iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Spo-108375

Ensembl Protein ID

SPAC16E8.01.1:pep

UniProt Accession

O13736; SLA1_SCHPO

Genbank Protein ID

CAB11030.1

Protein Name

Actin cytoskeleton-regulatory complex protein sla1

Genbank Nucleotide ID

CU329670

Gene Name

shd1; sla1; SPAC16E8.01

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SPAC16E8.01	SPAC16E8.01.1	SPAC16E8.01.1:pep

Annotation

mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	HINT
Post-translational Modifications (PTMs)
dbPAF	dbPTM	UniProt
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.00e-24	84.4	512	564

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
              vlyd+ a+  deLt k+   v ++ +++ + +W+k+     gk+G++P+nF++
   Q: 512  MGTVLYDFIAEAADELTVKANMRVVIV-NDTASSDWWKC--SVDGKEGVVPSNFIK 564
           5689****************9999999.99*********..8************98 PP

Organism

Schizosaccharomyces pombe

Functional Description
(View)

Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity).

Protein Sequence
(Fasta)

MANLPIIGIY KVLYSYEPQE INPGEEIPEN EREISIVEDE IVCLLEKGED DWYLVKRNVN 60
SNDDDEEIGI VPSNYITEAE PSTKMKALYD YTQQSVDEIS FQADQTLDCY GDTDSDWILV 120

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Nucleotide Sequence
(Fasta)

GGTAAAGCCA CCTTGGCTAC ATCGTTTATC AACTCAGACT GTACAACCTA CATTTGTCGC 60
CATGGCAAAT TTACCTATAA TAGGCATCTA TAAGGTGCTG TACAGTTATG AACCGCAAGA 120

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Sequence Source

Ensembl

Keyword

KW-0009--Actin-binding
KW-1003--Cell membrane
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0254--Endocytosis
KW-0967--Endosome
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0728--SH3 domain

Interpro

IPR013182--DUF1720
IPR011993--PH_dom-like
IPR013761--SAM/pointed
IPR001452--SH3_domain
IPR007131--SHD1
IPR029922--Sla1

PROSITE

PS50002--SH3

Pfam

PF08226--DUF1720
PF00018--SH3_1
PF14604--SH3_9
PF03983--SHD1

SMART

SM00326--SH3

Gene Ontology

GO:0030479--C:actin cortical patch
GO:0032153--C:cell division site
GO:0051286--C:cell tip
GO:0005829--C:cytosol
GO:0010008--C:endosome membrane
GO:0005643--C:nuclear pore
GO:0005886--C:plasma membrane
GO:0000147--P:actin cortical patch assembly
GO:0007015--P:actin filament organization
GO:0006897--P:endocytosis

KEGG

spo:SPAC16E8.01

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001208	Ailuropoda melanoleuca	41.82	2.00e-08	52.80
IUUC-Aca-004548	Anolis carolinensis	40.00	5.00e-07	48.10
IUUC-Ago-007979	Ashbya gossypii	28.13	3.00e-37	148.00
IUUC-Acl-008300	Aspergillus clavatus	30.55	3.00e-54	205.00
IUUC-Afl-008694	Aspergillus flavus	40.73	2.00e-43	169.00
IUUC-Afu-008881	Aspergillus fumigatus	31.06	5.00e-36	144.00
IUUC-Ani-009274	Aspergillus nidulans	28.77	1.00e-42	166.00
IUUC-Ang-009534	Aspergillus niger	32.36	1.00e-63	236.00
IUUC-Aor-010097	Aspergillus oryzae	32.35	8.00e-53	200.00
IUUC-Ate-010495	Aspergillus terreus	32.87	3.00e-31	129.00
IUUC-Bgr-012294	Blumeria graminis	28.96	5.00e-57	214.00
IUUC-Bci-013990	Botrytis cinerea	33.62	3.00e-33	135.00
IUUC-Cja-018921	Callithrix jacchus	41.82	2.00e-08	53.10
IUUC-Cfa-020772	Canis familiaris	41.82	2.00e-08	52.80
IUUC-Cpo-022455	Cavia porcellus	41.82	2.00e-08	52.80
IUUC-Csa-023660	Chlorocebus sabaeus	41.82	1.00e-08	53.50
IUUC-Csv-025910	Ciona savignyi	41.67	4.00e-07	44.70
IUUC-Cgl-026697	Colletotrichum gloeosporioides	31.41	5.00e-39	154.00
IUUC-Cne-026842	Cryptococcus neoformans	34.40	2.00e-30	126.00
IUUC-Dre-028389	Danio rerio	40.00	6.00e-08	51.20
IUUC-Dno-028907	Dasypus novemcinctus	41.82	2.00e-08	53.10
IUUC-Dor-030300	Dipodomys ordii	41.82	2.00e-08	52.80
IUUC-Dse-031496	Dothistroma septosporum	31.89	3.00e-31	129.00
IUUC-Ete-032641	Echinops telfairi	41.82	2.00e-08	52.40
IUUC-Eca-033297	Equus caballus	41.82	2.00e-08	53.10
IUUC-Eeu-035356	Erinaceus europaeus	41.82	2.00e-08	53.10
IUUC-Fca-036302	Felis catus	41.82	2.00e-08	52.80
IUUC-Fso-038358	Fusarium solani	30.33	1.00e-50	193.00
IUUC-Ggr-040032	Gaeumannomyces graminis	37.04	2.00e-20	92.80
IUUC-Ggo-045534	Gorilla gorilla	41.82	2.00e-08	52.80
IUUC-Hsa-046672	Homo sapiens	41.82	2.00e-08	53.10
IUUC-Itr-048045	Ictidomys tridecemlineatus	41.82	2.00e-08	52.80
IUUC-Kpa-049118	Komagataella pastoris	33.33	1.00e-39	156.00
IUUC-Loc-052010	Lepisosteus oculatus	41.82	2.00e-08	53.10
IUUC-Lma-053174	Leptosphaeria maculans	39.42	4.00e-22	96.30
IUUC-Laf-053978	Loxodonta africana	41.82	2.00e-08	52.80
IUUC-Mcc-055551	Macaca mulatta	41.82	2.00e-08	53.10
IUUC-Mor-056954	Magnaporthe oryzae	35.56	2.00e-18	86.30
IUUC-Mpo-057576	Magnaporthe poae	30.12	3.00e-34	139.00
IUUC-Mla-059035	Melampsora laricipopulina	51.72	3.00e-17	82.40
IUUC-Mga-060136	Meleagris gallopavo	40.00	3.00e-07	48.50
IUUC-Mvi-060454	Microbotryum violaceum	48.53	2.00e-17	83.20
IUUC-Mmr-061269	Microcebus murinus	41.82	2.00e-08	52.80
IUUC-Mmu-063741	Mus musculus	41.82	2.00e-08	52.80
IUUC-Mpu-066694	Mustela putorius furo	41.82	2.00e-08	52.80
IUUC-Mlu-067377	Myotis lucifugus	41.82	2.00e-08	53.10
IUUC-Nfi-068406	Neosartorya fischeri	29.24	4.00e-48	185.00
IUUC-Ncr-068902	Neurospora crassa	36.96	5.00e-22	98.20
IUUC-Nle-069243	Nomascus leucogenys	41.82	1.00e-08	53.10
IUUC-Opr-070611	Ochotona princeps	41.82	2.00e-08	52.80
IUUC-Oan-073477	Ornithorhynchus anatinus	41.82	3.00e-09	52.40
IUUC-Ocu-074436	Oryctolagus cuniculus	41.82	2.00e-08	52.80
IUUC-Ola-086487	Oryzias latipes	41.82	2.00e-08	52.80
IUUC-Oga-088966	Otolemur garnettii	41.82	2.00e-08	52.80
IUUC-Ptr-090896	Pan troglodytes	41.82	2.00e-08	53.10
IUUC-Pan-092021	Papio anubis	41.82	1.00e-08	53.10
IUUC-Pno-094774	Phaeosphaeria nodorum	32.98	2.00e-39	156.00
IUUC-Pfo-097206	Poecilia formosa	39.29	2.00e-08	52.80
IUUC-Pca-100841	Procavia capensis	41.82	2.00e-08	52.80
IUUC-Pva-102291	Pteropus vampyrus	39.71	3.00e-09	54.70
IUUC-Pgr-103396	Puccinia graminis	46.15	6.00e-17	81.60
IUUC-Ptt-103751	Puccinia triticina	46.58	1.00e-17	84.00
IUUC-Pte-104349	Pyrenophora teres	42.75	4.00e-27	115.00
IUUC-Pyt-104695	Pyrenophora triticirepentis	33.07	3.00e-35	142.00
IUUC-Rno-105602	Rattus norvegicus	40.58	1.00e-09	56.60
IUUC-Sce-106372	Saccharomyces cerevisiae	29.56	8.00e-39	154.00
IUUC-Sja-107962	Schizosaccharomyces japonicus	38.84	2.00e-119	421.00
IUUC-Ssl-108553	Sclerotinia sclerotiorum	37.00	3.00e-26	112.00
IUUC-Stu-112750	Solanum tuberosum	34.15	5.80e-01	27.70
IUUC-Sbi-113862	Sorghum bicolor	52.63	7.00e-01	25.80
IUUC-Sre-115072	Sporisorium reilianum	58.46	4.00e-17	82.00
IUUC-Ssc-116113	Sus scrofa	41.82	2.00e-08	53.10
IUUC-Tgu-117420	Taeniopygia guttata	40.00	4.00e-07	48.50
IUUC-Tca-121147	Theobroma cacao	36.59	1.00e-01	27.70
IUUC-Tre-121912	Trichoderma reesei	33.33	3.00e-41	162.00
IUUC-Tvi-122336	Trichoderma virens	35.11	2.00e-19	89.70
IUUC-Tme-127017	Tuber melanosporum	29.91	3.00e-28	119.00
IUUC-Ttr-128533	Tursiops truncatus	41.82	2.00e-08	52.80
IUUC-Uma-129502	Ustilago maydis	59.70	1.00e-17	84.00
IUUC-Vda-129879	Verticillium dahliae	28.57	4.00e-55	208.00
IUUC-Xma-133746	Xiphophorus maculatus	41.82	2.00e-08	52.80
IUUC-Yli-134528	Yarrowia lipolytica	33.94	2.00e-28	119.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence