iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Csa-023145

Ensembl Protein ID

ENSCSAP00000003963.1

UniProt Accession

A0A0D9R5S4; A0A0D9R5S4_CHLSB

Genbank Protein ID

ENSCSAP00000003963

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

AQIB01148383

Gene Name

USP22

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAG00000007698.1	ENSCSAT00000005748.1	ENSCSAP00000003963.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.30e-93	311.8	177	520

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           Gl NlgNtC+mN+++Q+L+++p lr+++l+ ++++++ +   +p+ +l++++ +lf+e+++++++   p +ll+ +++ a+++ gyeqq
   Q: 177  GLINLGNTCFMNCIVQALTHTPLLRDFFLS-DRHRCEMQ---SPSSCLVCEMSSLFQEFYSGHRSPHIPYKLLHLVWTHARHLAGYEQQ 261
           9*****************************.99999875...78********************************************* PP
   S: 91   DaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgk 179
           Da+Efl   ld l++++k                  ++ ++ +++++ +++i+++F g l+s+++c+ c+ vs++ +pf+d+sl++pg+
   Q: 262  DAHEFLIAALDVLHRHCKG----------------DDNGKKANNPNHCNCIIDQIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGS 334
           *****************22................22335677899999**************************************** PP
   S: 180  eetkke....................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrek 248
           ++   +                    +l+dcL+ ft++e+l ++ k++c+ c+++qe++k+l++kklP v ++hLkRf  +++ k r+k
   Q: 335  STPFWPlspgsegnvvngeshvsgttTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKKLPIVACFHLKRF--EHSAKLRRK 421
           *877779***********************************************************************..5666899** PP
   S: 249  inkkvefpleLdlspfcts............peekqkekkkYeLiavvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevlee 325
           i+++v+fpleLd++pf++s            p+++ ++++kY+L+avv+H+G+l+sGHY+++++++k++W+++dD  +t+ + ++vl  
   Q: 422  ITTYVSFPLELDMTPFMASskesrmngqyqqPTDSLNNDNKYSLFAVVNHQGTLESGHYTSFIRQHKDQWFKCDDAIITKASIKDVLD- 509
           *******************5555555555554445555**************************************************. PP
   S: 326  tgstaYvlfYkrr 338
             s++Y+lfY+++
   Q: 510  --SEGYLLFYHKQ 520
           ..********985 PP

Organism

Chlorocebus sabaeus

Protein Sequence
(Fasta)

MVSRPEPEGE AMDAELAVAP PGCSHLGSFK VDNWKQNLRA IYQCFVWSGT AEARKRKAKS 60
CICHVCGVHL NRLHSCLYCV FFGCFTKKHI HEHAKSKRHN LAIDLMYGGI YCFLCQDYIY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAACCGGGAG AGCGCAGCGC GGGCGGCCAG CAGCAGCCGC AGCTCGGGGG CGGTGCCTGC 60
CCCGCAGCCT CCCCTCCGCG ATCGCGCAGA CCCATCTTTG TCTGGCCTCC GCGCTTTGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH
PF02148--zf-UBP

Gene Ontology

GO:0000124--C:SAGA complex
GO:0010485--F:H4 histone acetyltransferase activity
GO:0030374--F:ligand-dependent nuclear receptor transcription coactivator activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0016578--P:histone deubiquitination
GO:0016574--P:histone ubiquitination
GO:0045931--P:positive regulation of mitotic cell cycle
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000393	Aegilops tauschii	37.85	2.00e-65	243.00
IUUC-Aml-001343	Ailuropoda melanoleuca	96.57	0.00e+00	1069.00
IUUC-Atr-002653	Amborella trichopoda	37.43	3.00e-100	359.00
IUUC-Apl-003433	Anas platyrhynchos	93.39	0.00e+00	953.00
IUUC-Aca-005347	Anolis carolinensis	88.89	0.00e+00	1006.00
IUUC-Aly-006565	Arabidopsis lyrata	34.91	3.00e-72	265.00
IUUC-Ath-007536	Arabidopsis thaliana	34.89	2.00e-72	266.00
IUUC-Ago-007811	Ashbya gossypii	30.40	2.00e-53	202.00
IUUC-Acl-008124	Aspergillus clavatus	30.41	2.00e-59	223.00
IUUC-Afl-008464	Aspergillus flavus	33.01	6.00e-55	207.00
IUUC-Afu-008912	Aspergillus fumigatus	31.63	4.00e-57	215.00
IUUC-Ani-009168	Aspergillus nidulans	32.56	2.00e-58	219.00
IUUC-Aor-010035	Aspergillus oryzae	35.21	1.00e-38	152.00
IUUC-Ate-010382	Aspergillus terreus	31.81	9.00e-53	200.00
IUUC-Ame-011253	Astyanax mexicanus	85.99	0.00e+00	839.00
IUUC-Bgr-012150	Blumeria graminis	32.24	1.00e-48	187.00
IUUC-Bta-013303	Bos taurus	97.47	0.00e+00	1061.00
IUUC-Bci-013604	Botrytis cinerea	33.19	2.00e-57	216.00
IUUC-Bdi-014171	Brachypodium distachyon	35.68	5.00e-77	281.00
IUUC-Bol-016509	Brassica oleracea	34.92	2.00e-73	270.00
IUUC-Cja-019283	Callithrix jacchus	99.53	0.00e+00	890.00
IUUC-Cfa-021239	Canis familiaris	98.09	0.00e+00	976.00
IUUC-Cpo-022354	Cavia porcellus	97.90	0.00e+00	1083.00
IUUC-Cho-024938	Choloepus hoffmanni	97.41	8.00e-67	247.00
IUUC-Cin-025109	Ciona intestinalis	57.82	2.00e-122	431.00
IUUC-Csv-026214	Ciona savignyi	55.85	5.00e-174	603.00
IUUC-Cgl-026457	Colletotrichum gloeosporioides	32.53	8.00e-56	211.00
IUUC-Cne-027085	Cryptococcus neoformans	32.76	2.00e-63	236.00
IUUC-Dre-027433	Danio rerio	93.80	0.00e+00	928.00
IUUC-Dno-030095	Dasypus novemcinctus	97.44	0.00e+00	971.00
IUUC-Dor-030481	Dipodomys ordii	98.27	7.00e-102	363.00
IUUC-Dse-031415	Dothistroma septosporum	30.74	6.00e-61	228.00
IUUC-Dme-032074	Drosophila melanogaster	51.23	1.00e-138	486.00
IUUC-Ete-033175	Echinops telfairi	79.13	0.00e+00	738.00
IUUC-Eca-033736	Equus caballus	97.87	0.00e+00	969.00
IUUC-Eeu-034814	Erinaceus europaeus	93.91	4.00e-133	468.00
IUUC-Fca-035861	Felis catus	98.51	0.00e+00	976.00
IUUC-Fal-037645	Ficedula albicollis	93.49	0.00e+00	939.00
IUUC-Fox-038046	Fusarium oxysporum	32.81	9.00e-57	214.00
IUUC-Fso-038321	Fusarium solani	33.86	1.00e-56	214.00
IUUC-Gmo-038474	Gadus morhua	94.26	2.00e-171	595.00
IUUC-Ggr-040044	Gaeumannomyces graminis	32.60	4.00e-57	215.00
IUUC-Gga-040624	Gallus gallus	92.00	0.00e+00	1018.00
IUUC-Gac-042197	Gasterosteus aculeatus	86.10	0.00e+00	928.00
IUUC-Gma-042897	Glycine max	33.16	5.00e-85	308.00
IUUC-Ggo-044409	Gorilla gorilla	99.43	0.00e+00	1101.00
IUUC-Hsa-046521	Homo sapiens	99.62	0.00e+00	1103.00
IUUC-Hvu-047739	Hordeum vulgare	38.95	3.00e-70	258.00
IUUC-Itr-048375	Ictidomys tridecemlineatus	98.44	0.00e+00	1069.00
IUUC-Kpa-049135	Komagataella pastoris	35.84	5.00e-69	255.00
IUUC-Lch-050537	Latimeria chalumnae	93.90	0.00e+00	1023.00
IUUC-Lpe-050969	Leersia perrieri	38.37	5.00e-73	268.00
IUUC-Loc-052765	Lepisosteus oculatus	83.65	0.00e+00	909.00
IUUC-Lma-053105	Leptosphaeria maculans	33.47	3.00e-68	252.00
IUUC-Laf-053571	Loxodonta africana	98.08	0.00e+00	972.00
IUUC-Mcc-055166	Macaca mulatta	100.00	0.00e+00	1106.00
IUUC-Mor-057103	Magnaporthe oryzae	31.92	3.00e-57	216.00
IUUC-Mpo-057621	Magnaporthe poae	32.82	2.00e-56	213.00
IUUC-Mtr-057894	Medicago truncatula	37.24	2.00e-85	310.00
IUUC-Mla-059185	Melampsora laricipopulina	30.41	1.00e-43	171.00
IUUC-Mga-059709	Meleagris gallopavo	93.39	0.00e+00	953.00
IUUC-Mvi-060530	Microbotryum violaceum	34.25	9.00e-59	221.00
IUUC-Mmr-060988	Microcebus murinus	98.28	0.00e+00	1087.00
IUUC-Mdo-063065	Monodelphis domestica	94.88	0.00e+00	1031.00
IUUC-Mmu-063829	Mus musculus	97.90	0.00e+00	1087.00
IUUC-Mac-065419	Musa acuminata	33.63	1.00e-76	280.00
IUUC-Mpu-066687	Mustela putorius furo	95.61	0.00e+00	1049.00
IUUC-Mlu-067330	Myotis lucifugus	81.63	0.00e+00	902.00
IUUC-Nfi-068423	Neosartorya fischeri	31.63	4.00e-57	215.00
IUUC-Ncr-068809	Neurospora crassa	29.72	8.00e-60	224.00
IUUC-Nle-069261	Nomascus leucogenys	95.62	0.00e+00	1047.00
IUUC-Opr-070469	Ochotona princeps	80.14	0.00e+00	692.00
IUUC-Ont-071961	Oreochromis niloticus	89.67	0.00e+00	974.00
IUUC-Oan-073565	Ornithorhynchus anatinus	86.55	0.00e+00	921.00
IUUC-Ocu-074435	Oryctolagus cuniculus	99.02	0.00e+00	1066.00
IUUC-Oba-075688	Oryza barthii	34.31	6.00e-77	281.00
IUUC-Obr-076652	Oryza brachyantha	41.69	6.00e-75	274.00
IUUC-Ogl-077910	Oryza glaberrima	34.23	2.00e-79	289.00
IUUC-Ogu-078479	Oryza glumaepatula	34.23	2.00e-79	289.00
IUUC-Oin-079697	Oryza indica	39.66	2.00e-76	279.00
IUUC-Olo-080811	Oryza longistaminata	41.38	3.00e-53	202.00
IUUC-Ome-081706	Oryza meridionalis	36.09	2.00e-78	287.00
IUUC-Oni-083070	Oryza nivara	33.87	3.00e-79	289.00
IUUC-Opu-083605	Oryza punctata	40.16	5.00e-68	251.00
IUUC-Oru-084522	Oryza rufipogon	34.23	2.00e-79	289.00
IUUC-Osa-085351	Oryza sativa	39.36	7.00e-77	281.00
IUUC-Ola-086743	Oryzias latipes	88.31	0.00e+00	754.00
IUUC-Olu-087695	Ostreococcus lucimarinus	31.54	5.00e-50	191.00
IUUC-Oga-089131	Otolemur garnettii	95.19	0.00e+00	1078.00
IUUC-Oar-089319	Ovis aries	98.08	0.00e+00	969.00
IUUC-Ptr-090783	Pan troglodytes	96.30	0.00e+00	984.00
IUUC-Pan-092927	Papio anubis	99.81	0.00e+00	1105.00
IUUC-Psi-093670	Pelodiscus sinensis	92.46	0.00e+00	954.00
IUUC-Pma-094323	Petromyzon marinus	69.92	0.00e+00	721.00
IUUC-Pno-095141	Phaeosphaeria nodorum	31.59	3.00e-57	216.00
IUUC-Ppa-095413	Physcomitrella patens	34.45	3.00e-80	292.00
IUUC-Pfo-096462	Poecilia formosa	89.87	0.00e+00	989.00
IUUC-Pab-097612	Pongo abelii	99.81	0.00e+00	1103.00
IUUC-Pop-099558	Populus trichocarpa	35.33	3.00e-89	322.00
IUUC-Pca-100329	Procavia capensis	81.52	0.00e+00	897.00
IUUC-Ppe-102020	Prunus persica	35.86	3.00e-93	335.00
IUUC-Pva-102409	Pteropus vampyrus	79.62	0.00e+00	847.00
IUUC-Pte-104340	Pyrenophora teres	32.29	1.00e-61	230.00
IUUC-Pyt-104782	Pyrenophora triticirepentis	33.67	1.00e-67	250.00
IUUC-Rno-105247	Rattus norvegicus	98.10	0.00e+00	1089.00
IUUC-Sce-106247	Saccharomyces cerevisiae	31.17	7.00e-52	197.00
IUUC-Sha-107538	Sarcophilus harrisii	96.31	6.00e-125	439.00
IUUC-Sja-107656	Schizosaccharomyces japonicus	34.16	8.00e-67	247.00
IUUC-Spo-108226	Schizosaccharomyces pombe	31.51	5.00e-61	228.00
IUUC-Ssl-108531	Sclerotinia sclerotiorum	32.14	1.00e-54	207.00
IUUC-Smo-109310	Selaginella moellendorffii	35.15	2.00e-86	312.00
IUUC-Sit-109716	Setaria italica	35.63	7.00e-80	291.00
IUUC-Sly-111077	Solanum lycopersicum	37.71	6.00e-83	301.00
IUUC-Stu-112203	Solanum tuberosum	40.09	6.00e-75	274.00
IUUC-Sar-113174	Sorex araneus	76.67	0.00e+00	791.00
IUUC-Sbi-114205	Sorghum bicolor	33.39	8.00e-81	294.00
IUUC-Ssc-115315	Sus scrofa	81.49	0.00e+00	894.00
IUUC-Tgu-116938	Taeniopygia guttata	96.38	0.00e+00	962.00
IUUC-Tru-117622	Takifugu rubripes	89.12	0.00e+00	991.00
IUUC-Tsy-119431	Tarsius syrichta	86.32	0.00e+00	822.00
IUUC-Tni-120661	Tetraodon nigroviridis	91.03	0.00e+00	999.00
IUUC-Tca-121154	Theobroma cacao	37.64	9.00e-92	330.00
IUUC-Tre-122139	Trichoderma reesei	33.26	4.00e-55	208.00
IUUC-Tvi-122599	Trichoderma virens	29.75	7.00e-57	214.00
IUUC-Tae-125608	Triticum aestivum	35.56	1.00e-86	313.00
IUUC-Tme-127115	Tuber melanosporum	37.33	1.00e-82	300.00
IUUC-Ttr-129006	Tursiops truncatus	81.85	0.00e+00	889.00
IUUC-Uma-129455	Ustilago maydis	31.97	1.00e-33	138.00
IUUC-Vda-129829	Verticillium dahliae	32.79	5.00e-36	144.00
IUUC-Vvi-131477	Vitis vinifera	35.83	4.00e-78	285.00
IUUC-Xtr-132444	Xenopus tropicalis	91.20	0.00e+00	1011.00
IUUC-Xma-133514	Xiphophorus maculatus	92.34	0.00e+00	1006.00
IUUC-Yli-134357	Yarrowia lipolytica	30.81	4.00e-48	185.00
IUUC-Zma-134945	Zea mays	34.95	5.00e-77	281.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence