iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cme-027267

Ensembl Protein ID

CMR077CT

UniProt Accession

M1VL32; M1VL32_CYAM1

Genbank Protein ID

BAM82348.1

Protein Name

Ubiquitin-protein ligase E3

Genbank Nucleotide ID

AP006500

Gene Name

CYME_CMR077C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CMR077C	CMR077CT	CMR077CT

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.10e-112	373.9	1395	1728

Active Site

Position(s)	Description	Evidence
1696	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfyklll 101
           ++l+  l v+fvgEeg+d+gG+ re++  l++++++ ++ lf++  ++++ +++n+ s++ n++hl +F+f+Gr++gkal dg+lld+ +++s+yk+++
   Q: 1395 AELRGTLTVQFVGEEGIDAGGLLREWYVILARKIFDENYALFRRCVGKSAAYHINECSYI-NEDHLGFFKFIGRFIGKALWDGQLLDAYFARSVYKHMI 1492
           678999*****************************************************9.66************************************ PP
   S: 102  gkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfnev 200
           g + s++d+e++dpe+y sl +++e+   +i    ldlt+ ++ +++ge k+++L+pgG++ipVt+eNk eYv+l++e+++++ ++ q++af eGf+e+
   Q: 1493 GIRPSYHDIEAIDPEYYASLVWMLEH---NIAHV-LDLTMAAELDQFGELKVVDLVPGGRHIPVTEENKWEYVRLITELKMTKAVEPQLQAFLEGFHEM 1587
           ************************99...99998.**************************************************************** PP
   S: 201  iplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelk.....prlfvirk.da 293
           +p +l+++F+  elelli+G +eid  dlk +t+y +gy ++sp+iqwFw+++ e+++++r++++ FvTgss++PlgGfa+l+      ++f+i++ ++
   Q: 1588 VPRSLIAMFSDYELELLISGLPEIDTADLKMHTTY-SGYRPSSPQIQWFWQAVAEMDRDDRARLVMFVTGSSKVPLGGFANLPgmnggVQRFQIHRvAG 1685
           ***********************************.55**************************************************999***99777 PP
   S: 294  sddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFel 335
           ++drlPs++TCfn+L+LPeYss+e+l+e+Ll+A++e+ +gF++
   Q: 1686 DTDRLPSAHTCFNQLDLPEYSSYEKLRERLLTAVREGnEGFGF 1728
           77***********************************9***85 PP

Organism

Cyanidioschyzon merolae

Protein Sequence
(Fasta)

MEDEHPAPNS DRTYASDLEQ GNVFGSSPSE RHSFSRLDGN RAGSIGDEMD SDVAVDEEDR 60
NAGMEVLGLF SVRARSRARV RSDNRDGSDS GSALDEGVDD NSDDHGDDIA GFGESDDLSG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGGACG AACATCCTGC GCCTAACTCG GATCGCACCT ATGCCAGCGA CTTGGAGCAG 60
GGGAACGTTT TCGGGAGCAG CCCCTCCGAG CGACACAGTT TCAGCCGCCT TGATGGCAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR025527--DUF4414
IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF14377--DUF4414
PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

KEGG

cme:CYME_CMR077C

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000627	Aegilops tauschii	47.88	1.00e-112	400.00
IUUC-Aml-001684	Ailuropoda melanoleuca	50.00	1.00e-122	434.00
IUUC-Atr-002582	Amborella trichopoda	52.82	1.00e-135	477.00
IUUC-Apl-003752	Anas platyrhynchos	43.57	6.00e-93	333.00
IUUC-Aca-005263	Anolis carolinensis	50.24	3.00e-123	436.00
IUUC-Aly-006157	Arabidopsis lyrata	54.50	1.00e-140	493.00
IUUC-Ath-007160	Arabidopsis thaliana	50.91	2.00e-132	466.00
IUUC-Ago-008005	Ashbya gossypii	44.00	2.00e-111	395.00
IUUC-Acl-008254	Aspergillus clavatus	45.95	7.00e-128	451.00
IUUC-Afl-008712	Aspergillus flavus	52.27	2.00e-129	454.00
IUUC-Afu-009022	Aspergillus fumigatus	51.07	7.00e-128	451.00
IUUC-Ani-009412	Aspergillus nidulans	50.00	1.00e-126	447.00
IUUC-Ang-009771	Aspergillus niger	50.47	1.00e-128	454.00
IUUC-Aor-010186	Aspergillus oryzae	51.03	2.00e-116	411.00
IUUC-Ate-010253	Aspergillus terreus	51.79	1.00e-128	454.00
IUUC-Ame-011067	Astyanax mexicanus	50.00	2.00e-121	430.00
IUUC-Bgr-012043	Blumeria graminis	49.66	1.00e-130	460.00
IUUC-Bta-012813	Bos taurus	50.00	8.00e-123	434.00
IUUC-Bci-013995	Botrytis cinerea	49.07	4.00e-129	455.00
IUUC-Bdi-014884	Brachypodium distachyon	53.29	3.00e-135	476.00
IUUC-Bol-016533	Brassica oleracea	59.06	8.00e-100	353.00
IUUC-Bra-016726	Brassica rapa	54.04	5.00e-139	488.00
IUUC-Cel-018179	Caenorhabditis elegans	46.24	1.00e-114	407.00
IUUC-Cja-018741	Callithrix jacchus	49.88	6.00e-122	431.00
IUUC-Cfa-020083	Canis familiaris	50.00	1.00e-122	434.00
IUUC-Cpo-021766	Cavia porcellus	41.90	8.00e-94	335.00
IUUC-Cre-022900	Chlamydomonas reinhardtii	53.19	8.00e-129	451.00
IUUC-Csa-023853	Chlorocebus sabaeus	50.00	9.00e-123	434.00
IUUC-Cho-024718	Choloepus hoffmanni	52.39	8.00e-118	417.00
IUUC-Cin-025627	Ciona intestinalis	49.42	4.00e-122	432.00
IUUC-Csv-025872	Ciona savignyi	48.48	6.00e-118	414.00
IUUC-Cgl-026647	Colletotrichum gloeosporioides	48.82	1.00e-125	443.00
IUUC-Cne-027095	Cryptococcus neoformans	43.68	6.00e-99	355.00
IUUC-Dre-028525	Danio rerio	47.80	3.00e-106	379.00
IUUC-Dno-029680	Dasypus novemcinctus	50.00	1.00e-122	434.00
IUUC-Dor-030902	Dipodomys ordii	44.84	2.00e-102	366.00
IUUC-Dse-031197	Dothistroma septosporum	48.93	3.00e-125	442.00
IUUC-Dme-032122	Drosophila melanogaster	47.52	3.00e-116	412.00
IUUC-Ete-032966	Echinops telfairi	42.00	1.00e-93	335.00
IUUC-Eca-033915	Equus caballus	49.64	2.00e-120	426.00
IUUC-Eeu-034963	Erinaceus europaeus	49.64	1.00e-120	427.00
IUUC-Fca-035824	Felis catus	50.00	1.00e-122	434.00
IUUC-Fal-036687	Ficedula albicollis	41.76	6.00e-91	326.00
IUUC-Fox-037756	Fusarium oxysporum	49.53	4.00e-128	452.00
IUUC-Fso-038464	Fusarium solani	50.83	3.00e-128	452.00
IUUC-Gmo-039073	Gadus morhua	49.76	1.00e-121	431.00
IUUC-Ggr-039946	Gaeumannomyces graminis	51.18	9.00e-129	454.00
IUUC-Gga-040309	Gallus gallus	53.75	4.00e-98	348.00
IUUC-Gac-042430	Gasterosteus aculeatus	50.00	3.00e-122	432.00
IUUC-Gma-042956	Glycine max	53.10	2.00e-136	479.00
IUUC-Ggo-044465	Gorilla gorilla	42.00	2.00e-94	338.00
IUUC-Hsa-046879	Homo sapiens	50.00	1.00e-122	434.00
IUUC-Hvu-047697	Hordeum vulgare	53.05	3.00e-134	472.00
IUUC-Itr-048430	Ictidomys tridecemlineatus	50.00	4.00e-123	434.00
IUUC-Kpa-049228	Komagataella pastoris	49.29	2.00e-122	432.00
IUUC-Lch-050252	Latimeria chalumnae	50.36	2.00e-122	432.00
IUUC-Lpe-051550	Leersia perrieri	53.52	4.00e-137	481.00
IUUC-Loc-052472	Lepisosteus oculatus	50.48	3.00e-123	436.00
IUUC-Lma-053159	Leptosphaeria maculans	49.07	3.00e-126	446.00
IUUC-Laf-054154	Loxodonta africana	50.00	9.00e-123	434.00
IUUC-Mcc-055085	Macaca mulatta	50.00	9.00e-123	434.00
IUUC-Meu-056751	Macropus eugenii	42.24	3.00e-70	258.00
IUUC-Mor-057201	Magnaporthe oryzae	51.42	5.00e-130	458.00
IUUC-Mpo-057597	Magnaporthe poae	51.18	6.00e-129	454.00
IUUC-Mtr-057633	Medicago truncatula	53.52	5.00e-136	478.00
IUUC-Mla-058888	Melampsora laricipopulina	45.43	2.00e-109	386.00
IUUC-Mga-059935	Meleagris gallopavo	41.76	4.00e-91	327.00
IUUC-Mvi-060320	Microbotryum violaceum	48.57	1.00e-116	414.00
IUUC-Mmr-060820	Microcebus murinus	50.00	9.00e-123	434.00
IUUC-Mdo-062930	Monodelphis domestica	50.24	3.00e-123	436.00
IUUC-Mmu-063601	Mus musculus	50.00	1.00e-122	434.00
IUUC-Mac-065229	Musa acuminata	53.43	3.00e-136	478.00
IUUC-Mpu-066653	Mustela putorius furo	50.00	9.00e-123	434.00
IUUC-Mlu-067418	Myotis lucifugus	50.00	6.00e-123	434.00
IUUC-Nfi-068278	Neosartorya fischeri	51.31	3.00e-128	452.00
IUUC-Ncr-068813	Neurospora crassa	52.14	8.00e-133	467.00
IUUC-Nle-069418	Nomascus leucogenys	50.00	1.00e-122	434.00
IUUC-Opr-070585	Ochotona princeps	44.09	8.00e-94	335.00
IUUC-Ont-071300	Oreochromis niloticus	50.00	5.00e-122	432.00
IUUC-Oan-073046	Ornithorhynchus anatinus	50.00	4.00e-122	432.00
IUUC-Ocu-074178	Oryctolagus cuniculus	50.00	5.00e-123	435.00
IUUC-Oba-075757	Oryza barthii	53.52	4.00e-137	481.00
IUUC-Obr-076553	Oryza brachyantha	53.52	2.00e-136	479.00
IUUC-Ogl-077520	Oryza glaberrima	53.52	7.00e-137	481.00
IUUC-Ogu-078278	Oryza glumaepatula	53.52	5.00e-137	481.00
IUUC-Oin-079767	Oryza indica	53.52	6.00e-137	481.00
IUUC-Olo-080380	Oryza longistaminata	53.02	6.00e-135	474.00
IUUC-Ome-081925	Oryza meridionalis	53.02	4.00e-135	475.00
IUUC-Oni-082619	Oryza nivara	53.52	6.00e-137	481.00
IUUC-Opu-083684	Oryza punctata	53.02	3.00e-135	476.00
IUUC-Oru-084501	Oryza rufipogon	53.52	5.00e-137	481.00
IUUC-Osa-086251	Oryza sativa	53.52	8.00e-136	475.00
IUUC-Ola-086777	Oryzias latipes	40.74	8.00e-90	322.00
IUUC-Olu-087813	Ostreococcus lucimarinus	49.88	4.00e-115	405.00
IUUC-Oga-088903	Otolemur garnettii	50.00	1.00e-122	434.00
IUUC-Oar-090210	Ovis aries	50.00	9.00e-123	434.00
IUUC-Ptr-090529	Pan troglodytes	42.00	2.00e-93	334.00
IUUC-Pan-092368	Papio anubis	48.70	3.00e-108	386.00
IUUC-Psi-093969	Pelodiscus sinensis	41.76	7.00e-92	329.00
IUUC-Pma-094364	Petromyzon marinus	40.99	4.00e-82	296.00
IUUC-Pno-094871	Phaeosphaeria nodorum	49.07	5.00e-126	445.00
IUUC-Ppa-095834	Physcomitrella patens	52.25	1.00e-132	467.00
IUUC-Pfo-096232	Poecilia formosa	50.00	2.00e-122	433.00
IUUC-Pab-098583	Pongo abelii	50.00	1.00e-122	434.00
IUUC-Pop-099468	Populus trichocarpa	52.18	4.00e-136	478.00
IUUC-Pca-100596	Procavia capensis	44.85	3.00e-90	324.00
IUUC-Ppe-101641	Prunus persica	52.75	2.00e-137	483.00
IUUC-Pva-102116	Pteropus vampyrus	46.78	3.00e-109	389.00
IUUC-Pgr-103465	Puccinia graminis	45.45	3.00e-115	409.00
IUUC-Ptt-103813	Puccinia triticina	41.88	6.00e-103	368.00
IUUC-Pte-104018	Pyrenophora teres	49.07	5.00e-125	441.00
IUUC-Pyt-104713	Pyrenophora triticirepentis	49.64	7.00e-125	441.00
IUUC-Rno-105153	Rattus norvegicus	42.23	2.00e-93	335.00
IUUC-Sce-106449	Saccharomyces cerevisiae	45.32	8.00e-111	394.00
IUUC-Sha-106961	Sarcophilus harrisii	50.24	4.00e-123	435.00
IUUC-Sja-107814	Schizosaccharomyces japonicus	40.42	9.00e-127	447.00
IUUC-Spo-108024	Schizosaccharomyces pombe	50.48	1.00e-126	447.00
IUUC-Ssl-108514	Sclerotinia sclerotiorum	42.63	3.00e-88	317.00
IUUC-Smo-109640	Selaginella moellendorffii	52.96	7.00e-135	474.00
IUUC-Sit-110598	Setaria italica	54.46	5.00e-138	484.00
IUUC-Sly-111706	Solanum lycopersicum	52.62	3.00e-138	485.00
IUUC-Stu-112894	Solanum tuberosum	29.78	1.00e-49	189.00
IUUC-Sar-113291	Sorex araneus	49.76	3.00e-119	422.00
IUUC-Sbi-114042	Sorghum bicolor	54.23	4.00e-138	485.00
IUUC-Sre-114958	Sporisorium reilianum	50.00	1.00e-126	444.00
IUUC-Ssc-115754	Sus scrofa	50.00	1.00e-122	434.00
IUUC-Tgu-116632	Taeniopygia guttata	43.31	2.00e-92	331.00
IUUC-Tru-118570	Takifugu rubripes	49.76	5.00e-122	432.00
IUUC-Tsy-119407	Tarsius syrichta	46.76	3.00e-93	333.00
IUUC-Tni-120836	Tetraodon nigroviridis	51.55	4.00e-120	425.00
IUUC-Tca-121479	Theobroma cacao	53.52	3.00e-137	482.00
IUUC-Tre-121909	Trichoderma reesei	50.59	6.00e-130	458.00
IUUC-Tvi-122370	Trichoderma virens	50.59	1.00e-128	453.00
IUUC-Tae-125214	Triticum aestivum	52.30	1.00e-133	469.00
IUUC-Tme-127172	Tuber melanosporum	49.04	7.00e-125	441.00
IUUC-Tbe-127793	Tupaia belangeri	43.45	2.00e-86	311.00
IUUC-Ttr-129253	Tursiops truncatus	50.00	1.00e-122	433.00
IUUC-Uma-129355	Ustilago maydis	50.71	1.00e-128	451.00
IUUC-Vda-129886	Verticillium dahliae	50.23	5.00e-127	448.00
IUUC-Vpa-130708	Vicugna pacos	50.00	3.00e-122	432.00
IUUC-Vvi-131078	Vitis vinifera	52.16	2.00e-137	482.00
IUUC-Xtr-132123	Xenopus tropicalis	48.21	4.00e-112	399.00
IUUC-Xma-133869	Xiphophorus maculatus	50.00	1.00e-122	433.00
IUUC-Yli-134657	Yarrowia lipolytica	49.06	1.00e-126	446.00
IUUC-Zma-135570	Zea mays	53.76	2.00e-137	483.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence