iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Acl-008254

Ensembl Protein ID

CADACLAP00004716

UniProt Accession

A1CI18; A1CI18_ASPCL

Genbank Protein ID

EAW10523.1

Protein Name

Ubiquitin-protein ligase (Tom1), putative

Genbank Nucleotide ID

DS027054

Gene Name

ACLA_049950

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADACLAG00004817	CADACLAT00004817	CADACLAP00004716

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.20e-119	397.7	3724	4056

Active Site

Position(s)	Description	Evidence
4025	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkk.rlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlpl 92
           ++lk+ +l+v+f gEeg+d+gGvtre+++ l++ ++np++ lf   + d++t++pn+ sg+ n ehl +F+f+Gr++gkal++gr+ld+++
   Q: 3724 DELKYgKLNVRFHGEEGVDAGGVTREWFQVLARGMFNPNYALFIPVAADRTTFHPNRLSGV-NSEHLMFFKFIGRIIGKALYEGRVLDCHF 3813
           567755999***************************************************9.56*************************** PP
   S: 93   sksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlk 183
           s+++yk++l++++s++d+e++d ++yksl +++en   di+++ ++ tf v+++ +ge ++ +L+++G+nipVt+eNkeeYv++vv+yrl 
   Q: 3814 SRAVYKCILSRSVSIKDMETLDLDYYKSLLWMLEN---DITDI-ITETFAVETDDFGEKQVIDLIENGSNIPVTQENKEEYVQRVVDYRLV 3900
           *********************************99...99999.999******************************************** PP
   S: 184  egikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrl 274
           +++k q+++f +Gf+e+ip++l+s+F+e+elelli+G +eidv+d+k++t+y++ y+++sp+iqwFw+++++f++eer+++LqFvTg+s++
   Q: 3901 KSVKDQLDNFLNGFHEIIPPDLISIFNEQELELLISGLPEIDVDDWKANTEYHN-YSASSPQIQWFWRAVRSFDKEERAKLLQFVTGTSKV 3990
           ****************************************************66.************************************ PP
   S: 275  PlgGfaelk....prlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFe 334
           Pl+Gf+el+     ++f i++ ++++drlPss+TCfn+L+LPeY+++e+l+++L +Ai+ + + F+
   Q: 3991 PLNGFKELEgmngVSKFNIHRdYGNKDRLPSSHTCFNQLDLPEYENYETLRQRLYTAITAGsEYFG 4056
           *********99997778888878889*********************************9977776 PP

Organism

Aspergillus clavatus

Protein Sequence
(Fasta)

MGRIKKAASQ KHEATISPYL TDFVARATSV PIPELPTHLN TFSRLWPFPR GDLYHWINVL 60
NRFDEILASV IEKYALNAGP QTKPFGRHVL VDSYATGESQ TSPEDADTKL DALGYGPEGD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGAGAA TCAAGAAAGC GGCGAGCCAG AAGCATGAGG CGACAATTGT AAGTTTCTCA 60
CCCCCGCTTG CTCTTCCAGC ATGAGGATGA AGGCTGACGA AAAAATTTCC TCCCCACTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR025527--DUF4414
IPR010309--E3_Ub_ligase_DUF908
IPR010314--E3_Ub_ligase_DUF913
IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF14377--DUF4414
PF06012--DUF908
PF06025--DUF913
PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

KEGG

act:ACLA_049950

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000627	Aegilops tauschii	32.37	4.00e-126	446.00
IUUC-Aml-001684	Ailuropoda melanoleuca	53.66	5.00e-134	472.00
IUUC-Atr-003044	Amborella trichopoda	42.14	2.00e-139	490.00
IUUC-Apl-003729	Anas platyrhynchos	52.11	9.00e-101	358.00
IUUC-Aca-005263	Anolis carolinensis	54.14	4.00e-135	476.00
IUUC-Aly-006157	Arabidopsis lyrata	41.35	1.00e-138	487.00
IUUC-Ath-007472	Arabidopsis thaliana	44.05	7.00e-135	474.00
IUUC-Ago-008005	Ashbya gossypii	57.68	0.00e+00	751.00
IUUC-Afl-008712	Aspergillus flavus	85.62	0.00e+00	1837.00
IUUC-Afu-009022	Aspergillus fumigatus	86.18	0.00e+00	6441.00
IUUC-Ani-009412	Aspergillus nidulans	69.90	0.00e+00	3653.00
IUUC-Ang-009771	Aspergillus niger	78.95	0.00e+00	5960.00
IUUC-Aor-010186	Aspergillus oryzae	83.18	0.00e+00	2127.00
IUUC-Ate-010253	Aspergillus terreus	74.48	0.00e+00	3482.00
IUUC-Ame-011067	Astyanax mexicanus	53.41	4.00e-133	469.00
IUUC-Bgr-012043	Blumeria graminis	39.39	0.00e+00	1483.00
IUUC-Bta-012813	Bos taurus	53.66	5.00e-134	472.00
IUUC-Bci-013995	Botrytis cinerea	38.70	0.00e+00	1483.00
IUUC-Bdi-014884	Brachypodium distachyon	35.14	4.00e-140	492.00
IUUC-Bol-016533	Brassica oleracea	55.64	2.00e-91	326.00
IUUC-Bra-016726	Brassica rapa	42.92	3.00e-139	489.00
IUUC-Cel-018179	Caenorhabditis elegans	51.76	3.00e-130	459.00
IUUC-Cja-018741	Callithrix jacchus	53.90	2.00e-133	470.00
IUUC-Cfa-020083	Canis familiaris	53.66	7.00e-134	472.00
IUUC-Cpo-021923	Cavia porcellus	43.91	2.00e-95	344.00
IUUC-Cre-022900	Chlamydomonas reinhardtii	52.01	1.00e-132	464.00
IUUC-Csa-023853	Chlorocebus sabaeus	53.66	6.00e-134	472.00
IUUC-Cho-024718	Choloepus hoffmanni	56.55	1.00e-122	434.00
IUUC-Cin-025627	Ciona intestinalis	52.48	2.00e-131	464.00
IUUC-Csv-025872	Ciona savignyi	52.25	4.00e-128	449.00
IUUC-Cgl-026647	Colletotrichum gloeosporioides	58.28	0.00e+00	1204.00
IUUC-Cne-027095	Cryptococcus neoformans	38.77	0.00e+00	676.00
IUUC-Cme-027267	Cyanidioschyzon merolae	51.31	1.00e-119	423.00
IUUC-Dre-028525	Danio rerio	52.44	9.00e-121	428.00
IUUC-Dno-029680	Dasypus novemcinctus	53.66	6.00e-134	472.00
IUUC-Dor-030902	Dipodomys ordii	48.46	2.00e-113	404.00
IUUC-Dse-031197	Dothistroma septosporum	36.09	0.00e+00	1310.00
IUUC-Dme-032122	Drosophila melanogaster	52.24	2.00e-128	454.00
IUUC-Ete-032966	Echinops telfairi	41.88	3.00e-96	344.00
IUUC-Eca-033915	Equus caballus	52.61	2.00e-131	464.00
IUUC-Eeu-034963	Erinaceus europaeus	53.30	7.00e-132	465.00
IUUC-Fca-035824	Felis catus	53.66	6.00e-134	472.00
IUUC-Fox-037756	Fusarium oxysporum	57.61	0.00e+00	1230.00
IUUC-Fso-038464	Fusarium solani	57.99	0.00e+00	1218.00
IUUC-Gmo-039073	Gadus morhua	53.43	3.00e-134	473.00
IUUC-Ggr-039946	Gaeumannomyces graminis	57.56	0.00e+00	1179.00
IUUC-Gga-040309	Gallus gallus	58.31	5.00e-106	375.00
IUUC-Gac-042430	Gasterosteus aculeatus	53.43	5.00e-134	472.00
IUUC-Gma-044216	Glycine max	33.99	7.00e-159	554.00
IUUC-Hsa-046879	Homo sapiens	53.66	5.00e-134	472.00
IUUC-Hvu-047697	Hordeum vulgare	41.38	1.00e-134	474.00
IUUC-Itr-048430	Ictidomys tridecemlineatus	53.66	3.00e-134	471.00
IUUC-Kpa-049228	Komagataella pastoris	60.06	0.00e+00	787.00
IUUC-Lch-050252	Latimeria chalumnae	53.54	3.00e-133	469.00
IUUC-Lpe-051550	Leersia perrieri	33.99	3.00e-148	519.00
IUUC-Loc-052472	Lepisosteus oculatus	53.90	5.00e-135	475.00
IUUC-Lma-053159	Leptosphaeria maculans	41.40	0.00e+00	1651.00
IUUC-Laf-054154	Loxodonta africana	53.66	5.00e-134	472.00
IUUC-Mcc-055085	Macaca mulatta	53.66	6.00e-134	472.00
IUUC-Mor-057201	Magnaporthe oryzae	56.92	0.00e+00	1168.00
IUUC-Mpo-057597	Magnaporthe poae	70.72	0.00e+00	958.00
IUUC-Mtr-057633	Medicago truncatula	33.56	2.00e-159	556.00
IUUC-Mla-058888	Melampsora laricipopulina	57.99	4.00e-143	499.00
IUUC-Mga-059935	Meleagris gallopavo	41.88	1.00e-95	342.00
IUUC-Mvi-060320	Microbotryum violaceum	44.58	0.00e+00	741.00
IUUC-Mmr-060820	Microcebus murinus	53.66	6.00e-134	472.00
IUUC-Mdo-062930	Monodelphis domestica	53.90	1.00e-134	474.00
IUUC-Mmu-063601	Mus musculus	53.66	5.00e-134	472.00
IUUC-Mac-065229	Musa acuminata	33.96	2.00e-153	536.00
IUUC-Mpu-066653	Mustela putorius furo	53.66	6.00e-134	472.00
IUUC-Mlu-067418	Myotis lucifugus	53.66	4.00e-134	473.00
IUUC-Nfi-068278	Neosartorya fischeri	87.05	0.00e+00	6420.00
IUUC-Ncr-068813	Neurospora crassa	34.66	0.00e+00	1152.00
IUUC-Nle-069418	Nomascus leucogenys	53.66	7.00e-134	471.00
IUUC-Ont-071300	Oreochromis niloticus	53.43	5.00e-134	472.00
IUUC-Oan-073046	Ornithorhynchus anatinus	53.88	7.00e-134	471.00
IUUC-Ocu-074178	Oryctolagus cuniculus	53.66	2.00e-134	473.00
IUUC-Oba-075757	Oryza barthii	33.42	1.00e-150	527.00
IUUC-Obr-076553	Oryza brachyantha	33.69	2.00e-150	526.00
IUUC-Ogl-077520	Oryza glaberrima	33.42	7.00e-151	528.00
IUUC-Ogu-078278	Oryza glumaepatula	33.14	6.00e-147	514.00
IUUC-Oin-079767	Oryza indica	33.42	8.00e-151	528.00
IUUC-Olo-080380	Oryza longistaminata	33.03	5.00e-145	508.00
IUUC-Ome-081925	Oryza meridionalis	33.17	1.00e-148	520.00
IUUC-Oni-082619	Oryza nivara	33.93	9.00e-151	528.00
IUUC-Opu-083684	Oryza punctata	33.39	6.00e-147	514.00
IUUC-Oru-084501	Oryza rufipogon	33.42	6.00e-151	528.00
IUUC-Osa-086251	Oryza sativa	40.26	2.00e-138	484.00
IUUC-Olu-087813	Ostreococcus lucimarinus	47.91	2.00e-114	404.00
IUUC-Oga-088903	Otolemur garnettii	53.66	5.00e-134	472.00
IUUC-Oar-090210	Ovis aries	53.66	6.00e-134	472.00
IUUC-Pan-092368	Papio anubis	52.96	4.00e-121	429.00
IUUC-Pno-094871	Phaeosphaeria nodorum	61.29	0.00e+00	1262.00
IUUC-Ppa-095657	Physcomitrella patens	51.16	2.00e-130	460.00
IUUC-Pfo-096232	Poecilia formosa	53.43	3.00e-134	473.00
IUUC-Pab-098583	Pongo abelii	53.66	6.00e-134	472.00
IUUC-Pop-099468	Populus trichocarpa	33.09	4.00e-156	545.00
IUUC-Ppe-101641	Prunus persica	45.51	2.00e-137	483.00
IUUC-Pva-102116	Pteropus vampyrus	50.35	4.00e-120	426.00
IUUC-Pgr-103465	Puccinia graminis	49.17	0.00e+00	635.00
IUUC-Ptt-103813	Puccinia triticina	41.81	0.00e+00	755.00
IUUC-Pte-104018	Pyrenophora teres	42.14	0.00e+00	1737.00
IUUC-Pyt-104713	Pyrenophora triticirepentis	61.71	0.00e+00	1302.00
IUUC-Sce-106449	Saccharomyces cerevisiae	55.62	0.00e+00	735.00
IUUC-Sha-106961	Sarcophilus harrisii	53.90	1.00e-134	474.00
IUUC-Sja-107814	Schizosaccharomyces japonicus	45.50	0.00e+00	902.00
IUUC-Spo-108024	Schizosaccharomyces pombe	44.41	0.00e+00	849.00
IUUC-Smo-109640	Selaginella moellendorffii	47.01	7.00e-134	471.00
IUUC-Sit-110598	Setaria italica	33.66	4.00e-150	525.00
IUUC-Sly-111706	Solanum lycopersicum	41.51	3.00e-139	489.00
IUUC-Stu-112894	Solanum tuberosum	33.59	2.00e-55	209.00
IUUC-Sar-113291	Sorex araneus	53.61	2.00e-129	457.00
IUUC-Sbi-114042	Sorghum bicolor	34.39	5.00e-151	528.00
IUUC-Sre-114958	Sporisorium reilianum	58.74	4.00e-175	605.00
IUUC-Ssc-115754	Sus scrofa	53.66	6.00e-134	472.00
IUUC-Tru-118570	Takifugu rubripes	53.43	3.00e-134	473.00
IUUC-Tni-120836	Tetraodon nigroviridis	51.77	2.00e-128	453.00
IUUC-Tca-121479	Theobroma cacao	45.25	9.00e-138	484.00
IUUC-Tre-121909	Trichoderma reesei	57.51	0.00e+00	1187.00
IUUC-Tvi-122370	Trichoderma virens	57.17	0.00e+00	1187.00
IUUC-Tae-125214	Triticum aestivum	32.96	2.00e-145	509.00
IUUC-Tme-127172	Tuber melanosporum	72.99	0.00e+00	986.00
IUUC-Ttr-129253	Tursiops truncatus	53.66	8.00e-134	471.00
IUUC-Uma-129355	Ustilago maydis	59.33	9.00e-179	618.00
IUUC-Vda-129886	Verticillium dahliae	34.39	0.00e+00	1179.00
IUUC-Vpa-130708	Vicugna pacos	53.66	1.00e-133	471.00
IUUC-Vvi-131078	Vitis vinifera	45.56	8.00e-138	484.00
IUUC-Xtr-132123	Xenopus tropicalis	51.54	3.00e-127	449.00
IUUC-Xma-133869	Xiphophorus maculatus	53.43	2.00e-134	473.00
IUUC-Yli-134657	Yarrowia lipolytica	47.93	0.00e+00	973.00
IUUC-Zma-135570	Zea mays	34.52	1.00e-151	531.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence