iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mtr-057633

Ensembl Protein ID

AES98293

UniProt Accession

G7JYH3; G7JYH3_MEDTR

Genbank Protein ID

AES98293.1

Protein Name

E3 ubiquitin-protein ligase UPL1-like protein

Genbank Nucleotide ID

CM001221

Gene Name

MTR_5g066710

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MTR_5g066710	AES98293	AES98293

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	3.60e-121	406.1	3316	3654
UBD/Alpha-Helix/UBA	2.00e-06	29.2	1305	1344

Active Site

Position(s)	Description	Evidence
3622	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfyklll 101
           +dlk rl v+f+gEeg+d+gG+tre+++lls+ ++++ + lf+ + ++++t+qpnp+s ++ +ehl++F+f+Gr++gkal+dg+lld+++++sfyk++l
   Q: 3316 QDLKGRLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFT-TVGNESTFQPNPNSVYQ-TEHLSYFKFIGRVVGKALFDGQLLDVHFTRSFYKHIL 3412
           799***********************************99995.55577788******986.5************************************ PP
   S: 102  gkklsledleevdpelykslkeikenaesdieelgldltfsvseei.......lgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveaf 193
           g+k++++d+e++dp+++k+lk+++en   di++  ldltfs++ ++         e++++eL+pgG+ni+Vt+eNk++Yv+lv+e+rl++ i+ q++af
   Q: 3413 GVKVTYHDIEAIDPDYFKNLKWMLEN---DISDV-LDLTFSIDADEeklilyeRTEVTDYELIPGGRNIKVTEENKHQYVDLVAEHRLTTAIRPQINAF 3507
           ************************99...99998.99999977777779996666777888************************************** PP
   S: 194  reGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelk....prlfv 288
            eGf+e+ip el+s+F+ +elelli+G ++id++dl+++t+y +gy++ sp+iqwFwev++++s+e+++++LqFvTg+s++Pl+Gf +l+     ++f+
   Q: 3508 LEGFSELIPRELISIFNDKELELLISGLPDIDLDDLRANTEY-SGYSAASPVIQWFWEVVQGLSKEDKARLLQFVTGTSKVPLEGFSALQgisgSQKFQ 3605
           ******************************************.55*************************************************9**** PP
   S: 289  irk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFel 335
           i+k ++s+d+lPs++TCfn+L+LPeY+sk+ l+e+Ll+Ai+e+ +gF++
   Q: 3606 IHKaYGSPDHLPSAHTCFNQLDLPEYPSKQHLEERLLLAIHEAsEGFGF 3654
           ***999*************************************9***85 PP

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
           +e  +  +veMGF+r++a +aLr   +n++e ++e+L+++
   Q: 1305 NETTISTIVEMGFSRSRAEEALRHVgSNSVELVMEWLFSH 1344
           788999********************************97 PP

Organism

Medicago truncatula

Protein Sequence
(Fasta)

MTTLRSNWPS RLRQLLSSEG AIGPSIKLDS EPPPKVKAFI EKVIQCPLQD IAIPLSGFRW 60
EYDKGNFHHW RPLLLHFDTY FKTYLSCRND LTLLDNLEVD SPLPKHDILQ ILRVMQIILE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTGGGAGAG AAGACCCCCG CTCTAGAAGC AACAGAGTTA AGTAACCATT TCTCTAATTC 60
TCAGTATACT CACACTATAT ATTCTCATCT CCCTCACACT ATTCCCAATT TTTTTTTTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR025527--DUF4414
IPR010309--E3_Ub_ligase_DUF908
IPR010314--E3_Ub_ligase_DUF913
IPR000569--HECT_dom
IPR015940--UBA
IPR009060--UBA-like
IPR003903--UIM_dom

PROSITE

PS50237--HECT
PS50030--UBA
PS50330--UIM

Pfam

PF14377--DUF4414
PF06012--DUF908
PF06025--DUF913
PF00632--HECT
PF00627--UBA

SMART

SM00119--HECTc
SM00165--UBA

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

KEGG

mtr:MTR_5g066710

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000627	Aegilops tauschii	57.20	0.00e+00	2133.00
IUUC-Atr-002582	Amborella trichopoda	61.87	0.00e+00	3997.00
IUUC-Apl-003400	Anas platyrhynchos	42.34	6.00e-101	360.00
IUUC-Aly-006157	Arabidopsis lyrata	67.08	0.00e+00	4416.00
IUUC-Acl-008254	Aspergillus clavatus	41.20	1.00e-140	495.00
IUUC-Afl-008712	Aspergillus flavus	33.25	1.00e-157	550.00
IUUC-Afu-009022	Aspergillus fumigatus	39.83	2.00e-140	494.00
IUUC-Ani-009412	Aspergillus nidulans	33.90	2.00e-156	548.00
IUUC-Ang-009771	Aspergillus niger	32.37	7.00e-155	543.00
IUUC-Aor-010186	Aspergillus oryzae	37.98	1.00e-131	464.00
IUUC-Bgr-012043	Blumeria graminis	32.89	1.00e-147	519.00
IUUC-Bci-013995	Botrytis cinerea	39.32	1.00e-142	502.00
IUUC-Bdi-014884	Brachypodium distachyon	58.31	0.00e+00	2232.00
IUUC-Bol-015228	Brassica oleracea	65.82	0.00e+00	2241.00
IUUC-Bra-016726	Brassica rapa	64.60	0.00e+00	2345.00
IUUC-Cpo-021766	Cavia porcellus	44.55	9.00e-103	367.00
IUUC-Cre-022900	Chlamydomonas reinhardtii	61.72	6.00e-160	556.00
IUUC-Cme-027267	Cyanidioschyzon merolae	52.73	8.00e-128	451.00
IUUC-Dse-031197	Dothistroma septosporum	32.93	8.00e-144	506.00
IUUC-Ete-032966	Echinops telfairi	44.32	1.00e-102	367.00
IUUC-Fal-036687	Ficedula albicollis	42.34	3.00e-101	362.00
IUUC-Fox-037756	Fusarium oxysporum	33.50	6.00e-158	553.00
IUUC-Fso-038464	Fusarium solani	32.91	1.00e-153	538.00
IUUC-Ggr-039946	Gaeumannomyces graminis	31.57	2.00e-138	488.00
IUUC-Gga-040845	Gallus gallus	42.34	2.00e-101	363.00
IUUC-Gma-043129	Glycine max	85.67	0.00e+00	5872.00
IUUC-Ggo-044465	Gorilla gorilla	44.22	3.00e-101	362.00
IUUC-Hvu-047697	Hordeum vulgare	57.43	0.00e+00	2176.00
IUUC-Lpe-051550	Leersia perrieri	58.00	0.00e+00	2175.00
IUUC-Lma-053159	Leptosphaeria maculans	32.52	3.00e-150	527.00
IUUC-Meu-056751	Macropus eugenii	44.85	2.00e-77	284.00
IUUC-Mor-057201	Magnaporthe oryzae	32.65	2.00e-145	511.00
IUUC-Mga-059935	Meleagris gallopavo	42.34	3.00e-101	362.00
IUUC-Mac-065499	Musa acuminata	60.77	0.00e+00	2357.00
IUUC-Nfi-068278	Neosartorya fischeri	33.14	8.00e-157	549.00
IUUC-Ncr-068813	Neurospora crassa	41.27	7.00e-145	509.00
IUUC-Oba-075757	Oryza barthii	58.74	0.00e+00	2136.00
IUUC-Obr-076553	Oryza brachyantha	58.91	0.00e+00	2217.00
IUUC-Ogl-077520	Oryza glaberrima	58.99	0.00e+00	2246.00
IUUC-Ogu-078278	Oryza glumaepatula	58.95	0.00e+00	2243.00
IUUC-Oin-079767	Oryza indica	58.56	0.00e+00	2229.00
IUUC-Olo-080380	Oryza longistaminata	58.38	0.00e+00	2234.00
IUUC-Ome-081925	Oryza meridionalis	59.04	0.00e+00	2240.00
IUUC-Oni-082619	Oryza nivara	58.93	0.00e+00	2241.00
IUUC-Opu-083684	Oryza punctata	58.84	0.00e+00	2237.00
IUUC-Oru-084501	Oryza rufipogon	59.04	0.00e+00	2251.00
IUUC-Osa-086251	Oryza sativa	71.65	0.00e+00	1117.00
IUUC-Ola-086777	Oryzias latipes	42.98	5.00e-104	372.00
IUUC-Ptr-090529	Pan troglodytes	44.32	2.00e-102	366.00
IUUC-Psi-093969	Pelodiscus sinensis	42.55	2.00e-102	366.00
IUUC-Pma-094364	Petromyzon marinus	46.17	1.00e-89	322.00
IUUC-Pno-094871	Phaeosphaeria nodorum	32.35	1.00e-146	515.00
IUUC-Pop-099468	Populus trichocarpa	72.06	0.00e+00	4879.00
IUUC-Pca-100568	Procavia capensis	45.41	2.00e-88	320.00
IUUC-Ppe-101641	Prunus persica	73.84	0.00e+00	4959.00
IUUC-Pgr-103465	Puccinia graminis	36.31	2.00e-127	451.00
IUUC-Ptt-103813	Puccinia triticina	34.63	5.00e-118	420.00
IUUC-Pte-104018	Pyrenophora teres	32.53	8.00e-152	532.00
IUUC-Pyt-104713	Pyrenophora triticirepentis	33.06	2.00e-152	535.00
IUUC-Rno-105153	Rattus norvegicus	44.32	8.00e-103	367.00
IUUC-Sja-107814	Schizosaccharomyces japonicus	39.31	1.00e-132	468.00
IUUC-Sit-110598	Setaria italica	58.10	0.00e+00	2164.00
IUUC-Sly-111706	Solanum lycopersicum	67.19	0.00e+00	4491.00
IUUC-Sbi-114042	Sorghum bicolor	57.30	0.00e+00	2145.00
IUUC-Sre-114958	Sporisorium reilianum	51.43	5.00e-143	500.00
IUUC-Tgu-117225	Taeniopygia guttata	42.13	3.00e-101	362.00
IUUC-Tsy-119407	Tarsius syrichta	51.34	1.00e-96	347.00
IUUC-Tca-121479	Theobroma cacao	73.90	0.00e+00	5031.00
IUUC-Tre-121909	Trichoderma reesei	32.77	9.00e-153	535.00
IUUC-Tae-125214	Triticum aestivum	61.87	0.00e+00	1619.00
IUUC-Tme-127172	Tuber melanosporum	39.97	2.00e-138	488.00
IUUC-Uma-129355	Ustilago maydis	51.02	4.00e-145	507.00
IUUC-Vvi-131078	Vitis vinifera	74.16	0.00e+00	4623.00
IUUC-Yli-134657	Yarrowia lipolytica	31.88	7.00e-146	512.00
IUUC-Zma-135570	Zea mays	58.77	0.00e+00	3713.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence