iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssc-115271

Ensembl Protein ID

ENSSSCP00000015737.2

UniProt Accession

F1SUV0; F1SUV0_PIG

Genbank Protein ID

ENSSSCP00000015737

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

CU694608

Gene Name

ATG16L2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000014819.2	ENSSSCT00000016170.2	ENSSSCP00000015737.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.30e-26	91.0	556	586
UBD/Beta-Prp	1.60e-44	152.5	335	620

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 8    claf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           ++ f +d  + ++Gs+Dg +++WD++tg+l+ 
   Q: 556  AV-FsPDrSYALAGSWDGALYIWDVDTGKLES 586
           33.599999*******************9875 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgh 93
           ++h s +++v+f p++s+latg++d+ i +w+v  g l   ++l+g  + +t+v+f+p+g+  + +   +++++w +   +   tl+gh
   Q: 335  EAHLSEVNAVHFGPNSSVLATGGADRLILLWNVVGGRLkaKQTLEGAGGSITSVDFDPSGSQVLAATYNKAAQLWKVGEAQSKETLSGH 423
           6788999*****************************9988999******************99999*********************** PP
   S: 94   edsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtds 182
           +d+v++ +f  +++  v+Gs+drt++ wdl   +c++ t s+ +  + +v+ +    +++sG++D+++r+Wd++  ++ +      +++
   Q: 424  TDKVTAAKFKLTRHQAVTGSRDRTVKEWDLGRAYCSR-TISVVSYCNDVVCGD---HIIISGHNDQKIRFWDSRGPRCTQVIP--VQGR 506
           ************************************9.777777555555555...5*************************5..589* PP
   S: 183  vyslsfdsngkelvsgsldgtvklwdlqtgec.....vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnss 266
           v+sls+++++ +l+s+s+d t+k+ dl+ +++      + +++ +d++k   fsp+  + + gs Dg ++iWd+++g+l ++l +++  
   Q: 507  VTSLSLSHDQLHLLSCSRDDTLKVIDLRVSNIrqvfrADGFKCGSDWTK-AVFSPDRSYALAGSWDGALYIWDVDTGKLESSLRGPHCA 594
           ****************************888833334444555556666.8899*********************************77 PP
   S: 267  visvavlsfgdnvlvlgsedskvniw 292
            +   ++++++++++++++  k+ +w
   Q: 595  AVNAVAWCYSGSHVASVDQARKLVLW 620
           7777778*********9998888888 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MAGPSDPGAP VACWKRHIVR QLRLRDRTQK ALFLELVPAY NRLLEKAELL ARFSETLPPE 60
PNSVTPATHQ GPWEEEEAGP DSDQVPSPAA LRVKWQEEEE GLRLECGEMA YQVVVKSAAL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCCCCGCCC GGCCGCGCCC ACCTCTGCGA GAGCAGCGCG CGGGGCGGGC GGCAGCGGGC 60
GGCCATGGCG GGGCCCAGCG ACCCCGGCGC CCCTGTCGCC TGCTGGAAAC GCCACATCGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR013923--Autophagy-rel_prot_16
IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08614--ATG16
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0000421--C:autophagosome membrane
GO:0005654--C:nucleoplasm
GO:0000045--P:autophagosome assembly
GO:0039689--P:negative stranded viral RNA replication

KEGG

ssc:100511396

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001470	Ailuropoda melanoleuca	69.98	0.00e+00	773.00
IUUC-Atr-003073	Amborella trichopoda	32.09	3.00e-27	116.00
IUUC-Aca-004664	Anolis carolinensis	72.17	1.00e-100	358.00
IUUC-Ame-011152	Astyanax mexicanus	42.15	2.00e-116	412.00
IUUC-Bta-013118	Bos taurus	87.44	0.00e+00	972.00
IUUC-Cja-020002	Callithrix jacchus	85.21	0.00e+00	947.00
IUUC-Cfa-020878	Canis familiaris	84.43	0.00e+00	946.00
IUUC-Cpo-022476	Cavia porcellus	81.39	0.00e+00	885.00
IUUC-Csa-024134	Chlorocebus sabaeus	85.55	0.00e+00	944.00
IUUC-Cho-024853	Choloepus hoffmanni	69.46	1.00e-173	602.00
IUUC-Dre-027949	Danio rerio	41.33	6.00e-128	451.00
IUUC-Dno-029683	Dasypus novemcinctus	85.82	0.00e+00	781.00
IUUC-Dor-030897	Dipodomys ordii	78.23	0.00e+00	929.00
IUUC-Ete-032957	Echinops telfairi	94.02	9.00e-133	466.00
IUUC-Eca-033303	Equus caballus	91.98	1.00e-168	584.00
IUUC-Eeu-035336	Erinaceus europaeus	73.45	5.00e-151	527.00
IUUC-Fca-036232	Felis catus	86.63	0.00e+00	1024.00
IUUC-Gmo-038880	Gadus morhua	50.70	4.00e-70	258.00
IUUC-Gma-043452	Glycine max	28.06	1.00e-45	177.00
IUUC-Ggo-045130	Gorilla gorilla	89.33	0.00e+00	682.00
IUUC-Hsa-046359	Homo sapiens	87.50	0.00e+00	924.00
IUUC-Hvu-047655	Hordeum vulgare	28.17	8.00e-23	101.00
IUUC-Itr-048780	Ictidomys tridecemlineatus	83.82	0.00e+00	944.00
IUUC-Lch-050669	Latimeria chalumnae	54.82	5.00e-98	350.00
IUUC-Loc-052789	Lepisosteus oculatus	42.54	4.00e-115	408.00
IUUC-Laf-053699	Loxodonta africana	84.62	0.00e+00	936.00
IUUC-Mcc-055657	Macaca mulatta	81.00	0.00e+00	850.00
IUUC-Meu-056639	Macropus eugenii	49.80	9.00e-110	390.00
IUUC-Mmr-061314	Microcebus murinus	79.61	0.00e+00	845.00
IUUC-Mdo-061841	Monodelphis domestica	66.40	0.00e+00	707.00
IUUC-Mmu-064065	Mus musculus	81.09	0.00e+00	938.00
IUUC-Mac-065022	Musa acuminata	32.08	1.00e-39	156.00
IUUC-Mpu-066742	Mustela putorius furo	85.32	0.00e+00	934.00
IUUC-Mlu-067019	Myotis lucifugus	85.22	0.00e+00	815.00
IUUC-Nle-069037	Nomascus leucogenys	87.66	0.00e+00	972.00
IUUC-Opr-071039	Ochotona princeps	79.55	0.00e+00	874.00
IUUC-Oan-073431	Ornithorhynchus anatinus	73.46	1.00e-140	492.00
IUUC-Ocu-074772	Oryctolagus cuniculus	84.30	0.00e+00	832.00
IUUC-Ola-086964	Oryzias latipes	52.61	2.00e-83	301.00
IUUC-Oga-088188	Otolemur garnettii	84.19	0.00e+00	876.00
IUUC-Oar-090231	Ovis aries	81.72	0.00e+00	950.00
IUUC-Ptr-091434	Pan troglodytes	84.59	0.00e+00	879.00
IUUC-Pan-091868	Papio anubis	86.15	0.00e+00	937.00
IUUC-Psi-093652	Pelodiscus sinensis	64.73	2.00e-165	575.00
IUUC-Ppa-095699	Physcomitrella patens	30.77	4.00e-38	152.00
IUUC-Pfo-096960	Poecilia formosa	41.68	4.00e-100	358.00
IUUC-Pab-097776	Pongo abelii	86.51	0.00e+00	874.00
IUUC-Pca-100220	Procavia capensis	65.22	2.00e-179	621.00
IUUC-Ppe-101790	Prunus persica	28.54	4.00e-43	169.00
IUUC-Pva-103135	Pteropus vampyrus	88.28	0.00e+00	896.00
IUUC-Rno-105529	Rattus norvegicus	79.97	0.00e+00	967.00
IUUC-Sha-107062	Sarcophilus harrisii	65.71	0.00e+00	744.00
IUUC-Sar-113109	Sorex araneus	67.00	1.00e-132	466.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence