iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

mRNA Expression
GEO	FFGED
Protein-protein Interaction
IID	iRefIndex	HINT	Mentha
Post-translational Modifications (PTMs)
CPLM	dbPAF	BioGRID
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 activity/RING/RING	RING	19064926

Classification

Family	E-value	Score	Start	End
E3 activity/RING/RING	9.70e-08	30.9	4	48

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdg...plvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iCl d ++g    +++ CgH fh++C+  w    ++ s + +CP+Cr
   Q: 4    CPICLADDQEGeqfGCLNVCGHKFHLNCIREW----HKYSINLKCPICR 48
           ****9988666677889***************....5689********8 PP

Organism

Saccharomyces cerevisiae

Functional Description
(View)

Required for tolerance to alcohol.

Protein Sequence
(Fasta)

MEECPICLAD DQEGEQFGCL NVCGHKFHLN CIREWHKYSI NLKCPICRVE STHLEVGEGQ 60
HALSINLKMG FMIKNAIDYV GAETTNERNE DDTGEQDQEI EFLSERLRGT LVMDTIKIIQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAAGAGT GTCCTATTTG TTTGGCAGAT GACCAAGAGG GTGAACAATT TGGATGTTTG 60
AACGTTTGCG GGCATAAATT CCACTTAAAC TGTATAAGAG AGTGGCACAA GTATAGTATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0016567--P:protein ubiquitination
GO:0045471--P:response to ethanol
GO:0000921--P:septin ring assembly

KEGG

sce:YPR093C

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000386	Aegilops tauschii	46.81	9.00e-08	48.90
IUUC-Atr-003066	Amborella trichopoda	31.79	2.00e-11	62.00
IUUC-Apl-003634	Anas platyrhynchos	45.83	3.00e-05	42.40
IUUC-Ago-007829	Ashbya gossypii	29.69	1.00e-24	105.00
IUUC-Ani-009169	Aspergillus nidulans	38.30	2.00e-05	42.00
IUUC-Bta-012823	Bos taurus	45.83	3.00e-05	42.40
IUUC-Bdi-014588	Brachypodium distachyon	26.44	7.00e-09	54.70
IUUC-Cpo-021467	Cavia porcellus	45.83	5.00e-05	41.60
IUUC-Cre-022693	Chlamydomonas reinhardtii	32.86	7.00e-06	42.40
IUUC-Cho-024278	Choloepus hoffmanni	45.83	5.00e-05	41.60
IUUC-Cin-025619	Ciona intestinalis	33.85	7.00e-05	39.70
IUUC-Dre-028323	Danio rerio	45.83	4.00e-05	42.00
IUUC-Dor-030690	Dipodomys ordii	39.22	3.00e-05	39.70
IUUC-Dse-031237	Dothistroma septosporum	30.23	4.00e-05	40.00
IUUC-Ete-032985	Echinops telfairi	45.83	3.00e-05	42.40
IUUC-Gmo-039560	Gadus morhua	28.28	2.00e-07	47.00
IUUC-Gac-041830	Gasterosteus aculeatus	45.83	4.00e-05	42.00
IUUC-Gma-043193	Glycine max	28.42	3.00e-08	52.00
IUUC-Hvu-047154	Hordeum vulgare	28.48	1.00e-08	53.50
IUUC-Lpe-051373	Leersia perrieri	33.00	4.00e-10	57.00
IUUC-Loc-052174	Lepisosteus oculatus	45.83	1.00e-05	43.50
IUUC-Mla-059005	Melampsora laricipopulina	39.68	3.00e-05	41.60
IUUC-Mmr-061666	Microcebus murinus	45.83	3.00e-05	42.40
IUUC-Mmu-064409	Mus musculus	42.31	2.00e-06	44.30
IUUC-Mac-065474	Musa acuminata	29.52	5.00e-09	54.70
IUUC-Ncr-068696	Neurospora crassa	34.25	5.00e-06	43.90
IUUC-Opr-070924	Ochotona princeps	45.83	3.00e-05	42.40
IUUC-Ont-072297	Oreochromis niloticus	45.83	4.00e-05	42.00
IUUC-Oan-073710	Ornithorhynchus anatinus	42.22	2.00e-07	48.10
IUUC-Ocu-074713	Oryctolagus cuniculus	45.83	3.00e-05	42.40
IUUC-Oba-075127	Oryza barthii	28.74	4.00e-09	55.10
IUUC-Obr-076166	Oryza brachyantha	28.07	1.00e-08	53.50
IUUC-Ogu-078514	Oryza glumaepatula	41.18	1.00e-08	53.10
IUUC-Oin-079478	Oryza indica	27.49	3.00e-08	51.20
IUUC-Olo-081036	Oryza longistaminata	37.88	5.00e-09	52.00
IUUC-Ome-081535	Oryza meridionalis	28.74	3.00e-09	55.80
IUUC-Oni-082082	Oryza nivara	41.18	1.00e-08	53.10
IUUC-Ola-087455	Oryzias latipes	46.94	1.00e-05	43.90
IUUC-Oga-088809	Otolemur garnettii	42.86	4.00e-05	42.00
IUUC-Pfo-096611	Poecilia formosa	45.83	4.00e-05	42.00
IUUC-Pab-097885	Pongo abelii	45.83	3.00e-05	42.40
IUUC-Pop-099236	Populus trichocarpa	38.10	6.00e-09	52.00
IUUC-Pgr-103450	Puccinia graminis	43.55	1.00e-06	45.10
IUUC-Ptt-103931	Puccinia triticina	36.67	2.00e-04	38.10
IUUC-Rno-104830	Rattus norvegicus	42.31	2.00e-06	44.70
IUUC-Sha-107401	Sarcophilus harrisii	45.83	4.00e-05	42.00
IUUC-Sja-107932	Schizosaccharomyces japonicus	39.62	4.00e-06	44.30
IUUC-Smo-109214	Selaginella moellendorffii	50.00	2.00e-08	50.80
IUUC-Sit-110177	Setaria italica	28.31	1.00e-09	56.60
IUUC-Sar-113238	Sorex araneus	45.83	3.00e-05	42.40
IUUC-Sbi-114401	Sorghum bicolor	42.62	6.00e-09	51.60
IUUC-Tgu-116470	Taeniopygia guttata	45.83	3.00e-05	42.40
IUUC-Tru-118054	Takifugu rubripes	45.83	3.00e-05	42.40
IUUC-Tni-120063	Tetraodon nigroviridis	45.83	3.00e-05	42.40
IUUC-Tca-121354	Theobroma cacao	39.58	2.00e-07	48.90
IUUC-Tre-121978	Trichoderma reesei	42.55	7.00e-06	43.50
IUUC-Tvi-122495	Trichoderma virens	36.49	9.00e-07	46.20
IUUC-Tae-123262	Triticum aestivum	28.48	1.00e-08	53.50
IUUC-Tur-126349	Triticum urartu	28.48	1.00e-08	53.50
IUUC-Uma-129479	Ustilago maydis	39.58	5.00e-07	48.10
IUUC-Vda-129853	Verticillium dahliae	29.49	1.00e-04	38.50
IUUC-Vpa-130662	Vicugna pacos	45.83	3.00e-05	42.40
IUUC-Vvi-131605	Vitis vinifera	43.40	4.00e-08	50.10
IUUC-Yli-134656	Yarrowia lipolytica	42.86	1.00e-06	46.20
IUUC-Zma-135233	Zea mays	28.31	7.00e-10	57.80

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence