iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-061863

Ensembl Protein ID

ENSMODP00000040666.1

UniProt Accession

K7E4G4; K7E4G4_MONDO

Protein Name

Uncharacterized protein

Gene Name

NSMCE2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000027668.1	ENSMODT00000043773.1	ENSMODP00000040666.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	1.70e-09	37.7	161	236

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlp.sGitydrssIekwlasggk.....tcPvtrqpl...teedlvPnltlrrliqawce 70
             f+CpI+   M+ Pv  + +G+ty+ ++I++ ++s++k      cP+ + +    + +dlv   +lrr i++++ 
   Q: 161  TNFICPITQLEMKKPVKNKvCGHTYEEEAIRRIIESKHKrmkkaCCPKIGCSHtdvKLTDLVQDVVLRRAIENHRR 236
           57************************************99***9777655444222669999*********99876 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MPENSDDFPW VFVNNVDNAL GSLKNCQAYI TAGMQSVNNI ALDLVVTQTD TDGDSNMENL 60
LFEYIEMERD LNQYMTAVEA TLSQVKDKDY LNLTPDLKAL VEEKLVTLKS SNTEEDLKKD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGGAGATCTC TGAGGTCCCT TCACTTTCTA ACCTTCACCA ATGCACCCGA GAATGGCAGG 60
GACTGATTTG GTAAGGGGTT ATCTCTTCCC CCGCCCCGCA TCATCGAGGA TCCTTACTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR026846--Nse2(Mms21)
IPR003613--Ubox_domain
IPR004181--Znf_MIZ
IPR013083--Znf_RING/FYVE/PHD

Pfam

PF11789--zf-Nse

SMART

SM00504--Ubox

Gene Ontology

GO:0000781--C:chromosome, telomeric region
GO:0016605--C:PML body
GO:0030915--C:Smc5-Smc6 complex
GO:0019789--F:SUMO transferase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0090398--P:cellular senescence
GO:0000724--P:double-strand break repair via homologous recombination
GO:0034184--P:positive regulation of maintenance of mitotic sister chromatid cohesion
GO:0045842--P:positive regulation of mitotic metaphase/anaphase transition
GO:0000722--P:telomere maintenance via recombination

KEGG

mdo:100032252

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000276	Aegilops tauschii	29.17	7.00e-07	47.40
IUUC-Aml-001627	Ailuropoda melanoleuca	57.96	1.00e-63	236.00
IUUC-Atr-002438	Amborella trichopoda	32.26	3.00e-07	48.90
IUUC-Apl-004091	Anas platyrhynchos	63.27	1.00e-29	120.00
IUUC-Aca-004433	Anolis carolinensis	46.55	5.00e-57	213.00
IUUC-Aly-006133	Arabidopsis lyrata	24.42	3.00e-09	55.50
IUUC-Ath-007424	Arabidopsis thaliana	26.73	8.00e-12	63.90
IUUC-Ago-007852	Ashbya gossypii	30.68	9.00e-10	56.60
IUUC-Ame-010902	Astyanax mexicanus	37.12	3.00e-38	151.00
IUUC-Bgr-012088	Blumeria graminis	27.63	4.00e-04	39.30
IUUC-Bta-013397	Bos taurus	62.79	2.00e-43	168.00
IUUC-Bci-013738	Botrytis cinerea	27.55	3.00e-04	39.70
IUUC-Bdi-014403	Brachypodium distachyon	29.87	2.00e-07	48.90
IUUC-Bol-015454	Brassica oleracea	24.47	6.00e-08	50.80
IUUC-Cel-018588	Caenorhabditis elegans	35.48	3.00e-03	34.70
IUUC-Cja-019246	Callithrix jacchus	57.92	5.00e-65	240.00
IUUC-Cpo-021670	Cavia porcellus	57.66	9.00e-57	213.00
IUUC-Csa-023982	Chlorocebus sabaeus	55.90	1.00e-60	226.00
IUUC-Cin-025127	Ciona intestinalis	24.46	2.00e-15	75.50
IUUC-Cgl-026430	Colletotrichum gloeosporioides	31.17	7.00e-07	48.10
IUUC-Cne-026806	Cryptococcus neoformans	26.70	2.00e-10	59.30
IUUC-Cme-027175	Cyanidioschyzon merolae	31.94	9.00e-06	44.30
IUUC-Dre-028325	Danio rerio	33.33	2.00e-29	122.00
IUUC-Dno-029735	Dasypus novemcinctus	55.70	8.00e-72	263.00
IUUC-Dor-030454	Dipodomys ordii	42.20	3.00e-38	151.00
IUUC-Dse-031273	Dothistroma septosporum	30.26	3.00e-04	40.00
IUUC-Dme-031971	Drosophila melanogaster	28.83	3.00e-08	52.00
IUUC-Ete-032838	Echinops telfairi	43.59	6.00e-30	122.00
IUUC-Eca-034371	Equus caballus	57.85	3.00e-72	264.00
IUUC-Eeu-035258	Erinaceus europaeus	55.61	1.00e-46	179.00
IUUC-Fca-035576	Felis catus	51.77	1.00e-59	223.00
IUUC-Fal-037038	Ficedula albicollis	46.55	3.00e-60	224.00
IUUC-Fox-037843	Fusarium oxysporum	29.73	1.00e-04	40.80
IUUC-Fso-038272	Fusarium solani	32.91	1.00e-04	40.80
IUUC-Ggr-040059	Gaeumannomyces graminis	29.11	2.00e-05	43.50
IUUC-Gga-040737	Gallus gallus	41.29	3.00e-47	181.00
IUUC-Gac-042591	Gasterosteus aculeatus	36.24	2.00e-33	135.00
IUUC-Gma-043177	Glycine max	26.56	2.00e-11	62.80
IUUC-Ggo-045206	Gorilla gorilla	55.16	8.00e-61	226.00
IUUC-Hsa-046704	Homo sapiens	55.16	2.00e-60	225.00
IUUC-Hvu-047252	Hordeum vulgare	28.08	1.00e-07	50.40
IUUC-Itr-048972	Ictidomys tridecemlineatus	81.52	3.00e-34	137.00
IUUC-Kpa-049181	Komagataella pastoris	32.56	2.00e-08	53.10
IUUC-Lpe-051150	Leersia perrieri	24.74	3.00e-06	45.40
IUUC-Loc-052687	Lepisosteus oculatus	39.30	3.00e-37	148.00
IUUC-Lma-053255	Leptosphaeria maculans	27.27	5.00e-05	42.70
IUUC-Laf-054270	Loxodonta africana	55.23	3.00e-65	241.00
IUUC-Mcc-054757	Macaca mulatta	57.45	7.00e-49	186.00
IUUC-Mor-057028	Magnaporthe oryzae	30.56	6.00e-06	45.40
IUUC-Mpo-057462	Magnaporthe poae	31.65	6.00e-07	48.90
IUUC-Mtr-058011	Medicago truncatula	26.60	2.00e-10	58.90
IUUC-Mga-059215	Meleagris gallopavo	62.07	6.00e-30	122.00
IUUC-Mvi-060511	Microbotryum violaceum	28.95	2.00e-05	43.50
IUUC-Mmr-061584	Microcebus murinus	53.19	5.00e-54	204.00
IUUC-Mmu-064413	Mus musculus	54.82	2.00e-64	238.00
IUUC-Mac-065639	Musa acuminata	31.09	7.00e-06	44.30
IUUC-Mpu-066092	Mustela putorius furo	48.79	8.00e-59	220.00
IUUC-Mlu-068198	Myotis lucifugus	58.74	2.00e-72	265.00
IUUC-Nle-070109	Nomascus leucogenys	55.16	2.00e-61	228.00
IUUC-Opr-070540	Ochotona princeps	69.57	3.00e-26	111.00
IUUC-Ont-071575	Oreochromis niloticus	36.68	2.00e-36	145.00
IUUC-Oan-072777	Ornithorhynchus anatinus	73.63	3.00e-24	102.00
IUUC-Ocu-074730	Oryctolagus cuniculus	57.27	2.00e-63	235.00
IUUC-Obr-076506	Oryza brachyantha	29.03	1.00e-08	52.80
IUUC-Ogu-079018	Oryza glumaepatula	25.31	4.00e-06	44.70
IUUC-Oin-079792	Oryza indica	23.68	5.00e-06	44.30
IUUC-Ome-081426	Oryza meridionalis	23.68	4.00e-06	44.70
IUUC-Oni-082286	Oryza nivara	24.08	4.00e-06	44.70
IUUC-Opu-083586	Oryza punctata	27.70	2.00e-05	42.70
IUUC-Oru-085158	Oryza rufipogon	24.08	4.00e-06	44.70
IUUC-Oga-087925	Otolemur garnettii	57.83	2.00e-56	212.00
IUUC-Oar-090138	Ovis aries	49.22	2.00e-54	205.00
IUUC-Ptr-091582	Pan troglodytes	55.16	2.00e-60	225.00
IUUC-Pan-092890	Papio anubis	56.05	3.00e-60	224.00
IUUC-Psi-093714	Pelodiscus sinensis	50.43	1.00e-61	229.00
IUUC-Pma-094198	Petromyzon marinus	29.63	6.00e-18	83.20
IUUC-Pno-094931	Phaeosphaeria nodorum	32.53	2.00e-04	40.40
IUUC-Pab-098005	Pongo abelii	54.71	2.00e-60	224.00
IUUC-Pop-099559	Populus trichocarpa	26.06	7.00e-08	51.20
IUUC-Pca-100368	Procavia capensis	48.91	8.00e-37	146.00
IUUC-Ppe-101873	Prunus persica	26.42	9.00e-10	57.00
IUUC-Pva-102951	Pteropus vampyrus	56.94	9.00e-66	243.00
IUUC-Pte-104390	Pyrenophora teres	38.57	3.00e-06	46.20
IUUC-Pyt-104633	Pyrenophora triticirepentis	38.03	1.00e-05	44.70
IUUC-Rno-105346	Rattus norvegicus	54.70	6.00e-65	240.00
IUUC-Sce-106198	Saccharomyces cerevisiae	24.18	1.00e-04	40.00
IUUC-Sha-107586	Sarcophilus harrisii	85.80	1.00e-61	228.00
IUUC-Sja-107983	Schizosaccharomyces japonicus	35.87	3.00e-10	58.50
IUUC-Spo-108327	Schizosaccharomyces pombe	24.73	5.00e-04	38.10
IUUC-Ssl-108555	Sclerotinia sclerotiorum	32.05	7.00e-05	42.00
IUUC-Sit-109919	Setaria italica	24.73	6.00e-07	48.10
IUUC-Sly-111667	Solanum lycopersicum	29.47	1.00e-05	43.50
IUUC-Stu-112211	Solanum tuberosum	31.58	2.00e-06	45.80
IUUC-Sar-113609	Sorex araneus	52.14	2.00e-54	205.00
IUUC-Sbi-113916	Sorghum bicolor	23.48	1.00e-07	49.70
IUUC-Sre-115187	Sporisorium reilianum	26.21	1.00e-05	43.90
IUUC-Tgu-116472	Taeniopygia guttata	46.70	5.00e-56	210.00
IUUC-Tru-117771	Takifugu rubripes	33.90	2.00e-30	125.00
IUUC-Tni-119821	Tetraodon nigroviridis	32.76	4.00e-31	127.00
IUUC-Tca-121272	Theobroma cacao	27.52	3.00e-06	45.40
IUUC-Tre-122049	Trichoderma reesei	29.27	1.00e-06	47.40
IUUC-Tvi-122642	Trichoderma virens	31.67	1.00e-05	44.30
IUUC-Tae-122969	Triticum aestivum	29.17	7.00e-07	47.40
IUUC-Tur-126346	Triticum urartu	30.56	6.00e-08	50.80
IUUC-Tme-126988	Tuber melanosporum	31.25	5.00e-08	52.00
IUUC-Tbe-127676	Tupaia belangeri	51.78	1.00e-47	182.00
IUUC-Ttr-128602	Tursiops truncatus	58.30	3.00e-65	241.00
IUUC-Uma-129520	Ustilago maydis	28.00	1.00e-04	40.40
IUUC-Vpa-130510	Vicugna pacos	58.41	6.00e-66	243.00
IUUC-Vvi-131486	Vitis vinifera	29.63	4.00e-13	68.20
IUUC-Yli-134676	Yarrowia lipolytica	29.85	1.00e-05	43.50

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence