iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TCM_022374	EOY08055	EOY08055
TCM_022374	EOY08054	EOY08054
TCM_022374	EOY08057	EOY08057
TCM_022374	EOY08059	EOY08059
TCM_022374	EOY08058	EOY08058

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.40e-103	347.8	819	1165

Active Site

Position(s)	Description	Evidence
1133	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksf 96
           s+lk++++v+fv      E+gld+gG+++efl+ +ske + p++glf +++++++ l pnp++ + + + +++ eflGr++gkal++g lld+ +s++f
   Q: 819  SRLKSSIHVSFVSecglpEAGLDYGGLSKEFLTDISKEAFAPEYGLFSQTSTSDRLLIPNPAARYLE-NGIQMIEFLGRVVGKALYEGILLDYSFSHVF 916
           6899*********999999*******************************************99865.******************************* PP
   S: 97   yklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafre 195
            ++llg+   l++l+++dpely++l+++k++ + di+el+ld+t+  +ee++g++++ eLkpgG+++ VtneNk +Yv+++++y+l+++i    +af++
   Q: 917  VQKLLGRYSFLDELSTLDPELYRNLMYVKHY-DGDIKELCLDFTI--TEESFGKRHVIELKPGGKDVCVTNENKMQYVHAMADYKLNRQILPFSNAFYR 1012
           ********999********************.6799987666666..5888************************************************ PP
   S: 196  GfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelkprlfvirk.. 291
           G++++i++++l+lF+++el++l++G  ++idv+dl+++t+y+ggy+e s++i+ Fw+v+++f+ +er+++L+FvT++sr+Pl Gf+ l+p+ f+i+k  
   Q: 1013 GLTDLISPSWLKLFNASELNQLLSGGdHDIDVDDLRNNTRYTGGYSEGSRTIKLFWQVMKDFEPKERCMLLKFVTSCSRAPLLGFKFLQPS-FTIHKva 1110
           ************************999**************************************************************88.999999* PP
   S: 292  ..........dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
                       + +rlPs++TC+n+LkLP+Y+  ++lk kL+yAi++++gFels
   Q: 1111 sdaplwatigGPDVERLPSASTCYNTLKLPTYKRSSTLKAKLRYAISSNAGFELS 1165
           ********955555**************************************985 PP

Organism

Theobroma cacao

Protein Sequence
(Fasta)

MEEPRKHQVS LRGASAKEIS RDALLEKVSQ ERENRNYARR AASAAIFIQR VWRSYNVTMK 60
VAIKLQEEWE SFVKNQAELM TANLISSSVL RPFIFFITCL SIRRRKILAR VSNCMQTCFK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTTTCCCGT TGACGAAAGC TAAAATGGAA AGAAAAGAAA TTAAGATTTC ATTAGCTTCC 60
CTTAGATGAT CGTCTCTCAG CCATGGAGGA ACCTCGGAAA CATCAGGTCA GTCCACTCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	57.82	0.00e+00	1099.00
IUUC-Aml-002107	Ailuropoda melanoleuca	39.18	3.00e-111	395.00
IUUC-Atr-003017	Amborella trichopoda	58.12	0.00e+00	1341.00
IUUC-Apl-003328	Anas platyrhynchos	39.36	1.00e-112	400.00
IUUC-Aly-005794	Arabidopsis lyrata	60.78	0.00e+00	1375.00
IUUC-Ath-007269	Arabidopsis thaliana	61.16	0.00e+00	1424.00
IUUC-Ago-007748	Ashbya gossypii	40.09	2.00e-79	289.00
IUUC-Acl-008158	Aspergillus clavatus	38.45	1.00e-76	280.00
IUUC-Afl-008398	Aspergillus flavus	40.13	2.00e-79	290.00
IUUC-Afu-008937	Aspergillus fumigatus	39.33	2.00e-78	286.00
IUUC-Ani-009252	Aspergillus nidulans	39.29	1.00e-84	307.00
IUUC-Ang-009773	Aspergillus niger	37.82	1.00e-75	277.00
IUUC-Aor-009940	Aspergillus oryzae	40.13	1.00e-79	290.00
IUUC-Ate-010395	Aspergillus terreus	38.91	6.00e-78	285.00
IUUC-Bgr-012269	Blumeria graminis	40.64	1.00e-76	279.00
IUUC-Bta-013547	Bos taurus	39.18	3.00e-112	399.00
IUUC-Bdi-014502	Brachypodium distachyon	56.67	0.00e+00	1204.00
IUUC-Bol-015093	Brassica oleracea	62.10	0.00e+00	1407.00
IUUC-Bra-016722	Brassica rapa	62.36	0.00e+00	1429.00
IUUC-Cel-018447	Caenorhabditis elegans	36.49	4.00e-95	342.00
IUUC-Cja-019855	Callithrix jacchus	39.18	6.00e-112	397.00
IUUC-Cfa-020066	Canis familiaris	37.97	3.00e-105	375.00
IUUC-Cpo-021504	Cavia porcellus	39.54	6.00e-113	401.00
IUUC-Cre-022673	Chlamydomonas reinhardtii	47.17	3.00e-110	392.00
IUUC-Csa-023579	Chlorocebus sabaeus	39.36	2.00e-112	400.00
IUUC-Cin-025750	Ciona intestinalis	38.39	3.00e-104	372.00
IUUC-Csv-026016	Ciona savignyi	39.25	5.00e-109	388.00
IUUC-Cgl-026559	Colletotrichum gloeosporioides	35.47	1.00e-88	320.00
IUUC-Cne-026841	Cryptococcus neoformans	35.79	3.00e-90	325.00
IUUC-Dre-028271	Danio rerio	39.89	5.00e-114	405.00
IUUC-Dno-029054	Dasypus novemcinctus	39.01	2.00e-111	396.00
IUUC-Dor-030938	Dipodomys ordii	37.99	1.00e-105	377.00
IUUC-Dse-031416	Dothistroma septosporum	38.16	3.00e-80	292.00
IUUC-Dme-031602	Drosophila melanogaster	38.27	5.00e-110	391.00
IUUC-Eca-034411	Equus caballus	39.18	3.00e-112	399.00
IUUC-Eeu-035201	Erinaceus europaeus	34.53	2.00e-74	273.00
IUUC-Fca-036594	Felis catus	38.83	4.00e-110	392.00
IUUC-Fal-037317	Ficedula albicollis	39.36	2.00e-112	400.00
IUUC-Fox-037788	Fusarium oxysporum	34.84	2.00e-86	313.00
IUUC-Fso-038088	Fusarium solani	34.00	2.00e-82	300.00
IUUC-Gmo-039412	Gadus morhua	39.54	4.00e-112	398.00
IUUC-Ggr-039941	Gaeumannomyces graminis	40.04	9.00e-86	311.00
IUUC-Gga-040149	Gallus gallus	39.36	1.00e-112	400.00
IUUC-Gac-042088	Gasterosteus aculeatus	39.54	3.00e-111	395.00
IUUC-Gma-042728	Glycine max	67.66	0.00e+00	1585.00
IUUC-Ggo-045279	Gorilla gorilla	39.18	7.00e-112	397.00
IUUC-Hsa-045660	Homo sapiens	39.18	8.00e-112	397.00
IUUC-Hvu-047102	Hordeum vulgare	57.31	0.00e+00	1090.00
IUUC-Lch-050664	Latimeria chalumnae	38.83	1.00e-110	393.00
IUUC-Lpe-050755	Leersia perrieri	51.83	0.00e+00	1047.00
IUUC-Loc-052791	Lepisosteus oculatus	39.47	8.00e-111	394.00
IUUC-Lma-053096	Leptosphaeria maculans	40.21	9.00e-86	311.00
IUUC-Laf-053902	Loxodonta africana	39.43	4.00e-112	398.00
IUUC-Mcc-054730	Macaca mulatta	39.36	2.00e-112	400.00
IUUC-Meu-056527	Macropus eugenii	34.64	8.00e-90	324.00
IUUC-Mor-057021	Magnaporthe oryzae	38.89	6.00e-79	288.00
IUUC-Mpo-057570	Magnaporthe poae	38.97	2.00e-83	303.00
IUUC-Mtr-057671	Medicago truncatula	66.24	0.00e+00	1548.00
IUUC-Mga-059260	Meleagris gallopavo	39.36	2.00e-112	400.00
IUUC-Mmr-060804	Microcebus murinus	39.01	6.00e-112	398.00
IUUC-Mdo-062575	Monodelphis domestica	39.18	1.00e-109	390.00
IUUC-Mmu-063636	Mus musculus	39.22	4.00e-112	398.00
IUUC-Mac-064989	Musa acuminata	57.04	0.00e+00	1189.00
IUUC-Mlu-067952	Myotis lucifugus	39.18	1.00e-111	397.00
IUUC-Nfi-068280	Neosartorya fischeri	39.33	2.00e-78	286.00
IUUC-Ncr-068869	Neurospora crassa	35.96	4.00e-84	305.00
IUUC-Nle-069153	Nomascus leucogenys	39.18	6.00e-112	398.00
IUUC-Opr-070554	Ochotona princeps	39.36	9.00e-112	397.00
IUUC-Ont-071372	Oreochromis niloticus	39.72	2.00e-112	399.00
IUUC-Ocu-074183	Oryctolagus cuniculus	39.18	5.00e-112	398.00
IUUC-Oba-075213	Oryza barthii	56.39	0.00e+00	1042.00
IUUC-Obr-076320	Oryza brachyantha	56.69	0.00e+00	1148.00
IUUC-Ogl-077093	Oryza glaberrima	56.25	0.00e+00	1198.00
IUUC-Ogu-078235	Oryza glumaepatula	53.48	0.00e+00	1086.00
IUUC-Oin-080058	Oryza indica	55.25	0.00e+00	1159.00
IUUC-Olo-080742	Oryza longistaminata	56.54	0.00e+00	1218.00
IUUC-Ome-081741	Oryza meridionalis	54.48	0.00e+00	1139.00
IUUC-Oni-082616	Oryza nivara	53.83	0.00e+00	1102.00
IUUC-Opu-083529	Oryza punctata	53.85	0.00e+00	1106.00
IUUC-Oru-085128	Oryza rufipogon	55.29	0.00e+00	999.00
IUUC-Osa-085557	Oryza sativa	63.97	0.00e+00	912.00
IUUC-Ola-087337	Oryzias latipes	39.54	3.00e-111	395.00
IUUC-Olu-087902	Ostreococcus lucimarinus	45.48	3.00e-98	351.00
IUUC-Oga-088342	Otolemur garnettii	38.94	8.00e-111	394.00
IUUC-Oar-090234	Ovis aries	38.16	1.00e-106	380.00
IUUC-Ptr-091661	Pan troglodytes	39.01	2.00e-111	396.00
IUUC-Pan-092728	Papio anubis	39.12	7.00e-111	394.00
IUUC-Psi-093251	Pelodiscus sinensis	38.38	6.00e-97	348.00
IUUC-Pma-094195	Petromyzon marinus	39.05	2.00e-111	396.00
IUUC-Ppa-095867	Physcomitrella patens	63.62	0.00e+00	748.00
IUUC-Pfo-097472	Poecilia formosa	39.72	1.00e-112	400.00
IUUC-Pab-098570	Pongo abelii	39.18	1.00e-111	397.00
IUUC-Pop-099058	Populus trichocarpa	67.75	0.00e+00	1110.00
IUUC-Pca-100110	Procavia capensis	36.52	1.00e-99	357.00
IUUC-Ppe-101281	Prunus persica	69.65	0.00e+00	1646.00
IUUC-Pva-102887	Pteropus vampyrus	37.59	3.00e-104	372.00
IUUC-Rno-106028	Rattus norvegicus	37.79	2.00e-95	343.00
IUUC-Sce-106446	Saccharomyces cerevisiae	41.69	3.00e-76	279.00
IUUC-Sha-107331	Sarcophilus harrisii	39.36	3.00e-110	392.00
IUUC-Ssl-108520	Sclerotinia sclerotiorum	39.75	6.00e-85	308.00
IUUC-Smo-109537	Selaginella moellendorffii	44.42	0.00e+00	877.00
IUUC-Sit-109811	Setaria italica	55.34	0.00e+00	1176.00
IUUC-Sly-111013	Solanum lycopersicum	63.49	0.00e+00	1442.00
IUUC-Sbi-114433	Sorghum bicolor	56.57	0.00e+00	1215.00
IUUC-Sre-115038	Sporisorium reilianum	45.91	4.00e-98	352.00
IUUC-Ssc-116103	Sus scrofa	39.18	3.00e-111	395.00
IUUC-Tgu-117275	Taeniopygia guttata	39.36	2.00e-112	399.00
IUUC-Tru-118681	Takifugu rubripes	39.54	2.00e-112	399.00
IUUC-Tre-121892	Trichoderma reesei	40.84	1.00e-90	327.00
IUUC-Tvi-122354	Trichoderma virens	42.29	1.00e-89	323.00
IUUC-Tae-124300	Triticum aestivum	82.25	1.00e-137	481.00
IUUC-Tur-126086	Triticum urartu	55.55	0.00e+00	1076.00
IUUC-Tbe-127461	Tupaia belangeri	35.47	8.00e-88	317.00
IUUC-Ttr-129269	Tursiops truncatus	39.36	9.00e-112	397.00
IUUC-Uma-129343	Ustilago maydis	44.58	7.00e-99	355.00
IUUC-Vda-129748	Verticillium dahliae	36.23	4.00e-72	265.00
IUUC-Vvi-131524	Vitis vinifera	72.17	0.00e+00	1678.00
IUUC-Xtr-132146	Xenopus tropicalis	39.54	1.00e-111	397.00
IUUC-Xma-133526	Xiphophorus maculatus	39.72	2.00e-112	399.00
IUUC-Yli-134496	Yarrowia lipolytica	37.58	5.00e-81	295.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence