iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000011165.4	ENSCAFT00000048296.2	ENSCAFP00000037168.1
ENSCAFG00000011165.4	ENSCAFT00000017755.3	ENSCAFP00000016436.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.80e-69	234.8	69	504

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw...kskkkavsprellkalkkeaeefsgy 87
           Gl NlgNtC+mNS+LQ Ls++p + + l e +++ +++++++ p++ l+ +l +l+++l     +++++ + + ll++l+++  ++s++
   Q: 69   GLVNLGNTCFMNSLLQGLSACPAFIKWLEEFTTQYTRDQKETPPHQYLSLTLLHLLKALScqeVTDDEVLDASCLLDVLRMYRWQISSF 157
           9*****************************88888888888999***************888899999********************* PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde..........aeekkkkknkslisdlFqgqlksqikclecdnvs.sr 165
           e+qDa+E+++++ ++le+e    ++ +++++++ ++ e++ e          + + ++++n+   ++ F+g+l+s+++c++c+++s +r
   Q: 158  EEQDAHELFHVITSSLEDER--DRQPRVTHLFDVHSLEQQPEitpkqitcrtRGSPHPTSNHWKSQHPFHGRLTSNMVCKHCEHQSpVR 244
           *******************9..678889999999988888888999999999999********************************** PP
   S: 166  eepfldlslpvpgke...etkkeslqdcLesftkeeelegenkyycekck...............kkqeaekklklkklPevLilhLkR 236
           +++f +lsl++p  +   + ++++l++cL++f + e++++   + c++c+               ++++ +k+lkl klP++L++hL+R
   Q: 245  FDTFDSLSLSIPAATwvlKGHPLTLDHCLHHFISSESVRD---VVCDNCTqieakgtlngekvehQRTTFVKQLKLGKLPQCLCIHLQR 330
           ************88722234566***************97...9******8888888888888777777******************** PP
   S: 237  fsfseeqksrekinkkvefpleLdlspfcts..................................peekqke................. 274
            s+s++ + + k +++v+f++ L ++ +  +                                  +     +                 
   Q: 331  LSWSSH-GTPLKRHEHVQFNEFLMMDIYKYHllghkpgqhspkpsettgptldlqdgpatpksvlS-----Qpggpktqifmngacspt 413
           ***998.8888*********8888875555555777777766666666666666666555555550.....055555555555566666 PP
   S: 275  ......................kkkYeLiavvvHsGslssGHYvayvkn.........ekgkWllfdDskVtevkeeevleetgstaYv 332
                                  + ++L+avvvH+G ++sGH+v+y ++         ++++Wl ++D++V++ + +evl+   s+aY+
   Q: 414  llpplpapmpfplpvvpdysssMYLFRLMAVVVHHGDMHSGHFVTYRRSppsaknplsTSNQWLWISDDTVRKASLQEVLS---SSAYL 499
           66666666666666666666559999***********************9999888888999*******************...***** PP
   S: 333  lfYkr 337
           lfY+r
   Q: 500  LFYER 504
           ***98 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

ILSSRAQGGV TGADRPIQGF LSPGVGVRYK VMKNWGVIGG IAAALAAGIY VIWGPITERK 60
KRRKGLVPGL VNLGNTCFMN SLLQGLSACP AFIKWLEEFT TQYTRDQKET PPHQYLSLTL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCTGATCCT GTCACTATGG TCATCACCCT CATCACCAAC ACCATCATCA TCACCACCAT 60
CATCATTACA CTATCATCAC CACCACCACC ACCATGGTCG TCATCACTAT CCTCCTCCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005741--C:mitochondrial outer membrane
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008053--P:mitochondrial fusion
GO:0000422--P:mitophagy
GO:0035871--P:protein K11-linked deubiquitination
GO:0044313--P:protein K6-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000204	Aegilops tauschii	27.91	7.00e-15	75.50
IUUC-Aml-001733	Ailuropoda melanoleuca	95.00	0.00e+00	899.00
IUUC-Atr-002510	Amborella trichopoda	24.42	1.00e-20	94.70
IUUC-Apl-003645	Anas platyrhynchos	73.40	5.00e-104	370.00
IUUC-Aca-004583	Anolis carolinensis	68.42	4.00e-24	102.00
IUUC-Aly-005754	Arabidopsis lyrata	25.52	2.00e-23	103.00
IUUC-Ath-007622	Arabidopsis thaliana	26.82	2.00e-23	103.00
IUUC-Acl-008136	Aspergillus clavatus	22.20	3.00e-12	67.00
IUUC-Ame-010896	Astyanax mexicanus	61.30	7.00e-150	523.00
IUUC-Bta-012321	Bos taurus	91.27	0.00e+00	848.00
IUUC-Bdi-014795	Brachypodium distachyon	27.71	6.00e-16	78.60
IUUC-Bol-015637	Brassica oleracea	26.15	5.00e-23	102.00
IUUC-Bra-016801	Brassica rapa	25.89	1.00e-23	103.00
IUUC-Cel-018308	Caenorhabditis elegans	27.95	4.00e-35	142.00
IUUC-Cja-018826	Callithrix jacchus	91.17	0.00e+00	872.00
IUUC-Cpo-021343	Cavia porcellus	90.28	0.00e+00	838.00
IUUC-Csa-023419	Chlorocebus sabaeus	90.96	0.00e+00	871.00
IUUC-Cho-024475	Choloepus hoffmanni	88.85	5.00e-138	484.00
IUUC-Cgl-026621	Colletotrichum gloeosporioides	21.34	4.00e-12	66.60
IUUC-Cne-027061	Cryptococcus neoformans	25.19	3.00e-10	60.80
IUUC-Dre-027563	Danio rerio	57.52	1.00e-151	529.00
IUUC-Dno-029929	Dasypus novemcinctus	90.19	0.00e+00	875.00
IUUC-Dor-030166	Dipodomys ordii	80.58	0.00e+00	732.00
IUUC-Dme-031627	Drosophila melanogaster	33.56	5.00e-35	142.00
IUUC-Ete-032634	Echinops telfairi	77.69	0.00e+00	674.00
IUUC-Eca-033968	Equus caballus	92.29	0.00e+00	836.00
IUUC-Eeu-035279	Erinaceus europaeus	82.32	2.00e-59	223.00
IUUC-Fca-036525	Felis catus	94.42	0.00e+00	911.00
IUUC-Fal-036606	Ficedula albicollis	77.81	1.00e-158	552.00
IUUC-Gmo-038726	Gadus morhua	55.03	3.00e-139	488.00
IUUC-Gga-040718	Gallus gallus	78.01	1.00e-159	555.00
IUUC-Gac-042645	Gasterosteus aculeatus	56.22	2.00e-144	505.00
IUUC-Gma-042890	Glycine max	25.99	6.00e-26	112.00
IUUC-Ggo-045021	Gorilla gorilla	90.96	0.00e+00	870.00
IUUC-Hsa-045832	Homo sapiens	90.96	0.00e+00	870.00
IUUC-Itr-048392	Ictidomys tridecemlineatus	92.90	0.00e+00	847.00
IUUC-Lch-050662	Latimeria chalumnae	70.11	8.00e-178	616.00
IUUC-Lpe-051078	Leersia perrieri	25.81	6.00e-29	122.00
IUUC-Loc-052611	Lepisosteus oculatus	64.55	3.00e-173	601.00
IUUC-Lma-053048	Leptosphaeria maculans	21.02	1.00e-15	78.20
IUUC-Laf-053752	Loxodonta africana	91.89	0.00e+00	835.00
IUUC-Mcc-054892	Macaca mulatta	91.35	0.00e+00	875.00
IUUC-Meu-056673	Macropus eugenii	74.09	5.00e-159	553.00
IUUC-Mtr-057976	Medicago truncatula	26.07	5.00e-32	132.00
IUUC-Mla-058970	Melampsora laricipopulina	22.75	1.00e-11	65.10
IUUC-Mga-059543	Meleagris gallopavo	76.64	0.00e+00	655.00
IUUC-Mmr-061534	Microcebus murinus	90.77	0.00e+00	872.00
IUUC-Mdo-062140	Monodelphis domestica	68.17	1.00e-167	583.00
IUUC-Mmu-063673	Mus musculus	87.31	0.00e+00	823.00
IUUC-Mpu-066328	Mustela putorius furo	94.81	0.00e+00	883.00
IUUC-Mlu-067938	Myotis lucifugus	92.50	0.00e+00	904.00
IUUC-Nle-069426	Nomascus leucogenys	91.69	0.00e+00	784.00
IUUC-Opr-070796	Ochotona princeps	85.21	5.00e-121	427.00
IUUC-Ont-072248	Oreochromis niloticus	58.48	1.00e-150	526.00
IUUC-Oan-072916	Ornithorhynchus anatinus	80.89	0.00e+00	746.00
IUUC-Ocu-074459	Oryctolagus cuniculus	86.77	0.00e+00	661.00
IUUC-Oba-075765	Oryza barthii	25.96	6.00e-30	125.00
IUUC-Obr-076005	Oryza brachyantha	26.65	2.00e-31	130.00
IUUC-Ogl-077916	Oryza glaberrima	26.74	7.00e-33	135.00
IUUC-Ogu-078263	Oryza glumaepatula	26.35	1.00e-30	127.00
IUUC-Oin-080096	Oryza indica	27.39	3.00e-24	106.00
IUUC-Ome-081928	Oryza meridionalis	26.71	2.00e-30	127.00
IUUC-Oni-082424	Oryza nivara	26.55	1.00e-30	127.00
IUUC-Oru-085117	Oryza rufipogon	26.55	1.00e-30	127.00
IUUC-Ola-087429	Oryzias latipes	54.71	2.00e-141	495.00
IUUC-Oga-087981	Otolemur garnettii	90.96	0.00e+00	868.00
IUUC-Oar-089927	Ovis aries	90.48	0.00e+00	841.00
IUUC-Ptr-090878	Pan troglodytes	90.96	0.00e+00	870.00
IUUC-Pan-092698	Papio anubis	91.35	0.00e+00	875.00
IUUC-Psi-093451	Pelodiscus sinensis	76.06	0.00e+00	694.00
IUUC-Pfo-096096	Poecilia formosa	57.43	2.00e-151	528.00
IUUC-Pab-098676	Pongo abelii	89.81	0.00e+00	848.00
IUUC-Pca-100418	Procavia capensis	94.70	7.00e-128	450.00
IUUC-Ppe-101898	Prunus persica	25.22	5.00e-18	85.90
IUUC-Pva-103018	Pteropus vampyrus	90.00	0.00e+00	864.00
IUUC-Pgr-103423	Puccinia graminis	26.03	5.00e-09	57.00
IUUC-Pte-104330	Pyrenophora teres	22.03	2.00e-15	77.80
IUUC-Pyt-104518	Pyrenophora triticirepentis	22.41	1.00e-17	85.10
IUUC-Rno-105708	Rattus norvegicus	87.12	0.00e+00	822.00
IUUC-Sha-106971	Sarcophilus harrisii	80.44	0.00e+00	745.00
IUUC-Sit-110442	Setaria italica	25.61	4.00e-25	109.00
IUUC-Stu-112223	Solanum tuberosum	24.16	2.00e-14	73.20
IUUC-Ssc-116397	Sus scrofa	90.38	0.00e+00	858.00
IUUC-Tgu-117446	Taeniopygia guttata	69.88	0.00e+00	636.00
IUUC-Tru-118268	Takifugu rubripes	56.89	3.00e-136	478.00
IUUC-Tsy-119484	Tarsius syrichta	90.55	4.00e-53	202.00
IUUC-Tni-119735	Tetraodon nigroviridis	55.88	3.00e-120	425.00
IUUC-Tca-121660	Theobroma cacao	25.00	4.00e-27	116.00
IUUC-Tae-125383	Triticum aestivum	27.81	4.00e-27	115.00
IUUC-Tur-126458	Triticum urartu	27.81	7.00e-17	82.00
IUUC-Tbe-127740	Tupaia belangeri	84.04	0.00e+00	777.00
IUUC-Ttr-129273	Tursiops truncatus	87.50	0.00e+00	824.00
IUUC-Vvi-131177	Vitis vinifera	24.17	5.00e-25	108.00
IUUC-Xtr-132374	Xenopus tropicalis	65.09	1.00e-166	579.00
IUUC-Xma-133267	Xiphophorus maculatus	59.52	1.00e-152	532.00
IUUC-Zma-135796	Zea mays	26.13	3.00e-20	93.20

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence