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Tag Content
UUCD2 ID IUUC-Xtr-132512
UUCD1 version UUC-XeT-00025
Ensembl Protein ID ENSXETP00000057130.2
UniProt Accession Q28DS3; RN170_XENTR
Genbank Protein ID CAJ83943.1
Protein Name E3 ubiquitin-protein ligase RNF170; RING finger protein 170; RING-type E3 ubiquitin transferase RNF170
Genbank Nucleotide ID CR848624
Gene Name rnf170; TGas116k14.1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSXETG00000027376.2 ENSXETT00000057130.2 ENSXETP00000057130.2
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/RING/RING 34.01 8.00e-20 94.00 IUUC-Cel-018593
E3 activity/RING/RING 70.77 8.00e-92 334.00 IUUC-Hsa-046691
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Xenopus tropicalis
Functional Description
(View)

Functional Description


     E3 ubiquitin-protein ligase that plays an essential role in stimulus-induced inositol 1,4,5-trisphosphate receptor (ITPR) ubiquitination and degradation via the endoplasmic reticulum-associated degradation (ERAD) pathway. Also involved in ITPR turnover in resting cells.
 E3 ubiquitin-protein ligase that plays an essential role in stimulus-induced inositol 1,4,5-trisphosphate receptor (ITPR) ubiquitination and degradation via the endoplasmic reticulum-associated degradation (ERAD) pathway. Also involved in ITPR turnover in resting cells.
Protein Sequence
(Fasta)
MADNQEGRPY FPLDEGSIIE GVSDQVIVVV LLSFVAVGSL LYLLLRNDEQ NIHPENQDRV 60
RAVREQLQNE QETPPPPRPQ FYSDMTCPVC LQQATFPVET NCGHLFCGSC IIAYWRYGSW 120
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Protein Fasta Sequence


>IUUC-Xtr-132512|E3,RING|Xenopus tropicalis
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Nucleotide Sequence
(Fasta)
AAGCTGGGAC CTGTCAGGAA AAAGTAAGGG GAGATTGTAT AGCTGAGAGG CAGGCAGGAC 60
CTGTCAGCAC AAAGTAAGAG GAGATCGCAT AAATGTTACT AGCAGTACGG TACCTATAAT 120
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Nucleotide Fasta Sequence


>IUUC-Xtr-132512|E3,RING|Xenopus tropicalis
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Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0256--Endoplasmic reticulum
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR010652--DUF1232
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2
Pfam

PF06803--DUF1232
PF00097--zf-C3HC4
SMART

SM00184--RING
Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0016021--C:integral component of membrane
GO:0016740--F:transferase activity
GO:0008270--F:zinc ion binding
GO:0016567--P:protein ubiquitination
KEGG xtr:549626
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000837 Aegilops tauschii 36.42 9.00e-23 99.40
IUUC-Aml-002276 Ailuropoda melanoleuca 70.16 2.00e-89 321.00
IUUC-Atr-003163 Amborella trichopoda 37.63 7.00e-29 119.00
IUUC-Apl-003771 Anas platyrhynchos 68.48 2.00e-87 314.00
IUUC-Aca-004706 Anolis carolinensis 69.26 2.00e-84 305.00
IUUC-Aly-006202 Arabidopsis lyrata 39.62 1.00e-19 89.00
IUUC-Ath-007325 Arabidopsis thaliana 37.06 7.00e-27 112.00
IUUC-Ame-011453 Astyanax mexicanus 72.80 6.00e-97 346.00
IUUC-Bta-013272 Bos taurus 69.11 1.00e-87 315.00
IUUC-Bdi-014259 Brachypodium distachyon 38.38 1.00e-26 112.00
IUUC-Bol-016302 Brassica oleracea 37.65 1.00e-26 112.00
IUUC-Bra-017738 Brassica rapa 37.65 3.00e-26 110.00
IUUC-Cel-018593 Caenorhabditis elegans 33.52 2.00e-26 112.00
IUUC-Cja-019253 Callithrix jacchus 70.38 2.00e-88 318.00
IUUC-Cfa-020844 Canis familiaris 71.09 2.00e-88 320.00
IUUC-Cpo-021645 Cavia porcellus 70.77 7.00e-90 323.00
IUUC-Csa-024012 Chlorocebus sabaeus 70.38 3.00e-89 321.00
IUUC-Cho-024304 Choloepus hoffmanni 54.23 2.00e-58 218.00
IUUC-Cin-025256 Ciona intestinalis 48.47 2.00e-56 212.00
IUUC-Dre-028166 Danio rerio 70.00 8.00e-82 296.00
IUUC-Dno-029494 Dasypus novemcinctus 70.16 1.00e-89 322.00
IUUC-Dor-030259 Dipodomys ordii 69.62 3.00e-86 311.00
IUUC-Ete-032614 Echinops telfairi 61.63 2.00e-68 251.00
IUUC-Eca-033557 Equus caballus 70.93 4.00e-90 323.00
IUUC-Eeu-035324 Erinaceus europaeus 85.39 4.00e-27 115.00
IUUC-Fca-035812 Felis catus 70.54 7.00e-90 323.00
IUUC-Fal-036654 Ficedula albicollis 71.98 2.00e-95 342.00
IUUC-Gmo-039635 Gadus morhua 67.67 7.00e-88 316.00
IUUC-Ggr-039833 Gaeumannomyces graminis 42.31 2.00e-07 50.10
IUUC-Gga-040345 Gallus gallus 71.60 2.00e-95 341.00
IUUC-Gac-041668 Gasterosteus aculeatus 66.92 8.00e-90 322.00
IUUC-Gma-043890 Glycine max 32.56 2.00e-26 111.00
IUUC-Ggo-045000 Gorilla gorilla 70.38 3.00e-89 321.00
IUUC-Hsa-046691 Homo sapiens 70.77 2.00e-89 322.00
IUUC-Hvu-047464 Hordeum vulgare 38.64 8.00e-27 113.00
IUUC-Itr-048988 Ictidomys tridecemlineatus 70.00 9.00e-89 319.00
IUUC-Lch-049846 Latimeria chalumnae 82.58 1.00e-63 235.00
IUUC-Loc-051785 Lepisosteus oculatus 70.92 2.00e-104 371.00
IUUC-Laf-054542 Loxodonta africana 70.20 2.00e-84 305.00
IUUC-Mcc-055234 Macaca mulatta 70.38 3.00e-89 321.00
IUUC-Meu-056544 Macropus eugenii 57.75 3.00e-61 228.00
IUUC-Mor-057034 Magnaporthe oryzae 38.46 2.00e-07 50.10
IUUC-Mpo-057316 Magnaporthe poae 39.29 8.00e-07 48.10
IUUC-Mtr-057996 Medicago truncatula 34.10 4.00e-15 74.30
IUUC-Mmr-060609 Microcebus murinus 68.99 8.00e-93 332.00
IUUC-Mdo-062853 Monodelphis domestica 72.09 2.00e-95 341.00
IUUC-Mmu-064383 Mus musculus 72.36 3.00e-84 304.00
IUUC-Mac-065250 Musa acuminata 37.70 5.00e-28 117.00
IUUC-Mlu-067410 Myotis lucifugus 70.54 2.00e-90 325.00
IUUC-Nle-069537 Nomascus leucogenys 78.41 6.00e-66 242.00
IUUC-Opr-070637 Ochotona princeps 77.33 5.00e-51 194.00
IUUC-Ont-071800 Oreochromis niloticus 68.05 2.00e-87 315.00
IUUC-Oan-073190 Ornithorhynchus anatinus 70.16 8.00e-94 336.00
IUUC-Ocu-073899 Oryctolagus cuniculus 70.54 3.00e-89 320.00
IUUC-Obr-076075 Oryza brachyantha 40.15 1.00e-25 108.00
IUUC-Oin-079850 Oryza indica 38.73 5.00e-26 110.00
IUUC-Ome-081191 Oryza meridionalis 38.03 4.00e-25 107.00
IUUC-Oni-082886 Oryza nivara 38.73 4.00e-26 110.00
IUUC-Osa-085833 Oryza sativa 38.73 5.00e-26 110.00
IUUC-Ola-086372 Oryzias latipes 69.92 8.00e-91 326.00
IUUC-Oga-087988 Otolemur garnettii 70.54 1.00e-87 315.00
IUUC-Oar-089976 Ovis aries 69.50 5.00e-87 313.00
IUUC-Ptr-091377 Pan troglodytes 70.00 4.00e-89 320.00
IUUC-Pan-092348 Papio anubis 70.38 4.00e-89 320.00
IUUC-Psi-092982 Pelodiscus sinensis 71.21 1.00e-91 328.00
IUUC-Ppa-095627 Physcomitrella patens 38.46 8.00e-23 100.00
IUUC-Pfo-096366 Poecilia formosa 68.05 2.00e-89 322.00
IUUC-Pab-098242 Pongo abelii 75.35 4.00e-82 296.00
IUUC-Pop-099776 Populus trichocarpa 35.26 1.00e-22 99.40
IUUC-Pca-100637 Procavia capensis 85.39 8.00e-27 113.00
IUUC-Ppe-101586 Prunus persica 37.88 1.00e-16 78.60
IUUC-Pva-102627 Pteropus vampyrus 70.54 2.00e-94 338.00
IUUC-Rno-105344 Rattus norvegicus 73.58 3.00e-87 314.00
IUUC-Sha-107420 Sarcophilus harrisii 70.27 5.00e-93 333.00
IUUC-Smo-109218 Selaginella moellendorffii 34.88 2.00e-27 114.00
IUUC-Sly-111612 Solanum lycopersicum 33.77 5.00e-20 91.30
IUUC-Stu-112127 Solanum tuberosum 34.68 9.00e-22 96.30
IUUC-Sar-113762 Sorex araneus 70.38 1.00e-89 322.00
IUUC-Sbi-113997 Sorghum bicolor 38.29 4.00e-26 110.00
IUUC-Ssc-115764 Sus scrofa 86.36 8.00e-27 110.00
IUUC-Tgu-116969 Taeniopygia guttata 71.98 4.00e-96 343.00
IUUC-Tru-118414 Takifugu rubripes 69.06 2.00e-82 298.00
IUUC-Tsy-119312 Tarsius syrichta 64.62 6.00e-81 293.00
IUUC-Tni-120687 Tetraodon nigroviridis 74.38 8.00e-89 319.00
IUUC-Tca-121028 Theobroma cacao 36.05 6.00e-19 86.70
IUUC-Tae-122873 Triticum aestivum 38.89 2.00e-26 111.00
IUUC-Tur-126558 Triticum urartu 38.41 7.00e-20 89.70
IUUC-Tbe-127751 Tupaia belangeri 61.24 2.00e-67 248.00
IUUC-Ttr-128731 Tursiops truncatus 66.67 2.00e-84 305.00
IUUC-Vpa-130187 Vicugna pacos 68.85 1.00e-87 315.00
IUUC-Vvi-131393 Vitis vinifera 37.23 2.00e-25 108.00
IUUC-Xma-133203 Xiphophorus maculatus 69.14 2.00e-88 318.00
Created Date 25-Jun-2017

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