iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssc-115820

Ensembl Protein ID

ENSSSCP00000027116.1

UniProt Accession

I3LSM3; I3LSM3_PIG

Genbank Protein ID

ENSSSCP00000027116

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

FP476077

Gene Name

UBQLN1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000021005.1	ENSSSCT00000027988.1	ENSSSCP00000027116.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	5.30e-10	39.4	547	584
ULD/UDP/UBQ/UBQ_PIM	5.40e-25	87.4	37	110

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGF.dreealqaLraannnleaAveyLl 39
           ++++leql +MGF +re++lqaL a++++++aA+e+Ll
   Q: 547  FQQQLEQLSAMGFlNREANLQALIATGGDINAAIERLL 584
           799**********************************9 PP

ULD/UDP/UBQ/UBQ_PIM

   S: 1    mkltvktlkgkefelevseddtveelKekiakesgvppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvkksk 75
           mk+tvkt+k+ke e+ v e+++v+++Ke+i+k+++ + +q+ LI+aGkiLkD++tLs++gi+dg +vhlv+k+++
   Q: 37   MKVTVKTPKEKE-EFAVPENSSVQQFKEEISKRFKSHTDQLVLIFAGKILKDQDTLSQHGIHDGLTVHLVIKTQN 110
           99**********.***********************************************************987 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

WAENGESGSP PSSQDSAAAA EGAGAPAAAA SAEPKIMKVT VKTPKEKEEF AVPENSSVQQ 60
FKEEISKRFK SHTDQLVLIF AGKILKDQDT LSQHGIHDGL TVHLVIKTQN RPQDHSAQQT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGGGCCGAGA ATGGTGAAAG CGGCAGCCCT CCGAGCTCCC AGGACAGCGC CGCCGCGGCC 60
GAAGGTGCCG GCGCCCCCGC GGCCGCTGCC TCCGCCGAGC CCAAGATCAT GAAAGTCACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR006636--STI1_HS-bd
IPR015940--UBA
IPR009060--UBA-like
IPR015496--Ubiquilin
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50030--UBA
PS50053--UBIQUITIN_2

Pfam

PF00627--UBA
PF00240--ubiquitin

SMART

SM00727--STI1
SM00165--UBA
SM00213--UBQ

Gene Ontology

GO:0016235--C:aggresome
GO:0005776--C:autophagosome
GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0005654--C:nucleoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0005886--C:plasma membrane
GO:0043234--C:protein complex
GO:0035973--P:aggrephagy
GO:0000045--P:autophagosome assembly
GO:0097352--P:autophagosome maturation
GO:0071456--P:cellular response to hypoxia
GO:1901340--P:negative regulation of store-operated calcium channel activity
GO:0034140--P:negative regulation of toll-like receptor 3 signaling pathway
GO:1903071--P:positive regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:0031398--P:positive regulation of protein ubiquitination
GO:1902175--P:regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000864	Aegilops tauschii	49.65	8.00e-38	151.00
IUUC-Aml-001461	Ailuropoda melanoleuca	97.77	0.00e+00	809.00
IUUC-Atr-002470	Amborella trichopoda	40.29	6.00e-44	171.00
IUUC-Apl-003241	Anas platyrhynchos	84.14	0.00e+00	719.00
IUUC-Aca-004511	Anolis carolinensis	81.17	0.00e+00	720.00
IUUC-Aly-005419	Arabidopsis lyrata	37.20	5.00e-49	188.00
IUUC-Ath-007350	Arabidopsis thaliana	36.84	2.00e-49	189.00
IUUC-Ago-007963	Ashbya gossypii	37.68	9.00e-09	53.90
IUUC-Bta-013048	Bos taurus	96.76	0.00e+00	828.00
IUUC-Bdi-014506	Brachypodium distachyon	35.94	1.00e-49	191.00
IUUC-Bol-015326	Brassica oleracea	35.48	5.00e-42	165.00
IUUC-Bra-018014	Brassica rapa	38.06	2.00e-42	166.00
IUUC-Cel-018631	Caenorhabditis elegans	37.99	2.00e-66	246.00
IUUC-Cja-019976	Callithrix jacchus	96.94	0.00e+00	832.00
IUUC-Cfa-020092	Canis familiaris	97.84	0.00e+00	840.00
IUUC-Cpo-022388	Cavia porcellus	94.59	0.00e+00	815.00
IUUC-Csa-024087	Chlorocebus sabaeus	96.72	0.00e+00	834.00
IUUC-Cho-024834	Choloepus hoffmanni	96.53	0.00e+00	844.00
IUUC-Cin-025136	Ciona intestinalis	50.55	4.00e-113	401.00
IUUC-Csv-026009	Ciona savignyi	57.33	8.00e-78	284.00
IUUC-Cne-026833	Cryptococcus neoformans	26.34	2.00e-12	66.20
IUUC-Cme-027155	Cyanidioschyzon merolae	58.10	1.00e-34	140.00
IUUC-Dno-028970	Dasypus novemcinctus	77.48	0.00e+00	658.00
IUUC-Dor-030519	Dipodomys ordii	92.45	0.00e+00	796.00
IUUC-Dse-031421	Dothistroma septosporum	28.10	3.00e-10	59.70
IUUC-Dme-032013	Drosophila melanogaster	46.20	6.00e-111	394.00
IUUC-Ete-032273	Echinops telfairi	95.09	0.00e+00	810.00
IUUC-Eca-033667	Equus caballus	96.26	0.00e+00	836.00
IUUC-Eeu-034727	Erinaceus europaeus	76.75	5.00e-157	547.00
IUUC-Fca-036179	Felis catus	94.42	0.00e+00	791.00
IUUC-Fal-037642	Ficedula albicollis	83.54	0.00e+00	765.00
IUUC-Gga-041264	Gallus gallus	84.77	0.00e+00	807.00
IUUC-Gma-042681	Glycine max	36.52	1.00e-37	150.00
IUUC-Ggo-044969	Gorilla gorilla	96.58	0.00e+00	814.00
IUUC-Hsa-046669	Homo sapiens	96.76	0.00e+00	847.00
IUUC-Itr-048337	Ictidomys tridecemlineatus	95.31	0.00e+00	679.00
IUUC-Lch-050192	Latimeria chalumnae	76.24	0.00e+00	678.00
IUUC-Lpe-051401	Leersia perrieri	38.82	4.00e-36	145.00
IUUC-Loc-052846	Lepisosteus oculatus	77.80	0.00e+00	670.00
IUUC-Lma-053152	Leptosphaeria maculans	30.04	9.00e-12	64.70
IUUC-Laf-054278	Loxodonta africana	95.50	0.00e+00	794.00
IUUC-Mcc-055680	Macaca mulatta	97.12	0.00e+00	847.00
IUUC-Meu-056414	Macropus eugenii	79.90	3.00e-157	548.00
IUUC-Mtr-058674	Medicago truncatula	37.63	9.00e-40	157.00
IUUC-Mga-059894	Meleagris gallopavo	83.68	0.00e+00	639.00
IUUC-Mmr-061094	Microcebus murinus	96.94	0.00e+00	822.00
IUUC-Mdo-062728	Monodelphis domestica	89.01	0.00e+00	767.00
IUUC-Mmu-064088	Mus musculus	84.77	0.00e+00	814.00
IUUC-Mac-065458	Musa acuminata	35.55	3.00e-43	169.00
IUUC-Mpu-066282	Mustela putorius furo	93.35	0.00e+00	804.00
IUUC-Mlu-068158	Myotis lucifugus	95.50	0.00e+00	801.00
IUUC-Nle-069321	Nomascus leucogenys	96.58	0.00e+00	847.00
IUUC-Opr-071098	Ochotona princeps	88.51	7.00e-179	619.00
IUUC-Oan-072808	Ornithorhynchus anatinus	87.57	0.00e+00	744.00
IUUC-Ocu-074301	Oryctolagus cuniculus	87.77	0.00e+00	780.00
IUUC-Oba-074973	Oryza barthii	38.39	8.00e-43	167.00
IUUC-Obr-076444	Oryza brachyantha	50.34	2.00e-32	134.00
IUUC-Ogl-077319	Oryza glaberrima	38.39	2.00e-43	169.00
IUUC-Oin-079142	Oryza indica	37.86	2.00e-43	170.00
IUUC-Olo-080565	Oryza longistaminata	38.19	7.00e-43	167.00
IUUC-Ome-081155	Oryza meridionalis	45.19	3.00e-34	139.00
IUUC-Oni-082272	Oryza nivara	37.86	2.00e-43	170.00
IUUC-Opu-083241	Oryza punctata	35.02	9.00e-50	191.00
IUUC-Oru-085257	Oryza rufipogon	37.86	2.00e-43	170.00
IUUC-Osa-086257	Oryza sativa	38.39	2.00e-43	169.00
IUUC-Olu-087597	Ostreococcus lucimarinus	32.48	2.00e-25	109.00
IUUC-Oga-088495	Otolemur garnettii	95.68	0.00e+00	798.00
IUUC-Oar-089711	Ovis aries	95.92	0.00e+00	801.00
IUUC-Ptr-091439	Pan troglodytes	96.40	0.00e+00	841.00
IUUC-Pan-092641	Papio anubis	97.12	0.00e+00	847.00
IUUC-Psi-093518	Pelodiscus sinensis	83.90	0.00e+00	717.00
IUUC-Pma-094727	Petromyzon marinus	41.08	5.00e-52	198.00
IUUC-Ppa-095193	Physcomitrella patens	52.80	2.00e-35	143.00
IUUC-Pfo-096638	Poecilia formosa	68.11	8.00e-171	593.00
IUUC-Pab-098699	Pongo abelii	94.41	0.00e+00	838.00
IUUC-Pop-099549	Populus trichocarpa	40.54	2.00e-47	183.00
IUUC-Pca-100497	Procavia capensis	83.52	1.00e-134	472.00
IUUC-Ppe-101901	Prunus persica	35.62	6.00e-57	214.00
IUUC-Pva-102513	Pteropus vampyrus	84.77	2.00e-147	515.00
IUUC-Pgr-103261	Puccinia graminis	54.76	2.00e-07	49.70
IUUC-Rno-104908	Rattus norvegicus	85.28	0.00e+00	836.00
IUUC-Sha-106881	Sarcophilus harrisii	84.33	0.00e+00	698.00
IUUC-Spo-108223	Schizosaccharomyces pombe	27.65	1.00e-10	60.10
IUUC-Smo-109502	Selaginella moellendorffii	35.81	4.00e-38	152.00
IUUC-Sit-110766	Setaria italica	40.00	2.00e-36	146.00
IUUC-Sar-113648	Sorex araneus	88.31	0.00e+00	633.00
IUUC-Sbi-114307	Sorghum bicolor	36.60	3.00e-44	172.00
IUUC-Tgu-116845	Taeniopygia guttata	79.14	0.00e+00	681.00
IUUC-Tsy-119008	Tarsius syrichta	76.61	9.00e-152	530.00
IUUC-Tni-119780	Tetraodon nigroviridis	66.13	3.00e-170	591.00
IUUC-Tca-121558	Theobroma cacao	35.75	3.00e-53	202.00
IUUC-Tae-125518	Triticum aestivum	49.65	2.00e-38	153.00
IUUC-Tur-126248	Triticum urartu	49.65	3.00e-38	153.00
IUUC-Tbe-127379	Tupaia belangeri	82.83	0.00e+00	668.00
IUUC-Ttr-128630	Tursiops truncatus	95.94	0.00e+00	842.00
IUUC-Vpa-130413	Vicugna pacos	72.30	4.00e-160	557.00
IUUC-Vvi-131599	Vitis vinifera	39.46	7.00e-42	164.00
IUUC-Xtr-132595	Xenopus tropicalis	80.43	0.00e+00	701.00
IUUC-Xma-134155	Xiphophorus maculatus	64.61	4.00e-167	581.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence