iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118644

UUCD1 version

UUC-TaR-00910

Ensembl Protein ID

ENSTRUP00000042121.1

UniProt Accession

H2UYU2; H2UYU2_TAKRU

Protein Name

Uncharacterized protein

Gene Name

klhl22

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000016481.1	ENSTRUT00000042263.1	ENSTRUP00000042119.1
ENSTRUG00000016481.1	ENSTRUT00000042264.1	ENSTRUP00000042120.1
ENSTRUG00000016481.1	ENSTRUT00000042265.1	ENSTRUP00000042121.1
ENSTRUG00000016481.1	ENSTRUT00000042266.1	ENSTRUP00000042122.1
ENSTRUG00000016481.1	ENSTRUT00000042267.1	ENSTRUP00000042123.1
ENSTRUG00000016481.1	ENSTRUT00000042268.1	ENSTRUP00000042124.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	6.80e-19	69.2	49	113
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	9.10e-06	25.0	148	177

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           Dv+l v+g+ ++ah+i Laas+++F+ +f ++l+es+ ++++ i++v+ ++++ ll+++Yt+++++
   Q: 49   DVVLLVEGRPIQAHRILLAASCHYFRGMFAGGLRESE-QKEISIHGVSFTAMKKLLDYIYTSEIEL 113
           9***********************************8.************************9875 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhF 31
           +N++++ r+Ad y++ +L+ ++++++l++ 
   Q: 148  SNVVEVHRLADVYGLQQLNAKVHSYLLRNI 177
           8**************************996 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

TADDAEASQG GGETSSSGRQ GRRTFRCSGH FRSLLDGVLT LRQSGVLYDV VLLVEGRPIQ 60
AHRILLAASC HYFRGMFAGG LRESEQKEIS IHGVSFTAMK KLLDYIYTSE IELDLECVQE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACAGCAG ATAAAATCGC TGCTGATTAT CTGCTGCAGA AACTCCCAAT CAGCCAATCA 60
ATCAATCACC TGACTGATTA CAGCCGGTGT GTCTGTCAGG AAATGAATGA CGTGTGTGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030575--KLHL22
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0005813--C:centrosome
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0072686--C:mitotic spindle
GO:0005827--C:polar microtubule
GO:0051301--P:cell division
GO:0007094--P:mitotic spindle assembly checkpoint
GO:0006513--P:protein monoubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002097	Ailuropoda melanoleuca	58.13	0.00e+00	701.00
IUUC-Apl-004081	Anas platyrhynchos	57.28	0.00e+00	735.00
IUUC-Aca-005015	Anolis carolinensis	55.03	0.00e+00	677.00
IUUC-Ang-009879	Aspergillus niger	29.38	2.00e-07	49.70
IUUC-Ame-011712	Astyanax mexicanus	66.61	0.00e+00	882.00
IUUC-Bta-012594	Bos taurus	57.49	0.00e+00	704.00
IUUC-Cja-019752	Callithrix jacchus	56.60	1.00e-164	572.00
IUUC-Cfa-020884	Canis familiaris	57.67	0.00e+00	704.00
IUUC-Cpo-021711	Cavia porcellus	58.36	0.00e+00	716.00
IUUC-Cre-022656	Chlamydomonas reinhardtii	33.09	5.00e-11	62.40
IUUC-Csa-023211	Chlorocebus sabaeus	58.01	0.00e+00	706.00
IUUC-Dre-028395	Danio rerio	66.13	0.00e+00	904.00
IUUC-Dno-030096	Dasypus novemcinctus	56.62	0.00e+00	694.00
IUUC-Dor-030709	Dipodomys ordii	55.49	2.00e-113	402.00
IUUC-Eca-033388	Equus caballus	57.49	0.00e+00	704.00
IUUC-Eeu-034616	Erinaceus europaeus	51.28	1.00e-179	622.00
IUUC-Fca-035815	Felis catus	57.84	0.00e+00	706.00
IUUC-Fal-037311	Ficedula albicollis	59.01	0.00e+00	714.00
IUUC-Gmo-039571	Gadus morhua	63.08	0.00e+00	706.00
IUUC-Gga-040992	Gallus gallus	57.12	0.00e+00	735.00
IUUC-Gac-042041	Gasterosteus aculeatus	71.31	0.00e+00	931.00
IUUC-Ggo-045141	Gorilla gorilla	54.59	0.00e+00	657.00
IUUC-Hsa-045984	Homo sapiens	58.01	0.00e+00	707.00
IUUC-Itr-048890	Ictidomys tridecemlineatus	57.84	0.00e+00	708.00
IUUC-Lch-049700	Latimeria chalumnae	51.07	1.00e-175	609.00
IUUC-Loc-052141	Lepisosteus oculatus	61.90	0.00e+00	825.00
IUUC-Laf-053487	Loxodonta africana	57.49	0.00e+00	702.00
IUUC-Mcc-054682	Macaca mulatta	58.73	2.00e-175	608.00
IUUC-Meu-055937	Macropus eugenii	51.07	0.00e+00	636.00
IUUC-Mga-059953	Meleagris gallopavo	57.12	0.00e+00	735.00
IUUC-Mmr-061743	Microcebus murinus	58.01	0.00e+00	709.00
IUUC-Mdo-062328	Monodelphis domestica	56.93	0.00e+00	709.00
IUUC-Mmu-063979	Mus musculus	57.67	0.00e+00	706.00
IUUC-Mpu-066750	Mustela putorius furo	58.01	0.00e+00	707.00
IUUC-Mlu-066960	Myotis lucifugus	58.19	0.00e+00	711.00
IUUC-Nle-069690	Nomascus leucogenys	57.09	0.00e+00	637.00
IUUC-Opr-071059	Ochotona princeps	54.07	0.00e+00	645.00
IUUC-Ont-072004	Oreochromis niloticus	73.68	0.00e+00	900.00
IUUC-Oan-073172	Ornithorhynchus anatinus	51.81	2.00e-164	572.00
IUUC-Ola-086599	Oryzias latipes	73.35	0.00e+00	970.00
IUUC-Oga-087980	Otolemur garnettii	57.84	0.00e+00	709.00
IUUC-Oar-089956	Ovis aries	48.78	3.00e-150	525.00
IUUC-Ptr-090598	Pan troglodytes	57.25	0.00e+00	641.00
IUUC-Pan-092387	Papio anubis	58.93	4.00e-176	611.00
IUUC-Psi-093484	Pelodiscus sinensis	56.13	0.00e+00	724.00
IUUC-Pma-094224	Petromyzon marinus	47.59	3.00e-164	572.00
IUUC-Pfo-096149	Poecilia formosa	70.85	0.00e+00	952.00
IUUC-Pab-098097	Pongo abelii	58.19	0.00e+00	709.00
IUUC-Pca-100118	Procavia capensis	56.07	7.00e-115	407.00
IUUC-Rno-105350	Rattus norvegicus	57.84	0.00e+00	708.00
IUUC-Sar-113490	Sorex araneus	56.10	1.00e-111	397.00
IUUC-Ssc-115827	Sus scrofa	57.32	0.00e+00	696.00
IUUC-Tgu-116748	Taeniopygia guttata	60.34	0.00e+00	682.00
IUUC-Tsy-118888	Tarsius syrichta	52.39	4.00e-163	568.00
IUUC-Tni-120060	Tetraodon nigroviridis	78.16	0.00e+00	907.00
IUUC-Tme-127039	Tuber melanosporum	39.74	3.00e-11	64.30
IUUC-Ttr-129183	Tursiops truncatus	56.60	0.00e+00	634.00
IUUC-Xtr-132780	Xenopus tropicalis	55.28	0.00e+00	719.00
IUUC-Xma-133062	Xiphophorus maculatus	71.45	0.00e+00	948.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence