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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Dme-031827
Ensembl Protein ID FBpp0074742
UniProt Accession Q9VW09; Q8T3L4; LTN1_DROME
Genbank Protein ID AAF49146.2; AAM11308.1
Protein Name E3 ubiquitin-protein ligase listerin; RING-type E3 ubiquitin transferase listerin
Genbank Nucleotide ID AE014296; AY094955
Gene Name l(3)76BDr; CG32210
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
FBgn0262517 FBtr0074974 FBpp0074742
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
microRNA
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAFdbPTMUniProt
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/RING/RING 30.48 6.00e-69 261.00 IUUC-Hsa-047016
E3 activity/RING/RING 32.46 2.00e-71 269.00 IUUC-Mmu-064389
E3 activity/RING/RING 30.69 6.00e-24 108.00 IUUC-Sce-106305
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Drosophila melanogaster
Functional Description
(View)

Functional Description


     E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. Ubiquitination leads to TER94/VCP recruitment for extraction and degradation of the incomplete translation product.
 E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. Ubiquitination leads to TER94/VCP recruitment for extraction and degradation of the incomplete translation product.
Protein Sequence
(Fasta)
MGGKTKQAPR TKNNAKPSSS SRTAELLGSS TPIFVGFSAQ TDGGGLVPFA PGFASAEQMP 60
DSFDAAISPQ TQIILRKLSK KDPMTKKKAL QELHELIEQS DVEVLKNILP LWPKYYLNLA 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dme-031827|E3,RING|Drosophila melanogaster
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Nucleotide Sequence
(Fasta)
AGAGACAGAA GAAGAAGAGA GAAATGGGTG GAAAGACAAA ACAAGCGCCG CGCACCAAAA 60
ATAATGCCAA GGTAAGGCGT AGTAAGGTAT TAATATGTTA TTTAACCGTG CCCTCGACCC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dme-031827|E3,RING|Drosophila melanogaster
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR011030--Vitellinogen_superhlx
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS50089--ZF_RING_2
Gene Ontology

GO:0016740--F:transferase activity
GO:0008270--F:zinc ion binding
GO:0016567--P:protein ubiquitination
GO:1990116--P:ribosome-associated ubiquitin-dependent protein catabolic process
GO:0030431--P:sleep
KEGG dme:Dmel_CG32210
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000717 Aegilops tauschii 40.67 1.00e-38 155.00
IUUC-Aml-002311 Ailuropoda melanoleuca 32.48 7.00e-69 255.00
IUUC-Atr-002905 Amborella trichopoda 42.36 2.00e-39 158.00
IUUC-Apl-003323 Anas platyrhynchos 30.60 2.00e-57 218.00
IUUC-Aca-004616 Anolis carolinensis 29.49 5.00e-62 233.00
IUUC-Aly-006145 Arabidopsis lyrata 40.30 7.00e-36 146.00
IUUC-Ath-006844 Arabidopsis thaliana 41.29 5.00e-38 153.00
IUUC-Ago-007750 Ashbya gossypii 32.29 1.00e-28 122.00
IUUC-Acl-008369 Aspergillus clavatus 28.23 2.00e-27 117.00
IUUC-Afl-008540 Aspergillus flavus 28.77 4.00e-27 117.00
IUUC-Afu-009089 Aspergillus fumigatus 26.40 4.00e-26 113.00
IUUC-Ani-009292 Aspergillus nidulans 28.72 7.00e-26 112.00
IUUC-Ang-009715 Aspergillus niger 25.00 3.00e-24 107.00
IUUC-Aor-009887 Aspergillus oryzae 28.77 3.00e-27 117.00
IUUC-Ate-010308 Aspergillus terreus 25.28 3.00e-15 77.40
IUUC-Ame-011345 Astyanax mexicanus 32.14 8.00e-68 252.00
IUUC-Bgr-012196 Blumeria graminis 29.05 2.00e-16 81.30
IUUC-Bta-012535 Bos taurus 32.24 8.00e-68 252.00
IUUC-Bci-013630 Botrytis cinerea 27.62 4.00e-28 120.00
IUUC-Bdi-014142 Brachypodium distachyon 40.67 1.00e-39 159.00
IUUC-Bol-015333 Brassica oleracea 42.29 3.00e-38 154.00
IUUC-Cel-018254 Caenorhabditis elegans 39.51 4.00e-38 153.00
IUUC-Cja-019469 Callithrix jacchus 32.90 9.00e-67 248.00
IUUC-Cfa-020640 Canis familiaris 32.55 2.00e-69 257.00
IUUC-Cpo-021322 Cavia porcellus 42.47 5.00e-62 233.00
IUUC-Cre-022677 Chlamydomonas reinhardtii 34.08 2.00e-25 110.00
IUUC-Csa-024234 Chlorocebus sabaeus 31.12 4.00e-64 239.00
IUUC-Cho-024709 Choloepus hoffmanni 42.47 2.00e-60 227.00
IUUC-Csv-026100 Ciona savignyi 36.33 3.00e-47 184.00
IUUC-Cgl-026482 Colletotrichum gloeosporioides 30.12 1.00e-09 58.90
IUUC-Cne-026789 Cryptococcus neoformans 28.20 1.00e-22 102.00
IUUC-Cme-027135 Cyanidioschyzon merolae 35.62 2.00e-09 58.90
IUUC-Dre-027405 Danio rerio 33.33 1.00e-60 228.00
IUUC-Dno-029874 Dasypus novemcinctus 27.56 2.00e-51 197.00
IUUC-Dor-030589 Dipodomys ordii 29.40 1.00e-64 241.00
IUUC-Dse-031427 Dothistroma septosporum 30.98 6.00e-35 142.00
IUUC-Ete-032459 Echinops telfairi 42.12 1.00e-61 231.00
IUUC-Eca-033218 Equus caballus 32.66 2.00e-66 248.00
IUUC-Eeu-035299 Erinaceus europaeus 29.04 4.00e-25 110.00
IUUC-Fca-036081 Felis catus 33.39 4.00e-67 249.00
IUUC-Fal-037561 Ficedula albicollis 29.47 6.00e-59 223.00
IUUC-Fox-037930 Fusarium oxysporum 28.14 3.00e-29 124.00
IUUC-Fso-038413 Fusarium solani 29.01 5.00e-28 120.00
IUUC-Gmo-039359 Gadus morhua 31.46 4.00e-65 243.00
IUUC-Ggr-039744 Gaeumannomyces graminis 25.00 3.00e-22 100.00
IUUC-Gga-041175 Gallus gallus 31.54 2.00e-61 231.00
IUUC-Gac-041943 Gasterosteus aculeatus 29.33 1.00e-62 235.00
IUUC-Gma-043888 Glycine max 42.36 6.00e-40 159.00
IUUC-Ggo-044912 Gorilla gorilla 31.80 4.00e-69 256.00
IUUC-Hsa-047016 Homo sapiens 31.49 4.00e-69 256.00
IUUC-Hvu-047059 Hordeum vulgare 41.15 1.00e-39 158.00
IUUC-Itr-048789 Ictidomys tridecemlineatus 42.81 5.00e-63 234.00
IUUC-Kpa-049133 Komagataella pastoris 29.80 4.00e-32 133.00
IUUC-Lch-049879 Latimeria chalumnae 26.87 3.00e-47 184.00
IUUC-Lpe-051455 Leersia perrieri 40.89 4.00e-39 157.00
IUUC-Loc-052799 Lepisosteus oculatus 32.79 7.00e-64 239.00
IUUC-Lma-052972 Leptosphaeria maculans 27.33 4.00e-28 120.00
IUUC-Laf-053479 Loxodonta africana 30.42 2.00e-70 261.00
IUUC-Mcc-055120 Macaca mulatta 29.69 5.00e-69 256.00
IUUC-Meu-055932 Macropus eugenii 36.26 1.00e-60 228.00
IUUC-Mor-057209 Magnaporthe oryzae 29.49 5.00e-28 120.00
IUUC-Mpo-057581 Magnaporthe poae 24.75 2.00e-18 88.60
IUUC-Mtr-058499 Medicago truncatula 42.86 3.00e-40 160.00
IUUC-Mla-059169 Melampsora laricipopulina 38.64 1.00e-22 97.80
IUUC-Mga-059800 Meleagris gallopavo 31.30 5.00e-61 229.00
IUUC-Mvi-060350 Microbotryum violaceum 36.11 1.00e-34 142.00
IUUC-Mmr-061548 Microcebus murinus 31.20 2.00e-69 257.00
IUUC-Mdo-062405 Monodelphis domestica 32.40 1.00e-65 245.00
IUUC-Mmu-064389 Mus musculus 32.65 3.00e-68 253.00
IUUC-Mac-064596 Musa acuminata 40.39 5.00e-38 153.00
IUUC-Mpu-065687 Mustela putorius furo 33.03 2.00e-69 257.00
IUUC-Mlu-067591 Myotis lucifugus 30.31 3.00e-63 237.00
IUUC-Nfi-068298 Neosartorya fischeri 27.64 4.00e-27 117.00
IUUC-Ncr-068876 Neurospora crassa 28.05 3.00e-29 124.00
IUUC-Nle-069799 Nomascus leucogenys 31.01 1.00e-65 244.00
IUUC-Opr-071155 Ochotona princeps 42.56 1.00e-62 234.00
IUUC-Ont-071290 Oreochromis niloticus 28.43 1.00e-64 242.00
IUUC-Ocu-074947 Oryctolagus cuniculus 31.43 8.00e-71 262.00
IUUC-Oba-075986 Oryza barthii 40.89 4.00e-39 157.00
IUUC-Obr-076304 Oryza brachyantha 41.38 3.00e-39 157.00
IUUC-Ogl-077600 Oryza glaberrima 40.89 4.00e-39 157.00
IUUC-Ogu-078079 Oryza glumaepatula 40.89 4.00e-39 157.00
IUUC-Oin-079935 Oryza indica 40.89 4.00e-39 156.00
IUUC-Olo-080897 Oryza longistaminata 40.89 4.00e-39 157.00
IUUC-Ome-081777 Oryza meridionalis 40.89 4.00e-39 157.00
IUUC-Oni-082298 Oryza nivara 40.89 4.00e-39 157.00
IUUC-Opu-083156 Oryza punctata 40.89 5.00e-39 156.00
IUUC-Oru-085243 Oryza rufipogon 40.89 3.00e-39 157.00
IUUC-Osa-086219 Oryza sativa 40.89 4.00e-39 157.00
IUUC-Ola-087202 Oryzias latipes 29.92 4.00e-59 223.00
IUUC-Olu-087800 Ostreococcus lucimarinus 30.83 1.00e-32 135.00
IUUC-Oga-088962 Otolemur garnettii 31.02 4.00e-70 259.00
IUUC-Oar-089858 Ovis aries 33.09 2.00e-67 251.00
IUUC-Ptr-090958 Pan troglodytes 31.80 5.00e-69 256.00
IUUC-Pan-092712 Papio anubis 29.84 3.00e-69 256.00
IUUC-Psi-093557 Pelodiscus sinensis 31.17 1.00e-67 251.00
IUUC-Pma-094131 Petromyzon marinus 33.86 5.00e-41 160.00
IUUC-Pno-094947 Phaeosphaeria nodorum 28.28 5.00e-28 119.00
IUUC-Ppa-095258 Physcomitrella patens 40.39 1.00e-38 155.00
IUUC-Pfo-097035 Poecilia formosa 31.62 3.00e-62 233.00
IUUC-Pab-097897 Pongo abelii 42.47 2.00e-62 234.00
IUUC-Pop-099487 Populus trichocarpa 43.35 2.00e-40 160.00
IUUC-Pca-100688 Procavia capensis 37.01 4.00e-50 193.00
IUUC-Ppe-101821 Prunus persica 42.50 5.00e-40 159.00
IUUC-Pva-102632 Pteropus vampyrus 42.37 6.00e-62 232.00
IUUC-Pgr-103311 Puccinia graminis 29.29 2.00e-30 128.00
IUUC-Ptt-103825 Puccinia triticina 27.14 6.00e-21 96.30
IUUC-Pte-104036 Pyrenophora teres 27.00 3.00e-24 107.00
IUUC-Pyt-104460 Pyrenophora triticirepentis 27.00 4.00e-24 107.00
IUUC-Rno-104852 Rattus norvegicus 32.36 8.00e-71 262.00
IUUC-Sce-106305 Saccharomyces cerevisiae 30.69 1.00e-26 115.00
IUUC-Sja-107896 Schizosaccharomyces japonicus 33.61 3.00e-30 127.00
IUUC-Spo-108267 Schizosaccharomyces pombe 25.51 1.00e-32 135.00
IUUC-Smo-109180 Selaginella moellendorffii 32.57 4.00e-34 140.00
IUUC-Sit-110615 Setaria italica 39.53 4.00e-38 154.00
IUUC-Sly-111861 Solanum lycopersicum 44.33 2.00e-39 157.00
IUUC-Stu-112373 Solanum tuberosum 44.33 1.00e-39 158.00
IUUC-Sar-113666 Sorex araneus 31.54 2.00e-67 251.00
IUUC-Sbi-114597 Sorghum bicolor 40.67 1.00e-39 158.00
IUUC-Sre-114965 Sporisorium reilianum 36.02 1.00e-33 138.00
IUUC-Ssc-115866 Sus scrofa 32.67 2.00e-70 261.00
IUUC-Tgu-117521 Taeniopygia guttata 31.66 4.00e-64 240.00
IUUC-Tru-117803 Takifugu rubripes 30.02 4.00e-60 226.00
IUUC-Tsy-119135 Tarsius syrichta 29.90 7.00e-62 232.00
IUUC-Tni-119807 Tetraodon nigroviridis 28.99 8.00e-61 229.00
IUUC-Tca-121036 Theobroma cacao 42.86 2.00e-40 161.00
IUUC-Tre-121942 Trichoderma reesei 32.67 1.00e-35 145.00
IUUC-Tvi-122453 Trichoderma virens 29.49 4.00e-33 136.00
IUUC-Tae-123061 Triticum aestivum 40.67 1.00e-38 155.00
IUUC-Tur-126021 Triticum urartu 40.67 1.00e-38 155.00
IUUC-Tme-126889 Tuber melanosporum 30.20 2.00e-31 131.00
IUUC-Tbe-127297 Tupaia belangeri 42.11 2.00e-38 154.00
IUUC-Ttr-128745 Tursiops truncatus 32.72 6.00e-70 259.00
IUUC-Uma-129552 Ustilago maydis 36.97 2.00e-34 141.00
IUUC-Vda-129838 Verticillium dahliae 30.33 3.00e-28 120.00
IUUC-Vpa-130567 Vicugna pacos 31.06 2.00e-69 257.00
IUUC-Vvi-131418 Vitis vinifera 45.32 2.00e-43 171.00
IUUC-Xtr-132926 Xenopus tropicalis 33.33 1.00e-70 261.00
IUUC-Xma-134278 Xiphophorus maculatus 33.51 1.00e-65 245.00
IUUC-Yli-134476 Yarrowia lipolytica 31.71 1.00e-33 138.00
IUUC-Zma-135611 Zea mays 41.15 1.00e-39 158.00
Created Date 25-Jun-2017

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