iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Spo-108084

UUCD1 version

UUC-ScP-00017

Ensembl Protein ID

SPAC15A10.11.1:pep

UniProt Accession

O13731; UBR11_SCHPO

Genbank Protein ID

BAB84668.1; CAB10108.1

Protein Name

E3 ubiquitin-protein ligase ubr11; N-end-recognizing protein 11; RING-type E3 ubiquitin transferase ubr11

Genbank Nucleotide ID

AB079543; CU329670

Gene Name

ubr11; SPAC15A10.11

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SPAC15A10.11	SPAC15A10.11.1	SPAC15A10.11.1:pep

Annotation

mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	HINT
Protein Expression/Proteomics

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 activity/RING/RING	RING	15157887

Classification

Family	E-value	Score	Start	End
E3 activity/RING/RING	9.00e-11	40.2	1339	1474
E3 activity/N-recognin/UBR-box	1.40e-20	71.7	97	166

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkd.........................................................................gplvlp 16
           C++C+e++ d                                                                         g++v +
   Q: 1339 CLLCQEECNDqapygvigiiqgssllrktdvhseiildeiysvppnldreshsrpfgkkydtvvfnrskdrllsayppgnnirGVFVSG 1427
           888866665555555555555566666666666666666666666666666666666666666666666666666666666668***** PP
   S: 17   CgHvfhadClqkw.................pglknssskefrCPlCr 46
           CgH++h+ C++++                 +++k+s+ k+f+CPlCr
   Q: 1428 CGHLMHLGCFKNYyvarsmyrndvtaglseYYYKYSTAKFFMCPLCR 1474
           **********9999********************************8 PP

E3 activity/N-recognin/UBR-box

   S: 2    lCgrvfkvgetiyeCrtCsvdetlvlCteCfakvvHkdHeyklkksgg.ggfCdCGdteAwedgskCkkl 70
            Cg+vf+ ge iy+C++C++d+t+vlC  Cf+++ H +He+++  s+  +g+CdCGd+eAw+ + +Ck +
   Q: 97   VCGHVFRAGEVIYRCKNCGLDNTCVLCAPCFHATNHEGHETHVSISTSySGICDCGDPEAWNVDLNCKIH 166
           7****************************************99998888*******************98 PP

Organism

Schizosaccharomyces pombe

Protein Sequence
(Fasta)

MQLHDPPAPL SQPSASRLQK YLLESAEKHA YDSNEESKTH LLQEVFLSLL NYNEDNWKYF 60
LKEKPGAITS DFRLSRLQHS EPECAQELQD KRSGSKVCGH VFRAGEVIYR CKNCGLDNTC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCGCCATTT AGGTATACAA ATCAGAAATA TTAAGAAGGA ACGGTTTATA GCTGCCAAAA 60
ATATTTTTAG AGAAATTTGT TTCAACAGAA AAGTTTAAAG AAGGTAAAGG AGGATTGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003769--ClpS_core
IPR014719--Ribosomal_L7/12_C/ClpS-like
IPR011991--WHTH_DNA-bd_dom
IPR013083--Znf_RING/FYVE/PHD
IPR003126--Znf_UBR

PROSITE

PS51157--ZF_UBR

Pfam

PF02617--ClpS
PF02207--zf-UBR

SMART

SM00396--ZnF_UBR1

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0000151--C:ubiquitin ligase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0016567--P:protein ubiquitination
GO:1901718--P:regulation of dipeptide transmembrane transport by regulation of transcription from RNA polymerase II promoter
GO:0071596--P:ubiquitin-dependent protein catabolic process via the N-end rule pathway

KEGG

spo:SPAC15A10.11

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000949	Aegilops tauschii	24.05	2.00e-18	87.00
IUUC-Aml-001876	Ailuropoda melanoleuca	24.55	2.00e-33	136.00
IUUC-Atr-002501	Amborella trichopoda	23.24	2.00e-18	87.40
IUUC-Aly-005901	Arabidopsis lyrata	28.63	1.00e-16	81.60
IUUC-Ago-007752	Ashbya gossypii	21.38	1.00e-24	107.00
IUUC-Bci-013834	Botrytis cinerea	25.76	5.00e-135	474.00
IUUC-Cho-025029	Choloepus hoffmanni	24.05	1.00e-32	134.00
IUUC-Csv-026296	Ciona savignyi	26.15	9.00e-16	75.90
IUUC-Cme-027279	Cyanidioschyzon merolae	26.55	5.00e-03	33.90
IUUC-Dno-029427	Dasypus novemcinctus	26.14	3.00e-42	166.00
IUUC-Gmo-039698	Gadus morhua	24.25	1.00e-35	144.00
IUUC-Gma-043622	Glycine max	22.59	6.00e-22	99.00
IUUC-Hvu-047707	Hordeum vulgare	24.20	4.00e-17	82.40
IUUC-Loc-052818	Lepisosteus oculatus	25.31	3.00e-41	162.00
IUUC-Meu-056204	Macropus eugenii	30.92	5.00e-22	99.00
IUUC-Mtr-058538	Medicago truncatula	27.50	3.00e-16	80.10
IUUC-Mac-064773	Musa acuminata	24.16	1.00e-17	84.30
IUUC-Olo-081056	Oryza longistaminata	21.98	4.00e-13	69.70
IUUC-Ome-081738	Oryza meridionalis	21.57	2.00e-12	67.00
IUUC-Oar-089557	Ovis aries	25.84	5.00e-41	162.00
IUUC-Pma-094116	Petromyzon marinus	29.31	9.00e-27	113.00
IUUC-Pop-099496	Populus trichocarpa	22.71	7.00e-25	108.00
IUUC-Pca-100673	Procavia capensis	24.24	4.00e-32	132.00
IUUC-Ppe-101802	Prunus persica	23.39	6.00e-16	79.00
IUUC-Pva-102724	Pteropus vampyrus	25.74	5.00e-41	162.00
IUUC-Smo-108719	Selaginella moellendorffii	23.49	4.00e-23	102.00
IUUC-Sly-111701	Solanum lycopersicum	25.99	5.00e-21	95.90
IUUC-Sbi-114577	Sorghum bicolor	23.23	2.00e-19	90.50
IUUC-Tsy-119032	Tarsius syrichta	23.27	3.00e-35	142.00
IUUC-Tca-121077	Theobroma cacao	21.29	2.00e-18	87.40
IUUC-Tae-125783	Triticum aestivum	24.79	1.00e-21	97.40
IUUC-Tur-126562	Triticum urartu	22.64	7.00e-16	78.20
IUUC-Zma-135553	Zea mays	38.60	2.00e-11	63.90

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence