iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
FBgn0028496	FBtr0086718	FBpp0085897
FBgn0028496	FBtr0086721	FBpp0085900
FBgn0028496	FBtr0086720	FBpp0085899

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.80e-43	144.1	1252	1283
UBD/Beta-Prp	7.60e-89	297.8	1311	1503

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           gHt++v+cl+f ++  +l++Gs D  +++W+l
   Q: 1252 GHTAGVSCLKFaPNgEFLATGSEDRLVHIWNL 1283
           8***********777****************7 PP

UBD/Beta-Prp

   S: 25   latgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirv 120
           ++++ rd+++ vw +++g+ll++++g     ++++  ++  + v++  D+t+k+w+l + +  ++++ h+d++++ ++s+++ +++sGs+d  ++v
   Q: 1311 VISTDRDSMLLVWMAHSGNLLQTIQGPY---KSLSVTNNMRFAVSTNGDNTLKIWSLTQEDEKYSVS-HSDEITCFEISADSVHIISGSRDMSLKV 1402
           7999****************77776655...9999999999**************************.**************************** PP
   S: 121  wdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecv 215
           w+   g+ ++ +l gh+++v+cv+v+ ++   + sGs+D  + lWdl tg+ ++tl g h ++v  ++++ +g   vsgs+d+t+++w+ ++g  +
   Q: 1403 WQATGGKLSQ-VLVGHSDAVTCVAVSVTNkTQVLSGSKDMNLILWDLLTGEEVHTLAG-HLGPVIGVKVSADGSTAVSGSDDKTLIVWETKRGLAL 1496
           ***9999999.******************999************************99.***********************************99 PP
   S: 216  rtlnght 222
            +l+ h 
   Q: 1497 TSLQMHV 1503
           9999886 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MAAPIDESVL NALRGVTSAH TRLPKPLLIK IYVASLKQEF NQERRMLLEL VGPELQSLYD 60
DRQIELEFVD MHFGTGDLEV HQLERDPYLI HDYLHEIDTC HAHTKSVFFM VLVGDGIGRQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCAGTTCCT CGTCGAAGTT GAAAGCGTTT GGTGCTCGCA GCGGAAAAGC GAATCTGGCG 60
GCACCCAAAC AAATATTAAG AAAAAAAAAT GAATAAATAA GGAAAAGCTG GGGAAAACTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR027417--P-loop_NTPase
IPR002469--Peptidase_S9B_N
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cel-018376	Caenorhabditis elegans	23.50	1.00e-97	351.00
IUUC-Dre-028241	Danio rerio	23.78	3.00e-12	67.40
IUUC-Ggr-039828	Gaeumannomyces graminis	24.49	3.00e-39	157.00
IUUC-Loc-052039	Lepisosteus oculatus	21.89	1.00e-35	145.00
IUUC-Oan-073437	Ornithorhynchus anatinus	21.44	6.00e-24	105.00
IUUC-Oga-088313	Otolemur garnettii	24.22	4.00e-15	77.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence