iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFAC
Protein-protein Interaction
iRefIndex	PINA	HINT	Mentha
Protein 3D Structure
PDB	MMDB
Post-translational Modifications (PTMs)
dbPPT	dbPTM
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/ZnF/Other	27.74	2.00e-05	45.10	IUUC-Sce-106145

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Arabidopsis thaliana

Functional Description
(View)

May be part of a complex that binds ubiquitinated proteins and that is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome.

Protein Sequence
(Fasta)

MTMLRVRSRD GLERVSVDGP HITVSQLKTL IQDQLQIPIH NQTLSTNRNL LLAKSPSDFL 60
AFTDMADPNL RISSLNLAHG SMVYLAYEGE RTIRGGPAVT PAGSFGRKMT VEDLIARQMR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTGTCTTCT GGGGCTTATC GATTCTTCCT TAAACTGGGA AACTACTTTG TTCGAATCTC 60
AGAGCTTTTT CGTTTCCCAT CGGAAGAAGA AACTCATATA TACCTTCCAA AAAATCCATA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR007717--NPL4_C
IPR024682--Npl4_Ub-like_dom
IPR029071--Ubiquitin-rel_dom

Pfam

PF05021--NPL4
PF11543--UN_NPL4

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0043130--F:ubiquitin binding
GO:0031625--F:ubiquitin protein ligase binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ath:AT3G63000

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002939	Amborella trichopoda	72.44	1.00e-175	608.00
IUUC-Aly-005413	Arabidopsis lyrata	96.60	0.00e+00	784.00
IUUC-Ame-011438	Astyanax mexicanus	31.91	4.00e-09	53.10
IUUC-Bgr-012124	Blumeria graminis	21.56	1.00e-06	47.80
IUUC-Bol-016294	Brassica oleracea	90.05	0.00e+00	781.00
IUUC-Bra-017023	Brassica rapa	90.78	0.00e+00	754.00
IUUC-Cel-018713	Caenorhabditis elegans	25.67	3.00e-08	52.80
IUUC-Cgl-026685	Colletotrichum gloeosporioides	23.12	3.00e-06	46.60
IUUC-Cne-026794	Cryptococcus neoformans	25.61	1.00e-04	41.20
IUUC-Dse-031202	Dothistroma septosporum	28.57	6.00e-09	55.10
IUUC-Eeu-034485	Erinaceus europaeus	24.22	1.00e-13	70.90
IUUC-Fso-038152	Fusarium solani	25.55	4.00e-11	62.80
IUUC-Gma-044178	Glycine max	74.09	8.00e-160	555.00
IUUC-Hvu-047323	Hordeum vulgare	62.56	7.00e-71	259.00
IUUC-Lma-053092	Leptosphaeria maculans	26.30	2.00e-12	67.00
IUUC-Meu-056460	Macropus eugenii	36.51	1.00e-03	37.70
IUUC-Mor-057189	Magnaporthe oryzae	25.08	1.00e-09	57.80
IUUC-Mpo-057366	Magnaporthe poae	24.61	5.00e-09	55.50
IUUC-Mtr-057834	Medicago truncatula	72.88	5.00e-165	573.00
IUUC-Mla-059190	Melampsora laricipopulina	24.42	3.00e-05	43.50
IUUC-Mvi-060275	Microbotryum violaceum	24.40	1.00e-06	47.80
IUUC-Ncr-068936	Neurospora crassa	25.24	9.00e-08	51.20
IUUC-Olu-087601	Ostreococcus lucimarinus	42.18	3.00e-77	281.00
IUUC-Pgr-103626	Puccinia graminis	25.91	1.00e-06	47.80
IUUC-Sce-106145	Saccharomyces cerevisiae	27.74	6.00e-06	45.40
IUUC-Smo-108933	Selaginella moellendorffii	58.01	9.00e-134	469.00
IUUC-Sbi-113987	Sorghum bicolor	57.55	3.00e-122	431.00
IUUC-Sre-115095	Sporisorium reilianum	26.56	7.00e-07	48.90
IUUC-Tsy-118993	Tarsius syrichta	24.55	4.00e-14	72.40
IUUC-Tca-121169	Theobroma cacao	75.67	2.00e-180	624.00
IUUC-Tre-122046	Trichoderma reesei	24.76	6.00e-11	62.00
IUUC-Tme-127123	Tuber melanosporum	26.92	4.00e-13	69.30
IUUC-Uma-129492	Ustilago maydis	26.56	7.00e-07	48.90

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence