025.00
IUUC-Gmo-038582	Gadus morhua	75.93	0.00e+00	998.00
IUUC-Ggr-039747	Gaeumannomyces graminis	25.93	2.00e-08	52.40
IUUC-Gga-040375	Gallus gallus	84.01	0.00e+00	1124.00
IUUC-Gac-042523	Gasterosteus aculeatus	76.34	0.00e+00	991.00
IUUC-Ggo-045632	Gorilla gorilla	98.86	0.00e+00	1095.00
IUUC-Hsa-046817	Homo sapiens	96.72	0.00e+00	1350.00
IUUC-Itr-048433	Ictidomys tridecemlineatus	96.57	0.00e+00	1353.00
IUUC-Lch-049985	Latimeria chalumnae	78.86	0.00e+00	1036.00
IUUC-Loc-052594	Lepisosteus oculatus	75.61	0.00e+00	991.00
IUUC-Lma-053111	Leptosphaeria maculans	31.65	7.00e-05	40.80
IUUC-Laf-054357	Loxodonta africana	96.87	0.00e+00	1356.00
IUUC-Mcc-055454	Macaca mulatta	98.16	0.00e+00	1341.00
IUUC-Meu-056012	Macropus eugenii	94.00	1.00e-168	585.00
IUUC-Mga-060048	Meleagris gallopavo	85.54	0.00e+00	863.00
IUUC-Mdo-062082	Monodelphis domestica	91.51	0.00e+00	1259.00
IUUC-Mmu-063119	Mus musculus	94.93	0.00e+00	1334.00
IUUC-Mpu-066511	Mustela putorius furo	96.72	0.00e+00	1355.00
IUUC-Mlu-067301	Myotis lucifugus	98.27	0.00e+00	1316.00
IUUC-Nfi-068503	Neosartorya fischeri	33.33	1.00e-03	37.00
IUUC-Nle-069912	Nomascus leucogenys	96.72	0.00e+00	1350.00
IUUC-Opr-070762	Ochotona princeps	97.53	0.00e+00	838.00
IUUC-Ont-071916	Oreochromis niloticus	77.36	0.00e+00	994.00
IUUC-Oan-072932	Ornithorhynchus anatinus	76.85	0.00e+00	818.00
IUUC-Ocu-074172	Oryctolagus cuniculus	99.23	0.00e+00	1086.00
IUUC-Ola-086483	Oryzias latipes	77.05	0.00e+00	990.00
IUUC-Oga-088112	Otolemur garnettii	95.54	0.00e+00	1310.00
IUUC-Oar-090129	Ovis aries	96.57	0.00e+00	1355.00
IUUC-Ptr-090571	Pan troglodytes	98.86	0.00e+00	1093.00
IUUC-Pan-092073	Papio anubis	96.87	0.00e+00	1352.00
IUUC-Psi-093836	Pelodiscus sinensis	86.25	0.00e+00	1078.00
IUUC-Pno-095007	Phaeosphaeria nodorum	31.08	5.00e-05	41.60
IUUC-Pfo-096477	Poecilia formosa	77.21	0.00e+00	991.00
IUUC-Pab-098473	Pongo abelii	96.57	0.00e+00	1349.00
IUUC-Pca-100239	Procavia capensis	94.38	0.00e+00	788.00
IUUC-Pte-104232	Pyrenophora teres	35.62	5.00e-05	41.60
IUUC-Pyt-104638	Pyrenophora triticirepentis	35.62	4.00e-05	41.60
IUUC-Rno-104859	Rattus norvegicus	95.08	0.00e+00	1338.00
IUUC-Sha-106746	Sarcophilus harrisii	91.72	0.00e+00	1244.00
IUUC-Tgu-117183	Taeniopygia guttata	83.15	0.00e+00	1122.00
IUUC-Tru-118655	Takifugu rubripes	75.23	0.00e+00	981.00
IUUC-Tsy-119430	Tarsius syrichta	98.59	0.00e+00	1322.00
IUUC-Tni-119698	Tetraodon nigroviridis	76.25	0.00e+00	865.00
IUUC-Vda-129848	Verticillium dahliae	33.33	7.00e-04	37.70
IUUC-Vpa-130715	Vicugna pacos	95.27	0.00e+00	1336.00
IUUC-Xtr-132276	Xenopus tropicalis	76.91	0.00e+00	988.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence