iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-069087

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01103689

Gene Name

PAFAH1B1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000017217.2	ENSNLET00000021957.2	ENSNLEP00000020907.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.30e-45	150.0	190	229
UBD/Beta-Prp	5.20e-73	245.8	107	339

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH   v+++a  ++ +++vs+s+D+tik+W++ tg ++k+
   Q: 190  GHDHNVSSVAImPNgDHIVSASRDKTIKMWEVQTGYCVKT 229
           899*******99777********************99875 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsv 97
           h s++t v f+p  s+++++s+d+tikvwd++tg++ r+l+gh++ v++++f+++gk+l+++s D+tik+wd++ ++c++t++gh+++v
   Q: 107  HRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNV 195
           5668888********************************************************************************** PP
   S: 98   lslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvysl 186
            s++++p+gd++vs+s+d+ti++w+++tg+c++ t++gh+++v++v+ ++dg l++s+s+D+tvr+W ++t+++  +l++ h++ v+++
   Q: 196  SSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVK-TFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELRE-HEHVVECI 282
           *********************************.*********************************************9.******** PP
   S: 187  sfdsng....................kelvsgsldgtvklwdlqtgecvrtlnghtd 223
           s+ +++                    ++l+sgs+d+t+k+wd++tg c++tl+  ++
   Q: 283  SWAPESsyssiseatgsetkksgkpgPFLLSGSRDKTIKMWDVSTGMCLMTLISTRR 339
           ***************************************************998765 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MVLSQRQRDE LNRAIADYLR SNGYEEAYSV FKKEAELDMN EELDKKYAGL LEKKWTSVIR 60
LQKKVMELES KLNEAKEEFT SGGPLGQKRD PKEWIPRPPE KYALSGHRSP VTRVIFHPVF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGGAATGAA TCTTACTTGT TGAATATCTT CTGGTTACTA GTTGGATTCA TTTGTGAAAG 60
AATCATTTTC CCCTGTGTGG AAGACACTTA GTGGCATATT TAAATTATAA GTCCACGGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0493--Microtubule
KW-0498--Mitosis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR017252--Dynein_regulator_LIS1
IPR020472--G-protein_beta_WD-40_rep
IPR006594--LisH
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50896--LISH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08513--LisH
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00667--LisH
SM00320--WD40

Gene Ontology

GO:0000235--C:astral microtubule
GO:0005938--C:cell cortex
GO:0005813--C:centrosome
GO:0070062--C:extracellular exosome
GO:0000776--C:kinetochore
GO:0005875--C:microtubule associated complex
GO:0005635--C:nuclear envelope
GO:0008344--P:adult locomotory behavior
GO:0048854--P:brain morphogenesis
GO:0051301--P:cell division
GO:0021987--P:cerebral cortex development
GO:0021540--P:corpus callosum morphogenesis
GO:0000132--P:establishment of mitotic spindle orientation
GO:0031023--P:microtubule organizing center organization
GO:0007067--P:mitotic nuclear division
GO:0050885--P:neuromuscular process controlling balance
GO:0001764--P:neuron migration
GO:0006810--P:transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001589	Ailuropoda melanoleuca	99.69	0.00e+00	676.00
IUUC-Apl-004024	Anas platyrhynchos	98.51	0.00e+00	693.00
IUUC-Aca-004564	Anolis carolinensis	97.91	0.00e+00	686.00
IUUC-Ago-007862	Ashbya gossypii	28.21	2.00e-32	133.00
IUUC-Acl-008360	Aspergillus clavatus	44.73	3.00e-85	308.00
IUUC-Afl-008502	Aspergillus flavus	42.90	1.00e-73	270.00
IUUC-Afu-008848	Aspergillus fumigatus	45.51	6.00e-88	317.00
IUUC-Ani-009173	Aspergillus nidulans	40.52	2.00e-71	263.00
IUUC-Ang-009873	Aspergillus niger	41.69	4.00e-73	268.00
IUUC-Aor-009973	Aspergillus oryzae	40.99	2.00e-71	262.00
IUUC-Ate-010523	Aspergillus terreus	40.12	4.00e-72	265.00
IUUC-Ame-010969	Astyanax mexicanus	94.93	0.00e+00	669.00
IUUC-Bgr-011972	Blumeria graminis	47.06	1.00e-87	317.00
IUUC-Bta-013106	Bos taurus	99.70	0.00e+00	697.00
IUUC-Bci-013615	Botrytis cinerea	44.03	2.00e-79	289.00
IUUC-Cel-018459	Caenorhabditis elegans	56.38	4.00e-116	410.00
IUUC-Cja-018755	Callithrix jacchus	96.72	0.00e+00	678.00
IUUC-Cfa-020749	Canis familiaris	99.70	0.00e+00	697.00
IUUC-Cpo-022371	Cavia porcellus	99.70	0.00e+00	697.00
IUUC-Csa-023524	Chlorocebus sabaeus	98.89	4.00e-162	563.00
IUUC-Cho-024764	Choloepus hoffmanni	77.87	5.00e-155	540.00
IUUC-Cin-025753	Ciona intestinalis	71.43	7.00e-145	506.00
IUUC-Csv-025817	Ciona savignyi	69.25	1.00e-147	515.00
IUUC-Cgl-026529	Colletotrichum gloeosporioides	45.96	1.00e-78	286.00
IUUC-Cne-027087	Cryptococcus neoformans	52.03	5.00e-85	308.00
IUUC-Dre-027554	Danio rerio	95.22	0.00e+00	668.00
IUUC-Dno-029050	Dasypus novemcinctus	99.40	0.00e+00	697.00
IUUC-Dor-030222	Dipodomys ordii	81.40	0.00e+00	632.00
IUUC-Dse-031164	Dothistroma septosporum	42.50	8.00e-82	297.00
IUUC-Dme-031745	Drosophila melanogaster	69.25	8.00e-134	469.00
IUUC-Ete-032508	Echinops telfairi	99.01	5.00e-121	427.00
IUUC-Eca-034288	Equus caballus	99.07	0.00e+00	672.00
IUUC-Eeu-034984	Erinaceus europaeus	81.40	0.00e+00	632.00
IUUC-Fca-036498	Felis catus	99.70	0.00e+00	697.00
IUUC-Fal-036920	Ficedula albicollis	98.51	0.00e+00	693.00
IUUC-Fox-037996	Fusarium oxysporum	44.51	3.00e-83	302.00
IUUC-Fso-038160	Fusarium solani	43.79	3.00e-78	285.00
IUUC-Gmo-038983	Gadus morhua	94.33	0.00e+00	664.00
IUUC-Ggr-040051	Gaeumannomyces graminis	44.07	5.00e-79	288.00
IUUC-Gga-040623	Gallus gallus	98.51	0.00e+00	693.00
IUUC-Gac-041613	Gasterosteus aculeatus	92.84	0.00e+00	657.00
IUUC-Ggo-045410	Gorilla gorilla	88.58	1.00e-167	582.00
IUUC-Hsa-046358	Homo sapiens	99.40	0.00e+00	696.00
IUUC-Itr-047890	Ictidomys tridecemlineatus	99.70	0.00e+00	697.00
IUUC-Kpa-049351	Komagataella pastoris	30.54	2.00e-36	146.00
IUUC-Lch-049936	Latimeria chalumnae	97.31	0.00e+00	682.00
IUUC-Loc-052476	Lepisosteus oculatus	96.30	0.00e+00	654.00
IUUC-Lma-053170	Leptosphaeria maculans	45.38	1.00e-81	296.00
IUUC-Laf-053713	Loxodonta africana	97.60	0.00e+00	680.00
IUUC-Mcc-054628	Macaca mulatta	99.10	0.00e+00	695.00
IUUC-Meu-055927	Macropus eugenii	80.69	2.00e-92	331.00
IUUC-Mor-056962	Magnaporthe oryzae	43.79	5.00e-79	288.00
IUUC-Mpo-057583	Magnaporthe poae	44.29	3.00e-75	275.00
IUUC-Mla-058819	Melampsora laricipopulina	51.30	3.00e-96	345.00
IUUC-Mga-059945	Meleagris gallopavo	98.21	0.00e+00	692.00
IUUC-Mvi-060403	Microbotryum violaceum	51.76	1.00e-105	376.00
IUUC-Mmr-061289	Microcebus murinus	99.69	0.00e+00	676.00
IUUC-Mdo-061912	Monodelphis domestica	98.81	0.00e+00	690.00
IUUC-Mmu-063253	Mus musculus	99.70	0.00e+00	697.00
IUUC-Mpu-066638	Mustela putorius furo	99.70	0.00e+00	697.00
IUUC-Mlu-067267	Myotis lucifugus	97.60	0.00e+00	680.00
IUUC-Nfi-068571	Neosartorya fischeri	43.63	3.00e-80	292.00
IUUC-Ncr-068895	Neurospora crassa	46.82	2.00e-85	309.00
IUUC-Opr-070579	Ochotona princeps	99.40	0.00e+00	697.00
IUUC-Ont-072432	Oreochromis niloticus	95.22	0.00e+00	671.00
IUUC-Oan-073072	Ornithorhynchus anatinus	99.70	0.00e+00	697.00
IUUC-Ocu-074180	Oryctolagus cuniculus	99.40	0.00e+00	697.00
IUUC-Ola-086772	Oryzias latipes	94.63	0.00e+00	663.00
IUUC-Oga-088219	Otolemur garnettii	97.01	0.00e+00	677.00
IUUC-Oar-090394	Ovis aries	99.70	0.00e+00	697.00
IUUC-Ptr-091517	Pan troglodytes	99.70	0.00e+00	697.00
IUUC-Pan-092421	Papio anubis	99.10	0.00e+00	695.00
IUUC-Psi-093370	Pelodiscus sinensis	98.51	0.00e+00	693.00
IUUC-Pma-094319	Petromyzon marinus	87.59	3.00e-141	494.00
IUUC-Pno-094815	Phaeosphaeria nodorum	46.48	3.00e-85	308.00
IUUC-Pfo-097089	Poecilia formosa	94.33	0.00e+00	664.00
IUUC-Pab-098421	Pongo abelii	99.70	0.00e+00	697.00
IUUC-Pca-100120	Procavia capensis	82.93	6.00e-157	546.00
IUUC-Pva-102960	Pteropus vampyrus	99.40	0.00e+00	693.00
IUUC-Pgr-103538	Puccinia graminis	50.29	6.00e-96	344.00
IUUC-Ptt-103990	Puccinia triticina	42.46	3.00e-45	176.00
IUUC-Pte-104261	Pyrenophora teres	47.04	2.00e-85	309.00
IUUC-Pyt-104780	Pyrenophora triticirepentis	47.32	1.00e-85	310.00
IUUC-Rno-105123	Rattus norvegicus	99.70	0.00e+00	697.00
IUUC-Sha-107010	Sarcophilus harrisii	98.51	0.00e+00	689.00
IUUC-Sja-107899	Schizosaccharomyces japonicus	33.71	1.00e-51	197.00
IUUC-Ssl-108571	Sclerotinia sclerotiorum	43.91	1.00e-79	290.00
IUUC-Sar-113309	Sorex araneus	98.77	0.00e+00	666.00
IUUC-Sre-115003	Sporisorium reilianum	51.76	5.00e-103	367.00
IUUC-Ssc-116148	Sus scrofa	99.70	0.00e+00	697.00
IUUC-Tgu-117299	Taeniopygia guttata	98.21	0.00e+00	691.00
IUUC-Tru-118179	Takifugu rubripes	91.94	0.00e+00	657.00
IUUC-Tsy-119493	Tarsius syrichta	97.91	0.00e+00	681.00
IUUC-Tni-120355	Tetraodon nigroviridis	93.13	0.00e+00	632.00
IUUC-Tre-121977	Trichoderma reesei	43.29	1.00e-77	283.00
IUUC-Tvi-122661	Trichoderma virens	44.94	7.00e-78	284.00
IUUC-Tme-127031	Tuber melanosporum	47.14	5.00e-85	308.00
IUUC-Tbe-127492	Tupaia belangeri	77.72	3.00e-78	285.00
IUUC-Ttr-128929	Tursiops truncatus	99.40	0.00e+00	696.00
IUUC-Uma-129347	Ustilago maydis	50.15	2.00e-100	358.00
IUUC-Vda-129837	Verticillium dahliae	45.04	7.00e-82	297.00
IUUC-Vpa-130532	Vicugna pacos	75.71	2.00e-165	575.00
IUUC-Xtr-131985	Xenopus tropicalis	97.91	0.00e+00	690.00
IUUC-Xma-133314	Xiphophorus maculatus	94.63	0.00e+00	665.00
IUUC-Yli-134403	Yarrowia lipolytica	36.71	4.00e-52	198.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence