iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Rno-105131

UUCD1 version

UUC-RaN-00948

Ensembl Protein ID

ENSRNOP00000009295.5

UniProt Accession

A0A0G2QC41; A0A0G2QC41_RAT

Genbank Protein ID

ENSRNOP00000009295

Protein Name

Histone deacetylase 6

Genbank Nucleotide ID

AABR07037193

Gene Name

LOC103689963; Hdac6; LOC108348065

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000048738.2	ENSRNOT00000009295.6	ENSRNOP00000009295.5

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFAC	RAID2
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/ZnF/ZnF_UBP	71.89	0.00e+00	1644.00	IUUC-Hsa-046904

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MTSTGQDSST RQRKSRHNPQ SPLQDSSATL KRGGKKGAVP HSSPNLAEVK KKGKMKKLSQ 60
PAEEDLIVGL QGLDLNSETR VPVGTGLVFD EQLNDFHCLW DDSFPENPER LHAIKEQLIL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGAAGGATTC TGCTCGAAAG GGGCAGTCCT CTGAGCAGCG GGGCAAAGGG GAAAGCTGGG 60
GGCGAGATCT GTGAGAGAGG AAGGTGCGGG CTCGGCCCTA CAGGAGGTGG AGTTGAGTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR000286--His_deacetylse
IPR023801--His_deacetylse_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50271--ZF_UBP

Pfam

PF00850--Hist_deacetyl
PF02148--zf-UBP

PRINTS

PR01270--HDASUPER

SMART

SM00290--ZnF_UBP

Gene Ontology

GO:0030424--C:axon
GO:1904115--C:axon cytoplasm
GO:0005813--C:centrosome
GO:0016787--F:hydrolase activity
GO:0008270--F:zinc ion binding
GO:0019896--P:axonal transport of mitochondrion
GO:0034599--P:cellular response to oxidative stress
GO:0071374--P:cellular response to parathyroid hormone stimulus
GO:0048843--P:negative regulation of axon extension involved in axon guidance
GO:0010977--P:negative regulation of neuron projection development
GO:1901984--P:negative regulation of protein acetylation
GO:0030182--P:neuron differentiation
GO:1904056--P:positive regulation of cholangiocyte proliferation
GO:0050775--P:positive regulation of dendrite morphogenesis
GO:1903223--P:positive regulation of oxidative stress-induced neuron death
GO:0051968--P:positive regulation of synaptic transmission, glutamatergic
GO:0090044--P:positive regulation of tubulin deacetylation
GO:0070507--P:regulation of microtubule cytoskeleton organization
GO:0010821--P:regulation of mitochondrion organization
GO:0001932--P:regulation of protein phosphorylation
GO:0001975--P:response to amphetamine
GO:0051412--P:response to corticosterone
GO:0071548--P:response to dexamethasone
GO:0035902--P:response to immobilization stress

KEGG

rno:108348065; rno:84581

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000749	Aegilops tauschii	42.02	6.00e-71	261.00
IUUC-Aml-002087	Ailuropoda melanoleuca	75.74	0.00e+00	1694.00
IUUC-Atr-002745	Amborella trichopoda	46.02	2.00e-89	323.00
IUUC-Aca-004303	Anolis carolinensis	58.97	0.00e+00	1007.00
IUUC-Aly-006432	Arabidopsis lyrata	46.43	3.00e-84	306.00
IUUC-Ath-007355	Arabidopsis thaliana	46.45	4.00e-89	322.00
IUUC-Ago-007972	Ashbya gossypii	42.29	2.00e-85	310.00
IUUC-Afl-008399	Aspergillus flavus	49.46	4.00e-50	192.00
IUUC-Afu-008954	Aspergillus fumigatus	41.29	5.00e-76	278.00
IUUC-Ani-009142	Aspergillus nidulans	44.23	2.00e-80	293.00
IUUC-Ang-009522	Aspergillus niger	34.03	2.00e-45	177.00
IUUC-Aor-010069	Aspergillus oryzae	44.54	3.00e-78	286.00
IUUC-Ate-010291	Aspergillus terreus	44.85	2.00e-88	320.00
IUUC-Ame-010780	Astyanax mexicanus	52.18	0.00e+00	781.00
IUUC-Bta-013052	Bos taurus	73.01	0.00e+00	1595.00
IUUC-Bdi-014007	Brachypodium distachyon	44.51	2.00e-87	317.00
IUUC-Bol-015468	Brassica oleracea	46.11	3.00e-88	319.00
IUUC-Bra-016680	Brassica rapa	46.37	2.00e-88	320.00
IUUC-Cel-018220	Caenorhabditis elegans	39.97	2.00e-153	536.00
IUUC-Cja-019473	Callithrix jacchus	71.65	0.00e+00	1612.00
IUUC-Cfa-020263	Canis familiaris	75.22	0.00e+00	1650.00
IUUC-Cpo-021691	Cavia porcellus	76.96	0.00e+00	1746.00
IUUC-Cre-022561	Chlamydomonas reinhardtii	53.51	4.00e-57	214.00
IUUC-Csa-024223	Chlorocebus sabaeus	74.92	0.00e+00	1708.00
IUUC-Cgl-026709	Colletotrichum gloeosporioides	38.46	5.00e-77	282.00
IUUC-Cne-026978	Cryptococcus neoformans	44.95	1.00e-93	337.00
IUUC-Dre-028820	Danio rerio	57.66	0.00e+00	929.00
IUUC-Dno-029160	Dasypus novemcinctus	67.61	0.00e+00	1462.00
IUUC-Dor-030859	Dipodomys ordii	71.87	0.00e+00	1661.00
IUUC-Dse-031186	Dothistroma septosporum	40.41	2.00e-79	290.00
IUUC-Dme-031963	Drosophila melanogaster	45.42	0.00e+00	699.00
IUUC-Ete-032279	Echinops telfairi	62.56	1.00e-148	520.00
IUUC-Eca-033842	Equus caballus	75.19	0.00e+00	1716.00
IUUC-Eeu-034487	Erinaceus europaeus	75.26	3.00e-149	523.00
IUUC-Fca-036430	Felis catus	76.09	0.00e+00	1667.00
IUUC-Fox-038067	Fusarium oxysporum	42.64	4.00e-80	292.00
IUUC-Fso-038263	Fusarium solani	40.35	3.00e-81	296.00
IUUC-Ggr-040062	Gaeumannomyces graminis	43.99	4.00e-74	272.00
IUUC-Ggo-045022	Gorilla gorilla	74.75	0.00e+00	1704.00
IUUC-Hsa-046904	Homo sapiens	74.75	0.00e+00	1702.00
IUUC-Itr-048484	Ictidomys tridecemlineatus	79.47	0.00e+00	1801.00
IUUC-Lch-050330	Latimeria chalumnae	46.07	0.00e+00	935.00
IUUC-Lpe-051214	Leersia perrieri	42.33	3.00e-88	319.00
IUUC-Lma-053263	Leptosphaeria maculans	45.72	1.00e-90	328.00
IUUC-Laf-053386	Loxodonta africana	72.84	0.00e+00	1611.00
IUUC-Mcc-055530	Macaca mulatta	75.00	0.00e+00	1709.00
IUUC-Meu-056442	Macropus eugenii	68.21	0.00e+00	979.00
IUUC-Mor-057095	Magnaporthe oryzae	39.60	1.00e-83	304.00
IUUC-Mpo-057389	Magnaporthe poae	43.40	2.00e-73	270.00
IUUC-Mtr-058463	Medicago truncatula	45.68	2.00e-90	326.00
IUUC-Mla-059143	Melampsora laricipopulina	42.13	2.00e-85	309.00
IUUC-Mmr-060637	Microcebus murinus	74.63	0.00e+00	1717.00
IUUC-Mdo-062198	Monodelphis domestica	68.14	0.00e+00	1085.00
IUUC-Mmu-063346	Mus musculus	92.17	0.00e+00	2076.00
IUUC-Mac-064630	Musa acuminata	44.54	4.00e-86	312.00
IUUC-Mpu-065884	Mustela putorius furo	74.96	0.00e+00	1703.00
IUUC-Mlu-068117	Myotis lucifugus	73.22	0.00e+00	1606.00
IUUC-Nfi-068404	Neosartorya fischeri	44.65	2.00e-87	317.00
IUUC-Ncr-068672	Neurospora crassa	39.21	1.00e-78	288.00
IUUC-Nle-069868	Nomascus leucogenys	88.48	0.00e+00	714.00
IUUC-Opr-071074	Ochotona princeps	62.48	0.00e+00	968.00
IUUC-Ont-072246	Oreochromis niloticus	51.77	0.00e+00	791.00
IUUC-Ocu-074627	Oryctolagus cuniculus	76.01	0.00e+00	1752.00
IUUC-Oba-075489	Oryza barthii	46.95	7.00e-86	311.00
IUUC-Obr-076150	Oryza brachyantha	47.09	2.00e-86	313.00
IUUC-Ogl-077437	Oryza glaberrima	44.41	4.00e-86	312.00
IUUC-Oin-079210	Oryza indica	44.69	8.00e-87	315.00
IUUC-Olo-080971	Oryza longistaminata	47.52	4.00e-74	272.00
IUUC-Opu-083471	Oryza punctata	46.18	4.00e-86	312.00
IUUC-Oru-084755	Oryza rufipogon	44.60	7.00e-87	315.00
IUUC-Oga-089155	Otolemur garnettii	73.05	0.00e+00	1671.00
IUUC-Oar-089620	Ovis aries	73.01	0.00e+00	1590.00
IUUC-Ptr-090812	Pan troglodytes	85.71	0.00e+00	1222.00
IUUC-Pan-092340	Papio anubis	74.92	0.00e+00	1701.00
IUUC-Pma-094386	Petromyzon marinus	53.18	0.00e+00	823.00
IUUC-Pno-095131	Phaeosphaeria nodorum	47.18	2.00e-78	286.00
IUUC-Ppa-095550	Physcomitrella patens	48.06	3.00e-88	319.00
IUUC-Pfo-096110	Poecilia formosa	49.03	0.00e+00	880.00
IUUC-Pab-098422	Pongo abelii	73.74	0.00e+00	1664.00
IUUC-Pop-099174	Populus trichocarpa	43.68	8.00e-83	301.00
IUUC-Pca-100833	Procavia capensis	69.94	0.00e+00	1466.00
IUUC-Pva-102410	Pteropus vampyrus	69.86	0.00e+00	1507.00
IUUC-Ptt-103841	Puccinia triticina	39.27	8.00e-84	305.00
IUUC-Pte-104383	Pyrenophora teres	44.39	4.00e-87	316.00
IUUC-Pyt-104427	Pyrenophora triticirepentis	44.92	1.00e-87	317.00
IUUC-Sce-106274	Saccharomyces cerevisiae	41.49	2.00e-81	296.00
IUUC-Sha-106661	Sarcophilus harrisii	55.49	0.00e+00	817.00
IUUC-Sja-107915	Schizosaccharomyces japonicus	43.09	1.00e-91	330.00
IUUC-Spo-108300	Schizosaccharomyces pombe	46.99	5.00e-94	338.00
IUUC-Smo-109615	Selaginella moellendorffii	46.68	7.00e-92	331.00
IUUC-Sit-110160	Setaria italica	44.48	3.00e-82	300.00
IUUC-Sly-111164	Solanum lycopersicum	41.00	7.00e-86	311.00
IUUC-Stu-112685	Solanum tuberosum	43.05	1.00e-74	274.00
IUUC-Sar-113692	Sorex araneus	65.39	0.00e+00	746.00
IUUC-Sbi-114301	Sorghum bicolor	44.38	2.00e-81	297.00
IUUC-Sre-115013	Sporisorium reilianum	44.13	1.00e-84	308.00
IUUC-Ssc-115724	Sus scrofa	73.60	0.00e+00	1543.00
IUUC-Tgu-116605	Taeniopygia guttata	48.50	0.00e+00	698.00
IUUC-Tru-117614	Takifugu rubripes	48.25	0.00e+00	978.00
IUUC-Tni-119809	Tetraodon nigroviridis	55.51	0.00e+00	791.00
IUUC-Tca-121312	Theobroma cacao	45.18	2.00e-87	317.00
IUUC-Tre-121930	Trichoderma reesei	40.45	6.00e-83	301.00
IUUC-Tvi-122373	Trichoderma virens	40.94	4.00e-83	302.00
IUUC-Tae-123064	Triticum aestivum	41.87	2.00e-78	286.00
IUUC-Tbe-127675	Tupaia belangeri	83.44	5.00e-72	266.00
IUUC-Ttr-128411	Tursiops truncatus	73.44	0.00e+00	1643.00
IUUC-Uma-129408	Ustilago maydis	47.44	3.00e-78	286.00
IUUC-Vda-129994	Verticillium dahliae	39.36	8.00e-76	278.00
IUUC-Vpa-130525	Vicugna pacos	73.40	3.00e-54	207.00
IUUC-Vvi-131038	Vitis vinifera	44.01	8.00e-89	321.00
IUUC-Xtr-132618	Xenopus tropicalis	51.48	0.00e+00	1092.00
IUUC-Yli-134680	Yarrowia lipolytica	40.60	1.00e-88	320.00
IUUC-Zma-135110	Zea mays	44.19	1.00e-82	300.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence