iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
Protein-protein Interaction
iRefIndex	PINA	HINT	Mentha
Post-translational Modifications (PTMs)
dbPPT	UniProt
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.90e-08	34.6	196	245

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           +vC  Cg+++ +++  ++C+ C++wfH +C+k++   + +  +++ Cp+C+
   Q: 196  AVCGACGDNYGGDEFWICCDACEKWFHGKCVKIT-PAKAEHIKHYKCPSCT 245
           6899*********99999999*************.888888888******7 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Histone-binding component that specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes.

Protein Sequence
(Fasta)

MEGIQHPIPR TVEEVFSDFR GRRAGLIKAL STDVQKFYHQ CDPEKENLCL YGLPNETWEV 60
NLPVEEVPPE LPEPALGINF ARDGMQEKDW ISLVAVHSDS WLISVAFYFG ARFGFGKNER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGATAAATAC AGGTTGTGAC TTTAAAAAAA AAAAAAAAAA GTTGAGATGT TGTCGCTTTA 60
ATCTATTCTT CCAATGCTTC CAAATCCCTC AAATTGTCTT TTGTCTCCTT TCCTTTTCGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR021998--Alfin
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12165--Alfin
PF00628--PHD

SMART

SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0035064--F:methylated histone binding
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated

KEGG

ath:AT1G14510

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001165	Aegilops tauschii	50.58	4.00e-61	227.00
IUUC-Atr-002983	Amborella trichopoda	67.21	2.00e-83	301.00
IUUC-Aly-005868	Arabidopsis lyrata	96.83	2.00e-114	403.00
IUUC-Acl-008106	Aspergillus clavatus	44.90	1.00e-06	48.10
IUUC-Afu-008783	Aspergillus fumigatus	47.83	7.00e-07	48.90
IUUC-Ani-009326	Aspergillus nidulans	48.78	3.00e-06	46.60
IUUC-Ang-009560	Aspergillus niger	58.82	3.00e-06	47.00
IUUC-Bdi-014599	Brachypodium distachyon	67.47	2.00e-78	284.00
IUUC-Bol-015206	Brassica oleracea	80.32	7.00e-95	338.00
IUUC-Bra-016659	Brassica rapa	80.72	2.00e-95	340.00
IUUC-Csv-026156	Ciona savignyi	54.05	4.00e-08	52.40
IUUC-Cgl-026411	Colletotrichum gloeosporioides	46.34	8.00e-06	43.90
IUUC-Cne-026898	Cryptococcus neoformans	52.78	6.00e-06	46.60
IUUC-Dse-031262	Dothistroma septosporum	51.22	5.00e-06	46.20
IUUC-Fox-037812	Fusarium oxysporum	45.00	4.00e-05	42.00
IUUC-Ggr-039960	Gaeumannomyces graminis	51.16	2.00e-06	46.60
IUUC-Gma-043342	Glycine max	64.52	5.00e-79	286.00
IUUC-Hvu-047100	Hordeum vulgare	57.08	4.00e-69	253.00
IUUC-Kpa-049384	Komagataella pastoris	36.54	1.00e-05	44.30
IUUC-Lpe-050738	Leersia perrieri	59.67	1.00e-69	255.00
IUUC-Meu-056467	Macropus eugenii	38.89	9.00e-04	39.70
IUUC-Mor-057044	Magnaporthe oryzae	46.67	7.00e-06	44.70
IUUC-Mpo-057588	Magnaporthe poae	51.22	7.00e-06	45.10
IUUC-Mtr-057868	Medicago truncatula	65.34	1.00e-77	281.00
IUUC-Mvi-060256	Microbotryum violaceum	36.17	6.00e-05	42.40
IUUC-Mac-064462	Musa acuminata	60.42	2.00e-71	261.00
IUUC-Nfi-068438	Neosartorya fischeri	47.83	7.00e-07	48.90
IUUC-Oba-075021	Oryza barthii	55.34	1.00e-62	232.00
IUUC-Ogl-077422	Oryza glaberrima	58.85	1.00e-63	234.00
IUUC-Ogu-079021	Oryza glumaepatula	55.34	1.00e-62	232.00
IUUC-Oin-079801	Oryza indica	59.67	1.00e-63	235.00
IUUC-Olo-080963	Oryza longistaminata	45.70	3.00e-26	110.00
IUUC-Ome-081881	Oryza meridionalis	58.85	4.00e-63	233.00
IUUC-Oni-082314	Oryza nivara	59.67	1.00e-63	235.00
IUUC-Opu-083359	Oryza punctata	59.26	7.00e-64	236.00
IUUC-Oru-085108	Oryza rufipogon	58.02	6.00e-61	226.00
IUUC-Osa-085794	Oryza sativa	82.84	5.00e-54	203.00
IUUC-Olu-087829	Ostreococcus lucimarinus	65.65	4.00e-40	157.00
IUUC-Ppa-095203	Physcomitrella patens	62.92	2.00e-71	261.00
IUUC-Pop-099708	Populus trichocarpa	79.44	3.00e-100	357.00
IUUC-Ppe-101390	Prunus persica	67.60	2.00e-79	287.00
IUUC-Sce-106445	Saccharomyces cerevisiae	32.81	5.00e-04	38.50
IUUC-Spo-108245	Schizosaccharomyces pombe	44.19	3.00e-05	42.40
IUUC-Smo-109237	Selaginella moellendorffii	51.67	1.00e-50	191.00
IUUC-Sit-110822	Setaria italica	81.34	3.00e-53	201.00
IUUC-Sly-111474	Solanum lycopersicum	77.02	7.00e-94	335.00
IUUC-Stu-112822	Solanum tuberosum	76.92	6.00e-93	332.00
IUUC-Tca-121742	Theobroma cacao	76.40	7.00e-91	325.00
IUUC-Tre-122185	Trichoderma reesei	48.78	1.00e-05	43.50
IUUC-Tvi-122269	Trichoderma virens	51.22	9.00e-06	43.90
IUUC-Tae-124016	Triticum aestivum	62.55	6.00e-75	273.00
IUUC-Uma-129637	Ustilago maydis	42.86	2.00e-05	44.30
IUUC-Vda-129733	Verticillium dahliae	42.86	3.00e-04	41.20
IUUC-Vvi-131388	Vitis vinifera	76.40	3.00e-93	333.00
IUUC-Yli-134626	Yarrowia lipolytica	36.54	1.00e-04	40.80
IUUC-Zma-134690	Zea mays	54.15	4.00e-54	204.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence