iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033926

Ensembl Protein ID

ENSECAP00000004256.1

UniProt Accession

F6ZA94; F6ZA94_HORSE

Protein Name

Uncharacterized protein

Gene Name

TSG101

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000004362.1	ENSECAT00000006044.1	ENSECAP00000004256.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/UBC-like/UBD_UEV	4.80e-68	227.6	2	145

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/UBC-like/UBD_UEV

   S: 1    AvsesslkkvpskykdkrltvrellnliesykslkpktasfvlnDgesreLlrltGtipvpergitynipiilwlletYPekPPfvsvk 89
           Avses+lkk++skyk+++ltvre++n+i+ yk+lkp+++s+v+nDg+sreL++ltGtipvp+rg++ynipi+lwll+tYP++PP+++vk
   Q: 2    AVSESQLKKMVSKYKYRDLTVRETVNVITLYKDLKPVVDSYVFNDGSSRELMNLTGTIPVPYRGNIYNIPICLWLLDTYPYNPPICFVK 90
           89*************************************************************************************** PP
   S: 90   ekidmntikssnehvdpnGkialpvLhkWknpasnlvelvqelivllskeppklsrp 146
           ++++m tik++ +hvd+nGki+lp+Lh+Wk+p+s+l+ l+q++iv++++epp++srp
   Q: 91   PTSSM-TIKTG-KHVDANGKIYLPYLHEWKHPQSDLLGLIQVMIVVFGDEPPVFSRP 145
           *****.*****.*******************************************98 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MAVSESQLKK MVSKYKYRDL TVRETVNVIT LYKDLKPVVD SYVFNDGSSR ELMNLTGTIP 60
VPYRGNIYNI PICLWLLDTY PYNPPICFVK PTSSMTIKTG KHVDANGKIY LPYLHEWKHP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGTGCGGGG CGGCTTGGGC AGCCCGGGAG CGGCTGACCC TCTGCCTGCG GGGACGGGAG 60
TCGCGAGGCG GCCGCCATGG CGGTGTCGGA GAGCCAGCTC AAGAAAATGG TGTCCAAGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR017916--SB_dom
IPR016135--UBQ-conjugating_enzyme/RWD
IPR008883--UEV_N

PROSITE

PS51312--SB
PS51322--UEV

Pfam

PF05743--UEV
PF09454--Vps23_core

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0000813--C:ESCRT I complex
GO:0070062--C:extracellular exosome
GO:0005770--C:late endosome
GO:0005730--C:nucleolus
GO:0005886--C:plasma membrane
GO:0003714--F:transcription corepressor activity
GO:0046790--F:virion binding
GO:0007050--P:cell cycle arrest
GO:0006464--P:cellular protein modification process
GO:1990182--P:exosomal secretion
GO:0030216--P:keratinocyte differentiation
GO:0008285--P:negative regulation of cell proliferation
GO:0042059--P:negative regulation of epidermal growth factor receptor signaling pathway
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:1903543--P:positive regulation of exosomal secretion
GO:2000397--P:positive regulation of ubiquitin-dependent endocytosis
GO:1903774--P:positive regulation of viral budding via host ESCRT complex
GO:1902188--P:positive regulation of viral release from host cell
GO:0015031--P:protein transport
GO:0001558--P:regulation of cell growth
GO:1903551--P:regulation of extracellular exosome assembly
GO:0043405--P:regulation of MAP kinase activity
GO:0043162--P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO:0046755--P:viral budding

KEGG

ecb:100057099

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001072	Aegilops tauschii	26.36	7.00e-27	114.00
IUUC-Aml-002415	Ailuropoda melanoleuca	98.21	0.00e+00	726.00
IUUC-Atr-002875	Amborella trichopoda	29.78	5.00e-37	148.00
IUUC-Apl-003473	Anas platyrhynchos	87.76	0.00e+00	676.00
IUUC-Aca-004573	Anolis carolinensis	90.05	0.00e+00	663.00
IUUC-Aly-006164	Arabidopsis lyrata	37.87	2.00e-21	96.70
IUUC-Ath-006575	Arabidopsis thaliana	31.52	1.00e-32	133.00
IUUC-Ago-007755	Ashbya gossypii	24.40	1.00e-05	44.30
IUUC-Acl-008218	Aspergillus clavatus	38.76	9.00e-26	111.00
IUUC-Afl-008597	Aspergillus flavus	39.10	7.00e-26	112.00
IUUC-Afu-009017	Aspergillus fumigatus	37.98	1.00e-23	104.00
IUUC-Ani-009468	Aspergillus nidulans	38.64	2.00e-21	97.10
IUUC-Ang-009755	Aspergillus niger	36.51	6.00e-23	102.00
IUUC-Aor-010072	Aspergillus oryzae	37.59	6.00e-26	112.00
IUUC-Ate-010400	Aspergillus terreus	38.76	2.00e-25	110.00
IUUC-Ame-011620	Astyanax mexicanus	79.74	0.00e+00	633.00
IUUC-Bgr-012136	Blumeria graminis	35.04	3.00e-23	103.00
IUUC-Bta-012557	Bos taurus	97.95	0.00e+00	747.00
IUUC-Bci-013881	Botrytis cinerea	36.03	1.00e-25	110.00
IUUC-Bdi-014325	Brachypodium distachyon	31.03	7.00e-14	71.20
IUUC-Bol-016308	Brassica oleracea	40.80	5.00e-26	112.00
IUUC-Bra-017442	Brassica rapa	42.24	2.00e-23	103.00
IUUC-Cel-018697	Caenorhabditis elegans	48.84	4.00e-37	149.00
IUUC-Cja-018963	Callithrix jacchus	91.82	0.00e+00	726.00
IUUC-Cfa-020472	Canis familiaris	98.72	0.00e+00	727.00
IUUC-Cpo-022001	Cavia porcellus	98.47	0.00e+00	728.00
IUUC-Cre-022918	Chlamydomonas reinhardtii	29.89	9.00e-31	127.00
IUUC-Csa-023959	Chlorocebus sabaeus	98.46	0.00e+00	705.00
IUUC-Cho-024389	Choloepus hoffmanni	56.36	7.00e-38	151.00
IUUC-Cin-025688	Ciona intestinalis	43.77	7.00e-97	347.00
IUUC-Cne-026904	Cryptococcus neoformans	28.35	7.00e-16	78.60
IUUC-Cme-027280	Cyanidioschyzon merolae	39.09	2.00e-17	83.20
IUUC-Dre-027913	Danio rerio	80.00	4.00e-174	603.00
IUUC-Dno-029672	Dasypus novemcinctus	97.44	0.00e+00	731.00
IUUC-Dor-030175	Dipodomys ordii	97.50	6.00e-94	337.00
IUUC-Dse-031375	Dothistroma septosporum	33.33	1.00e-22	100.00
IUUC-Dme-031736	Drosophila melanogaster	47.46	9.00e-98	350.00
IUUC-Ete-032343	Echinops telfairi	92.07	0.00e+00	687.00
IUUC-Eeu-034940	Erinaceus europaeus	90.54	0.00e+00	710.00
IUUC-Fca-035491	Felis catus	97.95	0.00e+00	710.00
IUUC-Fal-037508	Ficedula albicollis	90.31	0.00e+00	674.00
IUUC-Fox-037937	Fusarium oxysporum	31.54	8.00e-21	95.10
IUUC-Fso-038091	Fusarium solani	35.29	2.00e-24	107.00
IUUC-Gmo-039427	Gadus morhua	78.72	2.00e-169	588.00
IUUC-Ggr-039724	Gaeumannomyces graminis	36.57	2.00e-24	107.00
IUUC-Gga-040998	Gallus gallus	89.29	0.00e+00	705.00
IUUC-Gac-041356	Gasterosteus aculeatus	80.15	0.00e+00	632.00
IUUC-Gma-043566	Glycine max	38.89	1.00e-24	107.00
IUUC-Ggo-044967	Gorilla gorilla	98.46	0.00e+00	705.00
IUUC-Hsa-046686	Homo sapiens	98.46	0.00e+00	705.00
IUUC-Hvu-047430	Hordeum vulgare	26.60	1.00e-26	114.00
IUUC-Itr-047929	Ictidomys tridecemlineatus	98.21	1.00e-110	392.00
IUUC-Kpa-049287	Komagataella pastoris	25.06	5.00e-27	115.00
IUUC-Lch-050597	Latimeria chalumnae	86.99	0.00e+00	701.00
IUUC-Lpe-051090	Leersia perrieri	38.02	5.00e-20	92.00
IUUC-Loc-052399	Lepisosteus oculatus	78.52	2.00e-176	611.00
IUUC-Lma-053249	Leptosphaeria maculans	28.95	6.00e-13	68.90
IUUC-Laf-053766	Loxodonta africana	98.47	0.00e+00	728.00
IUUC-Mcc-055641	Macaca mulatta	98.46	0.00e+00	705.00
IUUC-Meu-055919	Macropus eugenii	90.18	3.00e-168	584.00
IUUC-Mor-056970	Magnaporthe oryzae	37.69	2.00e-23	103.00
IUUC-Mpo-057345	Magnaporthe poae	36.15	3.00e-22	99.80
IUUC-Mtr-058436	Medicago truncatula	28.76	3.00e-32	132.00
IUUC-Mla-059037	Melampsora laricipopulina	34.93	3.00e-25	109.00
IUUC-Mga-059263	Meleagris gallopavo	88.83	0.00e+00	683.00
IUUC-Mvi-060463	Microbotryum violaceum	29.53	1.00e-16	81.60
IUUC-Mmr-060915	Microcebus murinus	97.70	0.00e+00	721.00
IUUC-Mdo-062449	Monodelphis domestica	94.37	0.00e+00	685.00
IUUC-Mmu-063151	Mus musculus	94.63	0.00e+00	698.00
IUUC-Mac-065581	Musa acuminata	36.43	1.00e-21	97.40
IUUC-Mpu-066621	Mustela putorius furo	98.21	0.00e+00	726.00
IUUC-Mlu-067336	Myotis lucifugus	97.19	0.00e+00	703.00
IUUC-Nfi-068530	Neosartorya fischeri	38.76	7.00e-24	105.00
IUUC-Ncr-068785	Neurospora crassa	35.29	4.00e-24	105.00
IUUC-Nle-069972	Nomascus leucogenys	98.46	0.00e+00	705.00
IUUC-Opr-071150	Ochotona princeps	68.03	2.00e-121	428.00
IUUC-Ont-071366	Oreochromis niloticus	81.33	0.00e+00	630.00
IUUC-Oan-073290	Ornithorhynchus anatinus	93.91	5.00e-105	373.00
IUUC-Ocu-074351	Oryctolagus cuniculus	98.21	0.00e+00	725.00
IUUC-Oba-075338	Oryza barthii	37.14	4.00e-11	62.00
IUUC-Obr-076135	Oryza brachyantha	37.19	7.00e-20	91.30
IUUC-Ogl-077182	Oryza glaberrima	36.28	8.00e-17	81.30
IUUC-Ogu-078281	Oryza glumaepatula	27.20	3.00e-20	92.40
IUUC-Oin-079068	Oryza indica	36.28	2.00e-16	80.50
IUUC-Olo-080460	Oryza longistaminata	35.80	1.00e-08	52.40
IUUC-Ome-081781	Oryza meridionalis	26.27	2.00e-17	83.60
IUUC-Oni-082517	Oryza nivara	25.99	4.00e-16	79.30
IUUC-Opu-084101	Oryza punctata	36.28	7.00e-17	81.30
IUUC-Oru-084556	Oryza rufipogon	36.28	1.00e-16	81.30
IUUC-Osa-086264	Oryza sativa	36.28	9.00e-17	81.30
IUUC-Ola-087252	Oryzias latipes	92.62	3.00e-69	253.00
IUUC-Olu-087610	Ostreococcus lucimarinus	27.25	8.00e-15	74.70
IUUC-Oga-088304	Otolemur garnettii	97.70	0.00e+00	719.00
IUUC-Oar-089734	Ovis aries	97.95	0.00e+00	747.00
IUUC-Ptr-091476	Pan troglodytes	98.46	0.00e+00	705.00
IUUC-Pan-092341	Papio anubis	98.46	0.00e+00	705.00
IUUC-Psi-093470	Pelodiscus sinensis	92.21	0.00e+00	662.00
IUUC-Pma-094143	Petromyzon marinus	64.64	2.00e-133	468.00
IUUC-Pno-095069	Phaeosphaeria nodorum	31.09	1.00e-13	71.20
IUUC-Ppa-095933	Physcomitrella patens	31.03	1.00e-38	154.00
IUUC-Pfo-096321	Poecilia formosa	82.10	2.00e-174	604.00
IUUC-Pab-098527	Pongo abelii	97.73	1.00e-180	625.00
IUUC-Pop-099323	Populus trichocarpa	26.94	4.00e-36	145.00
IUUC-Pca-101044	Procavia capensis	80.05	4.00e-157	547.00
IUUC-Ppe-101458	Prunus persica	40.83	2.00e-26	112.00
IUUC-Pva-103014	Pteropus vampyrus	88.24	2.00e-172	598.00
IUUC-Pgr-103615	Puccinia graminis	36.09	6.00e-20	92.00
IUUC-Ptt-103826	Puccinia triticina	40.20	4.00e-16	79.30
IUUC-Pte-104171	Pyrenophora teres	34.56	7.00e-21	95.50
IUUC-Pyt-104433	Pyrenophora triticirepentis	33.01	2.00e-10	60.10
IUUC-Rno-105957	Rattus norvegicus	93.61	0.00e+00	691.00
IUUC-Sce-106262	Saccharomyces cerevisiae	28.86	6.00e-10	58.50
IUUC-Sha-107607	Sarcophilus harrisii	94.84	2.00e-172	597.00
IUUC-Spo-108175	Schizosaccharomyces pombe	30.56	1.30e-02	34.30
IUUC-Ssl-108672	Sclerotinia sclerotiorum	36.03	4.00e-26	112.00
IUUC-Smo-108973	Selaginella moellendorffii	39.47	1.00e-20	94.00
IUUC-Sly-111373	Solanum lycopersicum	35.71	5.00e-23	102.00
IUUC-Stu-112844	Solanum tuberosum	35.71	1.00e-22	100.00
IUUC-Sar-113653	Sorex araneus	82.22	7.00e-178	616.00
IUUC-Sbi-114390	Sorghum bicolor	27.27	3.00e-26	112.00
IUUC-Sre-115200	Sporisorium reilianum	37.67	1.00e-23	104.00
IUUC-Ssc-115888	Sus scrofa	100.00	6.00e-114	402.00
IUUC-Tgu-117506	Taeniopygia guttata	88.83	0.00e+00	686.00
IUUC-Tru-118063	Takifugu rubripes	78.57	4.00e-169	587.00
IUUC-Tsy-118851	Tarsius syrichta	74.71	2.00e-142	498.00
IUUC-Tni-120010	Tetraodon nigroviridis	77.58	7.00e-168	583.00
IUUC-Tca-121182	Theobroma cacao	38.10	1.00e-21	97.10
IUUC-Tre-122040	Trichoderma reesei	35.38	3.00e-21	96.70
IUUC-Tvi-122660	Trichoderma virens	38.97	4.00e-25	109.00
IUUC-Tae-124561	Triticum aestivum	26.36	7.00e-27	114.00
IUUC-Tur-126651	Triticum urartu	36.59	3.00e-20	92.40
IUUC-Tme-127184	Tuber melanosporum	46.43	5.00e-25	108.00
IUUC-Tbe-127894	Tupaia belangeri	82.50	9.00e-90	323.00
IUUC-Ttr-128264	Tursiops truncatus	89.26	0.00e+00	698.00
IUUC-Uma-129407	Ustilago maydis	36.30	4.00e-24	106.00
IUUC-Vda-130002	Verticillium dahliae	30.14	2.00e-15	77.40
IUUC-Vpa-130156	Vicugna pacos	97.00	2.00e-94	338.00
IUUC-Vvi-131062	Vitis vinifera	29.10	1.00e-32	133.00
IUUC-Xtr-132332	Xenopus tropicalis	80.92	1.00e-62	231.00
IUUC-Xma-133186	Xiphophorus maculatus	81.84	9.00e-178	615.00
IUUC-Yli-134500	Yarrowia lipolytica	33.55	8.00e-13	67.80
IUUC-Zma-135391	Zea mays	36.13	2.00e-19	90.10

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence